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diethylnitrosamine and Invasiveness, Neoplasm

diethylnitrosamine has been researched along with Invasiveness, Neoplasm in 14 studies

Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.

Research Excerpts

ExcerptRelevanceReference
" Here, we investigated the roles of insulin receptor substrate (Irs) 1 and Irs2, both of which are the major molecules to be responsible for transducing insulin/IGF signaling in the liver, in the development of HCC by inducing chemical carcinogenesis using diethylnitrosamine (DEN) in mice."3.85Role of insulin receptor substrates in the progression of hepatocellular carcinoma. ( Aihara, M; Hayashi, T; Iwamoto, M; Kadowaki, T; Kubota, N; Kubota, T; Nishihara, H; Obata, A; Sakurai, Y; Takamoto, I, 2017)
"Cell nuclear DNA ploidy patterns were examined using cytofluorometry in hepatocellular carcinomas (HCC) induced by diethylnitrosamine (DEN) in rat and human HCC."3.67[Biological activity of hepatocellular carcinoma by analysing nuclear DNA ploidy patterns and using anti BrdU monoclonal antibody]. ( Jung-Rou, T, 1989)
"Dieckol (DEK) is a major polyphenol of marine brown seaweed Ecklonia cava which is a potential candidate for cancer therapy."1.46Modulatory efficacy of dieckol on xenobiotic-metabolizing enzymes, cell proliferation, apoptosis, invasion and angiogenesis during NDEA-induced rat hepatocarcinogenesis. ( Duraikannu, A; Fredrick, WS; Gobalakrishnan, R; Kodisundaram, P; Ravichandran, S; Sadeeshkumar, V, 2017)
"The high recurrence/metastasis of HCC is the main cause of death for HCC patients after liver resection."1.46miR-203 inhibits augmented proliferation and metastasis of hepatocellular carcinoma residual in the promoted regenerating liver. ( Chen, XB; Feng, L; Tang, JW; Xu, LL; Xu, MQ; Yi, PS; Zhang, M; Zheng, XB, 2017)
"After DEN-induced hepatocellular carcinoma (HCC) in rats showed increased phosphorylation of JNK1/2, p38, and ERK1/2, we next antagonized TGF-β1-induced phosphorylation of JNK1/2, p38, ERK1/2, Smad2/3 signaling in HepG2 cells using SP600125, SB203580, and PD98059, respectively."1.42MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells. ( Boye, A; He, S; Jiang, Y; Kan, H; Wu, C; Yang, X; Yang, Y, 2015)
"Carvacrol is a predominant monoterpenoic phenol believed to impede cancer promotion and progression."1.40Carvacrol modulates instability of xenobiotic metabolizing enzymes and downregulates the expressions of PCNA, MMP-2, and MMP-9 during diethylnitrosamine-induced hepatocarcinogenesis in rats. ( Balan, R; Krishnan, G; Mani, GK; Mgj, D; Ramalingam, S; Ramasamy, E; Subramaniyan, J; Thandavamoorthy, P; Thiruvengadam, D; Veerabathiran, R, 2014)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's0 (0.00)18.2507
2000's4 (28.57)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sadeeshkumar, V1
Duraikannu, A1
Ravichandran, S1
Kodisundaram, P1
Fredrick, WS1
Gobalakrishnan, R1
Sakurai, Y1
Kubota, N1
Takamoto, I1
Obata, A1
Iwamoto, M1
Hayashi, T1
Aihara, M1
Kubota, T1
Nishihara, H1
Kadowaki, T1
Hu, X1
Rui, W1
Wu, C2
He, S2
Jiang, J1
Zhang, X1
Yang, Y2
Subramaniyan, J1
Krishnan, G1
Balan, R1
Mgj, D1
Ramasamy, E1
Ramalingam, S1
Veerabathiran, R1
Thandavamoorthy, P1
Mani, GK1
Thiruvengadam, D1
Boye, A1
Kan, H1
Jiang, Y1
Yang, X1
Zheng, XB1
Chen, XB1
Xu, LL1
Zhang, M1
Feng, L1
Yi, PS1
Tang, JW1
Xu, MQ1
Piskunova, TS1
Zabezhinskiĭ, MA1
Popovich, IG1
Tyndyk, ML1
Iurova, MN1
Anisimov, VN1
Srivastava, J1
Siddiq, A1
Emdad, L1
Santhekadur, PK1
Chen, D2
Gredler, R1
Shen, XN1
Robertson, CL1
Dumur, CI1
Hylemon, PB1
Mukhopadhyay, ND1
Bhere, D1
Shah, K1
Ahmad, R1
Giashuddin, S1
Stafflinger, J1
Subler, MA1
Windle, JJ1
Fisher, PB1
Sarkar, D1
Zimmers, TA1
Jin, X1
Gutierrez, JC1
Acosta, C1
McKillop, IH1
Pierce, RH1
Koniaris, LG1
Chen, H1
Diao, L1
Li, H1
Liu, M1
Hashimoto, S1
Sueishi, K1
Thiyagarajah, A1
Grizzle, JM1
Jung-Rou, T1
De Ridder, L1
Mosselmans, R1
Bernaert, D1
Galand, P1

