digitoxin has been researched along with Arthritis* in 3 studies
3 other study(ies) available for digitoxin and Arthritis
Article | Year |
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[Kinetics of digitoxin during antirheumatic therapy with azapropazone (author's transl)].
The effect of chronic therapy with 5-dimethylamino-9-methylamino-9-methyl-2-propyl-1H-pyrazolo[1,2-a] [1,2,4] benzotriazine-1,3-(2H)-dione-dihydrate (azapropazone-dihydrate; Prolixan 300) on the elimination of a single i.v. dose of digitoxin was studied in 8 patients with rheumatoid arthritis and osteoarthritis using a crossover design. 0.5 mg digitoxin were injected i.v. alone and together with a chronic oral therapy of azapropazone starting 3 weeks before digitoxin was given. Digitoxin plasma levels were determined by radioimmunoassay over a period of 19 days. The half-life for plasma digitoxin was 6.4 +/- 0.5 days after digitoxin alone and 7.0 +/- 0.6 days during azapropazone treatment. In two patients the half-life of digitoxin was increased by about one-third during azapropazone therapy. The areas under the plasma digitoxin curve were 2592 +/- 262 ng/ml X h and 2615 +/- 273 ng/ml X h, respectively. None of the differences were statistically significant. It was concluded that there was no clinically significant interaction between azapropazone and a single dose of digitoxin. Topics: Adult; Apazone; Arthritis; Digitoxin; Drug Interactions; Half-Life; Humans; Kinetics; Middle Aged; Triazines | 1977 |
MEBUTAMATE AND HYDROCHLOROTHIAZIDE IN HYPERTENSION.
Topics: Antihypertensive Agents; Arthritis; Arthritis, Rheumatoid; Blood Pressure Determination; Carbamates; Coronary Disease; Diabetes Mellitus; Digitalis; Geriatrics; Hydrochlorothiazide; Hypertension; Nitroglycerin; Obesity; Parkinsonian Disorders; Prednisolone; Reserpine; Tolbutamide | 1964 |
Digitalis and splints for two digesters.
Topics: Arthritis; Digitalis; Digitalis Glycosides; Splints | 1949 |