diethylnitrosamine has been researched along with Cirrhoses, Experimental Liver in 32 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we describe steps to establish liver cancer in a rat model, via chronic administration of diethylnitrosamine." | 1.62 | Optimized protocol for an inducible rat model of liver tumor with chronic hepatocellular injury, inflammation, fibrosis, and cirrhosis. ( Chen, Z; Han, L; He, X; Li, S, 2021) |
| "Diethylnitrosamine (DEN) was used to induce pre-carcinoma and early HCC nodules in the experimental group." | 1.43 | Detection and differentiation of early hepatocellular carcinoma from cirrhosis using CT perfusion in a rat liver model. ( Feng, GL; Jiang, HJ; Li, DQ; Li, JP; Wan, Y; Wang, HB; Zhao, DL, 2016) |
| "Diethylnitrosamine (DEN) was administered to rats as a single dose, which is known not to give rise to liver tumours without subsequent promotion." | 1.30 | Iron promotes DEN initiated GST-P foci in rat liver. ( Carthew, P; Edwards, RE; Nolan, BM; Smith, AG, 1997) |
| " In conclusion, chronic administration of thioacetamide at low doses provided strong promoting stimuli for previously initiated hepatocytes." | 1.28 | Chronic liver injury by thioacetamide and promotion of hepatic carcinogenesis. ( Gervasi, PG; Longo, V; Malvaldi, G; Marzano, M; Saviozzi, M, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (15.63) | 18.7374 |
| 1990's | 10 (31.25) | 18.2507 |
| 2000's | 4 (12.50) | 29.6817 |
| 2010's | 12 (37.50) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Z | 1 |
| Li, S | 1 |
| Han, L | 1 |
| He, X | 1 |
| Reebye, V | 1 |
| Huang, KW | 1 |
| Lin, V | 1 |
| Jarvis, S | 1 |
| Cutilas, P | 1 |
| Dorman, S | 1 |
| Ciriello, S | 1 |
| Andrikakou, P | 1 |
| Voutila, J | 1 |
| Saetrom, P | 1 |
| Mintz, PJ | 1 |
| Reccia, I | 1 |
| Rossi, JJ | 1 |
| Huber, H | 1 |
| Habib, R | 1 |
| Kostomitsopoulos, N | 1 |
| Blakey, DC | 1 |
| Habib, NA | 1 |
| Lee, C | 1 |
| Kim, M | 1 |
| Lee, JH | 1 |
| Oh, J | 1 |
| Shin, HH | 1 |
| Lee, SM | 1 |
| Scherer, PE | 1 |
| Kwon, HM | 1 |
| Choi, JH | 1 |
| Park, J | 1 |
| Man, S | 1 |
| Fan, W | 1 |
| Gao, W | 1 |
| Li, Y | 1 |
| Wang, Y | 1 |
| Liu, Z | 1 |
| Li, H | 1 |
| Cha, JH | 1 |
| Bae, SH | 1 |
| Kim, HL | 1 |
| Park, NR | 1 |
| Choi, ES | 1 |
| Jung, ES | 1 |
| Choi, JY | 1 |
| Yoon, SK | 1 |
| MadanKumar, P | 1 |
| NaveenKumar, P | 1 |
| Manikandan, S | 1 |
| Devaraj, H | 1 |
| NiranjaliDevaraj, S | 1 |
| Marrone, AK | 1 |
| Shpyleva, S | 1 |
| Chappell, G | 1 |
| Tryndyak, V | 1 |
| Uehara, T | 1 |
| Tsuchiya, M | 1 |
| Beland, FA | 1 |
| Rusyn, I | 1 |
| Pogribny, IP | 1 |
| Mu, X | 2 |
| Español-Suñer, R | 1 |
| Mederacke, I | 1 |
| Affò, S | 2 |
| Manco, R | 1 |
| Sempoux, C | 1 |
| Lemaigre, FP | 1 |
| Adili, A | 1 |
| Yuan, D | 1 |
| Weber, A | 1 |
| Unger, K | 1 |
| Heikenwälder, M | 1 |
| Leclercq, IA | 1 |
| Schwabe, RF | 2 |
| Pradere, JP | 1 |
| Dapito, DH | 1 |
| Friedman, R | 1 |
| Lefkovitch, JH | 1 |
| Wei, T | 1 |
| Chen, W | 1 |
| Wen, L | 1 |
| Zhang, J | 1 |
| Zhang, Q | 1 |
| Yang, J | 1 |
| Liu, H | 1 |
| Chen, BW | 1 |
| Zhou, Y | 1 |
| Feng, X | 1 |
| Yang, Q | 1 |
| Bai, X | 1 |
| Liang, T | 1 |
| Liang, L | 1 |
| Yang, X | 1 |
| Yu, Y | 1 |
| Li, X | 1 |
| Wu, Y | 1 |
| Shi, R | 1 |
| Jiang, J | 1 |
| Gao, L | 1 |
| Ye, F | 1 |
| Zhao, Q | 1 |
| Li, R | 1 |
| Wei, L | 1 |
| Han, Z | 1 |
| Li, JP | 1 |
| Feng, GL | 1 |
| Li, DQ | 1 |
| Wang, HB | 1 |
| Zhao, DL | 1 |
| Wan, Y | 1 |
| Jiang, HJ | 1 |
| Maeda, M | 1 |
| Takami, T | 1 |
| Terai, S | 1 |
| Sakaida, I | 1 |
| SCHMAEHL, D | 1 |
| THOMAS, C | 1 |
| SATTLER, W | 1 |
| Tessitore, L | 1 |
