diethylnitrosamine has been researched along with Cell Transformation, Neoplastic in 218 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Placental growth factor (PlGF) inhibition produced promising results in reducing tumor burden in a diethylnitrosamine (DEN)-induced mouse model for hepatocellular carcinoma (HCC)." | 7.79 | Serum protein N-glycan alterations of diethylnitrosamine-induced hepatocellular carcinoma mice and their evolution after inhibition of the placental growth factor. ( Blomme, B; Colle, I; Geerts, A; Heindryckx, F; Stassen, JM; Van Vlierberghe, H, 2013) |
| "Cimetidine is known to have an anti-tumor effect on certain types of malignancies, though on hepatocellular carcinomas (HCCs), its effect remains unclear." | 7.74 | Anti-tumor effects of cimetidine on hepatocellular carcinomas in diethylnitrosamine-treated rats. ( Adachi, K; Amano, Y; Furuta, K; Ishihara, S; Ishine, J; Kinoshita, Y; Miyake, T; Okamoto, E; Sato, S, 2008) |
| " Here, hyperpolyploidization of hepatocytes around the centrilobular (CL) region is demonstrated to be closely linked with the development of HCC cells after diethylnitrosamine treatment." | 4.02 | Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver. ( Chao, HW; Chen, H; Chen, HW; Doi, M; Fustin, JM; Hou, HS; Huang, YS; King, PC; Lai, HH; Lee, YL; Lin, H; Lin, SH; Young, PY, 2021) |
| " Treatment with 2500 ppm ACI for 26 weeks after initiation with diethylnitrosamine increased the incidence and multiplicities of altered foci and adenomas in hepatocytes from WT mice; these effects were significantly reduced in CARKO mice." | 3.83 | Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development. ( Ichimura, R; Inoue, K; Kodama, Y; Kuwata, K; Shibutani, M; Takahashi, M; Yoshida, M, 2016) |
| " Maid levels were also high in hepatic preneoplastic foci induced by treatment of zebrafish with diethylnitrosamine (DEN), but low in hepatocellular carcinomas (HCC), mixed tumors, and cholangiocarcinomas developing in these animals." | 3.81 | Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging. ( Fujisawa, K; Furutani-Seiki, M; Matsumoto, T; Nishina, H; Sakaida, I; Takami, T; Terai, S; Yamamoto, N, 2015) |
| "Placental growth factor (PlGF) inhibition produced promising results in reducing tumor burden in a diethylnitrosamine (DEN)-induced mouse model for hepatocellular carcinoma (HCC)." | 3.79 | Serum protein N-glycan alterations of diethylnitrosamine-induced hepatocellular carcinoma mice and their evolution after inhibition of the placental growth factor. ( Blomme, B; Colle, I; Geerts, A; Heindryckx, F; Stassen, JM; Van Vlierberghe, H, 2013) |
| " In the present study, we showed that MAP1S levels immediately become elevated in response to diethylnitrosamine-induced or genome instability-driven metabolic stress in a murine model of hepatocarcinoma." | 3.77 | Autophagy enhanced by microtubule- and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis. ( Liu, L; McKeehan, WL; Wang, F; Xie, R, 2011) |
| "Cimetidine is known to have an anti-tumor effect on certain types of malignancies, though on hepatocellular carcinomas (HCCs), its effect remains unclear." | 3.74 | Anti-tumor effects of cimetidine on hepatocellular carcinomas in diethylnitrosamine-treated rats. ( Adachi, K; Amano, Y; Furuta, K; Ishihara, S; Ishine, J; Kinoshita, Y; Miyake, T; Okamoto, E; Sato, S, 2008) |
| "Formation and repair of O6-medG and N7-medG (O6- and N7-methyldeoxyguanosine) in glutathione S-transferase-P form (GST-P)-positive liver cell foci, nodules, primary hepatocellular carcinoma (HCC) and transplanted hepatocellular carcinoma (TRP) induced by N-ethyl-N-hydroxyethylnitrosamine (EHEN) were immunohistochemically assessed following a single exposure to dimethylnitrosamine (DMN)." | 3.68 | Decreased dimethylnitrosamine-induced O6- and N7-methyldeoxyguanosine levels correlate with development and progression of lesions in rat hepatocarcinogenesis. ( Asamoto, M; Iwase, T; Kato, T; Matsumoto, K; Montesano, R; Nagao, S; Ozaki, K; Tsuda, H; Wild, CP, 1993) |
| " The animal models were Sewall Wright strain 13 guinea pigs with 3-methyl-cholanthrene (MCA)-induced fibrosarcomas and strain 2 guinea pigs with diethylnitrosamine (DEN)-induced hepatocarcinomas." | 3.66 | Guinea pig cell-mediated tumor immunity: the chromium release assay detects both cytolysis and serum blocking for syngeneic chemically-induced tumors. ( Blazkovec, AA; Miller, FR, 1979) |
| "05% in the diet) for 6 months following a single dose of diethylnitrosamine (5 to 10 mg/kg) given within 24 hours after partial hepatectomy resulted in a marked increase in the number of enzyme-altered foci in the liver as well as in the production of hepatocellular carcinomas." | 3.65 | The natural history of neoplasia. Newer insights into an old problem. ( Pitot, HC, 1977) |
| " Examples are shown, illustrating that the current practice of labeling dose-response curves for carcinogenesis as supralinear, linear or sublinear, is meaningless unless the dose-response scales are defined." | 2.43 | Critique of dose response in carcinogenesis. ( Waddell, WJ, 2006) |
| "Hepatocellular carcinoma is a common primary malignancy of hepatocytes that has caused many fatalities globally." | 1.48 | Inhibitory effects of mushroom extracts on progression of carcinogenesis in mice. ( Omwandho, C; Wasonga, C, 2018) |
| "Human hepatocellular carcinomas (HCCs), which arise on a background of chronic liver damage and inflammation, express c-Fos, a component of the AP-1 transcription factor." | 1.46 | Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation. ( Bakiri, L; Campos-Olivas, R; Dienes, HP; Graña, O; Guío-Carrión, A; Hamacher, R; Hasenfuss, SC; Martinez, L; Thomsen, MK; Wagner, EF, 2017) |
| "Dieckol (DEK) is a major polyphenol of marine brown seaweed Ecklonia cava which is a potential candidate for cancer therapy." | 1.46 | Modulatory efficacy of dieckol on xenobiotic-metabolizing enzymes, cell proliferation, apoptosis, invasion and angiogenesis during NDEA-induced rat hepatocarcinogenesis. ( Duraikannu, A; Fredrick, WS; Gobalakrishnan, R; Kodisundaram, P; Ravichandran, S; Sadeeshkumar, V, 2017) |
| "Determining the origin of liver cancer stem cells is important for treating hepatocellular carcinoma." | 1.46 | Tg737 regulates epithelial-mesenchymal transition and cancer stem cell properties via a negative feedback circuit between Snail and HNF4α during liver stem cell malignant transformation. ( Bian, Z; Chen, C; Dai, B; Huang, Q; Liu, W; Pu, M; Qu, X; Shen, L; Tang, H; Tao, K; Zhao, G, 2017) |
| "While gender differences in hepatocellular carcinoma (HCC) are profound, the mechanism is unclear." | 1.43 | Testosterone regulation of cyclin E kinase: A key factor in determining gender differences in hepatocarcinogenesis. ( Barn, VA; Blackburn, AC; Board, P; Farrell, GC; Pok, S; Teoh, NC; Wong, HJ, 2016) |
| "Dieckol (DEK) is a naturally occuring phlorotannins found in marine brown algae Ecklonia cava which is attributed with various pharmacological properties." | 1.43 | Protective effects of dieckol on N-nitrosodiethylamine induced hepatocarcinogenesis in rats. ( Duraikannu, A; Fredrick, WS; Kodisundaram, P; Ravichandran, S; Sadeeshkumar, V; Sivaperumal, R, 2016) |
| "Experimentally induced hepatocellular carcinoma is considered one of the representative laboratory models for studying this process." | 1.42 | Dynamic metabolic change is indicative of inflammation-induced transformation of hepatic cells. ( Cai, JC; Cathopoulis, T; Han, R; Li, X; Liu, F; Liu, GY; Lu, K; Luo, G; Peng, B; Shi, SL; Yang, L, 2015) |
| "We found that loss of MnSOD in hepatoma cells contributed to their conversion toward a more malignant phenotype, affecting all cellular properties generally associated with metabolic transformation and tumorigenesis." | 1.42 | Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis. ( Dombrowski, F; Görlach, A; Jakupovic, M; Kietzmann, T; Konzack, A; Kubaichuk, K; Miinalainen, I; Sormunen, R, 2015) |
| "A mouse model of fibrosis-associated liver cancer that was designed to emulate cirrhotic liver, a prevailing disease state observed in most humans with HCC, was used." | 1.40 | Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice. ( Beland, FA; Chappell, G; Hoenerhoff, M; Hong, HH; Kutanzi, K; Pogribny, IP; Rusyn, I; Tryndyak, V; Uehara, T, 2014) |
