digitonin has been researched along with Cardiomyopathies* in 1 studies
1 other study(ies) available for digitonin and Cardiomyopathies
| Article | Year |
|---|---|
Defective association of dystrophin with sarcolemmal glycoproteins in the cardiomyopathic hamster heart.
In ventricular muscle from 30- to 60-day-old Bio 14.6 cardiomyopathic hamsters, dystrophin-associated glycoproteins of 43, 50 and 150 kDa are markedly reduced in abundance. In particular, the 50-kDa glycoprotein is totally deficient in the sarcolemma of myopathic ventricular myocytes as revealed by immunofluorescence microscopy. The dystrophin-glycoprotein complex formation is defective in the cardiomyopathic hamster heart, because dystrophin and the glycoproteins behave independently when digitonin-solubilized ventricular homogenates are fractionated on wheat germ agglutinin beads or anti-dystrophin immunoaffinity beads. Topics: Animals; Cardiomyopathies; Cricetinae; Digitonin; Dystrophin; Fluorescent Antibody Technique; Glycoproteins; Heart Ventricles; Immunoblotting; Immunosorbent Techniques; Mesocricetus; Molecular Weight; Sarcolemma; Sodium-Potassium-Exchanging ATPase; Solubility; Wheat Germ Agglutinins | 1993 |