diflunisal has been researched along with Arthritis, Degenerative in 19 studies
Diflunisal: A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.
diflunisal : An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Despite a wide range of study designs, a multiplicity of international trials of diclofenac in osteoarthritis have disclosed similar results." | 9.06 | International experiences with diclofenac in osteoarthritis. ( Altman, R, 1986) |
| "A single blind randomized endoscopic study comparing the effects of diflunisal and naproxen on the gastric and duodenal mucosa of 34 patients with osteoarthritis was performed over a 2-week period." | 9.06 | A single blind randomized endoscopic study comparing the effects of diflunisal and naproxen in patients with osteoarthritis. ( Garber, EK; Guth, PH; Silpa, ML; Stolz, A, 1986) |
| "Thirty-one patients with osteoarthritis of the knee were treated with either diflunisal (n = 17) or naproxen (n = 14) in a 12-week open-label study." | 9.06 | Efficacy of diflunisal versus naproxen in osteoarthritis of the knee: an open study. ( Deal, CL; Moskowitz, RW, 1986) |
| "An open-label comparison of diflunisal, a nonacetylated salicylate nonsteroidal anti-inflammatory drug (NSAID), and piroxicam, an NSAID belonging to the oxicam family, was conducted in patients with osteoarthritis." | 9.06 | Comparison of diflunisal and piroxicam in the management of patients with osteoarthritis. ( Baumgartner, SW; Lain, D; Lewis, T, 1986) |
| "Fifty patients with osteoarthritis were studied in a double-blind, crossover trial of diflunisal (1000 mg daily) and naproxen (750 mg daily)." | 9.06 | A double-blind crossover trial of diflunisal and naproxen in osteoarthritis. ( De Jager, JP; Fleming, A; White, R, 1987) |
| "Diflunisal, a long acting antiinflammatory analgesic was compared in high (1000 mg daily) and low (750 mg daily) doses with placebo in a randomized, double blind study of 6 weeks' duration in patients with osteoarthritis of the knee." | 9.05 | The efficacy of diflunisal in osteoarthritis of the knee. A Canadian Multicenter Study. ( Davis, P; Lee, P; Prat, A, 1985) |
| "A randomized double-blind study in ambulatory patients with osteoarthritis of hip and/or knee was conducted, comparing the efficacy and safety of diflunisal 500 mg daily with ibuprofen 1200 mg daily, and a period of 8 weeks." | 9.04 | A comparative clinical trial of diflunisal and ibuprofen in the control of pain in osteoarthritis. ( Keet, JG, 1979) |
| "Diflunisal is a salicylic acid derivative with analgesic and anti-inflammatory activity." | 6.36 | Diflunisal: a review of its pharmacological properties and therapeutic use in pain and musculoskeletal strains and sprains and pain in osteoarthritis. ( Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM, 1980) |
| " Each dose was given for 14 days and diflunisal apparent oral clearance and serum urate was measured on the last day of each dosing regimen." | 5.27 | Diflunisal disposition and hypouricemic response in osteoarthritis. ( Bertouch, J; Brooks, PM; Harrington, BJ; Meffin, PJ; Veenendaal, JR, 1983) |
| "Despite a wide range of study designs, a multiplicity of international trials of diclofenac in osteoarthritis have disclosed similar results." | 5.06 | International experiences with diclofenac in osteoarthritis. ( Altman, R, 1986) |
| "A single blind randomized endoscopic study comparing the effects of diflunisal and naproxen on the gastric and duodenal mucosa of 34 patients with osteoarthritis was performed over a 2-week period." | 5.06 | A single blind randomized endoscopic study comparing the effects of diflunisal and naproxen in patients with osteoarthritis. ( Garber, EK; Guth, PH; Silpa, ML; Stolz, A, 1986) |
