diethylnitrosamine has been researched along with Hepatoblastoma in 4 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Hepatoblastoma: A malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We established a cell line (MHB-2) from a hepatoblastoma (HB) induced by diethylnitrosamine (DEN) and sodium phenobarbital (PB) in male B6C3F1 mice and examined the biological characteristics of MHB-2." | 3.70 | Establishment and characterization of a cell line from a chemically-induced mouse hepatoblastoma. ( Goto, K; Kobayashi, K; Mutai, M; Sakairi, T; Sugimoto, J; Tsuchiya, T, 2000) |
| "In previous studies, we found that male D2B6F1 mice fed phenobarbital (PB) for 53 weeks following N-nitrosodiethylamine (NDEA) initiation developed a high (70-80%) incidence of malignant hepatoblastomas." | 3.69 | Further evidence for promoter-dependent development of hepatoblastoma in the mouse. ( Diwan, BA; Henneman, JR; Rice, JM, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Valanejad, L | 1 |
| Lewis, K | 1 |
| Wright, M | 1 |
| Jiang, Y | 1 |
| D'Souza, A | 1 |
| Karns, R | 1 |
| Sheridan, R | 1 |
| Gupta, A | 1 |
| Bove, K | 1 |
| Witte, D | 1 |
| Geller, J | 1 |
| Tiao, G | 1 |
| Nelson, DL | 1 |
| Timchenko, L | 1 |
| Timchenko, N | 1 |
| Diwan, BA | 2 |
| Henneman, JR | 2 |
| Rice, JM | 2 |
| Nims, RW | 1 |
| Kobayashi, K | 1 |
| Sakairi, T | 1 |
| Goto, K | 1 |
| Tsuchiya, T | 1 |
| Sugimoto, J | 1 |
| Mutai, M | 1 |
4 other studies available for diethylnitrosamine and Hepatoblastoma
| Article | Year |
|---|---|
FXR-Gankyrin axis is involved in development of pediatric liver cancer.
Topics: Animals; CELF1 Protein; Cell Differentiation; Cell Line, Tumor; Diethylnitrosamine; Gene Expression | 2017 |
Further evidence for promoter-dependent development of hepatoblastoma in the mouse.
Topics: Animals; Cocarcinogenesis; Diethylnitrosamine; Female; Hepatoblastoma; Liver Neoplasms, Experimental | 1995 |
Tumor promotion by an anticonvulsant agent, phenytoin, in mouse liver: correlation with CYP2B induction.
Topics: Adenoma; Animals; Body Weight; Carcinogens; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; | 1993 |
Establishment and characterization of a cell line from a chemically-induced mouse hepatoblastoma.
Topics: Animals; Carcinogens; Cell Line; Diethylnitrosamine; Disease Models, Animal; Hepatoblastoma; Liver N | 2000 |