Reviews

1 review available for diethylnitrosamine and Invasiveness, Neoplasm

ArticleYear
[Basic research on lung cancer].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 5

    Topics: Animals; Diethylnitrosamine; Disease Models, Animal; Genes, Tumor Suppressor; Growth Substances; His

2002

Other Studies

13 other studies available for diethylnitrosamine and Invasiveness, Neoplasm

ArticleYear
Modulatory efficacy of dieckol on xenobiotic-metabolizing enzymes, cell proliferation, apoptosis, invasion and angiogenesis during NDEA-induced rat hepatocarcinogenesis.
    Molecular and cellular biochemistry, 2017, Volume: 433, Issue:1-2

    Topics: Animals; Apoptosis; Benzofurans; Cell Proliferation; Cell Transformation, Neoplastic; Diethylnitrosa

2017
Role of insulin receptor substrates in the progression of hepatocellular carcinoma.
    Scientific reports, 2017, 07-14, Volume: 7, Issue:1

    Topics: Animals; beta Catenin; Carcinogenesis; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Progre

2017
Compound Astragalus and Salvia miltiorrhiza extracts suppress hepatocarcinogenesis by modulating transforming growth factor-β/Smad signaling.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:6

    Topics: Animals; Astragalus Plant; Carcinoma, Hepatocellular; Diethylnitrosamine; Dose-Response Relationship

2014
Carvacrol modulates instability of xenobiotic metabolizing enzymes and downregulates the expressions of PCNA, MMP-2, and MMP-9 during diethylnitrosamine-induced hepatocarcinogenesis in rats.
    Molecular and cellular biochemistry, 2014, Volume: 395, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Cell Proliferation; Cymenes; Diethylnitrosamine;

2014
MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:5

    Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; Diethylnitrosamine; Flavonoi

2015
miR-203 inhibits augmented proliferation and metastasis of hepatocellular carcinoma residual in the promoted regenerating liver.
    Cancer science, 2017, Volume: 108, Issue:3

    Topics: Animals; Calpain; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Diethylnitrosamine;

2017
[Diethylnitrosamine-induced carcinogenesis in PARP-1(-/-) and PARP-1(+/+) mice].
    Voprosy onkologii, 2009, Volume: 55, Issue:5

    Topics: Animals; Carcinogens; Cholangiocarcinoma; Diethylnitrosamine; DNA Repair; Female; Hemangiosarcoma; I

2009
Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model.
    Hepatology (Baltimore, Md.), 2012, Volume: 56, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Adhesion Molecules; Cell Transformat

2012
Effect of in vivo loss of GDF-15 on hepatocellular carcinogenesis.
    Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:7

    Topics: Alkylating Agents; Animals; Carcinoma, Hepatocellular; Cytokines; Diethylnitrosamine; Growth Differe

2008
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2002, Volume: 24, Issue:2

    Topics: Alkylating Agents; Animals; Carcinoma, Squamous Cell; Diethylnitrosamine; Female; Gene Expression Re

2002
Diethylnitrosamine-induced pancreatic neoplasms in the fish Rivulus ocellatus marmoratus.
    Journal of the National Cancer Institute, 1986, Volume: 77, Issue:1

    Topics: Adenocarcinoma; Adenoma; Animals; Cystadenoma; Diethylnitrosamine; Dose-Response Relationship, Drug;

1986
[Biological activity of hepatocellular carcinoma by analysing nuclear DNA ploidy patterns and using anti BrdU monoclonal antibody].
    Nihon Geka Gakkai zasshi, 1989, Volume: 90, Issue:2

    Topics: Aged; Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Nucleus; D

1989
Invasiveness, proliferative activity and ultrastructural phenotypes of hepatocytes from diethylnitrosamine-induced neoplastic nodules and hepacarcinomas in vitro.
    International journal of cancer, 1987, Nov-15, Volume: 40, Issue:5

    Topics: Animals; Autoradiography; Cell Division; Chick Embryo; Diethylnitrosamine; In Vitro Techniques; Live

1987