difluprednate and Pars-Planitis

To report the effects of twice-daily difluprednate in a child with pars planitis (PP).. Case report.. PP was controlled with topical difluprednate for 1 year. Then an atypical pattern of steroid response--delayed, relatively sudden onset of recalcitrant ocular hypertension (OHT)--and posterior subcapsular cataract (PSC) formation necessitated alternative treatment.. Although not a standard treatment, in select cases of PP topical difluprednate therapy could be a useful short-term treatment option while alternative treatments are considered or immunosuppressive agents build to therapeutic levels. Ophthalmologists must be aware of the potential for delayed onset of serious complications when using difluprednate.

Topics: Administration, Topical; Cataract; Child; Emulsions; Fluprednisolone; Glucocorticoids; Humans; Male; Ocular Hypertension; Pars Planitis; Prednisone; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Visual Acuity; Weight Gain