| "Liver cirrhosis is a predominant risk factor for hepatocellular carcinoma (HCC)." | 1.38 | Hepatic transforming growth factor beta gives rise to tumor-initiating cells and promotes liver cancer development. ( Chen, C; Ding, J; Feng, GS; Han, T; Huang, L; Li, Z; Ning, BF; Sun, W; Wang, C; Wang, HY; Wen, W; Wu, K; Wu, MC; Xie, WF; Yang, W, 2012) |
| " Using this model, we investigated the efficacy of an equivalent dosage of dietary LY from either a pure compound or a tomato extract (TE) against NASH-promoted hepatocarcinogenesis." | 1.36 | Dietary lycopene and tomato extract supplementations inhibit nonalcoholic steatohepatitis-promoted hepatocarcinogenesis in rats. ( Ausman, LM; Greenberg, AS; Russell, RM; Wang, XD; Wang, Y, 2010) |
| "p53 Mutations are very common in human hepatocellular carcinoma, and induction of hepatic p53 expression causes lysis of implanted hepatoblastoma cells in a chimeric mouse." | 1.36 | Induction of p53 renders ATM-deficient mice refractory to hepatocarcinogenesis. ( Dan, YY; Farrell, G; Fausto, N; Gu, Y; Hou, J; Mitchell, C; Pyakurel, P; Swisshelm, K; Teoh, N, 2010) |
| "5 ppm vanadium is potentially and optimally effective, as derived from dose-response studies, in limiting early molecular events and preneoplastic lesions, thereby modulating the initiation stage of hepatocarcinogenesis." | 1.34 | Carcinogen-induced early molecular events and its implication in the initiation of chemical hepatocarcinogenesis in rats: chemopreventive role of vanadium on this process. ( Chakraborty, T; Chatterjee, A; Chatterjee, M; Dhachinamoorthi, D; Kumar P, A; Rana, A, 2007) |
| "Cyclohexanol is a basic industrial chemical widely used because of its versatility as an industrial solvent." | 1.34 | Co-carcinogenic effect of cyclohexanol on the development of preneoplastic lesions in a rat hepatocarcinogenesis model. ( Alemán-Lazarini, L; Arce-Popoca, E; Cabrales-Romero, Mdel P; Carrasco-Legleu, CE; Fatel-Fazenda, S; Márquez-Rosado, L; Sierra-Santoyo, A; Trejo-Solís, C; Villa-Treviño, S, 2007) |
| " Three weeks after DEN treatment, Fas-mediated liver cell apoptosis induced by anti-Fas antibody resulted in a biphasic effect on induction of liver cell tumours, depending on dosage and time of antibody administration." | 1.31 | Effects of Fas-mediated liver cell apoptosis on diethylnitrosamine-induced hepatocarcinogenesis in mice. ( Hara, A; Kawabata, K; Matsunaga, K; Mori, H; Sugie, S; Yamada, Y; Yoshimi, N, 2000) |
| "Aneuploidy was also present, as expected, in 4 of 33 AHF in the animals placed on CD + PHB." | 1.28 | Nuclear DNA content of altered hepatic foci in a rat liver carcinogenesis model. ( Cechner, RL; Hinrichsen, LI; Sudilovsky, O; Wang, JH; Whitacre, CM, 1990) |
| "The phenobarbital treatment became unnecessary when neoplastic nodules were present." | 1.27 | Promotion mechanism of phenobarbital and partial hepatectomy in DENA hepatocarcinogenesis cell kinetics effect. ( Barbason, H; Betz, EH; Rassenfosse, C, 1983) |
| " Therefore, we have begun to quantify the dose-response relationships for N-nitrosodiethylamine (NDEA)-induced hepatocarcinogenesis by characterizing the major promutagenic DNA adduct, O4-ethyldeoxythymidine (O4-etdT); hepatocyte proliferation; and hepatocyte initiation in rats continually exposed to drinking-water containing NDEA." | 1.27 | Molecular dosimetry of DNA alkylation during chronic exposure to carcinogens. ( Boucheron, JA; Deal, FH; Richardson, FC; Swenberg, JA; Tyeryar, LA, 1987) |
| "Diethylnitrosamine was used as initiating agent of hepatocarcinogenesis and lipid peroxidation levels were monitored in the homogenates from normal liver, hyperplastic nodules and tumour, incubated in the presence or in the absence of ascorbate or adenosine diphosphate-iron complex." | 1.27 | Resistance to oxidative stress by hyperplastic and neoplastic rat liver tissue monitored in terms of production of unpolar and medium polar carbonyls. ( Biasi, F; Biocca, ME; Canuto, RA; Cecchini, G; Chiarpotto, E; Dianzani, MU; Esterbauer, H; Muzio, G; Poli, G, 1986) |
| "Diethylnitrosamine failed to transform RLC-1 cells with or without tetradecanoylphorbol acetate (TPA) promotion." | 1.27 | 12-O-Tetradecanoylphorbol-13-acetate promotion of carcinogen-treated rat liver endothelial cells. ( Higgins, PJ, 1985) |
| " It was pointed out that the direct measurement of the dose-response relation (l(d) approximately dm) yields only the number of hits contributed by the carcinogen applied anose rate is low or very low, the contribution of background process becomes significant, and these hits contribute to the power of time, r, of the incidence-time relation." | 1.26 | Multi-hit kinetics of tumor formation, with special reference to experimental liver and human lung carcinogenesis and some gneral conclusions. ( Emmelot, P; Scherer, E, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 66 (30.28) | 18.7374 |
| 1990's | 27 (12.39) | 18.2507 |
| 2000's | 38 (17.43) | 29.6817 |
| 2010's | 84 (38.53) | 24.3611 |
| 2020's | 3 (1.38) | 2.80 |
| Authors | Studies |
|---|---|
| Chariyakornkul, A | 1 |
| Inboot, N | 1 |
| Taya, S | 2 |
| Wongpoomchai, R | 2 |
| Lin, H | 4 |
| Huang, YS | 1 |
| Fustin, JM | 1 |
| Doi, M | 1 |
| Chen, H | 1 |
| Lai, HH | 1 |
| Lin, SH | 1 |
| Lee, YL | 1 |
| King, PC | 1 |
| Hou, HS | 1 |
| Chen, HW | 1 |
| Young, PY | 1 |
| Chao, HW | 1 |
| Nozaki, Y | 1 |
| Hikita, H | 1 |
| Tanaka, S | 1 |
| Fukumoto, K | 1 |
| Urabe, M | 1 |
| Sato, K | 1 |
| Myojin, Y | 1 |
| Doi, A | 1 |
| Murai, K | 1 |
| Sakane, S | 1 |
| Saito, Y | 1 |
| Kodama, T | 1 |
| Sakamori, R | 1 |
| Tatsumi, T | 1 |
| Takehara, T | 1 |
| Bakiri, L | 1 |
| Hamacher, R | 1 |
| Graña, O | 1 |
| Guío-Carrión, A | 1 |
| Campos-Olivas, R | 1 |
| Martinez, L | 1 |
| Dienes, HP | 1 |
| Thomsen, MK | 1 |
| Hasenfuss, SC | 1 |
| Wagner, EF | 1 |
| Sadeeshkumar, V | 2 |
| Duraikannu, A | 2 |
| Ravichandran, S | 2 |
| Kodisundaram, P | 2 |
| Fredrick, WS | 2 |
| Gobalakrishnan, R | 1 |
| Pok, S | 3 |
| Vohra, H | 1 |
| Wehbe, C | 1 |
| Barn, VA | 2 |
| Arfianti, E | 1 |
| Dan, YY | 2 |
| Farrell, GC | 3 |
| Teoh, NC | 3 |
| Molina-Aguilar, C | 1 |
| Guerrero-Carrillo, MJ | 1 |
| Espinosa-Aguirre, JJ | 1 |
| Olguin-Reyes, S | 1 |
| Castro-Belio, T | 1 |
| Vázquez-Martínez, O | 1 |
| Rivera-Zavala, JB | 1 |
| Díaz-Muñoz, M | 1 |
| Huang, Q | 1 |
| Pu, M | 1 |
| Zhao, G | 1 |
| Dai, B | 1 |
| Bian, Z | 1 |
| Tang, H | 1 |
| Chen, C | 2 |
| Liu, W | 1 |
| Qu, X | 1 |
| Shen, L | 1 |
| Tao, K | 1 |
| Van, TM | 1 |
| Polykratis, A | 1 |
| Straub, BK | 1 |
| Kondylis, V | 1 |
| Papadopoulou, N | 1 |
| Pasparakis, M | 1 |
| Moreno-Marín, N | 1 |
| Barrasa, E | 1 |
| Morales-Hernández, A | 1 |
| Paniagua, B | 1 |
| Blanco-Fernández, G | 1 |
| Merino, JM | 1 |
| Fernández-Salguero, PM | 1 |
| Liu, C | 2 |
| Ren, YF | 1 |
| Dong, J | 1 |
| Ke, MY | 1 |
| Ma, F | 1 |
| Monga, SPS | 1 |
| Wu, R | 1 |
| Lv, Y | 1 |
| Zhang, XF | 1 |
| Shang, N | 1 |
| Bank, T | 1 |
| Ding, X | 1 |
| Breslin, P | 1 |
| Li, J | 2 |
| Shi, B | 1 |
| Qiu, W | 2 |
| Wasonga, C | 1 |
| Omwandho, C | 1 |
| Nishimura, N | 1 |
| Kaji, K | 1 |
| Kitade, M | 2 |
| Aihara, Y | 1 |
| Sato, S | 2 |
| Seki, K | 1 |
| Sawada, Y | 1 |
| Takaya, H | 1 |
| Okura, Y | 1 |
| Kawaratani, H | 1 |
| Moriya, K | 1 |
| Namisaki, T | 2 |
| Mitoro, A | 1 |
| Yoshiji, H | 2 |
| Ito, Y | 1 |
| Nakajima, K | 1 |
| Masubuchi, Y | 1 |
| Kikuchi, S | 1 |
| Saito, F | 1 |
| Akahori, Y | 1 |
| Jin, M | 1 |
| Yoshida, T | 1 |
| Shibutani, M | 2 |
| Cho, W | 1 |
| Jin, X | 1 |
| Pang, J | 1 |
| Wang, Y | 2 |
| Mivechi, NF | 2 |
| Moskophidis, D | 1 |
| Matboli, M | 1 |
| ElGwad, AA | 1 |
| Hasanin, AH | 1 |
| El-Tawdi, A | 1 |
| Habib, EK | 1 |
| Elmansy, RA | 1 |
| Ibrahim, D | 1 |
| Shehata, H | 1 |
| Tash, F | 1 |
| Moeini, A | 1 |
| Torrecilla, S | 1 |
| Tovar, V | 1 |
| Montironi, C | 1 |
| Andreu-Oller, C | 1 |
| Peix, J | 1 |
| Higuera, M | 1 |
| Pfister, D | 1 |
| Ramadori, P | 1 |
| Pinyol, R | 1 |
| Solé, M | 1 |
| Heikenwälder, M | 1 |
| Friedman, SL | 1 |
| Sia, D | 1 |
| Llovet, JM | 1 |
| Sun, K | 1 |
| Guo, XL | 1 |
| Zhao, QD | 1 |
| Jing, YY | 1 |
| Kou, XR | 1 |
| Xie, XQ | 1 |
| Zhou, Y | 2 |
| Cai, N | 1 |
| Gao, L | 1 |
| Zhao, X | 2 |
| Zhang, SS | 1 |
| Song, JR | 1 |
| Li, D | 1 |
| Deng, WJ | 1 |
| Li, R | 1 |
| Wu, MC | 2 |
| Wei, LX | 1 |
| Zhang, CL | 1 |
| Zeng, T | 2 |
| Zhao, XL | 1 |
| Xie, KQ | 1 |
| Dai, ZJ | 1 |
| Wu, WY | 1 |
| Kang, HF | 1 |
| Ma, XB | 2 |
| Zhang, SQ | 2 |
| Min, WL | 2 |
| Kang, WF | 1 |
| Lu, WF | 1 |
| Lin, S | 1 |
| Wang, XJ | 2 |
| Casper, M | 1 |
| Weber, SN | 1 |
