Page last updated: 2024-11-08

diethylnitrosamine and Hepatitis

diethylnitrosamine has been researched along with Hepatitis in 18 studies

Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.

Hepatitis: INFLAMMATION of the LIVER.

Research Excerpts

ExcerptRelevanceReference
" Furthermore, Shp2 ablation dramatically enhanced diethylnitrosamine (DEN)-induced hepatocellular carcinoma (HCC) development, which was abolished by concurrent deletion of Shp2 and Stat3 in hepatocytes."3.77Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis. ( Bailly-Maitre, B; Bard-Chapeau, EA; Ding, J; Fang, DD; Feng, GS; Han, T; Li, S; Poli, V; Princen, F; Varki, NM; Wang, H; Zhang, SS; Zhu, HH, 2011)
"In fact, liver cancer often develops in the context of chronic liver injury."2.53Liver carcinogenesis: from naughty chemicals to soothing fat and the surprising role of NRF2. ( Dhar, D; Karin, M, 2016)
"TREM-2 plays a protective role in hepatocarcinogenesis via different pleiotropic effects, suggesting that TREM-2 agonism should be investigated as it might beneficially impact HCC pathogenesis in a multifactorial manner."1.62TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms. ( Agirre-Lizaso, A; Andersen, JB; Aspichueta, P; Azkargorta, M; Banales, JM; Bujanda, L; Elortza, F; Esparza-Baquer, A; Hijona, E; Jimenez-Agüero, R; Knapp, S; La Casta, A; Labiano, I; Landa, A; Mann, DA; Munoz-Garrido, P; O'Rourke, CJ; Oakley, F; Perugorria, MJ; Riaño, I; Rodrigues, PM; Schabbauer, G; Sharif, O; Vogel, A; Zaki, MYW; Zhuravleva, E, 2021)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's1 (5.56)18.2507
2000's0 (0.00)29.6817
2010's12 (66.67)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Lai, Y1
Zhang, T1
Huang, L1
Li, W1
Lin, W1
Esparza-Baquer, A1
Labiano, I1
Sharif, O1
Agirre-Lizaso, A1
Oakley, F1
Rodrigues, PM1
Zhuravleva, E1
O'Rourke, CJ1
Hijona, E1
Jimenez-Agüero, R1
Riaño, I1
Landa, A1
La Casta, A1
Zaki, MYW1
Munoz-Garrido, P1
Azkargorta, M1
Elortza, F1
Vogel, A1
Schabbauer, G1
Aspichueta, P1
Andersen, JB1
Knapp, S1
Mann, DA1
Bujanda, L1
Banales, JM1
Perugorria, MJ1
Ploeger, JM1
Manivel, JC1
Boatner, LN1
Mashek, DG1
Kessler, SM1
Hoppstädter, J1
Hosseini, K1
Laggai, S1
Haybaeck, J1
Kiemer, AK1
Borst, K1
Graalmann, T1
Kalinke, U1
Ip, BC1
Liu, C1
Smith, DE1
Ausman, LM1
Wang, XD1
Fang, JZ1
Li, C1
Liu, XY1
Hu, TT1
Fan, ZS1
Han, ZG1
Karin, M2
Dhar, D1
Tien, AJ1
Chien, CY1
Chen, YH1
Lin, LC1
Chien, CT1
Ding, YF1
Wu, ZH1
Wei, YJ1
Shu, L1
Peng, YR1
Park, EJ1
Lee, JH1
Yu, GY1
He, G1
Ali, SR1
Holzer, RG1
Osterreicher, CH1
Takahashi, H2
Llorente Izquierdo, C1
Mayoral, R1
Flores, JM1
García-Palencia, P1
Cucarella, C1
Boscá, L1
Casado, M1
Martín-Sanz, P1
Bard-Chapeau, EA1
Li, S1
Ding, J1
Zhang, SS1
Zhu, HH1
Princen, F1
Fang, DD1
Han, T1
Bailly-Maitre, B1
Poli, V1
Varki, NM1
Wang, H1
Feng, GS1
Heindryckx, F1
Kuchnio, A1
Casteleyn, C1
Coulon, S1
Olievier, K1
Colle, I1
Geerts, A1
Libbrecht, L1
Carmeliet, P1
Van Vlierberghe, H1
SYDOW, G1
SCHMAEHL, D1
THOMAS, C1
SATTLER, W1
STANTON, MF1
Enomoto, K1
Nakajima, Y1
Mori, M1

Reviews

1 review available for diethylnitrosamine and Hepatitis

ArticleYear
Liver carcinogenesis: from naughty chemicals to soothing fat and the surprising role of NRF2.
    Carcinogenesis, 2016, Volume: 37, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Diet, High-Fat; Diethylnitrosamine; Disease Models, Animal; Hepa