| Bollito, E | 1 |
| Bozova, S | 1 |
| Elpek, GO | 1 |
| de Heer, K | 1 |
| Sauer, HD | 1 |
| Klöppel, G | 1 |
| Xu, X | 1 |
| Ruan, YB | 1 |
| Wu, ZB | 1 |
| Zalatnai, A | 7 |
| Lapis, K | 6 |
| Uchida, M | 1 |
| Hamura, H | 1 |
| Takagi, S | 1 |
| Noguchi, Y | 1 |
| Shibata, H | 1 |
| Honda, H | 1 |
| Cho, KJ | 1 |
| Jang, JJ | 1 |
| Timár, F | 1 |
| Thorgeirsson, UP | 1 |
| Carthew, P | 1 |
| Nolan, BM | 1 |
| Smith, AG | 1 |
| Edwards, RE | 1 |
| Murakami, S | 1 |
| Ohnishi, A | 1 |
| Matsuo, A | 1 |
| Kawai, B | 1 |
| Tada, T | 1 |
| Kunihiro, N | 1 |
| Chau, T | 1 |
| Nagayama, K | 1 |
| Tanaka, T | 1 |
| Lakatos, PL | 1 |
| Firneisz, G | 1 |
| Borcsiczky, D | 1 |
| Selmeci, L | 1 |
| Szalay, F | 1 |
| Corpechot, C | 1 |
| Barbu, V | 1 |
| Wendum, D | 1 |
| Kinnman, N | 1 |
| Rey, C | 1 |
| Poupon, R | 1 |
| Housset, C | 1 |
| Rosmorduc, O | 1 |
| Kovalszky, I | 1 |
| Szeberenyi, S | 1 |
| Vincze, I | 1 |
| Jeney, A | 1 |
| Sárosi, I | 1 |
| Rot, A | 1 |
| Lapsis, K | 1 |
| Gervasi, PG | 1 |
| Longo, V | 1 |
| Marzano, M | 1 |
| Saviozzi, M | 1 |
| Malvaldi, G | 1 |
| Luo, DY | 1 |
| Wang, CJ | 1 |
| Deng, SL | 1 |
32 other studies available for diethylnitrosamine and Cirrhoses, Experimental Liver
| Article | Year |
|---|---|
Optimized protocol for an inducible rat model of liver tumor with chronic hepatocellular injury, inflammation, fibrosis, and cirrhosis.
Topics: Animals; Carcinogenesis; Diethylnitrosamine; Humans; Inflammation; Liver Cirrhosis, Experimental; Li | 2021 |
Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer.
Topics: Animals; CCAAT-Enhancer-Binding Proteins; Diethylnitrosamine; End Stage Liver Disease; Gene Expressi | 2018 |
COL6A3-derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver disease.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Communication; Chemical an | 2019 |
Anti-fibrosis and anti-cirrhosis effects of Rhizoma paridis saponins on diethylnitrosamine induced rats.
Topics: Animals; Diethylnitrosamine; DNA Fragmentation; Gene Expression Regulation; Liver Cirrhosis; Liver C | 2014 |
Branched-chain amino acids ameliorate fibrosis and suppress tumor growth in a rat model of hepatocellular carcinoma with liver cirrhosis.
Topics: Administration, Oral; Amino Acids, Branched-Chain; Animals; Anticarcinogenic Agents; Carcinogenesis; | 2013 |
Morin ameliorates chemically induced liver fibrosis in vivo and inhibits stellate cell proliferation in vitro by suppressing Wnt/β-catenin signaling.
Topics: Animals; beta Catenin; Cell Line; Cell Proliferation; Cell Survival; Cyclin D1; Cytoprotection; Diet | 2014 |
Differentially expressed MicroRNAs provide mechanistic insight into fibrosis-associated liver carcinogenesis in mice.
Topics: Animals; Carbon Tetrachloride; Cell Line, Tumor; Diethylnitrosamine; Gene Expression Profiling; Gene | 2016 |
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.
Topics: alpha-Fetoproteins; Animals; Bile Ducts; Biomarkers, Tumor; Carbon Tetrachloride; Carcinogens; Cell | 2015 |
Epithelial Transforming Growth Factor-β Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; | 2016 |
G protein-coupled estrogen receptor deficiency accelerates liver tumorigenesis by enhancing inflammation and fibrosis.
Topics: Animals; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Diethylnitrosamine | 2016 |
Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway.
Topics: Animals; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cyclin D1; Cytokines; Cytoprote | 2016 |
Detection and differentiation of early hepatocellular carcinoma from cirrhosis using CT perfusion in a rat liver model.
