diethylnitrosamine has been researched along with Cancer of Lung in 152 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to evaluate the anti-cancer effect of neferine against diethylnitrosamine (DEN)-induced lung carcinogenesis in Wistar rats and to explore the underlying molecular mechanism." | 7.91 | Neferine suppresses diethylnitrosamine-induced lung carcinogenesis in Wistar rats. ( Amirthalingam, V; Ganasan, K; Huang, CY; Sivalingam, K; Viswanadha, VP, 2019) |
| "We established a new lung adenocarcinoma model using FVB/N mouse strain and diethylnitrosamine." | 7.88 | Diethylnitrosamine induces lung adenocarcinoma in FVB/N mouse. ( Baghy, K; Egedi, K; Kovalszky, I; Mervai, Z, 2018) |
| " In the present study, we set up a rat model of diethylnitrosamine (DEN) induced pulmonary adenoma to evaluate the antitumor effects of RPS again." | 7.81 | Inhibition of pulmonary adenoma in diethylnitrosamine-induced rats by Rhizoma paridis saponins. ( Chai, H; Fan, W; Gao, W; Li, J; Liu, Z; Man, S, 2015) |
| "The promoting effect of NaCl solution mist was studied in the induction of papillomas on Syrian hamster trachea following single subcutaneous injection of diethylnitrosamine (DEN)." | 7.68 | Promoting effect of sodium chloride solution mist on the induction of papillomas on Syrian hamster tracheal mucosa following administration of diethylnitrosamine. ( Karube, T; Katayama, H; Takemoto, K; Watanabe, S, 1991) |
| "Incidences of lung metastasis in the 40 ppm group steadily increased up to 67% by week 36 while that in the 80 ppm increased sharply up to 86% by week 24." | 5.33 | Modification of an in vivo lung metastasis model of hepatocellular carcinoma by low dose N-nitrosomorpholine and diethylnitrosamine. ( Cho, YM; Futakuchi, M; Imai, N; Ogawa, K; Shirai, T; Takeshita, F; Tamano, S; Yoshino, H, 2005) |
| " The aim of this study was to evaluate the anti-cancer effect of neferine against diethylnitrosamine (DEN)-induced lung carcinogenesis in Wistar rats and to explore the underlying molecular mechanism." | 3.91 | Neferine suppresses diethylnitrosamine-induced lung carcinogenesis in Wistar rats. ( Amirthalingam, V; Ganasan, K; Huang, CY; Sivalingam, K; Viswanadha, VP, 2019) |
| "We established a new lung adenocarcinoma model using FVB/N mouse strain and diethylnitrosamine." | 3.88 | Diethylnitrosamine induces lung adenocarcinoma in FVB/N mouse. ( Baghy, K; Egedi, K; Kovalszky, I; Mervai, Z, 2018) |
| " In the present study, we set up a rat model of diethylnitrosamine (DEN) induced pulmonary adenoma to evaluate the antitumor effects of RPS again." | 3.81 | Inhibition of pulmonary adenoma in diethylnitrosamine-induced rats by Rhizoma paridis saponins. ( Chai, H; Fan, W; Gao, W; Li, J; Liu, Z; Man, S, 2015) |
| "We previously found by chance that N-nitrosomorpholine (NMOR) given after a multi-carcinogenic treatment induces liver carcinomas with 56% lung metastasis, and it was confirmed that hepatocellular carcinoma (HCC) with 100% lung metastasis was produced by 24-week treatment with NMOR and additional treatment with diethylnitrosamine (DEN)." | 3.70 | Establishment of an in vivo highly metastatic rat hepatocellular carcinoma model. ( Futakuchi, M; Hirose, M; Kato, K; Ogawa, K; Ogiso, T; Sano, M; Shirai, T, 1999) |