2016

Other Studies

17 other studies available for diethylnitrosamine and Hepatitis

ArticleYear
Monitoring cell viability in N-nitrosodiethylamine induced acute hepatitis and detection of hydrazine in solution and gas phase with Dual-function fluorescent probes.
    Journal of hazardous materials, 2023, 02-05, Volume: 443, Issue:Pt B

    Topics: Animals; Cell Survival; Diethylnitrosamine; Esterases; Fluorescent Dyes; Hepatitis; Hydrazines; Mice

2023
TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms.
    Gut, 2021, Volume: 70, Issue:7

    Topics: Adult; Aged; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferatio

2021
Caloric Restriction Prevents Carcinogen-Initiated Liver Tumorigenesis in Mice.
    Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:11

    Topics: Animals; Caloric Restriction; Carcinogenesis; Carcinogens; Chemical and Drug Induced Liver Injury; D

2017
Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation.
    Journal of hepatology, 2019, Volume: 70, Issue:4

    Topics: Diethylnitrosamine; Hepatitis; Humans; Inflammation; Kupffer Cells; Liver; Receptor, Interferon alph

2019
Reply to: "Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation".
    Journal of hepatology, 2019, Volume: 70, Issue:4

    Topics: Diethylnitrosamine; Hepatitis; Humans; Inflammation; Kupffer Cells; Receptor, Interferon alpha-beta

2019
High-refined-carbohydrate and high-fat diets induce comparable hepatic tumorigenesis in male mice.
    The Journal of nutrition, 2014, Volume: 144, Issue:5

    Topics: Animals; Apoptosis; Carcinogens; Carcinoma, Hepatocellular; Dietary Carbohydrates; Dietary Fats; Die

2014
Hepatocyte-Specific Arid1a Deficiency Initiates Mouse Steatohepatitis and Hepatocellular Carcinoma.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cytokines; Diethylnitrosamine; DNA-Binding Prote

2015
Fruiting Bodies of Antrodia cinnamomea and Its Active Triterpenoid, Antcin K, Ameliorates N-Nitrosodiethylamine-Induced Hepatic Inflammation, Fibrosis and Carcinogenesis in Rats.
    The American journal of Chinese medicine, 2017, Volume: 45, Issue:1

    Topics: Alkylating Agents; Animals; Antrodia; Apoptosis; Autophagy; Carcinogenesis; Carcinoma, Hepatocellula

2017
Hepatic inflammation-fibrosis-cancer axis in the rat hepatocellular carcinoma induced by diethylnitrosamine.
    Journal of cancer research and clinical oncology, 2017, Volume: 143, Issue:5

    Topics: Animals; Chemical and Drug Induced Liver Injury; Diethylnitrosamine; Disease Progression; Hepatitis;

2017
Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression.
    Cell, 2010, Jan-22, Volume: 140, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cell Proliferation; Diethylnitrosamine; Extracellular Signal-Reg

2010
Transgenic mice expressing cyclooxygenase-2 in hepatocytes reveal a minor contribution of this enzyme to chemical hepatocarcinogenesis.
    The American journal of pathology, 2011, Volume: 178, Issue:3

    Topics: Aging; Animals; Body Weight; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin E; Cyclooxy

2011
Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis.
    Cancer cell, 2011, May-17, Volume: 19, Issue:5

    Topics: Adenoma, Liver Cell; Animals; Carcinoma, Hepatocellular; Cytokines; Diethylnitrosamine; Gene Express

2011
Effect of prolyl hydroxylase domain-2 haplodeficiency on the hepatocarcinogenesis in mice.
    Journal of hepatology, 2012, Volume: 57, Issue:1

    Topics: Alkylating Agents; Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular

2012
[THE HEXOKINASE ACTIVITY IN THE MITOCHONDRIA OF THE PRECANCEROUS RAT LIVER AND TRANSPLANTED DIETHYLNITROSAMINE HEPATOMA].
    Acta biologica et medica Germanica, 1964, Volume: 13

    Topics: Carcinogens; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Diethylnitrosamine;

1964
[HEPATOTOXIC AND CIRRHOGENIC EFFECT OF DIETHYLNITROSAMINE IN DOGS].
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Chemical and Drug Induced Liver Injury; Diethylnitrosamine; Dogs; Gastrointestinal Diseases; Hepatit

1964
DIETHYLNITROSAMINE-INDUCED HEPATIC DEGENERATION AND NEOPLASIA IN THE AQUARIUM FISH, BRACHYDANIO RERIO.
    Journal of the National Cancer Institute, 1965, Volume: 34

    Topics: Animals; Carcinogens; Chemical and Drug Induced Liver Injury; Diethylnitrosamine; Fishes; Hepatitis;

1965
High sensitivity of the LEC rat liver to the carcinogenic effect of diethylnitrosamine.
    Cancer letters, 1990, Jun-15, Volume: 51, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Diethylnitrosamine; Environmental Pollutants; Female; Glutathione Tr

1990