| Kloor, M | 1 |
| Müllenbach, R | 1 |
| Grobholz, R | 1 |
| Lammert, F | 1 |
| Zimmer, V | 1 |
| Wen, V | 1 |
| Shackel, N | 1 |
| Alsop, A | 1 |
| Pyakurel, P | 2 |
| Fahrer, A | 1 |
| Yang, C | 1 |
| Lu, W | 1 |
| Lin, T | 1 |
| You, P | 1 |
| Ye, M | 1 |
| Huang, Y | 1 |
| Jiang, X | 1 |
| Wang, C | 2 |
| Wang, F | 3 |
| Lee, MH | 1 |
| Yeung, SC | 1 |
| Johnson, RL | 1 |
| Wei, C | 1 |
| Tsai, RY | 1 |
| Frazier, ML | 1 |
| McKeehan, WL | 3 |
| Luo, Y | 1 |
| Zhang, L | 2 |
| Zhao, R | 1 |
| Ye, SQ | 1 |
| Zhou, L | 2 |
| Wu, YN | 1 |
| Zeng, Y | 1 |
| Zhong, Q | 1 |
| Shi, G | 1 |
| Zhang, Q | 2 |
| Zhang, Y | 1 |
| Levy, D | 1 |
| Zhong, S | 1 |
| Papp, V | 1 |
| Rókusz, A | 1 |
| Dezső, K | 1 |
| Bugyik, E | 1 |
| Szabó, V | 1 |
| Pávai, Z | 1 |
| Paku, S | 1 |
| Nagy, P | 2 |
| Ip, BC | 1 |
| Hu, KQ | 1 |
| Smith, DE | 1 |
| Obin, MS | 1 |
| Ausman, LM | 2 |
| Wang, XD | 2 |
| Chappell, G | 1 |
| Kutanzi, K | 2 |
| Uehara, T | 2 |
| Tryndyak, V | 1 |
| Hong, HH | 1 |
| Hoenerhoff, M | 1 |
| Beland, FA | 1 |
| Rusyn, I | 2 |
| Pogribny, IP | 2 |
| Postnikov, YV | 1 |
| Furusawa, T | 1 |
| Haines, DC | 2 |
| Factor, VM | 2 |
| Bustin, M | 1 |
| Chen, L | 2 |
| Lu, X | 1 |
| Chen, Y | 1 |
| Chen, Q | 1 |
| Wu, W | 1 |
| Yan, X | 1 |
| Cai, H | 1 |
| Zhang, Z | 1 |
| Shao, Q | 1 |
| Qin, W | 1 |
| Marongiu, F | 1 |
| Serra, MP | 1 |
| Sini, M | 1 |
| Angius, F | 1 |
| Laconi, E | 1 |
| Thumvijit, T | 1 |
| Punvittayagul, C | 1 |
| Peerapornpisal, Y | 1 |
| Umemura, A | 1 |
| Park, EJ | 1 |
| Taniguchi, K | 1 |
| Lee, JH | 1 |
| Shalapour, S | 1 |
| Valasek, MA | 1 |
| Aghajan, M | 1 |
| Nakagawa, H | 1 |
| Seki, E | 1 |
| Hall, MN | 1 |
| Karin, M | 2 |
| Kim, YH | 1 |
| Kwak, KA | 1 |
| Kang, JS | 1 |
| Zhang, N | 1 |
| Chu, ES | 1 |
| Zhang, J | 3 |
| Li, X | 3 |
| Liang, Q | 1 |
| Chen, J | 1 |
| Chen, M | 1 |
| Teoh, N | 2 |
| Farrell, G | 2 |
| Sung, JJ | 1 |
| Yu, J | 4 |
| Caviglia, JM | 1 |
| Schwabe, RF | 2 |
| Fujisawa, K | 1 |
| Terai, S | 2 |
| Matsumoto, T | 1 |
| Takami, T | 2 |
| Yamamoto, N | 1 |
| Nishina, H | 1 |
| Furutani-Seiki, M | 1 |
| Sakaida, I | 2 |
| Peng, B | 1 |
| Liu, F | 1 |
| Han, R | 1 |
| Luo, G | 1 |
| Cathopoulis, T | 1 |
| Lu, K | 1 |
| Yang, L | 2 |
| Liu, GY | 1 |
| Cai, JC | 1 |
| Shi, SL | 1 |
| Konzack, A | 1 |
| Jakupovic, M | 1 |
| Kubaichuk, K | 1 |
| Görlach, A | 1 |
| Dombrowski, F | 1 |
| Miinalainen, I | 1 |
| Sormunen, R | 1 |
| Kietzmann, T | 1 |
| Pradhan-Sundd, T | 1 |
| Poddar, M | 1 |
| Singh, S | 1 |
| Kikuchi, A | 1 |
| Stolz, DB | 1 |
| Shou, W | 1 |
| Li, Z | 2 |
| Nejak-Bowen, KN | 1 |
| Monga, SP | 1 |
| Scheving, LA | 1 |
| Zhang, X | 1 |
| Stevenson, MC | 1 |
| Weintraub, MA | 1 |
| Abbasi, A | 1 |
| Clarke, AM | 1 |
| Threadgill, DW | 1 |
| Russell, WE | 1 |
| Wong, HJ | 1 |
| Blackburn, AC | 1 |
| Board, P | 1 |
| Xue, F | 1 |
| Hu, L | 2 |
| Ge, R | 1 |
| Liu, K | 1 |
| Li, Y | 1 |
| Sun, Y | 1 |
| Wang, K | 1 |
| Seifert, L | 1 |
| Deutsch, M | 1 |
| Alothman, S | 1 |
| Alqunaibit, D | 1 |
| Werba, G | 1 |
| Pansari, M | 1 |
| Pergamo, M | 1 |
| Ochi, A | 1 |
| Torres-Hernandez, A | 1 |
| Levie, E | 1 |
| Tippens, D | 1 |
| Greco, SH | 1 |
| Tiwari, S | 1 |
| Ly, NNG | 1 |
| Eisenthal, A | 1 |
| van Heerden, E | 1 |
| Avanzi, A | 1 |
| Barilla, R | 1 |
| Zambirinis, CP | 1 |
| Rendon, M | 1 |
| Daley, D | 1 |
| Pachter, HL | 1 |
| Hajdu, C | 1 |
| Miller, G | 1 |
| Kujawska, M | 1 |
| Ewertowska, M | 1 |
| Adamska, T | 1 |
| Ignatowicz, E | 1 |
| Gramza-Michałowska, A | 1 |
| Jodynis-Liebert, J | 1 |
| Miyazaki, T | 1 |
| Shirakami, Y | 2 |
| Kubota, M | 1 |
| Ideta, T | 1 |
| Kochi, T | 1 |
| Sakai, H | 1 |
| Tanaka, T | 1 |
| Moriwaki, H | 1 |
| Shimizu, M | 1 |
| Kuwata, K | 1 |
| Inoue, K | 1 |
| Ichimura, R | 1 |
| Takahashi, M | 1 |
| Kodama, Y | 1 |
| Yoshida, M | 1 |
| Sun, L | 1 |
| Beggs, K | 1 |
| Borude, P | 1 |
| Edwards, G | 1 |
| Bhushan, B | 1 |
| Walesky, C | 1 |
| Roy, N | 1 |
| Manley, MW | 1 |
| Gunewardena, S | 1 |
| O'Neil, M | 1 |
| Li, H | 1 |
| Apte, U | 1 |
| Bhattacharya, S | 1 |
| Reddy, D | 1 |
| Ingle, A | 1 |
| Khade, B | 1 |
| Gupta, S | 5 |
| Gamal-Eldeen, AM | 1 |
| Moustafa, D | 1 |
| El-Daly, SM | 1 |
| El-Hussieny, EA | 1 |
| Saleh, S | 1 |
| Khoobchandani, M | 1 |
| Bacon, KL | 1 |
| Katti, K | 1 |
| Shukla, R | 1 |
| Katti, KV | 1 |
| Wei, T | 1 |
| Chen, W | 1 |
| Wen, L | 1 |
| Yang, J | 2 |
| Liu, H | 3 |
| Chen, BW | 1 |
| Feng, X | 1 |
| Yang, Q | 1 |
| Bai, X | 1 |
| Liang, T | 1 |
| Sivaperumal, R | 1 |
| Angioni, MM | 1 |
| Bellofatto, K | 1 |
| Merlin, S | 1 |
| Menegon, S | 1 |
| Perra, A | 2 |
| Petrelli, A | 1 |
| Sulas, P | 1 |
| Giordano, S | 2 |
| Columbano, A | 2 |
| Follenzi, A | 1 |
| Duan, T | 1 |
| Sun, W | 3 |
| Zhang, M | 1 |
| Ge, J | 1 |
| He, Y | 1 |
| Zheng, Y | 2 |
| Yang, W | 3 |
| Shen, HM | 1 |
| Zhu, X | 1 |
| Yu, P | 1 |
| Wójcik, M | 1 |
| Bobowiec, R | 1 |
| Martelli, F | 1 |
| Ibrahim, SS | 1 |
| Nassar, NN | 1 |
| Phillips, JM | 2 |
| Burgoon, LD | 1 |
| Goodman, JI | 2 |
| Das, T | 1 |
| Patra, F | 1 |
| Mukherjee, B | 1 |
| Greenberg, AS | 1 |
| Russell, RM | 1 |
| Swisshelm, K | 1 |
| Hou, J | 1 |
| Mitchell, C | 1 |
| Fausto, N | 1 |
| Gu, Y | 1 |
| Alwahaibi, NY | 1 |
| Budin, SB | 1 |
| Mohamed, J | 1 |
| Alhamdani, A | 1 |
| Majumder, S | 1 |
| Roy, S | 1 |
| Kaffenberger, T | 1 |
| Wang, B | 1 |
| Costinean, S | 1 |
| Frankel, W | 1 |
| Bratasz, A | 1 |
| Kuppusamy, P | 1 |
| Hai, T | 1 |
| Ghoshal, K | 1 |
| Jacob, ST | 1 |
| Liu, WB | 1 |
| Cui, ZH | 1 |
| Ao, L | 1 |
| Zhou, ZY | 1 |
| Zhou, YH | 1 |
| Yuan, XY | 1 |
| Xiang, YL | 1 |
| Liu, JY | 1 |
| Cao, J | 1 |
| Khan, MS | 1 |
| Devaraj, H | 1 |
| Devaraj, N | 1 |
| Khare, SP | 1 |
| Sharma, A | 1 |
| Deodhar, KK | 1 |
| Kluwe, J | 1 |
| Wongsiriroj, N | 1 |
| Troeger, JS | 1 |
| Gwak, GY | 1 |
| Dapito, DH | 1 |
| Pradere, JP | 1 |
| Jiang, H | 1 |
| Siddiqi, M | 1 |
| Piantedosi, R | 1 |
| O'Byrne, SM | 1 |
| Blaner, WS | 2 |
| Leoni, VP | 1 |
| Ledda-Columbano, GM | 1 |
| Pibiri, M | 1 |
| Saliba, C | 1 |
| Kowalik, MA | 1 |
| Grober, OM | 1 |
| Ravo, M | 1 |
| Weisz, A | 1 |
| Locker, J | 1 |
| Ghiso, E | 1 |
| Llorente Izquierdo, C | 1 |
| Mayoral, R | 1 |
| Flores, JM | 1 |
| García-Palencia, P | 1 |
| Cucarella, C | 1 |
| Boscá, L | 1 |
| Casado, M | 1 |
| Martín-Sanz, P | 1 |
| Calvisi, DF | 1 |
| Wakabayashi, N | 1 |
| Okabe, K | 1 |
| Hayashi, M | 1 |
| Honoki, K | 1 |
| Tsujiuchi, T | 1 |
| Wang, X | 3 |
| Leibowitz, B | 1 |
| Nakamura, M | 1 |
| Kitaura, J | 1 |
| Enomoto, Y | 1 |
| Lu, Y | 1 |
| Nishimura, K | 1 |
| Isobe, M | 1 |
| Ozaki, K | 2 |
| Komeno, Y | 1 |
| Nakahara, F | 1 |
| Oki, T | 1 |
| Kume, H | 1 |
| Homma, Y | 1 |
| Kitamura, T | 1 |
| Xie, R | 1 |
| Liu, L | 1 |
| Xie, XL | 1 |
| Wei, M | 1 |
| Kakehashi, A | 1 |
| Yamano, S | 1 |
| Tajiri, M | 1 |
| Wanibuchi, H | 1 |
| Gottesman, ME | 1 |
| Yu, H | 1 |
| Wang, Q | 1 |
| Chen, P | 1 |
| Hu, XT | 1 |
| Cai, XJ | 1 |
| Guan, XY | 1 |
| Maeda, M | 1 |
| Sanders, JA | 1 |
| Brilliant, KE | 1 |
| Clift, D | 1 |
| Patel, A | 1 |
| Cerretti, B | 1 |
| Claro, P | 1 |
| Mills, DR | 1 |
| Hixson, DC | 2 |
| Gruppuso, PA | 1 |
| Srivastava, J | 1 |
| Siddiq, A | 1 |
| Emdad, L | 1 |
| Santhekadur, PK | 1 |
| Chen, D | 1 |
| Gredler, R | 1 |
| Shen, XN | 1 |
| Robertson, CL | 1 |
| Dumur, CI | 1 |
| Hylemon, PB | 1 |
| Mukhopadhyay, ND | 1 |
| Bhere, D | 1 |
| Shah, K | 1 |
| Ahmad, R | 1 |
| Giashuddin, S | 1 |
| Stafflinger, J | 1 |
| Subler, MA | 1 |
| Windle, JJ | 1 |
| Fisher, PB | 1 |
| Sarkar, D | 1 |
| Wu, J | 1 |
| Salcedo, R | 1 |
| Trinchieri, G | 1 |
| Horuzsko, A | 1 |
| Vargas-Olvera, CY | 1 |
| Sánchez-González, DJ | 1 |
| Solano, JD | 1 |
| Aguilar-Alonso, FA | 1 |
| Montalvo-Muñoz, F | 1 |
| Martínez-Martínez, CM | 1 |
| Medina-Campos, ON | 1 |
| Ibarra-Rubio, ME | 1 |
| Yan, J | 2 |
| Wang, Z | 2 |
| Hua, F | 2 |
| Li, K | 1 |
| Yang, H | 1 |
| Lv, Q | 1 |
| Xue, J | 1 |
| Hu, ZW | 2 |
| Wang, M | 1 |
| Halasi, M | 1 |
| Kabirov, K | 1 |
| Banerjee, A | 1 |
| Landolfi, J | 1 |
| Lyubimov, AV | 1 |
| Gartel, AL | 1 |
| Wu, K | 1 |
| Ding, J | 1 |
| Ning, BF | 1 |
| Wen, W | 1 |
| Huang, L | 1 |
| Han, T | 1 |
| Feng, GS | 1 |
| Xie, WF | 1 |
| Wang, HY | 1 |
| Miyakoshi, M | 1 |
| Yamamoto, M | 1 |
| Tanaka, H | 1 |
| Ogawa, K | 4 |
| Blomme, B | 1 |
| Heindryckx, F | 1 |
| Stassen, JM | 1 |
| Geerts, A | 1 |
| Colle, I | 1 |
| Van Vlierberghe, H | 1 |
| Luo, D | 1 |
| Liu, D | 1 |
| Zhou, X | 1 |
| Yang, S | 1 |
| Tang, C | 1 |
| Liu, G | 1 |