| "Thirty-one patients with osteoarthritis of the knee were treated with either diflunisal (n = 17) or naproxen (n = 14) in a 12-week open-label study." | 5.06 | Efficacy of diflunisal versus naproxen in osteoarthritis of the knee: an open study. ( Deal, CL; Moskowitz, RW, 1986) |
| "An open-label comparison of diflunisal, a nonacetylated salicylate nonsteroidal anti-inflammatory drug (NSAID), and piroxicam, an NSAID belonging to the oxicam family, was conducted in patients with osteoarthritis." | 5.06 | Comparison of diflunisal and piroxicam in the management of patients with osteoarthritis. ( Baumgartner, SW; Lain, D; Lewis, T, 1986) |
| "Fifty patients with osteoarthritis were studied in a double-blind, crossover trial of diflunisal (1000 mg daily) and naproxen (750 mg daily)." | 5.06 | A double-blind crossover trial of diflunisal and naproxen in osteoarthritis. ( De Jager, JP; Fleming, A; White, R, 1987) |
| "Diflunisal, a long acting antiinflammatory analgesic was compared in high (1000 mg daily) and low (750 mg daily) doses with placebo in a randomized, double blind study of 6 weeks' duration in patients with osteoarthritis of the knee." | 5.05 | The efficacy of diflunisal in osteoarthritis of the knee. A Canadian Multicenter Study. ( Davis, P; Lee, P; Prat, A, 1985) |
| "A randomized double-blind study in ambulatory patients with osteoarthritis of hip and/or knee was conducted, comparing the efficacy and safety of diflunisal 500 mg daily with ibuprofen 1200 mg daily, and a period of 8 weeks." | 5.04 | A comparative clinical trial of diflunisal and ibuprofen in the control of pain in osteoarthritis. ( Keet, JG, 1979) |
| "Sixty-two patients with osteoarthrosis entered a 10-week double-blind cross-over trial of diflunisal and naproxen." | 2.65 | Naproxen and diflunisal in osteoarthrosis. ( Brooks, PM; Dougan, MA; Hills, LJ; Smith, PJ; Thomas, D, 1982) |
| "Diflunisal is a salicylic acid derivative with analgesic and anti-inflammatory activity." | 2.36 | Diflunisal: a review of its pharmacological properties and therapeutic use in pain and musculoskeletal strains and sprains and pain in osteoarthritis. ( Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM, 1980) |
| " Each dose was given for 14 days and diflunisal apparent oral clearance and serum urate was measured on the last day of each dosing regimen." | 1.27 | Diflunisal disposition and hypouricemic response in osteoarthritis. ( Bertouch, J; Brooks, PM; Harrington, BJ; Meffin, PJ; Veenendaal, JR, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Omdal, R | 1 |
| Altman, RD | 1 |
| Seinfeld, H | 1 |
| Braun, HD | 1 |
| Gordin, A | 1 |
| Karppinen, I | 1 |
| Holttinen, K | 1 |
| Procházka, M | 1 |
| Schlumpf, U | 1 |
| Børkje, B | 1 |
| Meffin, PJ | 1 |
| Brooks, PM | 2 |
| Bertouch, J | 1 |
| Veenendaal, JR | 1 |
| Harrington, BJ | 1 |
| Brogden, RN | 1 |
| Heel, RC | 1 |
| Pakes, GE | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Dougan, MA | 1 |
| Thomas, D | 1 |
| Hills, LJ | 1 |
| Smith, PJ | 1 |
| Gross, D | 1 |
| Frei, M | 1 |
| Rau, R | 1 |
| Boussina, J | 1 |
| Keet, JG | 1 |
| Altman, R | 1 |
| Lee, P | 2 |
| Davis, P | 2 |
| Prat, A | 2 |
| Garber, EK | 1 |
| Guth, PH | 1 |
| Silpa, ML | 1 |
| Stolz, A | 1 |
| Deal, CL | 1 |
| Moskowitz, RW | 1 |
| Lewis, T | 1 |
| Lain, D | 1 |
| Baumgartner, SW | 1 |
| White, R | 1 |
| De Jager, JP | 1 |
| Fleming, A | 1 |
3 reviews available for diflunisal and Arthritis, Degenerative
| Article | Year |
|---|---|
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Toleran | 1984 |
[The introduction of non-steroidal antirheumatics: is there a rational therapy].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbazoles; Chronic Disease; Diclofe | 1982 |
Diflunisal: a review of its pharmacological properties and therapeutic use in pain and musculoskeletal strains and sprains and pain in osteoarthritis.
