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diethylnitrosamine and Hepatitis, Animal

diethylnitrosamine has been researched along with Hepatitis, Animal in 4 studies

Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.

Hepatitis, Animal: INFLAMMATION of the LIVER in non-human animals.

Research Excerpts

ExcerptRelevanceReference
"Hepatitis and hepatocellular carcinoma are serious human diseases."1.51Extracts of Qizhu decoction inhibit hepatitis and hepatocellular carcinoma in vitro and in C57BL/6 mice by suppressing NF-κB signaling. ( Fang, NY; Shen, JJ; Wan, LF; Wang, YH; Xue, BY; Yuan, X; Zhao, W, 2019)
"Experimentally induced hepatocellular carcinoma is considered one of the representative laboratory models for studying this process."1.42Dynamic metabolic change is indicative of inflammation-induced transformation of hepatic cells. ( Cai, JC; Cathopoulis, T; Han, R; Li, X; Liu, F; Liu, GY; Lu, K; Luo, G; Peng, B; Shi, SL; Yang, L, 2015)
"These results suggested that LEC rat hepatocellular carcinoma could be naturally initiated after the onset of hepatitis by carcinogens contaminating food and the environment, probably due to the reduction of DNA repair activity, after which initiated hepatocytes selectively proliferate in response to growth stimuli endogenously produced as a result of continuous loss of hepatocytes (chronic hepatitis), because of a decrease in growth activity of non-initiated hepatocytes."1.29High sensitivity of LEC rats with chronic hepatitis to hepatocarcinogenesis: decreases in unscheduled and replicative DNA synthesis of the hepatocytes. ( Enomoto, K; Kamimura, Y; Mori, M; Sakamoto, H; Sawada, N, 1993)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wan, LF1
Shen, JJ1
Wang, YH1
Zhao, W1
Fang, NY1
Yuan, X1
Xue, BY1
Peng, B1
Liu, F1
Han, R1
Luo, G1
Cathopoulis, T1
Lu, K1
Li, X1
Yang, L1
Liu, GY1
Cai, JC1
Shi, SL1
Li, W1
Xiao, J1
Zhou, X1
Xu, M1
Hu, C1
Xu, X1
Lu, Y1
Liu, C1
Xue, S1
Nie, L1
Zhang, H1
Li, Z1
Zhang, Y1
Ji, F1
Hui, L1
Tao, W1
Wei, B1
Wang, H1
Sakamoto, H1
Sawada, N1
Kamimura, Y1
Enomoto, K1
Mori, M1

Other Studies

4 other studies available for diethylnitrosamine and Hepatitis, Animal

ArticleYear
Extracts of Qizhu decoction inhibit hepatitis and hepatocellular carcinoma in vitro and in C57BL/6 mice by suppressing NF-κB signaling.
    Scientific reports, 2019, 02-05, Volume: 9, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Models, Animal; Drugs, Chinese Herba

2019
Dynamic metabolic change is indicative of inflammation-induced transformation of hepatic cells.
    The international journal of biochemistry & cell biology, 2015, Volume: 66

    Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chemical and

2015
STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.
    The Journal of clinical investigation, 2015, Nov-02, Volume: 125, Issue:11

    Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cytokines; Diethylnitrosamine; Escherichia

2015
High sensitivity of LEC rats with chronic hepatitis to hepatocarcinogenesis: decreases in unscheduled and replicative DNA synthesis of the hepatocytes.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:9

    Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Chronic Disease; Diethylnitrosamine; DNA; Epiderm

1993