| Ainslie, GR | 1 |
| Muskhelishvili, L | 1 |
| Izawa, T | 1 |
| Yamate, J | 1 |
| Kosyk, O | 1 |
| Shymonyak, S | 1 |
| Bradford, BU | 1 |
| Boorman, GA | 1 |
| Bataller, R | 1 |
| Lv, X | 1 |
| Mi, S | 1 |
| Wang, J | 1 |
| Myburg, RB | 1 |
| Dutton, MF | 1 |
| Chuturgoon, AA | 1 |
| Sundarrajan, M | 2 |
| Rao, KV | 2 |
| Ivanov, VA | 1 |
| Martinson, TG | 1 |
| Tiuriaeva, II | 1 |
| Ha, WS | 1 |
| Kim, CK | 1 |
| Song, SH | 1 |
| Kang, CB | 1 |
| Amin, I | 1 |
| Koh, BK | 1 |
| Asmah, R | 1 |
| Jaworski, M | 1 |
| Buchmann, A | 3 |
| Bauer, P | 1 |
| Riess, O | 1 |
| Schwarz, M | 3 |
| Maeda, S | 1 |
| Kamata, H | 1 |
| Luo, JL | 1 |
| Leffert, H | 1 |
| Kuriyama, S | 1 |
| Noguchi, R | 1 |
| Yoshii, J | 1 |
| Ikenaka, Y | 1 |
| Yanase, K | 1 |
| Yamazaki, M | 1 |
| Akahane, T | 1 |
| Asada, K | 1 |
| Tsujimoto, T | 1 |
| Uemura, M | 1 |
| Fukui, H | 1 |
| Kitamura, Y | 1 |
| Umemura, T | 1 |
| Okazaki, K | 1 |
| Kanki, K | 1 |
| Imazawa, T | 1 |
| Masegi, T | 1 |
| Nishikawa, A | 1 |
| Hirose, M | 2 |
| Huang, X | 1 |
| Yu, C | 1 |
| Jin, C | 1 |
| Kobayashi, M | 1 |
| Bowles, CA | 1 |
| Kaledin, VI | 1 |
| Il'nitskaia, SI | 1 |
| Baginskaia, NV | 1 |
| Kholodar', AV | 1 |
| Obut, TA | 1 |
| Ramakrishnan, G | 2 |
| Raghavendran, HR | 1 |
| Vinodhkumar, R | 2 |
| Devaki, T | 2 |
| Chakraborty, T | 3 |
| Chatterjee, A | 3 |
| Saralaya, MG | 1 |
| Chatterjee, M | 4 |
| Waddell, WJ | 1 |
| Zhu, B | 1 |
| Liu, GT | 1 |
| Wu, RS | 1 |
| Strada, SJ | 1 |
| Carrasco-Legleu, CE | 2 |
| Sánchez-Pérez, Y | 1 |
| Márquez-Rosado, L | 2 |
| Fattel-Fazenda, S | 1 |
| Arce-Popoca, E | 2 |
| Hernández-García, S | 1 |
| Villa-Treviño, S | 2 |
| Yamamoto, Y | 1 |
| Negishi, M | 1 |
| Maronpot, RR | 1 |
| Rana, A | 1 |
| Dhachinamoorthi, D | 1 |
| Kumar P, A | 1 |
| Chen, WL | 1 |
| Louie, SG | 1 |
| Yen, TS | 1 |
| Ou, JH | 1 |
| Swamy, AH | 1 |
| Rana, B | 1 |
| Shyamsundar, A | 1 |
| Trejo-Solís, C | 1 |
| Cabrales-Romero, Mdel P | 1 |
| Sierra-Santoyo, A | 1 |
| Alemán-Lazarini, L | 1 |
| Fatel-Fazenda, S | 1 |
| Sakakima, Y | 1 |
| Hayakawa, A | 1 |
| Nagasaka, T | 1 |
| Nakao, A | 1 |
| Zhang, JJ | 1 |
| Bu, XY | 1 |
| Lou, YQ | 1 |
| Zhang, GL | 1 |
| Augustine, TA | 1 |
| Jagan, S | 1 |
| Yadav, AS | 1 |
| Bhatnagar, D | 1 |
| Shi, ZM | 1 |
| Feng, P | 1 |
| Wen, ZY | 1 |
| Subramanian, P | 1 |
| Mirunalini, S | 1 |
| Dakshayani, KB | 1 |
| Pandi-Perumal, SR | 1 |
| Trakht, I | 1 |
| Cardinali, DP | 1 |
| Finnberg, N | 1 |
| Klein-Szanto, AJ | 1 |
| El-Deiry, WS | 1 |
| Furuta, K | 1 |
| Miyake, T | 1 |
| Okamoto, E | 1 |
| Ishine, J | 1 |
| Ishihara, S | 1 |
| Amano, Y | 1 |
| Adachi, K | 1 |
| Kinoshita, Y | 1 |
| Zheng, JF | 1 |
| Liang, LJ | 1 |
| Higgins, PJ | 5 |
| Staiano-Coico, L | 1 |
| Evenson, DP | 1 |
| Melamed, MR | 1 |
| Takahashi, S | 1 |
| Lombardi, B | 1 |
| Shinozuka, H | 1 |
| Becker, FF | 3 |
| Borenfreund, E | 3 |
| Bendich, A | 3 |
| Banerjee, MR | 2 |
| Gurkalo, VK | 2 |
| Zabezhinskiĭ, MA | 2 |
| Sukumar, S | 1 |
| Pulciani, S | 1 |
| Doniger, J | 1 |
| DiPaolo, JA | 4 |
| Evans, CH | 5 |
| Zbar, B | 1 |
| Barbacid, M | 1 |
| Barbason, H | 5 |
| Betz, EH | 3 |
| Ransom, JH | 2 |
| Curtin, NJ | 1 |
| Snell, K | 1 |
| Ehlvest, J | 1 |
| Veidebaum, T | 1 |
| Põldvere, E | 1 |
| Teras, LE | 1 |
| Kildema, LA | 1 |
| Birk, RV | 1 |
| Rassenfosse, C | 1 |
| Jiao, BZ | 1 |
| Seĭts, IF | 1 |
| Glebov, AV | 1 |
| Berdinskikh, NK | 2 |
| Mel'nikova, NN | 2 |
| Livshits, VI | 1 |
| Sanina, KL | 1 |
| Gula, EP | 1 |
| Pyldvere, EI | 1 |
| Veĭdebaum, TI | 1 |
| Dragan, Y | 1 |
| Teeguarden, J | 1 |
| Campbell, H | 1 |
| Hsia, S | 1 |
| Pitot, H | 1 |
| Herens, C | 2 |
| Jacquemart, M | 1 |
| Koulischer, L | 2 |
| Massart, S | 1 |
| Bouzahzah, B | 1 |
| Matuoka, K | 1 |
| Markus, I | 1 |
| Wong, A | 1 |
| Smith, GJ | 1 |
| Goodwin, AE | 1 |
| Grizzle, JM | 1 |
| Nesnow, S | 1 |
| Beck, S | 1 |
| Rosenblum, S | 1 |
| Lasley, J | 1 |
| Tiano, HF | 1 |
| Hosokawa, M | 1 |
| Crespi, CL | 1 |
| Langenbach, R | 1 |
| Teeter, LD | 1 |
| Estes, M | 1 |
| Chan, JY | 1 |
| Atassi, H | 1 |
| Sell, S | 1 |
| Kuo, MT | 1 |
| Neveu, MJ | 1 |
| Hully, JR | 1 |
| Babcock, KL | 1 |
| Hertzberg, EL | 1 |
| Nicholson, BJ | 1 |
| Paul, DL | 1 |
| Pitot, HC | 3 |
| Li, ZQ | 1 |
| Emura, M | 2 |
| Ochiai, A | 1 |
| Gobert-Bohlen, A | 1 |
| Panning, B | 1 |
| Dungworth, DL | 1 |
| Kato, T | 2 |
| Asamoto, M | 1 |
| Wild, CP | 1 |
| Montesano, R | 1 |
| Nagao, S | 1 |
| Iwase, T | 1 |
| Matsumoto, K | 1 |
| Tsuda, H | 2 |
| Imaida, K | 1 |
| Hesegawa, R | 1 |
| Shirai, T | 2 |
| Tatematsu, M | 1 |
| Höhne, MW | 1 |
| Zieroth, S | 1 |
| Veser, U | 1 |
| Kahl, GF | 1 |
| Schwarz, LR | 1 |
| Burr, AW | 1 |
| Toole, K | 1 |
| Mathew, J | 1 |
| Hines, JE | 1 |
| Chapman, C | 1 |
| Burt, AD | 1 |
| Poole, TM | 1 |
| Chiaverotti, TA | 1 |
| Carabeo, RA | 1 |
| Drinkwater, NR | 1 |
| Gönül, B | 1 |
| Söylemezoğlu, T | 1 |
| Erbas, D | 1 |
| De Miglio, MR | 1 |
| Simile, MM | 1 |
| Muroni, MR | 1 |
| Pusceddu, S | 1 |
| Calvisi, D | 1 |
| Carru, A | 1 |
| Seddaiu, MA | 1 |
| Daino, L | 1 |
| Deiana, L | 1 |
| Pascale, RM | 1 |
| Feo, F | 1 |
| Hara, A | 1 |
| Yoshimi, N | 1 |
| Yamada, Y | 1 |
| Matsunaga, K | 1 |
| Kawabata, K | 1 |
| Sugie, S | 1 |
| Mori, H | 1 |
| Harréus, UA | 1 |
| Wallner, BC | 1 |
| Kastenbauer, ER | 1 |
| Kleinsasser, NH | 1 |
| Anis, KV | 1 |
| Rajeshkumar, NV | 1 |
| Kuttan, R | 1 |
| Im, YH | 1 |
| Kim, HT | 1 |
| Kim, IY | 1 |
| Hahm, KB | 1 |
| Anzano, M | 1 |
| Jang, JJ | 1 |
| Flanders, K | 1 |
| Thorgeirsson, SS | 2 |
| Sizeland, A | 1 |
| Kim, SJ | 1 |
| Scherer, E | 2 |
| Emmelot, P | 2 |
| Letnansky, K | 1 |
| Rubenchik, BL | 1 |
| Romanenko, AM | 1 |
| Miller, FR | 1 |
| Blazkovec, AA | 1 |
| Roane, PR | 1 |
| Medline, A | 2 |
| Farber, E | 2 |
| Rabin, ES | 1 |
| Katsuta, H | 1 |
| Takaoka, T | 1 |
| Solt, D | 1 |
| Cameron, R | 1 |
| Laishes, B | 1 |
| Steinglass, M | 1 |
| Tyndall, RL | 1 |
| Colyer, S | 1 |
| Clapp, N | 1 |
| Roth, J | 1 |
| Popescu, NC | 1 |
| Sunday, ME | 1 |
| Willett, CG | 1 |
| Bauer-Hofmann, R | 1 |
| Klimek, F | 1 |
| Müller, O | 1 |
| Bannasch, P | 1 |
| Zeindl-Eberhart, E | 1 |
| Rabes, HM | 1 |
| Kemp, DR | 1 |
| Percy, DH | 1 |
| Hayes, MA | 1 |
| Luebeck, EG | 1 |
| Moolgavkar, SH | 1 |
| Gunning, WT | 1 |
| Castonguay, A | 1 |
| Goldblatt, PJ | 1 |
| Stoner, GD | 1 |
| Stenius, U | 1 |
| Rubin, K | 1 |
| Gullberg, D | 1 |
| Högberg, J | 1 |
| Faris, RA | 1 |
| Monfils, BA | 1 |
| Dunsford, HA | 1 |
| Jirtle, RL | 1 |
| Meyer, SA | 1 |
| Wang, JH | 1 |
| Hinrichsen, LI | 1 |
| Whitacre, CM | 1 |
| Cechner, RL | 1 |
| Sudilovsky, O | 1 |
| Kirsch-Volders, M | 2 |
| Deleener, A | 2 |
| Lans, M | 3 |
| de Gerlache, J | 3 |
| Evarts, RP | 1 |
| Marsden, E | 1 |
| Pascale, R | 1 |
| Narasimhan, S | 1 |
| Rajalakshmi, S | 1 |
| Dubovaia, TK | 1 |
| Kobliakov, VA | 1 |
| Merkulova, IB | 1 |
| Politova, SN | 1 |
| Mandl, J | 1 |
| Bánhegyi, G | 1 |
| Garzó, T | 1 |
| Lapis, K | 1 |
| Antoni, F | 1 |
| Schaff, Z | 1 |
| Stowers, SJ | 1 |
| Wiseman, RW | 1 |
| Ward, JM | 2 |
| Miller, EC | 1 |
| Miller, JA | 1 |
| Anderson, MW | 1 |
| Eva, A | 1 |
| Schwarze, PE | 1 |
| Seglen, PO | 1 |
| Glauert, HP | 1 |
| Hanigan, M | 1 |
| Swenberg, JA | 1 |
| Boucheron, JA | 1 |
| Deal, FH | 1 |
| Richardson, FC | 1 |
| Tyeryar, LA | 1 |
| Hand, D | 1 |
| Elliott, BM | 1 |
| Griffin, M | 1 |
| Manoharan, K | 1 |
| Schechtman, LM | 2 |
| Hatch, GG | 1 |
| Anderson, TM | 1 |
| Putman, DL | 1 |
| Kouri, RE | 2 |
| Cameron, JW | 1 |
| Nims, RW | 1 |
| Spalding, JW | 1 |
| Tennant, RW | 1 |
| Lubet, RA | 2 |
| Poli, G | 1 |
| Cecchini, G | 1 |
| Biasi, F | 1 |
| Chiarpotto, E | 1 |
| Canuto, RA | 1 |
| Biocca, ME | 1 |
| Muzio, G | 1 |
| Esterbauer, H | 1 |
| Dianzani, MU | 1 |
| Kiss, E | 1 |
| McCarvill, J | 1 |
| Nims, R | 1 |
| Jeney, A | 1 |
| Corral, M | 1 |
| Paris, B | 1 |
| Guguen-Guillouzo, C | 1 |
| Corcos, D | 1 |
| Kruh, J | 1 |
| Defer, N | 1 |
| Ostrowski, JL | 1 |
| Ingleton, PM | 1 |
| Underwood, JC | 1 |
| Parsons, MA | 1 |
| Huang, M | 2 |
| Wang, XQ | 2 |
| Wang, ZH | 2 |
| Zhou, CN | 1 |
| Wu, M | 2 |
| Diwan, BA | 1 |
| Ohshima, M | 1 |
| Hu, H | 1 |
| Schuller, HM | 1 |
| Rice, JM | 1 |
| Ogiso, T | 1 |
| Ito, N | 1 |
| Préat, V | 1 |
| Roberfroid, M | 1 |
| Sivak, A | 1 |
| Tu, AS | 1 |
| Peraino, C | 1 |
| Vesselinovitch, SD | 1 |
| Sugioka, Y | 1 |
| Fujii-Kuriyama, Y | 1 |
| Kitagawa, T | 1 |
| Muramatsu, M | 1 |
| Mohr, U | 1 |
| Kakunaga, T | 1 |
| Hilfrich, J | 1 |
