diethylnitrosamine has been researched along with Genetic Predisposition in 22 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Liver tumor, especially hepatocellular carcinoma (HCC), is closely associated with chronic inflammation." | 1.38 | Deletion of IFNγ enhances hepatocarcinogenesis in FXR knockout mice. ( Gan, Y; He, C; Huang, W; Lou, G; Meng, Z; Ness, CV; Wang, X; Wu, J; Xu, R; Yu, H; Zhang, Y; Zhou, H, 2012) |
| "The F2 rats which carried renal cell carcinoma were shown to possess the incidence of homozygosity of the LEC allele which is higher than that of the other genotypes at SSLP markers on chromosome 5 (chi2 = 17." | 1.30 | Identification of a locus for susceptibility to renal cell carcinoma in the Long-Evans Cinnamon rat. ( Hino, A; Izumi, K; Matsumoto, K; Sasaki, Y; Wei, K; Wei, S; Yamada, T, 1999) |
| " Strain variations among male mice were studied in terms of the number of days of survival with chronic administration of N-nitroso-diethylamine (NDEA)." | 1.28 | Mouse and rat strain variations in sensitivity to N-nitroso-diethylamine, hereditary transmission of the trait and the effect of 3-tert-butyl-4-hydroxyanisole on sensitivity. ( Horie, S; Ohbu, M; Okudaira, M, 1992) |
| "The R16 males developed liver cancer and the R16 females developed breast cancer, there also were malignancies in other organs in some animals." | 1.28 | Genetic control of susceptibility to diethylnitrosamine and dimethylbenzanthracene carcinogenesis in rats. ( Gill, TJ; Kunz, HW; Melhem, MF, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 10 (45.45) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Landerer, S | 1 |
| Kalthoff, S | 1 |
| Paulusch, S | 1 |
| Strassburg, CP | 1 |
| P Katare, D | 1 |
| Malik, S | 1 |
| J Mani, R | 1 |
| Ranjpour, M | 1 |
| Jain, SK | 1 |
| Liu, C | 1 |
| Ren, YF | 1 |
| Dong, J | 1 |
| Ke, MY | 1 |
| Ma, F | 1 |
| Monga, SPS | 1 |
| Wu, R | 1 |
| Lv, Y | 1 |
| Zhang, XF | 1 |
| Chen, S | 1 |
| Zheng, P | 1 |
| Wang, W | 1 |
| Yi, M | 1 |
| Chen, P | 1 |
| Cai, J | 1 |
| Li, J | 1 |
| Peng, Q | 1 |
| Ban, Y | 1 |
| Zhou, Y | 2 |
| Zeng, Z | 1 |
| Li, X | 1 |
| Xiong, W | 1 |
| Li, G | 1 |
| Xiang, B | 1 |
| Wang, J | 2 |
| Zhao, J | 1 |
| Chu, ES | 1 |
| Mok, MT | 1 |
| Go, MY | 1 |
| Man, K | 1 |
| Heuchel, R | 1 |
| Lan, HY | 1 |
| Chang, Z | 1 |
| Sung, JJ | 1 |
| Yu, J | 1 |
| Rajasekaran, D | 1 |
| Siddiq, A | 1 |
| Willoughby, JL | 1 |
| Biagi, JM | 1 |
| Christadore, LM | 1 |
| Yunes, SA | 1 |
| Gredler, R | 1 |
| Jariwala, N | 1 |
| Robertson, CL | 1 |
| Akiel, MA | 1 |
| Shen, XN | 1 |
| Subler, MA | 1 |
| Windle, JJ | 1 |
| Schaus, SE | 1 |
