diethylnitrosamine has been researched along with Iron Overload in 3 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diethylnitrosamine (DEN) was administered to rats as a single dose, which is known not to give rise to liver tumours without subsequent promotion." | 1.30 | Iron promotes DEN initiated GST-P foci in rat liver. ( Carthew, P; Edwards, RE; Nolan, BM; Smith, AG, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mizukami, S | 1 |
| Ichimura, R | 1 |
| Kemmochi, S | 1 |
| Wang, L | 1 |
| Taniai, E | 1 |
| Mitsumori, K | 1 |
| Shibutani, M | 1 |
| Turlin, B | 1 |
| Le Quilleuc, D | 1 |
| Leroyer, P | 1 |
| Brissot, P | 1 |
| Deugnier, Y | 1 |
| Loréal, O | 1 |
| Carthew, P | 1 |
| Nolan, BM | 1 |
| Smith, AG | 1 |
| Edwards, RE | 1 |
3 other studies available for diethylnitrosamine and Iron Overload
| Article | Year |
|---|---|
Tumor promotion by copper-overloading and its enhancement by excess iron accumulation involving oxidative stress responses in the early stage of a rat two-stage hepatocarcinogenesis model.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Copper; Diethylnitrosamine; Glutathione Transferase; Im | 2010 |
High vascular endothelial growth factor (VEGF) expression in chemically-induced hepatic microcancers in mice.
Topics: Alkylating Agents; Animals; Diethylnitrosamine; Disease Models, Animal; Endothelial Growth Factors; | 2002 |
Iron promotes DEN initiated GST-P foci in rat liver.
Topics: Animals; Biomarkers; Body Weight; Carcinogens; Chemical and Drug Induced Liver Injury; Diethylnitros | 1997 |