6 reviews available for diethylnitrosamine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Critique of dose response in carcinogenesis.
Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Carcinogenicity Tests; Carcinogens; Cell Transformation, | 2006 |
The quantitation of altered hepatic foci during multistage hepatocarcinogenesis in the rat: transforming growth factor alpha expression as a marker for the stage of progression.
Topics: Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Count; Cell Transformation, Neoplastic; | 1995 |
Genetic analysis of multistage hepatocarcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Diethylnitrosamine; Disease | 1996 |
The significance of selected biochemical markers in the characterization of putative initiated cell populations in rodent liver.
Topics: Adenosine Triphosphatases; Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Diethylnitros | 1985 |
Trends in pathobiochemical studies of tumour development and progression.
Topics: Animals; Cell Transformation, Neoplastic; Chromatin; Diethylnitrosamine; DNA; Homeostasis; Humans; L | 1986 |
Single-hit versus multi-hit concept of hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Age Factors; Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylni | 1985 |
212 other studies available for diethylnitrosamine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Low-polar extract from seed of Cleistocalyx nervosum var. paniala modulates initiation and promotion stages of chemically-induced carcinogenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Co | 2021 |
Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosa | 2021 |
Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regeneration.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Diethylnitrosamine; | 2021 |
Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cholesterol; Diethylnitrosamine | 2017 |
Modulatory efficacy of dieckol on xenobiotic-metabolizing enzymes, cell proliferation, apoptosis, invasion and angiogenesis during NDEA-induced rat hepatocarcinogenesis.
Topics: Animals; Apoptosis; Benzofurans; Cell Proliferation; Cell Transformation, Neoplastic; Diethylnitrosa | 2017 |
Deriving and testing of dysplastic murine hepatocytes: A new platform in liver cancer research.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Cell Transformation, | 2017 |
Time-caloric restriction inhibits the neoplastic transformation of cirrhotic liver in rats treated with diethylnitrosamine.
Topics: Animals; Caloric Restriction; Carcinogenesis; Carcinoma, Hepatocellular; Cell Transformation, Neopla | 2017 |
Tg737 regulates epithelial-mesenchymal transition and cancer stem cell properties via a negative feedback circuit between Snail and HNF4α during liver stem cell malignant transformation.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Cell Proliferation; Cell Transformation, N | 2017 |
Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis.
Topics: Animals; Cell Survival; Cell Transformation, Neoplastic; Diethylnitrosamine; Hepatocytes; Liver Neop | 2017 |
Dioxin Receptor Adjusts Liver Regeneration After Acute Toxic Injury and Protects Against Liver Carcinogenesis.
Topics: Animals; Biomarkers; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Diethy | 2017 |
Activation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cyclin D1; Diethylnitrosamine; | 2017 |
Caspase-3 suppresses diethylnitrosamine-induced hepatocyte death, compensatory proliferation and hepatocarcinogenesis through inhibiting p38 activation.
Topics: Animals; Carcinoma, Hepatocellular; Caspase 3; Cell Death; Cell Proliferation; Cell Transformation, | 2018 |
Inhibitory effects of mushroom extracts on progression of carcinogenesis in mice.
Topics: Agaricus; Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Transfo | 2018 |
Acyclic retinoid and angiotensin-II receptor blocker exert a combined protective effect against diethylnitrosamine-induced hepatocarcinogenesis in diabetic OLETF rats.
Topics: Angiotensin Receptor Antagonists; Animals; Biomarkers; Cell Line, Tumor; Cell Proliferation; Cell Tr | 2018 |
Expression Characteristics of Genes Hypermethylated and Downregulated in Rat Liver Specific to Nongenotoxic Hepatocarcinogens.
Topics: Animals; Cadherins; Carbon Tetrachloride; Cell Proliferation; Cell Transformation, Neoplastic; Dieth | 2019 |
The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling Pathways.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Diethylnitrosamine; Disease Pro | 2019 |
Pantoprazole attenuates tumorigenesis via inhibition of exosomal secretion in a rat model of hepatic precancerous lesion induced by diethylnitrosamine and 2-acetamidofluorene.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Diethyln | 2019 |
An Immune Gene Expression Signature Associated With Development of Human Hepatocellular Carcinoma Identifies Mice That Respond to Chemopreventive Agents.
Topics: Animals; Anticarcinogenic Agents; Aspirin; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Contro | 2019 |
Paradoxical role of autophagy in the dysplastic and tumor-forming stages of hepatocarcinoma development in rats.
Topics: Animals; Antioxidants; Autophagy; Carcinoma, Hepatocellular; Cell Proliferation; Cell Transformation | 2013 |
Garlic oil attenuated nitrosodiethylamine-induced hepatocarcinogenesis by modulating the metabolic activation and detoxification enzymes.
Topics: Allyl Compounds; Animals; Biotransformation; Carcinogens, Environmental; Cell Transformation, Neopla | 2013 |
Protective effects of Scutellaria barbata against rat liver tumorigenesis.
Topics: Alanine Transaminase; Alkaline Phosphatase; alpha-L-Fucosidase; Animals; Aspartate Aminotransferases | 2013 |
Hepatocellular carcinoma as extracolonic manifestation of Lynch syndrome indicates SEC63 as potential target gene in hepatocarcinogenesis.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Animals; Apoptosis; Carcinoma, Hepa | 2013 |
Cyclin E facilitates dysplastic hepatocytes to bypass G1/S checkpoint in hepatocarcinogenesis.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Cell Transformation, Neoplastic; | 2013 |
Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress.
Topics: AMP-Activated Protein Kinases; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; | 2013 |
Synergistic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and N-nitrosodiethylamine on cell malignant transformation.
Topics: 3T3 Cells; Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cytochrome P-450 En | 2013 |
Role of phosphorylated histone H3 serine 10 in DEN-induced deregulation of Pol III genes and cell proliferation and transformation.
Topics: Alkylating Agents; Animals; Apoptosis; Blotting, Western; Butyrate Response Factor 1; Cell Adhesion; | 2013 |
Expansion of hepatic stem cell compartment boosts liver regeneration.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Different | 2014 |
Lycopene metabolite, apo-10'-lycopenoic acid, inhibits diethylnitrosamine-initiated, high fat diet-promoted hepatic inflammation and tumorigenesis in mice.
Topics: Alkylating Agents; Animals; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Carotenoids; Ce | 2013 |
Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice.
Topics: Animals; beta Catenin; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Transformation, Neoplas | 2014 |
Loss of the nucleosome-binding protein HMGN1 affects the rate of N-nitrosodiethylamine-induced hepatocarcinogenesis in mice.
Topics: Animals; Cell Transformation, Neoplastic; Chromatin; Diethylnitrosamine; Gene Expression Profiling; | 2014 |
Enhancement of DEN-induced liver tumourigenesis in hepatocyte-specific Lass2-knockout mice coincident with upregulation of the TGF-β1-Smad4-PAI-1 axis.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Cell Transformation, Neoplastic; | 2014 |
Clearance of senescent hepatocytes in a neoplastic-prone microenvironment delays the emergence of hepatocellular carcinoma.
Topics: Animals; Biomarkers; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cellular Microenvir | 2014 |
Cancer chemopreventive effect of Spirogyra neglecta (Hassall) Kützing on diethylnitrosamine-induced hepatocarcinogenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Transformation, Neoplastic; Chemoprevention; Dieth | 2014 |
Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinoma, Hepatocellular; Cell Proliferation; Cell T | 2014 |
Expression of neighbor of Punc E11 in hepatocarcinogenesis induced by diethylnitrosamine.
