diethylnitrosamine has been researched along with Chromosomal Instability in 4 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chromosomal Instability: An increased tendency to acquire CHROMOSOME ABERRATIONS when various processes involved in chromosome replication, repair, or segregation are dysfunctional.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chromosomal instability is a characteristic feature of hepatocellular carcinoma (HCC) but its origin and role in liver carcinogenesis are undefined." | 1.35 | Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice. ( Dan, YY; Fausto, N; Gu, Y; Haque, J; Lehman, S; Swisshelm, K; Teoh, NC; Wright, JH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kay, JE | 1 |
| Corrigan, JJ | 1 |
| Armijo, AL | 1 |
| Nazari, IS | 1 |
| Kohale, IN | 1 |
| Torous, DK | 1 |
| Avlasevich, SL | 1 |
| Croy, RG | 1 |
| Wadduwage, DN | 1 |
| Carrasco, SE | 1 |
| Dertinger, SD | 1 |
| White, FM | 1 |
| Essigmann, JM | 1 |
| Samson, LD | 1 |
| Engelward, BP | 1 |
| Carloni, V | 1 |
| Lulli, M | 1 |
| Madiai, S | 1 |
| Mello, T | 1 |
| Hall, A | 1 |
| Luong, TV | 1 |
| Pinzani, M | 1 |
| Rombouts, K | 1 |
| Galli, A | 1 |
| Teoh, NC | 1 |
| Dan, YY | 1 |
| Swisshelm, K | 1 |
| Lehman, S | 1 |
| Wright, JH | 1 |
| Haque, J | 1 |
| Gu, Y | 1 |
| Fausto, N | 1 |
| Mayhew, CN | 1 |
| Carter, SL | 1 |
| Fox, SR | 1 |
| Sexton, CR | 1 |
| Reed, CA | 1 |
| Srinivasan, SV | 1 |
| Liu, X | 1 |
| Wikenheiser-Brokamp, K | 1 |
| Boivin, GP | 1 |
| Lee, JS | 1 |
| Aronow, BJ | 1 |
| Thorgeirsson, SS | 1 |
| Knudsen, ES | 1 |
4 other studies available for diethylnitrosamine and Chromosomal Instability
| Article | Year |
|---|---|
Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice.
Topics: Animals; Biomarkers, Tumor; Cell Death; Chromosomal Instability; Diethylnitrosamine; Disease Suscept | 2021 |
CHK2 overexpression and mislocalisation within mitotic structures enhances chromosomal instability and hepatocellular carcinoma progression.
Topics: Animals; Aurora Kinase B; Biological Transport; Carcinogens; Carcinoma, Hepatocellular; Cell Nucleus | 2018 |
Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice.
Topics: Actins; Animals; Antigens, Nuclear; Aurora Kinase A; Aurora Kinases; Carcinogens; Carcinoma, Hepatoc | 2008 |
RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Cycle; Chromosomal Instability; Diethylnitrosamine; Disease | 2007 |