| Fisher, PB | 1 |
| Hansen, U | 1 |
| Sarkar, D | 1 |
| Mu, X | 1 |
| Pradere, JP | 1 |
| Affò, S | 1 |
| Dapito, DH | 1 |
| Friedman, R | 1 |
| Lefkovitch, JH | 1 |
| Schwabe, RF | 1 |
| Wei, T | 1 |
| Chen, W | 1 |
| Wen, L | 1 |
| Zhang, J | 1 |
| Zhang, Q | 1 |
| Yang, J | 1 |
| Liu, H | 1 |
| Chen, BW | 1 |
| Feng, X | 1 |
| Yang, Q | 1 |
| Bai, X | 1 |
| Liang, T | 1 |
| Qiu, B | 1 |
| Yu, Y | 1 |
| Zhen, C | 1 |
| Gu, J | 1 |
| Liu, W | 1 |
| Wen, Y | 1 |
| Chen, L | 1 |
| Gao, Y | 1 |
| Xia, Q | 1 |
| Kong, X | 1 |
| Ellis, JM | 1 |
| Paul, DS | 1 |
| Depetrillo, MA | 1 |
| Singh, BP | 1 |
| Malarkey, DE | 1 |
| Coleman, RA | 1 |
| Meng, Z | 1 |
| Wang, X | 1 |
| Gan, Y | 1 |
| Zhang, Y | 1 |
| Zhou, H | 1 |
| Ness, CV | 1 |
| Wu, J | 1 |
| Lou, G | 1 |
| Yu, H | 1 |
| He, C | 1 |
| Xu, R | 1 |
| Huang, W | 1 |
| De Miglio, MR | 2 |
| Pascale, RM | 2 |
| Simile, MM | 2 |
| Muroni, MR | 2 |
| Calvisi, DF | 1 |
| Virdis, P | 1 |
| Bosinco, GM | 1 |
| Frau, M | 1 |
| Seddaiu, MA | 1 |
| Ladu, S | 1 |
| Feo, F | 2 |
| Zhu, H | 1 |
| Wang, Y | 1 |
| Chen, J | 1 |
| Cheng, G | 1 |
| Xue, J | 1 |
| Canzian, F | 1 |
| Calvisi, D | 1 |
| Romeo, G | 1 |
| Wei, K | 1 |
| Izumi, K | 1 |
| Hino, A | 1 |
| Wei, S | 1 |
| Sasaki, Y | 1 |
| Yamada, T | 1 |
| Matsumoto, K | 1 |
| Tsukamoto, T | 1 |
| Inada, K | 1 |
| Fukami, H | 1 |
| Yamamoto, M | 1 |
| Tanaka, H | 1 |
| Kusakabe, M | 1 |
| Bishop, CE | 1 |
| Tatematsu, M | 1 |
| Im, YH | 1 |
| Kim, HT | 1 |
| Kim, IY | 1 |
| Factor, VM | 1 |
| Hahm, KB | 1 |
| Anzano, M | 1 |
| Jang, JJ | 1 |
| Flanders, K | 1 |
| Haines, DC | 1 |
| Thorgeirsson, SS | 1 |
| Sizeland, A | 1 |
| Kim, SJ | 1 |
| Bugni, JM | 1 |
| Poole, TM | 1 |
| Drinkwater, NR | 2 |
| Lee, GH | 1 |
| Horie, S | 1 |
| Ohbu, M | 1 |
| Okudaira, M | 1 |
| Melhem, MF | 1 |
| Kunz, HW | 1 |
| Gill, TJ | 1 |
| Buchmann, A | 1 |
| Bauer-Hofmann, R | 1 |
| Mahr, J | 1 |
| Luz, A | 1 |
| Schwarz, M | 1 |
1 review available for diethylnitrosamine and Genetic Predisposition
| Article | Year |
|---|---|
[Genetic control of hepatocarcinogenesis in mice].
Topics: Animals; Carcinogens; Diethylnitrosamine; Gene Expression Regulation; Genetic Predisposition to Dise | 2001 |
21 other studies available for diethylnitrosamine and Genetic Predisposition
| Article | Year |
|---|---|
UDP-glucuronosyltransferase polymorphisms affect diethylnitrosamine-induced carcinogenesis in humanized transgenic mice.
Topics: Animals; Biopsy; Carcinogenesis; Diethylnitrosamine; Disease Models, Animal; Enzyme Activation; Fema | 2020 |
Novel mutations in transthyretin gene associated with hepatocellular carcinoma.