Topics: alpha-Fetoproteins; Animals; Cadherins; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnit | 2014 |
Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-κB signaling pathway.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Binding Sites; Carcinoma, Hepatocellular; Cell Pr | 2014 |
Mouse models of liver cancer.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; | 2015 |
Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging.
Topics: Aging; Amino Acid Sequence; Animals; Animals, Genetically Modified; Carcinogenesis; Carcinoma, Hepat | 2015 |
Dynamic metabolic change is indicative of inflammation-induced transformation of hepatic cells.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chemical and | 2015 |
Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Proliferation; Cell Shape; Cell Transformatio | 2015 |
Mice with Hepatic Loss of the Desmosomal Protein γ-Catenin Are Prone to Cholestatic Injury and Chemical Carcinogenesis.
Topics: Animals; beta Catenin; Bile Ducts; Cell Transformation, Neoplastic; Cholestasis; Desmosomes; Diethyl | 2015 |
Loss of hepatocyte ERBB3 but not EGFR impairs hepatocarcinogenesis.
Topics: Age Factors; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Diethylnitrosamine; ErbB | 2015 |
Testosterone regulation of cyclin E kinase: A key factor in determining gender differences in hepatocarcinogenesis.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Castration; Cell Proli | 2016 |
Autophagy-deficiency in hepatic progenitor cells leads to the defects of stemness and enhances susceptibility to neoplastic transformation.
Topics: Animals; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Carbon Tetrachloride; | 2016 |
Dectin-1 Regulates Hepatic Fibrosis and Hepatocarcinogenesis by Suppressing TLR4 Signaling Pathways.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chemokine CCL2; Cytokines; Diethylnitrosa | 2015 |
Protective effect of yellow tea extract on N-nitrosodiethylamine-induced liver carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Biomarkers; Camellia sinensis; Cell Transformation, | 2016 |
Sodium alginate prevents progression of non-alcoholic steatohepatitis and liver carcinogenesis in obese and diabetic mice.
Topics: Alginates; Animals; Cell Transformation, Neoplastic; Diabetes Mellitus, Experimental; Diethylnitrosa | 2016 |
Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development.
Topics: Adenoma; Animals; Aryl Hydrocarbon Hydroxylases; Cell Proliferation; Cell Transformation, Neoplastic | 2016 |
Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling.
Topics: Adult; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Cell Transformation, Neopl | 2016 |
Brief Communication: Featured Article: Histone H2A mono-ubiquitination and cellular transformation are inversely related in N-nitrosodiethylamine-induced hepatocellular carcinoma.
Topics: Alkylating Agents; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Transformation, Neopl | 2016 |
Photothermal therapy mediated by gum Arabic-conjugated gold nanoparticles suppresses liver preneoplastic lesions in mice.
Topics: Animals; Apoptosis; Cell Survival; Cell Transformation, Neoplastic; Diethylnitrosamine; Glutathione | 2016 |
G protein-coupled estrogen receptor deficiency accelerates liver tumorigenesis by enhancing inflammation and fibrosis.
Topics: Animals; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Diethylnitrosamine | 2016 |
Protective effects of dieckol on N-nitrosodiethylamine induced hepatocarcinogenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Benzofurans; Biomarkers; Carcinoma, Hepatocellular; | 2016 |
A long term, non-tumorigenic rat hepatocyte cell line and its malignant counterpart, as tools to study hepatocarcinogenesis.
Topics: Alkylating Agents; Animals; Carcinogenesis; Cell Line; Cell Line, Transformed; Cell Transformation, | 2017 |
Dietary restriction protects against diethylnitrosamine-induced hepatocellular tumorigenesis by restoring the disturbed gene expression profile.
Topics: Animals; Apoptosis; Body Weight; Caloric Restriction; Cell Proliferation; Cell Transformation, Neopl | 2017 |
Effect of carotenoids on in vitro proliferation and differentiation of oval cells during neoplastic and non-neoplastic liver injuries in rats.
Topics: Animals; Anticarcinogenic Agents; beta Carotene; Cell Differentiation; Cell Proliferation; Cell Tran | 2008 |
Diallyl sulfide protects against N-nitrosodiethylamine-induced liver tumorigenesis: role of aldose reductase.
Topics: Aldehyde Reductase; Allyl Compounds; Animals; Anticarcinogenic Agents; Antioxidants; Cell Transforma | 2008 |
The constitutive active/androstane receptor facilitates unique phenobarbital-induced expression changes of genes involved in key pathways in precancerous liver and liver tumors.
Topics: Animals; Apoptosis; Cell Cycle; Cell Transformation, Neoplastic; Constitutive Androstane Receptor; D | 2009 |
Effect of antisense oligomer in controlling c-raf.1 overexpression during diethylnitrosamine-induced hepatocarcinogenesis in rat.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Transformation, Neoplastic; Cytochrome P-45 | 2010 |
Dietary lycopene and tomato extract supplementations inhibit nonalcoholic steatohepatitis-promoted hepatocarcinogenesis in rats.
Topics: Animals; Blotting, Western; Carcinogens; Carotenoids; Cell Transformation, Neoplastic; Chromatograph | 2010 |
Induction of p53 renders ATM-deficient mice refractory to hepatocarcinogenesis.
Topics: Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Hepatocellular; Caspase 3; Ce | 2010 |
Nuclear factor-kappa B as a promising target for selenium chemoprevention in rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Cyclin D1; | 2010 |
Loss of metallothionein predisposes mice to diethylnitrosamine-induced hepatocarcinogenesis by activating NF-kappaB target genes.
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Gene Expression Regulation, Neoplastic | 2010 |
Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.
Topics: Animals; Azacitidine; Cadherins; Cell Adhesion; Cell Adhesion Molecules; Cell Transformation, Neopla | 2011 |
Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Arrestins; beta-Arrestin | 2011 |
Overexpression of histone variant H2A.1 and cellular transformation are related in N-nitrosodiethylamine-induced sequential hepatocarcinogenesis.
Topics: Animals; Cell Transformation, Neoplastic; Densitometry; Diethylnitrosamine; Electrophoresis, Gel, Tw | 2011 |
Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis.
Topics: Acyltransferases; Animals; Carbon Tetrachloride; Cell Transformation, Neoplastic; Cells, Cultured; D | 2011 |
Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3.
Topics: Animals; Cell Cycle Checkpoints; Cell Proliferation; Cell Transformation, Neoplastic; Constitutive A | 2011 |
Transgenic mice expressing cyclooxygenase-2 in hepatocytes reveal a minor contribution of this enzyme to chemical hepatocarcinogenesis.
Topics: Aging; Animals; Body Weight; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin E; Cyclooxy | 2011 |
Of mice and men: the nonrandom genomic instability in hepatocarcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Diethylnitrosamine; Genes, myc; | 2011 |
Mutations and aberrant transcriptions of Stk11 (Lkb1) gene in rat liver tumors.
Topics: Amino Acids; AMP-Activated Protein Kinase Kinases; Animals; Carcinogens; Cell Transformation, Neopla | 2011 |
PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Apoptosis Regulatory Proteins; Biopsy, Needle; Blotting, W | 2011 |
Transforming growth factor-β-stimulated clone-22 is a negative-feedback regulator of Ras / Raf signaling: Implications for tumorigenesis.
Topics: Animals; Blotting, Western; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosamine; Ge | 2012 |
Autophagy enhanced by microtubule- and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis.
Topics: Alkylating Agents; Animals; Autophagy; Cell Transformation, Neoplastic; Diethylnitrosamine; DNA Brea | 2011 |
2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) promotes mouse hepatocarcinogenesis by activating transforming growth factor-β and Wnt/β-catenin signaling pathways.
Topics: Animals; beta Catenin; Blotting, Western; Body Weight; Carcinoma, Hepatocellular; Cell Adhesion; Cel | 2012 |
Diethylnitrosamine-induced hepatocarcinogenesis is suppressed in lecithin:retinol acyltransferase-deficient mice primarily through retinoid actions immediately after carcinogen administration.
Topics: Acyltransferases; Alanine Transaminase; Animals; Apoptosis; Carcinogens; Cell Proliferation; Cell Tr | 2012 |
Chemically-induced cancers do not originate from bone marrow-derived cells.
Topics: Abnormal Karyotype; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carcinogens; Cell Trans | 2012 |
Autologous bone marrow cell infusions suppress tumor initiation in hepatocarcinogenic mice with liver cirrhosis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Bone Marrow Transplantation; Carbon Tetrachloride; Carcinoma, | 2012 |
The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Cell Proliferation; Cell Shape; Cel | 2012 |
Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Adhesion Molecules; Cell Transformat | 2012 |
The proinflammatory myeloid cell receptor TREM-1 controls Kupffer cell activation and development of hepatocellular carcinoma.
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Kupffer Cells; Liver Neoplasms, Experi | 2012 |
Characterization of N-diethylnitrosamine-initiated and ferric nitrilotriacetate-promoted renal cell carcinoma experimental model and effect of a tamarind seed extract against acute nephrotoxicity and carcinogenesis.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Cell Transformation, Neoplastic; Diethylnitrosamine; Di | 2012 |
Loss of immunity-supported senescence enhances susceptibility to hepatocellular carcinogenesis and progression in Toll-like receptor 2-deficient mice.
Topics: Alkylating Agents; Animals; Autophagy; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; C | 2013 |
Combination treatment with bortezomib and thiostrepton is effective against tumor formation in mouse models of DEN/PB-induced liver carcinogenesis.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Carcinoma, Hepat | 2012 |
Hepatic transforming growth factor beta gives rise to tumor-initiating cells and promotes liver cancer development.
Topics: AC133 Antigen; Animals; Antigens, CD; Antigens, Differentiation; Antigens, Neoplasm; Biomarkers, Tum | 2012 |
Serine 727 phosphorylation of STAT3: an early change in mouse hepatocarcinogenesis induced by neonatal treatment with diethylnitrosamine.
Topics: Animals; Animals, Newborn; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Cell Prolifera | 2014 |
Serum protein N-glycan alterations of diethylnitrosamine-induced hepatocellular carcinoma mice and their evolution after inhibition of the placental growth factor.
Topics: Animals; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Blood Proteins; Calcium Sign | 2013 |
Bone marrow-derived cells contribute to NDEA-induced lung squamous cell carcinoma.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carcinoma, Squamous Cell; Cell Differentiat | 2013 |
Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis.
Topics: Animals; Animals, Newborn; Carbon Tetrachloride; Cell Transformation, Neoplastic; Diethylnitrosamine | 2013 |
Toll-like receptor 4 activity protects against hepatocellular tumorigenesis and progression by regulating expression of DNA repair protein Ku70 in mice.
Topics: Animals; Antigens, Nuclear; Apoptosis; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; D | 2013 |
Cytotoxicity of fumonisin B1, diethylnitrosamine, and catechol on the SNO esophageal cancer cell line.
Topics: Alkylating Agents; Carboxylic Acids; Carcinogens, Environmental; Catechols; Cell Transformation, Neo | 2002 |
Overexpression of cyclin D1 is associated with the decondensation of chromatin during den-induced sequential hepatocarcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chromatin; Cyclin D1; Diethylni | 2002 |
Tumor promotion by metanil yellow and malachite green during rat hepatocarcinogenesis is associated with dysregulated expression of cell cycle regulatory proteins.
Topics: Animals; Azo Compounds; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Transformation, Neoplas | 2003 |
[Tumor-associated hetero-organic antigens as markers of deranged cell differentiation and malignancy].
Topics: Animals; Antigens, Neoplasm; Biomarkers, Tumor; Carcinogens; Cell Differentiation; Cell Transformati | 2003 |
Study on mechanism of multistep hepatotumorigenesis in rat: development of hepatotumorigenesis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Carcinogens; Cell Transforma | 2001 |
Effect of cacao liquor extract on tumor marker enzymes during chemical hepatocarcinogenesis in rats.
