diethylnitrosamine has been researched along with Genome Instability in 6 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diethylnitrosamine (DEN) is a hepatic procarcinogen which is frequently used as an inducer of hepatocellular carcinoma (HCC) in mice." | 3.77 | Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice. ( Aleksic, K; Auer, M; Fischer, M; Geigl, JB; Lackner, C; Otte, M; Schwarz, M; Speicher, MR; Trajanoski, Z; Ulz, P, 2011) |
| " In the present study, we showed that MAP1S levels immediately become elevated in response to diethylnitrosamine-induced or genome instability-driven metabolic stress in a murine model of hepatocarcinoma." | 3.77 | Autophagy enhanced by microtubule- and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis. ( Liu, L; McKeehan, WL; Wang, F; Xie, R, 2011) |
| "A mouse model of fibrosis-associated liver cancer that was designed to emulate cirrhotic liver, a prevailing disease state observed in most humans with HCC, was used." | 1.40 | Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice. ( Beland, FA; Chappell, G; Hoenerhoff, M; Hong, HH; Kutanzi, K; Pogribny, IP; Rusyn, I; Tryndyak, V; Uehara, T, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chung, YL | 1 |
| Wu, ML | 1 |
| Chappell, G | 1 |
| Kutanzi, K | 1 |
| Uehara, T | 1 |
| Tryndyak, V | 1 |
| Hong, HH | 1 |
| Hoenerhoff, M | 1 |
| Beland, FA | 1 |
| Rusyn, I | 1 |
| Pogribny, IP | 1 |
| Calvisi, DF | 1 |
| Aleksic, K | 1 |
| Lackner, C | 1 |
| Geigl, JB | 1 |
| Schwarz, M | 1 |
| Auer, M | 1 |
| Ulz, P | 1 |
| Fischer, M | 1 |
| Trajanoski, Z | 1 |
| Otte, M | 1 |
| Speicher, MR | 1 |
| McClendon, AK | 1 |
| Dean, JL | 1 |
| Ertel, A | 1 |
| Fu, Z | 1 |
| Rivadeneira, DB | 1 |
| Reed, CA | 1 |
| Bourgo, RJ | 1 |
| Witkiewicz, A | 1 |
| Addya, S | 1 |
| Mayhew, CN | 1 |
| Grimes, HL | 1 |
| Fortina, P | 1 |
| Knudsen, ES | 1 |
| Xie, R | 1 |
| Wang, F | 1 |
| McKeehan, WL | 1 |
| Liu, L | 1 |
6 other studies available for diethylnitrosamine and Genome Instability
| Article | Year |
|---|---|
Promyelocytic leukaemia protein links DNA damage response and repair to hepatitis B virus-related hepatocarcinogenesis.
Topics: Adiposity; Animals; Antibiotics, Antineoplastic; Biomarkers; Biopsy; Carcinoma, Hepatocellular; Cell | 2013 |
Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice.
Topics: Animals; beta Catenin; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Transformation, Neoplas | 2014 |
Of mice and men: the nonrandom genomic instability in hepatocarcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Diethylnitrosamine; Genes, myc; | 2011 |
Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice.
Topics: Animals; beta Catenin; Carcinoma, Hepatocellular; Comparative Genomic Hybridization; Core Binding Fa | 2011 |
RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage.
Topics: Animals; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Chromosome Aberrations; Comparat | 2011 |
Autophagy enhanced by microtubule- and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis.
Topics: Alkylating Agents; Animals; Autophagy; Cell Transformation, Neoplastic; Diethylnitrosamine; DNA Brea | 2011 |