Topics: 2-Acetylaminofluorene; Amino Acid Sequence; Animals; Apolipoprotein A-I; Biomarkers, Tumor; Carcinom | 2018 |
Activation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cyclin D1; Diethylnitrosamine; | 2017 |
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
Topics: Animals; Arginase; beta-N-Acetylhexosaminidases; Carcinoma, Hepatocellular; Diethylnitrosamine; Fema | 2018 |
Inhibitory role of Smad7 in hepatocarcinogenesis in mice and in vitro.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Cell Cycle Proteins; C | 2013 |
Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzodioxoles; Carcinoma, Hepatocellular; Cell Cycle Chec | 2015 |
Epithelial Transforming Growth Factor-β Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; | 2016 |
G protein-coupled estrogen receptor deficiency accelerates liver tumorigenesis by enhancing inflammation and fibrosis.
Topics: Animals; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Diethylnitrosamine | 2016 |
DJ-1 promotes development of DEN-induced hepatocellular carcinoma and proliferation of liver cancer cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Diethylnitrosamine; Geneti | 2017 |
Mice deficient in glycerol-3-phosphate acyltransferase-1 have a reduced susceptibility to liver cancer.
Topics: Animals; Cell Proliferation; Diethylnitrosamine; Genetic Predisposition to Disease; Glycerol-3-Phosp | 2012 |
Deletion of IFNγ enhances hepatocarcinogenesis in FXR knockout mice.
Topics: Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Models, Animal; Gene Deletion; Genet | 2012 |
Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis.
Topics: Animals; Carcinogens; Chromosome Mapping; Crosses, Genetic; Diethylnitrosamine; Female; Genetic Link | 2002 |
Transgenic mice expressing hepatitis B virus X protein are more susceptible to carcinogen induced hepatocarcinogenesis.
Topics: Adenoma, Liver Cell; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma, Hepatocellular; Diethyl | 2004 |
Identification of genetic loci controlling hepatocarcinogenesis on rat chromosomes 7 and 10.
Topics: Animals; Carcinogens; Chromosome Mapping; Crosses, Genetic; Diethylnitrosamine; Female; Genetic Mark | 1999 |
Identification of a locus for susceptibility to renal cell carcinoma in the Long-Evans Cinnamon rat.
Topics: Alkylating Agents; Animals; Carcinoma, Renal Cell; Chromosome Mapping; Crosses, Genetic; Diethylnitr | 1999 |
Mouse strain susceptibility to diethylnitrosamine induced hepatocarcinogenesis is cell autonomous whereas sex-susceptibility Is due to the micro-environment: analysis with C3H <--> BALB / c sexually chimeric mice.
Topics: Animals; Antibodies; Carcinogens; Chimera; Cocarcinogenesis; Diethylnitrosamine; Female; Genetic Mar | 2000 |
Heterozygous mice for the transforming growth factor-beta type II receptor gene have increased susceptibility to hepatocellular carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Female; Gene Dosage; Gene | 2001 |
The little mutation suppresses DEN-induced hepatocarcinogenesis in mice and abrogates genetic and hormonal modulation of susceptibility.
Topics: Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Hepatocellular; Diethylnitrosamine; Female; Gene | 2001 |
Mouse and rat strain variations in sensitivity to N-nitroso-diethylamine, hereditary transmission of the trait and the effect of 3-tert-butyl-4-hydroxyanisole on sensitivity.
Topics: Animals; Anticarcinogenic Agents; Butylated Hydroxyanisole; Cytochrome P-450 Enzyme System; Diethyln | 1992 |
Genetic control of susceptibility to diethylnitrosamine and dimethylbenzanthracene carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diethylnitrosamine; Female; Genetic Predisposition to Dis | 1991 |
Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis.
Topics: Animals; Base Sequence; Codon; Diethylnitrosamine; Ethylnitrosourea; Gene Expression Regulation, Neo | 1991 |