diflunisal has been researched along with Polyneuropathies in 1 studies
Diflunisal: A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.
diflunisal : An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.
Polyneuropathies: Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.
Excerpt | Relevance | Reference |
---|---|---|
" Herein, we report the diflunisal plasma concentrations measured by extraction, reversed phase HPLC separation, and fluorescence detection after long-term 250 mg BID oral dosing in two groups: a placebo-controlled diflunisal clinical trial group and an open-label Japanese polyneuropathy treatment cohort." | 1.91 | Characterising diflunisal as a transthyretin kinetic stabilizer at relevant concentrations in human plasma using subunit exchange. ( Berk, JL; Jäger, M; Kelly, JW; Kline, GM; Nelson, LT; Powers, ET; Sekijima, Y; Tsai, FJ, 2023) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (100.00) | 2.80 |
Authors | Studies |
---|---|
Tsai, FJ | 3 |
Nelson, LT | 3 |
Kline, GM | 3 |
Jäger, M | 3 |
Berk, JL | 3 |
Sekijima, Y | 3 |
Powers, ET | 3 |
Kelly, JW | 3 |
1 other study available for diflunisal and Polyneuropathies
Article | Year |
---|---|
Characterising diflunisal as a transthyretin kinetic stabilizer at relevant concentrations in human plasma using subunit exchange.
Topics: Amyloid Neuropathies, Familial; Anti-Inflammatory Agents, Non-Steroidal; Diflunisal; Excipients; Hum | 2023 |
Characterising diflunisal as a transthyretin kinetic stabilizer at relevant concentrations in human plasma using subunit exchange.
Topics: Amyloid Neuropathies, Familial; Anti-Inflammatory Agents, Non-Steroidal; Diflunisal; Excipients; Hum | 2023 |
Characterising diflunisal as a transthyretin kinetic stabilizer at relevant concentrations in human plasma using subunit exchange.
Topics: Amyloid Neuropathies, Familial; Anti-Inflammatory Agents, Non-Steroidal; Diflunisal; Excipients; Hum | 2023 |
Characterising diflunisal as a transthyretin kinetic stabilizer at relevant concentrations in human plasma using subunit exchange.
Topics: Amyloid Neuropathies, Familial; Anti-Inflammatory Agents, Non-Steroidal; Diflunisal; Excipients; Hum | 2023 |