Topics: 2-Acetylaminofluorene; Alkaline Phosphatase; Analysis of Variance; Animals; Biomarkers, Tumor; Cacao | 2004 |
B-raf and Ha-ras mutations in chemically induced mouse liver tumors.
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; DNA, Neoplasm; Genes, ras; Humans; Liv | 2005 |
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis.
Topics: Animals; Carcinogens; Cell Death; Cell Proliferation; Cell Transformation, Neoplastic; Cytokines; Di | 2005 |
Amelioration of carcinogenesis and tumor growth in the rat liver by combination of vitamin K2 and angiotensin-converting enzyme inhibitor via anti-angiogenic activities.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Transformation, Neoplastic; Diethylnitrosami | 2006 |
Enhancing effects of simultaneous treatment with sodium nitrite on 2-amino-3-methylimidazo[4,5-f]quinoline-induced rat liver, colon and Zymbal's gland carcinogenesis after initiation with diethylnitrosamine and 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Alkylating Agents; Animals; Carcinogens; Cell Transform | 2006 |
Ectopic activity of fibroblast growth factor receptor 1 in hepatocytes accelerates hepatocarcinogenesis by driving proliferation and vascular endothelial growth factor-induced angiogenesis.
Topics: Animals; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Diethylnitrosamine; DN | 2006 |
[Effect of phenobarbital and thyroxine on hepatocarcinogenesis initiated in mice by nitrosoethylurea and diethylnitrosamine].
Topics: Alkylating Agents; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Ethylnitrosourea; F | 2005 |
Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats.
Topics: Animals; Antioxidants; Body Weight; Cell Transformation, Neoplastic; Diethylnitrosamine; Lipid Perox | 2006 |
Chemopreventive effect of vanadium in a rodent model of chemical hepatocarcinogenesis: reflections in oxidative DNA damage, energy-dispersive X-ray fluorescence profile and metallothionein expression.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cell Transformation, Neoplastic; Chemoprevention; Deoxyguanosi | 2006 |
Chemoprevention of bicyclol against hepatic preneoplastic lesions.
Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Cell Transformation, Neoplastic; Chemoprevention | 2006 |
A single dose of caffeic acid phenethyl ester prevents initiation in a medium-term rat hepatocarcinogenesis model.
Topics: 2-Acetylaminofluorene; Animals; Caffeic Acids; Carcinogens; Cell Proliferation; Cell Transformation, | 2006 |
Orphan nuclear receptor constitutive active/androstane receptor-mediated alterations in DNA methylation during phenobarbital promotion of liver tumorigenesis.
Topics: Analysis of Variance; Animals; Carcinogens; Cell Transformation, Neoplastic; Constitutive Androstane | 2007 |
Carcinogen-induced early molecular events and its implication in the initiation of chemical hepatocarcinogenesis in rats: chemopreventive role of vanadium on this process.
Topics: Alkylating Agents; Animals; Carcinogens; Cell Transformation, Neoplastic; Chemoprevention; Deoxyguan | 2007 |
Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice.
Topics: Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; DNA, Viral; Fe | 2007 |
Molecular basis of vanadium-mediated inhibition of hepatocellular preneoplasia during experimental hepatocarcinogenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; | 2007 |
Co-carcinogenic effect of cyclohexanol on the development of preneoplastic lesions in a rat hepatocarcinogenesis model.
Topics: Alkylating Agents; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Cyclohexanols; Diet | 2007 |
Prevention of hepatocarcinogenesis with phosphatidylcholine and menaquinone-4: in vitro and in vivo experiments.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transforma | 2007 |
Effect of berberine on hepatocyte proliferation, inducible nitric oxide synthase expression, cytochrome P450 2E1 and 1A2 activities in diethylnitrosamine- and phenobarbital-treated rats.
Topics: Animals; Anticarcinogenic Agents; Berberine; Carcinogens; Cell Proliferation; Cell Transformation, N | 2008 |
Effect of silymarin on N-nitrosodiethylamine induced hepatocarcinogenesis in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; alpha-Fetoproteins; Animals; Antioxidants; Aspartate Ami | 2007 |
Chemo-preventive effect of Star anise in N-nitrosodiethylamine initiated and phenobarbital promoted hepato-carcinogenesis.
Topics: Animals; Antioxidants; Body Weight; Cell Transformation, Neoplastic; Diethylnitrosamine; Erythrocyte | 2007 |
Effect of Qi-protecting powder (Huqi San) on expression of c-jun, c-fos and c-myc in diethylnitrosamine-mediated hepatocarcinogenesis.
Topics: Alkylating Agents; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Disease Models, Ani | 2007 |
Prevention by melatonin of hepatocarcinogenesis in rats injected with N-nitrosodiethylamine.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carcinoma, Hepatocellular; Cell Transfor | 2007 |
TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis.
Topics: Alkylating Agents; Animals; Bronchitis; Cell Line, Tumor; Cell Transformation, Neoplastic; Chronic D | 2008 |
Anti-tumor effects of cimetidine on hepatocellular carcinomas in diethylnitrosamine-treated rats.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cimeti | 2008 |
Transplanted bone marrow stromal cells are not cellular origin of hepatocellular carcinomas in a mouse model of carcinogenesis.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carcinoma, Hepatocellular; Cell Differentia | 2008 |
Characterization and carcinogen sensitivity of an established endothelial-like cell line derived from adult rat liver tissue.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Diethylnitrosamin | 1984 |
Progression of carcinogen-induced foci of gamma-glutamyltranspeptidase-positive hepatocytes to hepatomas in rats fed a choline-deficient diet.
Topics: 2-Acetylaminofluorene; Animal Feed; Animals; Cell Transformation, Neoplastic; Choline Deficiency; Di | 1982 |
The direct and indirect effects of promoters may depend upon the nature of the initiated cell.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; DN | 1983 |
In vivo-in vitro rat liver carcinogenesis: modifications in protein synthesis and ultrastructure.
Topics: Albumins; Alkaline Phosphatase; alpha-Fetoproteins; Animals; Antigens, Neoplasm; Cell Line; Cell Nuc | 1980 |
N-Nitrosodiethylamine-induced nodule-like alveolar lesion and its prevention by a retinoid in BALB/c mouse mammary glands in the whole organ in culture.
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; DNA Repair; Female; Fenretinide; Mamma | 1982 |
[Effects of apomorphine and haloperidol on experimental hepatocarcinogenesis].
Topics: Adenoma; Adenoma, Bile Duct; Animals; Apomorphine; Cell Transformation, Neoplastic; Diethylnitrosami | 1983 |
A transforming ras gene in tumorigenic guinea pig cell lines initiated by diverse chemical carcinogens.
Topics: Animals; Base Sequence; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Division; Cell Line; Cell Tr | 1984 |
Liver cell control after discontinuation of DENA feeding in hepatocarcinogenesis.
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Growth Inhibitors; Homeostasis; Liver; | 1981 |
Molecular and biological characterization of anticarcinogenic and tumor cell growth-inhibitory activities of Syrian hamster lymphotoxin.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Crice | 1983 |
Enzymic retrodifferentiation during hepatocarcinogenesis and liver regeneration in rats in vivo.
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Hepatectomy; Liver; Liver Neoplasms, E | 1983 |
Role of mitotic activity in target tissues in N-nitrosodiethylamine carcinogenesis.
Topics: Animals; Carbon Tetrachloride; Cell Division; Cell Transformation, Neoplastic; Dexamethasone; Diethy | 1983 |
Alterations in carbohydrate metabolizing enzymes induced by hormones during the process of carcinogenesis.
Topics: Animals; Carbohydrate Metabolism; Cell Transformation, Neoplastic; Diethylnitrosamine; Glucosephosph | 1983 |
Promotion mechanism of phenobarbital and partial hepatectomy in DENA hepatocarcinogenesis cell kinetics effect.
Topics: Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Diethylnitrosamine; Hepatectomy; Liver N | 1983 |
[Studies on canceration of esophageal epithelium--(SEM) and (TEM) observations].
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Dimethylnitrosamine; Epit | 1983 |
Lymphotoxin prevention of diethylnitrosamine carcinogenesis in vivo.
Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; Diethylnitrosamine; Female; Lymphotoxin-alpha; | 1982 |
[Nonhistone proteins of the rat liver in malignant transformation by nitrosodiethylamine].
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; DNA; DNA, Neoplasm; Liver; Liver Neopl | 1982 |
[Protein composition of the endoplasmic reticulum of normal rat liver cells and after exposure to the carcinogen N-nitrosodiethylamine].
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Endoplasmic Reticulum; Liver Neoplasms | 1982 |
[Lipid component of endoplasmic reticulum membranes in rat liver during carcinogenesis induced by nitrosodiethylamine].
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Endoplasmic Reticulum; Lipids; Liver N | 1982 |
Proliferation of preneoplastic lesions after discontinuation of chronic DEN feeding in the development of hepatomas in rat.
Topics: Animals; Cell Count; Cell Division; Cell Transformation, Neoplastic; Diethylnitrosamine; Liver; Live | 1981 |
[Progression of new transplantable hepatomas in C3HA strain mice. I. 61EP hepatomas].
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Liver Neoplasms, Experimental; Male; M | 1980 |
Nuclear lesions during rat hepatocarcinogenesis. I. Measuring the sister-chromatid exchanges during initiation, promotion and progression of rat hepatocarcinogenesis induced with diethylnitrosamine.
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Liver Neoplasms, Experimental; Male; R | 1995 |
Nuclear lesions during rat hepatocarcinogenesis. II. Measuring the micronuclei during initiation, promotion and progression of rat hepatocarcinogenesis induced with diethylnitrosamine.
Topics: Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Diethylnitrosamine; Hepatectomy; L | 1995 |
Diethylnitrosamine- and partial hepatectomy-induced decrease in alpha 2u-globulin mRNA level in the rat liver.
Topics: Alpha-Globulins; Animals; Cell Division; Cell Transformation, Neoplastic; Diethylnitrosamine; DNA; G | 1993 |
Oncogene expression in hepatocytes of the fish Rivulus ocellatus marmoratus during the necrotic and regenerative phases of diethylnitrosamine toxicity.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Diethylnitrosamine; ErbB Receptors; Fishes; | 1994 |
N-nitrosodiethylamine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced morphological transformation of C3H/10T1/2CL8 cells expressing human cytochrome P450 2A6.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carcinogens, Environmental; Cell Transfor | 1994 |
Activation of distinct multidrug-resistance (P-glycoprotein) genes during rat liver regeneration and hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequen | 1993 |
Multiple mechanisms are responsible for altered expression of gap junction genes during oncogenesis in rat liver.
Topics: Animals; Blotting, Northern; Cell Transformation, Neoplastic; Connexin 26; Connexin 43; Connexins; D | 1994 |
[Study on initiation of human lung carcinogenesis].
Topics: Anticarcinogenic Agents; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosamine; Human | 1993 |
Neuroendocrine phenotype differentiation in a hamster lung epithelial cell line under low oxygen pressure or after transformation by diethylnitrosamine.
Topics: Animals; Cell Adhesion; Cell Differentiation; Cell Hypoxia; Cell Line; Cell Transformation, Neoplast | 1994 |
Decreased dimethylnitrosamine-induced O6- and N7-methyldeoxyguanosine levels correlate with development and progression of lesions in rat hepatocarcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Deoxyguanosine; Diethylnitrosam | 1993 |
Three-dimensional analysis of glutathione S-transferase placental form-positive lesion development in early stages of rat hepatocarcinogenesis.
Topics: Animals; Cell Transformation, Neoplastic; Computer Graphics; Diethylnitrosamine; Glutathione Transfe | 1993 |
Carcinogen-induced diploid hepatocytes: sensitive target cells for transformation by mutated c-Ha-ras oncogene.
Topics: 2-Acetylaminofluorene; Animals; Base Sequence; Cell Separation; Cell Transformation, Neoplastic; Die | 1993 |
Transforming growth factor-alpha expression is altered during experimental hepatocarcinogenesis.