| "A CK immunohistochemical study was carried out on histologic sections from hepatocellular carcinomas (HCCs) and preneoplastic lesions from 118 monkeys chronically dosed with diethylnitrosamine (DEN), using mAbs to CK 8, CK 18, CK 7, and CK 19." | 3.69 | Cytokeratin patterns of liver carcinomas induced by diethylnitrosamine in monkeys. ( Bocsi, J; Lapis, K; Sarosi, I; Thorgeirsson, UP, 1995) |
| "The promoting effect of NaCl solution mist was studied in the induction of papillomas on Syrian hamster trachea following single subcutaneous injection of diethylnitrosamine (DEN)." | 3.68 | Promoting effect of sodium chloride solution mist on the induction of papillomas on Syrian hamster tracheal mucosa following administration of diethylnitrosamine. ( Karube, T; Katayama, H; Takemoto, K; Watanabe, S, 1991) |
| " Two types of areas composed of basophilic or glycogenotic hepatocytes were observed preceding the appearance of hepatocellular adenomas and carcinomas." | 3.68 | Rat hepatocarcinogenesis induced by N-nitrosodiethylamine and N-nitrosomorpholine continuously administered at low doses. From basophilic areas of hepatocytes to hepatocellular tumors. ( Cortinovis, C; Klimek, F; Nogueira, E, 1991) |
| "In a study on lung adenomas induced by the administration of a single intragastric dose of sodium thiocyanate, diethylnitrosamine, or its precursors to 15-day-old C57BLxC3H F1 mice the occurrence of crystalline inclusions in pulmonary parenchyma was noted." | 3.67 | Crystalline inclusions associated with lung adenomas in C57BLxC3H F1 mice. ( Abrahams, C; Ghose, T; Rijhsinghani, KS; Swerdlow, MA, 1988) |
| "The frequency of metastases of malignant diethylnitrosamine-induced hepatomas and haemangioendotheliomas of the liver of female Sprague-Dawley rats (29%) was not influenced by application of acetyl-salicylic acid or phenprocoumon." | 3.65 | [Studies on the influence of anticoagulants on metastase formation of autochthonic hepatomas in the rat (author's transl)]. ( Schmähl, D, 1975) |
| " The non-toxic dosage of eugenol was shown to enhance apoptosis, simultaneously suppressing cell proliferation in the lung tissue of carcinogen-treated mice without affecting the normal mice." | 1.62 | Eugenol emerges as an elixir by targeting β-catenin, the central cancer stem cell regulator in lung carcinogenesis: an ( Barua, A; Bhattacharyya, M; Choudhury, P; Pattanayak, R; Roy, A; Saha, P, 2021) |
| "Lung cancer is the foremost cause of cancer mortality and a growing economic burden worldwide." | 1.46 | Inhibition of lung cancer in diethylnitrosamine-induced mice by Rhizoma paridis saponins. ( Gao, W; Li, J; Liu, J; Liu, Z; Ma, L; Man, S; Qiu, P, 2017) |
| " These results provide a rationale for long-term MET dosing in future clinical trials of HCC treatment." | 1.37 | Suppression of hepatic tumor growth and metastasis by metronomic therapy in a rat model of hepatocellular carcinoma. ( Bae, SH; Choi, JY; Jang, JW; Jung, CK; Kwon, JH; Park, ST; Yoon, SK; You, CR, 2011) |
| "In the liver cirrhosis and liver cancer group, Mphi had more prominences, meanwhile much more mitochondria, ribosome, rough endoplasmic reticulum, lysosome can be found in the cytoplasm, especially in the liver cancer group." | 1.35 | Changes of splenic macrophage during the process of liver cancer induced by diethylnitrosamine in rats. ( Huang, C; Li, ZF; Liu, ZW; Pan, D; Zhang, S; Zhou, R, 2009) |
