diflunisal has been researched along with Kidney Failure, Chronic in 6 studies
Diflunisal: A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.
diflunisal : An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The single-dose plasma kinetics of diflunisal was studied in healthy young and old subjects, in patients with rheumatoid arthritis, and in patients with renal failure." | 7.67 | Influence of renal failure, rheumatoid arthritis and old age on the pharmacokinetics of diflunisal. ( Erikson, LO; Lindholm, L; Melander, A; Odar-Cederlöf, I; Wåhlin-Boll, E, 1989) |
| "The single-dose plasma kinetics of diflunisal was studied in healthy young and old subjects, in patients with rheumatoid arthritis, and in patients with renal failure." | 3.67 | Influence of renal failure, rheumatoid arthritis and old age on the pharmacokinetics of diflunisal. ( Erikson, LO; Lindholm, L; Melander, A; Odar-Cederlöf, I; Wåhlin-Boll, E, 1989) |
| " Formation of DF-plasma protein adducts in vivo was also found in rats and humans dosed with DF." | 1.28 | Reactivity of diflunisal acyl glucuronide in human and rat plasma and albumin solutions. ( Dickinson, RG; Watt, JA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adams, D | 1 |
| Cauquil, C | 1 |
| Théaudin, M | 1 |
| Verbeeck, RK | 2 |
| De Schepper, PJ | 1 |
| Faed, EM | 1 |
| Dickinson, RG | 2 |
| King, AR | 1 |
| Restifo, AC | 1 |
| Pond, SM | 1 |
| Watt, JA | 1 |
| Erikson, LO | 1 |
| Wåhlin-Boll, E | 1 |
| Odar-Cederlöf, I | 1 |
| Lindholm, L | 1 |
| Melander, A | 1 |
1 review available for diflunisal and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Familial amyloid polyneuropathies: therapeutic issues].
Topics: Amyloid Neuropathies, Familial; Antibodies, Monoclonal; Benzoxazoles; Clinical Trials as Topic; Difl | 2012 |
5 other studies available for diflunisal and Kidney Failure, Chronic
| Article | Year |
|---|---|
Influence of chronic renal failure and hemodialysis on diflunisal plasma protein binding.
Topics: Adult; Age Factors; Aged; Binding Sites; Blood Proteins; Diflunisal; Heparin; Humans; Kidney Failure | 1980 |
Decreased clearance of diflunisal in renal insufficiency--an alternative explanation.
Topics: Diflunisal; Glucuronates; Half-Life; Humans; Kidney Failure, Chronic; Salicylates | 1980 |
Diflunisal and its conjugates in patients with renal failure.
Topics: Adult; Diflunisal; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Middle Aged | 1991 |
Reactivity of diflunisal acyl glucuronide in human and rat plasma and albumin solutions.
Topics: Adult; Animals; Blood Proteins; Diflunisal; Female; Humans; Hydrolysis; Isomerism; Kidney Failure, C | 1990 |
Influence of renal failure, rheumatoid arthritis and old age on the pharmacokinetics of diflunisal.
Topics: Adolescent; Adult; Aged; Aging; Arthritis, Rheumatoid; Diflunisal; Female; Half-Life; Humans; Kidney | 1989 |