Topics: Animals; Blotting, Western; Cell Division; Cell Transformation, Neoplastic; Diethylnitrosamine; Fema | 1996 |
Epidermal growth factor and glucocorticoid effects on blood prostaglandin E2 level in DENA-induced carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Dexamethasone; Diethylnitrosamine; Dinoprosto | 1996 |
Correlation of c-myc overexpression and amplification with progression of preneoplastic liver lesions to malignancy in the poorly susceptible Wistar rat strain.
Topics: 2-Acetylaminofluorene; Animals; Apoptosis; Cell Transformation, Neoplastic; Chloroform; Diethylnitro | 1999 |
Effects of Fas-mediated liver cell apoptosis on diethylnitrosamine-induced hepatocarcinogenesis in mice.
Topics: Adenoma; Alkylating Agents; Animals; Antibodies, Monoclonal; Apoptosis; Cell Transformation, Neoplas | 2000 |
[DNA repair if mucous membrane cells and lymphocytes with the comet assay].
Topics: Carcinogenicity Tests; Cell Transformation, Neoplastic; Comet Assay; Diethylnitrosamine; DNA Repair; | 2001 |
Inhibition of chemical carcinogenesis by berberine in rats and mice.
Topics: Alkylating Agents; Animals; Berberine; Cell Transformation, Neoplastic; Diethylnitrosamine; Dose-Res | 2001 |
Heterozygous mice for the transforming growth factor-beta type II receptor gene have increased susceptibility to hepatocellular carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Female; Gene Dosage; Gene | 2001 |
The natural history of neoplasia. Newer insights into an old problem.
Topics: Adenosine Triphosphatases; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Diet | 1977 |
[Modification of chemical carcinogenesis with adrenergic compounds].
Topics: Adrenergic alpha-Antagonists; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Ant | 1978 |
Foci of altered liver cells induced by a single dose of diethylnitrosamine and partial hepatectomy: their contribution to hepatocarcinogenesis in the rat.
Topics: Adenosine Triphosphatases; Age Factors; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine | 1975 |
The phosphorylation of nuclear proteins in the regenerating and premalignant rat liver and its significance for cell proliferation.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Division; Cell Transformation, Neoplastic; C | 1975 |
[Hyperplastic foci in chemical carcinogenesis].
Topics: 2-Acetylaminofluorene; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Diethyln | 1976 |
In vivo initiated rat liver carcinogenesis studied in vitro; formation of alcoholic hyaline-type bodies.
Topics: Animals; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Cytoplasm; Diethylnitrosami | 1977 |
Guinea pig cell-mediated tumor immunity: the chromium release assay detects both cytolysis and serum blocking for syngeneic chemically-induced tumors.
Topics: Animals; Binding, Competitive; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chromium | 1979 |
Inhibition of the multiplication of herpes simplex virus by aliphatic nitrosamines.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cell Transformation, Neoplastic; Cells, C | 1978 |
Sequential analysis of hepatic carcinogenesis: a comparative study of the ultrastructure of preneoplastic, malignant, prenatal, postnatal, and regenerating liver.
Topics: Animals; Carcinoma, Hepatocellular; Cell Membrane; Cell Transformation, Neoplastic; Cytoskeleton; Di | 1979 |
The susceptibility of guinea pig cells to the colony-inhibitory activity of lymphotoxin during carcinogenesis.
Topics: Animals; Ascitic Fluid; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells | 1977 |
Carcinogenesis in tissue culture 30: malignant transformation of normal rat liver cells treated with diethylnitrosamine in tissue culture with special reference to the differential effects of cytochalasin B on various cells with and without tumorigenicity
Topics: Animals; Animals, Suckling; Cell Nucleus; Cell Transformation, Neoplastic; Culture Techniques; Cytoc | 1979 |
Multi-hit kinetics of tumor formation, with special reference to experimental liver and human lung carcinogenesis and some gneral conclusions.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Dose-Response Relationshi | 1977 |
Newer insights into the pathogenesis of liver cancer.
Topics: Aflatoxins; Animals; Cell Division; Cell Transformation, Neoplastic; Diethylnitrosamine; Dimethylnit | 1977 |
Properties and malignant transformation of established rat liver parenchymal cells in culture.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Azo Compounds; Benzopyrenes; Blood Proteins; Cell Transforma | 1975 |
Early alterations in plasma esterases with associated pathology following oral administration of diethylnitrosamine and butylated hydroxytoluene singly or in combination.
Topics: Administration, Oral; Animals; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Cresols; D | 1975 |
Concanavalin A receptors on normal rat liver cells, on rat liver cells in vivo transformed by diethylnitrosamine and on Zajdela ascites hepatoma cells of the rat: morphokinetic analysis of cell surface dynamics.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Concanavalin A; Diethylnitrosamine; Liver Neopl | 1975 |
Chromosome patterns (G and C bands) of in vitro chemical carcinogen-transformed guinea pig cells.
Topics: Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; | 1976 |
Induction and spontaneous regression of intense pulmonary neuroendocrine cell differentiation in a model of preneoplastic lung injury.
Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Cricetinae; Diethylnitrosamine; Dise | 1992 |
Role of mutations at codon 61 of the c-Ha-ras gene during diethylnitrosamine-induced hepatocarcinogenesis in C3H/He mice.
Topics: Animals; Base Sequence; Cell Transformation, Neoplastic; Diethylnitrosamine; DNA Mutational Analysis | 1992 |
Variant protein patterns in hepatomas and transformed liver cell lines as determined by high resolution two-dimensional gel electrophoresis (2DE).
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosamine; Electropho | 1992 |
Lack of effects of viral sialoadenitis and depletion of epidermal growth factor on initiation of hepatic carcinogenesis in the rat.
Topics: Animals; Antibodies, Viral; Cell Transformation, Neoplastic; Coronaviridae; Coronaviridae Infections | 1991 |
Effects of polychlorinated biphenyls in rat liver: quantitative analysis of enzyme-altered foci.
Topics: Adenosine Triphosphatases; Animals; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Diet | 1991 |
Strain A/J mouse lung adenoma growth patterns vary when induced by different carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenoma; Aflatoxins; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformatio | 1991 |
gamma-Glutamyltranspeptidase-positive rat hepatocytes are protected from GSH depletion, oxidative stress and reversible alterations of collagen receptors.
Topics: Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cells, Cultured; Collagen; Diethylnitro | 1990 |
Antigenic relationship between oval cells and a subpopulation of hepatic foci, nodules, and carcinomas induced by the "resistant hepatocyte" model system.
Topics: Animals; Antibodies, Monoclonal; Antigens; Cell Transformation, Neoplastic; Diethylnitrosamine; Dise | 1991 |
Liver tumor promotion: effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-beta 1 expression.
Topics: Animals; Binding, Competitive; Cell Transformation, Neoplastic; Diethylnitrosamine; Epidermal Growth | 1991 |
Nuclear DNA content of altered hepatic foci in a rat liver carcinogenesis model.
Topics: Aneuploidy; Animals; Cell Nucleus; Cell Transformation, Neoplastic; Choline; Diethylnitrosamine; Dis | 1990 |
Increased silver stainability of metaphase chromosomes from rat hepatocytes during in vivo hepatocarcinogenesis.
Topics: Animals; Cell Transformation, Neoplastic; Chromosomes; Diethylnitrosamine; Liver Neoplasms; Metaphas | 1985 |
In situ hybridization studies on expression of albumin and alpha-fetoprotein during the early stage of neoplastic transformation in rat liver.
Topics: Albumins; alpha-Fetoproteins; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Gene Exp | 1987 |
Expression of N-acetylglucosaminyltransferase III in hepatic nodules generated by different models of rat liver carcinogenesis.
Topics: Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Glucosyltransferases; Intracellular Me | 1989 |
[Early stages of hepatic carcinogenesis after vagotomy].
Topics: Adenosine Triphosphatases; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Enzyme Acti | 1989 |
Tumor phenotype and susceptibility to progression as an expression of subpopulations of initiated murine cells.
Topics: alpha-Fetoproteins; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Disease Susceptibi | 1985 |
Ethanol treatment inhibits the development of diethylnitrosamine-induced tumors in rats.
Topics: Animals; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme | 1989 |
Detection of activated proto-oncogenes in N-nitrosodiethylamine-induced liver tumors: a comparison between B6C3F1 mice and Fischer 344 rats.
Topics: Animals; Cell Transformation, Neoplastic; Codon; Diethylnitrosamine; DNA Restriction Enzymes; DNA, N | 1988 |
Reduced autophagic activity, improved protein balance and enhanced in vitro survival of hepatocytes isolated from carcinogen-treated rats.
Topics: 2-Acetylaminofluorene; Adenine; Adenosine Triphosphatases; Amino Acids; Animals; Autophagy; Carcinog | 1985 |
Molecular dosimetry of DNA alkylation during chronic exposure to carcinogens.
Topics: Alkylation; Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; DNA; Dose-Res | 1987 |
Expression of the cytosolic and particulate forms of transglutaminase during chemically induced rat liver carcinogenesis.
Topics: Animals; Carcinoma; Cell Transformation, Neoplastic; Cell-Free System; Cytosol; Diethylnitrosamine; | 1988 |
beta-Carotene reduces sister chromatid exchanges induced by chemical carcinogens in mouse mammary cells in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carcinogens; Carotenoids; Cell Transformat | 1985 |
Analysis of the interlaboratory and intralaboratory reproducibility of the enhancement of simian adenovirus SA7 transformation of Syrian hamster embryo cells by model carcinogenic and noncarcinogenic compounds.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Adenoviridae; Ade | 1986 |
Resistance to oxidative stress by hyperplastic and neoplastic rat liver tissue monitored in terms of production of unpolar and medium polar carbonyls.
Topics: Aldehydes; Animals; Arachidonic Acid; Arachidonic Acids; Cell Transformation, Neoplastic; Chromatogr | 1986 |
A method for the amplification of chemically induced transformation in C3H/10T1/2 clone 8 cells: its use as a potential screening assay.
Topics: 2-Naphthylamine; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cell Transformat | 1987 |
Increased expression of the N-myc gene during normal and neoplastic rat liver growth.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Diethylnitrosamine; Female; Kinetics; Liver | 1988 |
Increased hepatic androgen receptor expression in female rats during diethylnitrosamine liver carcinogenesis. A possible correlation with liver tumor development.
Topics: Animals; Binding, Competitive; Cell Transformation, Neoplastic; Diethylnitrosamine; Female; Isoelect | 1988 |
The studies of malignant transformation of human epithelial cells induced by diethyl-nitrosamine (NDEA) in vitro.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosamine; Epithelial Cells; Fet | 1986 |
Malignant transformation of human fetal lung fibroblasts induced by nitrosamine compounds in vitro.
Topics: Cell Transformation, Neoplastic; Diethylnitrosamine; Fetus; Fibroblasts; Humans; Karyotyping; Lung N | 1986 |
Tumor-initiating and promoting activities of di(2-ethylhexyl) phthalate in vivo and in vitro.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; Diethylh | 1986 |
Organ specific modifying potential of ethinyl estradiol on carcinogenesis initiated with different carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Interactio | 1987 |
Promoting effect of oxazepam in rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Diethylnitrosamin | 1987 |
Use of rodent hepatocytes for metabolic activation in transformation assays.
Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cell Cycle; Cell L | 1985 |
Changes in polypeptide pattern of rat liver cells during chemical hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Aging; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Liver; L | 1985 |
Nucleolar changes during the first steps of experimental hepatocarcinogenesis in rats.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Nucleolus; Cell Transformation, Neoplasti | 1985 |
Growth inhibition and transformation of a human fetal tracheal epithelial cell line by long-term exposure to diethylnitrosamine.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chick Embryo; Diethylnitrosamine; DNA Repair; E | 1985 |
12-O-Tetradecanoylphorbol-13-acetate promotion of carcinogen-treated rat liver endothelial cells.
Topics: Animals; Benzo(a)pyrene; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Diethylnitros | 1985 |