diethylnitrosamine has been researched along with Cholestasis in 5 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We studied mice with bile-duct ligation, orthotopic cholangiocarcinomas, cholestasis-induced cholangiocarcinoma, diethylnitrosamine-induced liver tumors, and xenograft tumors." | 3.88 | Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer. ( Annamalai, A; Fan, W; Li, TWH; Liu, T; Liu, Z; Lu, SC; Maldonado, SS; Mato, JM; Noureddin, M; Seki, E; Shen, H; Steggerda, J; Tu, J; Wang, J; Xiong, T; Yang, H; Yang, J, 2018) |
| "To induce chronic cholestasis, Balb/c mice were given 2 weekly intraperitoneal injections of diethylnitrosamine (DEN); 2 weeks later, some mice also received left and median bile duct ligation (LMBDL) and, then 1 week later, were fed DEN, in corn oil, weekly by oral gavage (DLD)." | 3.77 | A mouse model of cholestasis-associated cholangiocarcinoma and transcription factors involved in progression. ( Aller, MA; Ko, KS; Li, TW; Peng, J; Tang, X; Xia, M; Yang, H, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, T | 1 |
| Yang, H | 2 |
| Fan, W | 1 |
| Tu, J | 1 |
| Li, TWH | 1 |
| Wang, J | 1 |
| Shen, H | 1 |
| Yang, J | 1 |
| Xiong, T | 1 |
| Steggerda, J | 1 |
| Liu, Z | 1 |
| Noureddin, M | 1 |
| Maldonado, SS | 1 |
| Annamalai, A | 1 |
| Seki, E | 1 |
| Mato, JM | 1 |
| Lu, SC | 1 |
| Zhou, L | 1 |
| Pradhan-Sundd, T | 1 |
| Poddar, M | 1 |
| Singh, S | 1 |
| Kikuchi, A | 1 |
| Stolz, DB | 1 |
| Shou, W | 1 |
| Li, Z | 1 |
| Nejak-Bowen, KN | 1 |
| Monga, SP | 1 |
| Vatakuti, S | 1 |
| Pennings, JL | 1 |
| Gore, E | 1 |
| Olinga, P | 1 |
| Groothuis, GM | 1 |
| Lai, KKY | 1 |
| Kweon, SM | 1 |
| Chi, F | 1 |
| Hwang, E | 1 |
| Kabe, Y | 1 |
| Higashiyama, R | 1 |
| Qin, L | 1 |
| Yan, R | 1 |
| Wu, RP | 1 |
| Lai, K | 1 |
| Fujii, N | 1 |
| French, S | 1 |
| Xu, J | 1 |
| Wang, JY | 1 |
| Murali, R | 1 |
| Mishra, L | 1 |
| Lee, JS | 1 |
| Ntambi, JM | 1 |
| Tsukamoto, H | 1 |
| Li, TW | 1 |
| Peng, J | 1 |
| Tang, X | 1 |
| Ko, KS | 1 |
| Xia, M | 1 |
| Aller, MA | 1 |
5 other studies available for diethylnitrosamine and Cholestasis
| Article | Year |
|---|---|
Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer.
Topics: Animals; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholangiocarcinoma; Chole | 2018 |
Mice with Hepatic Loss of the Desmosomal Protein γ-Catenin Are Prone to Cholestatic Injury and Chemical Carcinogenesis.
Topics: Animals; beta Catenin; Bile Ducts; Cell Transformation, Neoplastic; Cholestasis; Desmosomes; Diethyl | 2015 |
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.
Topics: Acetaminophen; Aged; Benzofurans; Bile Acids and Salts; Chloramphenicol; Chlorpromazine; Cholestasis | 2016 |
Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.
Topics: Animals; beta Catenin; beta Karyopherins; Carcinoma, Hepatocellular; Case-Control Studies; Cell Line | 2017 |
A mouse model of cholestasis-associated cholangiocarcinoma and transcription factors involved in progression.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Basic Helix-Loop-Helix Transcr | 2011 |