Topics: Diflunisal; Drug Interactions; Humans; Kinetics; Osteoarthritis; Pain; Salicylates; Sprains and Stra | 1980 |
15 trials available for diflunisal and Arthritis, Degenerative
| Article | Year |
|---|---|
[Naprosyn (naproxen) versus Donobid (diflunisal) in the treatment of osteoarthrosis of the hip and knee. A long-term study].
Topics: Adult; Aged; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Hip Joint; Humans; K | 1983 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Toleran | 1984 |
Comparison of slow-release indomethacin and diflunisal in patients with arthrosis.
Topics: Adult; Aged; Delayed-Action Preparations; Diflunisal; Female; Humans; Indomethacin; Male; Middle Age | 1984 |
[Diflunisal in the treatment of progressive polyarthritis and osteoarthritis].
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Diflunisal; Female; Humans; Male; Middle Age | 1982 |
[Diflunisal or naproxen in arthrosis. A double-blind study].
Topics: Adult; Aged; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Hip Joint; Humans; K | 1982 |
Naproxen and diflunisal in osteoarthrosis.
Topics: Aged; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Humans; Male; Naproxen; Ost | 1982 |
[Diflunisal in the treatment of coxarthrosis and gonarthrosis. A comparative double-blind study with acetylsalicylic acid].
Topics: Adult; Aged; Aspirin; Diflunisal; Double-Blind Method; Drug Evaluation; Female; Hip; Humans; Knee; M | 1980 |
A comparative clinical trial of diflunisal and ibuprofen in the control of pain in osteoarthritis.
Topics: Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Hip Joint; Humans; Ibuprofen; Kne | 1979 |
International experiences with diclofenac in osteoarthritis.
Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Dis | 1986 |
The efficacy of diflunisal in osteoarthritis of the knee: an extended study.
Topics: Clinical Trials as Topic; Diflunisal; Female; Humans; Knee; Male; Middle Aged; Osteoarthritis; Salic | 1986 |
A single blind randomized endoscopic study comparing the effects of diflunisal and naproxen in patients with osteoarthritis.
Topics: Adult; Aged; Clinical Trials as Topic; Diflunisal; Digestive System; Drug Tolerance; Endoscopy; Gast | 1986 |
Efficacy of diflunisal versus naproxen in osteoarthritis of the knee: an open study.
Topics: Adult; Aged; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Female; Humans; Knee Joint; Male; | 1986 |
Comparison of diflunisal and piroxicam in the management of patients with osteoarthritis.
Topics: Clinical Trials as Topic; Diflunisal; Drug Tolerance; Hip Joint; Humans; Knee Joint; Osteoarthritis; | 1986 |
A double-blind crossover trial of diflunisal and naproxen in osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Diflunisal; Double-Blind Method; Drug Administration Schedule; Femal | 1987 |
The efficacy of diflunisal in osteoarthritis of the knee. A Canadian Multicenter Study.
Topics: Adult; Aged; Clinical Trials as Topic; Diflunisal; Digestive System; Female; Humans; Knee Joint; Mal | 1985 |
2 other studies available for diflunisal and Arthritis, Degenerative
| Article | Year |
|---|---|
[Gon- and coxarthrosis. Therapy with diflunisal].
Topics: Adult; Aged; Diflunisal; Female; Hip Joint; Humans; Knee Joint; Male; Middle Aged; Osteoarthritis; S | 1983 |
Diflunisal disposition and hypouricemic response in osteoarthritis.
Topics: Aged; Chromatography, High Pressure Liquid; Creatinine; Diflunisal; Dose-Response Relationship, Drug | 1983 |