Page last updated: 2024-10-26

diflunisal and Arthritis

diflunisal has been researched along with Arthritis in 5 studies

Diflunisal: A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.
diflunisal : An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.

Arthritis: Acute or chronic inflammation of JOINTS.

Research Excerpts

ExcerptRelevanceReference
"Diflunisal, a new analgesic/anti-inflammatory monosubstance, has been compared with naproxen in a double-blind study in patients with rheumatoid arthritis."9.05[Diflunisal compared with naproxen in chronic polyarthritis. Double-blind study]. ( Baumgartner, H; Boyle, CM, 1982)
"We report a case of neutropenia associated with the use of diflunisal."7.67Diflunisal-induced neutropenia. ( Begley, CG; Harris, RA; McLean, CA, 1986)
" Thus, the increase in diflunisal analgesic response in arthritis may be attributed to pharmacokinetic perturbations, resulting from alterations in serum protein binding and not to changes in drug pharmacodynamics."5.27Diflunisal pharmacodynamics in experimental arthritis in rats. ( Kasmerski, L; Walker, JS, 1988)
"Diflunisal, a new analgesic/anti-inflammatory monosubstance, has been compared with naproxen in a double-blind study in patients with rheumatoid arthritis."5.05[Diflunisal compared with naproxen in chronic polyarthritis. Double-blind study]. ( Baumgartner, H; Boyle, CM, 1982)
"20 patients with elevated serum uric acid levels and osteoarthritis of the hip or knee were given diflunisal 500 mg b."3.67[The uric acid-lowering effect of diflunisal]. ( Fasching, U, 1987)
"We report a case of neutropenia associated with the use of diflunisal."3.67Diflunisal-induced neutropenia. ( Begley, CG; Harris, RA; McLean, CA, 1986)
" Thus, the increase in diflunisal analgesic response in arthritis may be attributed to pharmacokinetic perturbations, resulting from alterations in serum protein binding and not to changes in drug pharmacodynamics."1.27Diflunisal pharmacodynamics in experimental arthritis in rats. ( Kasmerski, L; Walker, JS, 1988)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhalla, AK1
Simon, LS1
Baumgartner, H1
Boyle, CM1
Walker, JS1
Kasmerski, L1
Fasching, U1
McLean, CA1
Begley, CG1
Harris, RA1

Trials

1 trial available for diflunisal and Arthritis

ArticleYear
[Diflunisal compared with naproxen in chronic polyarthritis. Double-blind study].
    Schweizerische medizinische Wochenschrift, 1982, Feb-20, Volume: 112, Issue:8

    Topics: Adult; Aged; Arthritis; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Humans; M

1982

Other Studies

4 other studies available for diflunisal and Arthritis

ArticleYear
A clinical evaluation of the antiarthritic agents.
    Comprehensive therapy, 1984, Volume: 10, Issue:8

    Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis; Aspirin; Diflunisal; Fenoprofen; Glucocorticoids

1984
Diflunisal pharmacodynamics in experimental arthritis in rats.
    The Journal of rheumatology, 1988, Volume: 15, Issue:11

    Topics: Animals; Arthritis; Arthritis, Experimental; Diflunisal; Dose-Response Relationship, Drug; Injection

1988
[The uric acid-lowering effect of diflunisal].
    Wiener klinische Wochenschrift, 1987, Nov-20, Volume: 99, Issue:22

    Topics: Adolescent; Adult; Aged; Arthritis; Diflunisal; Female; Gout; Humans; Male; Middle Aged; Salicylates

1987
Diflunisal-induced neutropenia.
    Australian and New Zealand journal of medicine, 1986, Volume: 16, Issue:6

    Topics: Agranulocytosis; Arthritis; Diflunisal; Humans; Leukocyte Count; Male; Middle Aged; Neutropenia; Sal

1986