Topics: Animals; Area Under Curve; Blood Flow Velocity; Capillary Permeability; Carcinoma, Hepatocellular; C | 2016 |
Autologous bone marrow cell infusions suppress tumor initiation in hepatocarcinogenic mice with liver cirrhosis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Bone Marrow Transplantation; Carbon Tetrachloride; Carcinoma, | 2012 |
[HEPATOTOXIC AND CIRRHOGENIC EFFECT OF DIETHYLNITROSAMINE IN DOGS].
Topics: Chemical and Drug Induced Liver Injury; Diethylnitrosamine; Dogs; Gastrointestinal Diseases; Hepatit | 1964 |
Early induction of TGF-beta1 through a fasting-re-feeding regimen promotes liver carcinogenesis by a sub-initiating dose of diethylnitrosamine.
Topics: 2-Acetylaminofluorene; Animals; Apoptosis; bcl-2-Associated X Protein; Carbon Tetrachloride; Carcino | 2006 |
Hypoxia-inducible factor-1alpha expression in experimental cirrhosis: correlation with vascular endothelial growth factor expression and angiogenesis.
Topics: Alkylating Agents; Animals; Diethylnitrosamine; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Li | 2007 |
[Protective effect of cholestyramine in the hepatocarcinogenesis of the rat (author's transl)].
Topics: Animals; Bile Acids and Salts; Cholestyramine Resin; Diethylnitrosamine; Liver Cirrhosis, Experiment | 1981 |
Study on the role of mast cells in the development of liver fibrosis during diethylnitrosamine (DEN) -induced hepatocarcinogenesis in rats.
Topics: Animals; Diethylnitrosamine; Fibroblasts; Hyperplasia; Liver; Liver Cirrhosis, Experimental; Male; M | 1994 |
Simultaneous induction of liver cirrhosis and hepatocellular carcinomas in F-344 rats: establishment of a short hepatocarcinogenesis model.
Topics: Animals; Carbon Tetrachloride; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Hepatectomy; | 1994 |
[Acidified aspirin-induced gastric lesion in rats with hepatic cirrhosis produced by N-nitrosodiethylamine or carbon tetrachloride. Effect of aldioxa on gastric lesions].
Topics: Allantoin; Aluminum Hydroxide; Animals; Antacids; Aspirin; Carbon Tetrachloride; Diethylnitrosamine; | 1994 |
Decreased hepatocarcinogenic effect of diethylnitrosamine in experimentally induced liver cirrhosis in rat: delay or inhibition?
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Diethylnitrosamine; Liver; Liver Cirr | 1994 |
Effects of carbon tetrachloride, ethanol and acetaldehyde on diethylnitrosamine-induced hepatocarcinogenesis in rats.
Topics: Acetaldehyde; Animals; Animals, Newborn; Body Weight; Carbon Tetrachloride; Diethylnitrosamine; Etha | 1993 |
Quantitative evaluation of lysozyme- and CD68-positive Kupffer cells in diethylnitrosamine-induced hepatocellular carcinomas in monkeys.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Carcinogens; Diethylnitrosamine; I | 1995 |
Iron promotes DEN initiated GST-P foci in rat liver.
Topics: Animals; Biomarkers; Body Weight; Carcinogens; Chemical and Drug Induced Liver Injury; Diethylnitros | 1997 |
Hepatic denervation ameliorates sodium and water retention in experimental cirrhosis in rats.
Topics: Animals; Diethylnitrosamine; Disease Models, Animal; Evaluation Studies as Topic; Homeostasis; Kidne | 1997 |
Elevated serum dipeptidyl peptidase IV (CD26, EC 3.4.14.5) activity in experimental liver cirrhosis.
Topics: Animals; Diethylnitrosamine; Dipeptidyl Peptidase 4; Liver Cirrhosis, Experimental; Male; Rats; Rats | 2000 |
Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis.
Topics: Alkylating Agents; Animals; Cells, Cultured; Collagen Type I; Collagen Type IV; Diethylnitrosamine; | 2002 |
Modification of DENA-induced hepatocarcinogenesis by CCl4 cirrhosis. Comparison of the marker enzyme patterns.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Drug Administrati | 1992 |
Inhibitory and promoting effects of carbon tetrachloride-induced liver cirrhosis on the diethylnitrosamine hepatocarcinogenesis in rats.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Diethylnitrosamine; Liver; Liver Cirr | 1991 |
Chronic liver injury by thioacetamide and promotion of hepatic carcinogenesis.
Topics: Acetamides; Animals; Carcinogens; Diethylnitrosamine; Liver; Liver Cirrhosis, Experimental; Liver Ne | 1989 |
Diethyl-nitrosamine hepatocarcinogenesis in cirrhotic rats.
Topics: Animals; Carbon Tetrachloride; Diethylnitrosamine; Liver Cirrhosis, Experimental; Liver Neoplasms, E | 1987 |
[Effect of subtotal hepatectomy in rats on the induction of cirrhosis of liver and hepatocellular carcinoma by diethylnitrosamine].
Topics: Animals; Diethylnitrosamine; Female; Hepatectomy; Liver Cirrhosis, Experimental; Liver Neoplasms, Ex | 1987 |