| " PB produced a twofold increase in liver MF over controls after 27 weeks of treatment, but a similar increase was not observed with longer dosing times; at later time points, the MF in the PB groups was lower than that of the control group, suggesting that PB is not producing direct DNA damage in the liver." | 1.33 | Evaluation of mutant frequencies of chemically induced tumors and normal tissues in lambda/cII transgenic mice. ( de Boer, J; Fairchild, D; Glickman, B; Johnson, A; Kanazawa, N; Mirsalis, JC; Nguyen, T; Shimon, JA; Winegar, RA, 2005) |
| "Incidences of lung metastasis in the 40 ppm group steadily increased up to 67% by week 36 while that in the 80 ppm increased sharply up to 86% by week 24." | 1.33 | Modification of an in vivo lung metastasis model of hepatocellular carcinoma by low dose N-nitrosomorpholine and diethylnitrosamine. ( Cho, YM; Futakuchi, M; Imai, N; Ogawa, K; Shirai, T; Takeshita, F; Tamano, S; Yoshino, H, 2005) |
| "Although no lung metastasis was observed in the rats killed at the end of the period of carcinogen exposure, lung metastasis was found in 100% of animals in all the groups at the end of the experiment." | 1.32 | Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma. ( Futakuchi, M; Ogawa, K; Shirai, T; Takahashi, S; Tamano, S, 2004) |
| "Ellagic acid was able to significantly reduce tumour incidence to 20% from the control value of 72." | 1.30 | Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice. ( Gandhi, RK; Khanduja, KL; Pathania, V; Syal, N, 1999) |
| "Our studies and others have shown the cancer chemopreventive effects of chronic administration of green tea in several animal tumor models." | 1.29 | Protective effects of green tea polyphenols administered by oral intubation against chemical carcinogen-induced forestomach and pulmonary neoplasia in A/J mice. ( Agarwal, R; Katiyar, SK; Mukhtar, H, 1993) |
| " The inhibitory effects of green tea infusion were also observed in a similar experiment using a higher dosage of NDEA (20 mg/kg)." | 1.28 | Inhibition of N-nitrosodiethylamine- and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorigenesis in A/J mice by green tea and black tea. ( Conney, AH; Hong, JY; Huang, MT; Reuhl, KR; Wang, ZY; Yang, CS, 1992) |
| "The dose-response of diethylnitrosamine (DENA) initiation of hepatocarcinogenesis was determined in infant Balb/c male mice with and without subsequent phenobarbital treatment." | 1.27 | Dose-response relationship of diethylnitrosamine-initiated tumors in neonatal balb/c mice: effect of phenobarbital promotion. ( Klaunig, JE; Pereira, MA; Ruch, RJ; Weghorst, CM, 1988) |
| " These results indicate that, when administered by this route, NDEA is a much more potent carcinogen in the respiratory tract than is NDMA but NDMA alone seems to be carcinogenic to the liver, at a total dosage of 1." | 1.27 | A comparison of the carcinogenicity of N-nitrosodiethylamine and N-nitrosodimethylamine after intratracheal instillation into Syrian golden hamsters. ( Hirata, M; Hisanaga, A; Inamasu, T; Ishinishi, N; Tanaka, A, 1988) |
| "Neuroendocrine lung cancer is among the most common types of lung tumor in man and demonstrates a strong etiological association with cigarette smoking." | 1.27 | An animal model for neuroendocrine lung cancer. ( Becker, KL; Schuller, HM; Witschi, HP, 1988) |
