diflunisal has been researched along with Cardiac Failure in 5 studies
Diflunisal: A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.
diflunisal : An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diflunisal is an approved non-steroidal anti-inflammatory drug that stabilizes TTR, with limited data available regarding effects on cardiac structure and function." | 1.56 | Stabilization of Cardiac Function With Diflunisal in Transthyretin (ATTR) Cardiac Amyloidosis. ( Berk, JL; Connors, LH; Fox, J; Gopal, DM; Hellawell, J; Lohrmann, G; Maurer, MS; Mussinelli, R; Pipilas, A; Ruberg, FL; Siddiqi, OK; Vellanki, N, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lohrmann, G | 1 |
| Pipilas, A | 1 |
| Mussinelli, R | 1 |
| Gopal, DM | 1 |
| Berk, JL | 1 |
| Connors, LH | 1 |
| Vellanki, N | 1 |
| Hellawell, J | 1 |
| Siddiqi, OK | 1 |
| Fox, J | 1 |
| Maurer, MS | 3 |
| Ruberg, FL | 1 |
| Rubin, J | 1 |
| Sarswat, N | 1 |
| Adams, D | 1 |
| Cauquil, C | 1 |
| Théaudin, M | 1 |
| Castaño, A | 1 |
| Drachman, BM | 1 |
| Judge, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis[NCT06034405] | 1,663 participants (Anticipated) | Observational | 2023-09-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for diflunisal and Cardiac Failure
| Article | Year |
|---|---|
Cardiac Amyloidosis: Overlooked, Underappreciated, and Treatable.
Topics: Amyloid Neuropathies, Familial; Amyloidosis; Arrhythmias, Cardiac; Benzoates; Benzoxazoles; Biopsy; | 2020 |
[Familial amyloid polyneuropathies: therapeutic issues].
Topics: Amyloid Neuropathies, Familial; Antibodies, Monoclonal; Benzoxazoles; Clinical Trials as Topic; Difl | 2012 |
Natural history and therapy of TTR-cardiac amyloidosis: emerging disease-modifying therapies from organ transplantation to stabilizer and silencer drugs.
Topics: Amyloid Neuropathies, Familial; Benzoxazoles; Biomarkers; Cardiomyopathies; Cyclooxygenase Inhibitor | 2015 |
2 other studies available for diflunisal and Cardiac Failure
| Article | Year |
|---|---|
Stabilization of Cardiac Function With Diflunisal in Transthyretin (ATTR) Cardiac Amyloidosis.
Topics: Aged; Aged, 80 and over; Amyloid Neuropathies, Familial; Cardiomyopathies; Diflunisal; Female; Heart | 2020 |
An Orphan Disease No More: Additional Treatment Options for Cardiac Amyloidosis.
Topics: Amyloidosis; Cardiomyopathies; Diflunisal; Heart Failure; Humans; Prealbumin; Rare Diseases | 2020 |