diflunisal has been researched along with Abnormalities, Drug-Induced in 2 studies
Diflunisal: A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.
diflunisal : An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These same dosage levels also caused a severe maternal hemolytic anemia following a dramatic decrease in erythrocyte ATP levels." | 1.27 | Diflunisal-induced maternal anemia as a cause of teratogenicity in rabbits. ( Allen, HL; Bokelman, DL; Clark, RL; Cohen, SM; James, ML; Minsker, DH; Robertson, RT; Tocco, DJ, 1984) |
| " The plasma elimination half-life was calculated to be 10." | 1.27 | Evaluation of the teratogenicity and pharmacokinetics of diflunisal in cynomolgus monkeys. ( Cukierski, M; Hendrickx, AG; Prahalada, S; Robertson, RT; Rowland, JM; Tocco, D, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clark, RL | 1 |
| Robertson, RT | 2 |
| Minsker, DH | 1 |
| Cohen, SM | 1 |
| Tocco, DJ | 1 |
| Allen, HL | 1 |
| James, ML | 1 |
| Bokelman, DL | 1 |
| Rowland, JM | 1 |
| Cukierski, M | 1 |
| Prahalada, S | 1 |
| Tocco, D | 1 |
| Hendrickx, AG | 1 |
2 other studies available for diflunisal and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Diflunisal-induced maternal anemia as a cause of teratogenicity in rabbits.
Topics: Abnormalities, Drug-Induced; Adenosine Triphosphate; Anemia, Hemolytic; Animals; Antioxidants; Aspir | 1984 |
Evaluation of the teratogenicity and pharmacokinetics of diflunisal in cynomolgus monkeys.
Topics: Abnormalities, Drug-Induced; Animals; Diflunisal; Dose-Response Relationship, Drug; Embryo, Mammalia | 1987 |