| "Choline was not effective in inhibiting the development of lung metastases in either case." | 1.27 | Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats. ( Hoover, KL; Poirier, LA; Shivapurkar, N, 1986) |
| " DMN induced a considerable quantity of liver tumours, the highest incidence being demonstrated in the lowest dosage group." | 1.26 | Carcinogenic effects of different nitroso-compounds in Chinese hamsters. I. Dimethylnitrosamine and N-diethylnitrosamine. ( Kmoch, N; Mohr, U; Reznik, G, 1976) |
| "The pulmonary metastases were first detected in mice dying between 51 and 60 weeks of age (5%)." | 1.26 | Morphology and metastatic nature of induced hepatic nodular lesions in C57BL x C3H F1 mice. ( Mihailovich, N; Rao, KV; Vesselinovitch, SD, 1978) |
| " However, the hibernating females of the low dosage group developed fewer lung tumors." | 1.26 | Carcinogenicity of N-nitrosodiethylamine in hibernating and nonhibernating European hamsters. ( Mohr, U; Reznik, G; Reznik-Schüller, R, 1977) |
| " It was pointed out that the direct measurement of the dose-response relation (l(d) approximately dm) yields only the number of hits contributed by the carcinogen applied anose rate is low or very low, the contribution of background process becomes significant, and these hits contribute to the power of time, r, of the incidence-time relation." | 1.26 | Multi-hit kinetics of tumor formation, with special reference to experimental liver and human lung carcinogenesis and some gneral conclusions. ( Emmelot, P; Scherer, E, 1977) |
| "Fe2O3 caused pulmonary fibrosis and synthetic smog caused alveolar bronchiolization in many of the exposed animals." | 1.25 | Carcinogenic and cocarcinogenic effects of inhaled synthetic smog and ferric oxide particles. ( Creasia, DA; Mitchell, TJ; Nettesheim, P, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 69 (45.39) | 18.7374 |
| 1990's | 44 (28.95) | 18.2507 |
| 2000's | 18 (11.84) | 29.6817 |
| 2010's | 16 (10.53) | 24.3611 |
| 2020's | 5 (3.29) | 2.80 |
| Authors | Studies |
|---|---|
| Li, M | 1 |
| Li, X | 1 |
| Goldsmith, JR | 1 |
| Shi, S | 1 |
| Zhang, L | 1 |
| Zamani, A | 1 |
| Wan, L | 1 |
| Sun, H | 1 |
| Li, T | 1 |
| Yu, J | 1 |
| Etwebi, Z | 1 |
| Bou-Dargham, MJ | 1 |
| Chen, YH | 1 |
| Dong, Z | 1 |
| Gu, W | 1 |
| Xu, L | 1 |
| Morsy, HM | 1 |
| Ahmed, OM | 2 |
| Zoheir, KMA | 1 |
| Abdel-Moneim, A | 2 |
| Choudhury, P | 1 |
| Barua, A | 1 |
| Roy, A | 1 |
| Pattanayak, R | 1 |
| Bhattacharyya, M | 1 |
| Saha, P | 1 |
| Abd El-Twab, SM | 1 |
| Zaky, MY | 1 |
| Bakry, LN | 1 |
| Mervai, Z | 1 |
| Egedi, K | 1 |
| Kovalszky, I | 1 |
| Baghy, K | 1 |
| Sivalingam, K | 1 |
| Amirthalingam, V | 1 |
| Ganasan, K | 1 |
| Huang, CY | 1 |
| Viswanadha, VP | 1 |
| Kanellakis, NI | 1 |
| Giannou, AD | 1 |
| Pepe, MAA | 1 |
| Agalioti, T | 1 |
| Zazara, DE | 1 |
| Giopanou, I | 1 |
| Psallidas, I | 1 |
| Spella, M | 1 |
| Marazioti, A | 1 |
| Arendt, KAM | 1 |
| Lamort, AS | 1 |
| Champeris Tsaniras, S | 1 |
| Taraviras, S | 1 |
| Papadaki, H | 1 |
| Lilis, I | 1 |
| Stathopoulos, GT | 1 |
| Kojima, A | 1 |
| Horiguchi, N | 1 |
| Kakizaki, S | 1 |
| Takayama, H | 1 |
| Mori, M | 2 |
| Man, S | 2 |
| Li, J | 2 |
| Fan, W | 1 |
| Chai, H | 1 |
| Liu, Z | 2 |
| Gao, W | 2 |
| Qiu, P | 1 |
| Liu, J | 1 |
| Ma, L | 1 |
| Iatropoulos, MJ | 1 |
| Cerven, DR | 1 |
| de George, G | 1 |
| von Keutz, E | 1 |
| Williams, GM | 1 |
| Liu, WB | 5 |
| Liu, JY | 4 |
| Ao, L | 4 |
| Zhou, ZY | 4 |
| Zhou, YH | 4 |
| Cui, ZH | 4 |
| Yang, H | 1 |
| Cao, J | 5 |
| Roy, P | 1 |
| Nigam, N | 1 |
| Singh, M | 1 |
| George, J | 1 |
| Srivastava, S | 1 |
| Naqvi, H | 1 |
| Shukla, Y | 2 |
| Kaledin, VI | 3 |
| Il'nitskaia, SI | 3 |
| Baginskaia, NV | 3 |
| Sen'kova, AV | 1 |
| Zhang, S | 2 |
| Li, ZF | 2 |
| Pan, D | 2 |
| Huang, C | 2 |
| Zhou, R | 2 |
| Liu, ZW | 1 |
| Wang, J | 1 |
| Yang, J | 1 |
| Jiang, A | 1 |
| Yuan, XY | 2 |
| Xiang, YL | 2 |
| Wang, YC | 1 |
| Xu, GL | 1 |
| Jia, WD | 1 |
| Han, SJ | 1 |
| Ren, WH | 1 |
| Wang, W | 1 |
| Zhang, CH | 1 |
| Chen, H | 2 |
| Jang, JW | 1 |
| Park, ST | 1 |
| Kwon, JH | 1 |
| You, CR | 1 |
| Choi, JY | 1 |
| Jung, CK | 1 |
| Bae, SH | 1 |
| Yoon, SK | 1 |
| Thuy, le TT | 1 |
| Morita, T | 1 |
| Yoshida, K | 1 |
| Wakasa, K | 1 |
| Iizuka, M | 1 |
| Ogawa, T | 1 |
| Sekiya, Y | 1 |
| Momen, S | 1 |
| Motoyama, H | 1 |
| Ikeda, K | 1 |
| Yoshizato, K | 1 |
| Kawada, N | 1 |
| Luo, D | 1 |
| Liu, D | 1 |
| Zhou, X | 1 |
| Yang, S | 1 |
| Tang, C | 1 |
| Liu, G | 1 |
| Yamagishi, M | 1 |
| Natsume, M | 1 |
| Osakabe, N | 1 |
| Okazaki, K | 2 |
| Furukawa, F | 1 |
| Imazawa, T | 2 |
| Nishikawa, A | 3 |
| Hirose, M | 7 |
| DONTENWILL, W | 1 |
| MOHR, U | 3 |
| ZAGEL, M | 1 |
| ARGUS, MF | 1 |
| HOCH-LIGETI, C | 1 |
| RAPP, HJ | 1 |
| CARLETON, JH | 1 |
| CRISLER, C | 1 |
| NADEL, EM | 1 |
| TAKAYAMA, S | 1 |
| OOTA, K | 1 |
| Futakuchi, M | 3 |
| Ogawa, K | 3 |
| Tamano, S | 2 |
| Takahashi, S | 1 |
| Shirai, T | 6 |
| King, TJ | 1 |
| Lampe, PD | 1 |
| Mirsalis, JC | 1 |
| Shimon, JA | 1 |
| Johnson, A | 1 |
| Fairchild, D | 1 |
| Kanazawa, N | 1 |
| Nguyen, T | 1 |
| de Boer, J | 1 |
| Glickman, B | 1 |
| Winegar, RA | 1 |
| Boissan, M | 1 |
| Wendum, D | 1 |
| Arnaud-Dabernat, S | 1 |
| Munier, A | 1 |
| Debray, M | 1 |
| Lascu, I | 1 |
| Daniel, JY | 1 |
| Lacombe, ML | 1 |
| Yoshino, H | 1 |
| Cho, YM | 1 |
| Takeshita, F | 1 |
| Imai, N | 1 |
| Kitamura, Y | 1 |
| Umemura, T | 2 |
| Kanki, K | 2 |
| Masegi, T | 1 |
| Kodama, Y | 1 |
| Hioki, K | 1 |
| Nomura, T | 1 |
| Kuroiwa, Y | 1 |
| Ishii, Y | 1 |
| Kurokawa, Y | 1 |
| Kholodar', AV | 1 |
| Obut, TA | 1 |
| Naura, AS | 1 |
| Kalla, NR | 1 |
| Sharma, RP | 1 |
| Sharma, R | 1 |
| Gould, VE | 2 |
| Linnoila, RI | 2 |
| Memoli, VA | 1 |
| Warren, WH | 1 |
| Tian, HS | 1 |
| Liu, MQ | 1 |
| Gao, WQ | 1 |
| Zuo, RD | 1 |
| Xiong, YY | 1 |
| Chen, ZF | 1 |
| Diwan, BA | 9 |
| Rice, JM | 5 |
| Ward, JM | 7 |
| Ohshima, M | 1 |
| Lynch, PH | 1 |
| Vesselinovitch, SD | 2 |
| Koka, M | 1 |
| Mihailovich, N | 2 |
| Rao, KV | 5 |
| Newberne, PM | 1 |
| Connor, M | 1 |
| Lijinsky, W | 2 |
| Clapp, NK | 2 |
| Perkins, EH | 1 |
| Klima, WC | 2 |
| Cacheiro, LH | 1 |
| Marxer, A | 1 |
| Schmidt-Ruppin, KH | 2 |
| Rijhsinghani, KS | 2 |
| Krakower, C | 1 |
| Abrahams, C | 2 |
| Swerdlow, M | 1 |
| Ghose, T | 2 |
| Iversen, OH | 1 |
| Luo, DY | 1 |
| Bai, SH | 1 |
| Wang, CJ | 1 |
| Lapis, K | 4 |
| Sarosi, I | 1 |
| Bocsi, J | 3 |
| Thorgeirsson, UP | 4 |
| Beebe, LE | 1 |
| Fornwald, LW | 1 |
| Anver, MR | 1 |
| Anderson, LM | 3 |
| Akagi, K | 1 |
| Hoshiya, T | 1 |
| Mizoguchi, Y | 1 |
| Ito, N | 3 |
| Lapis, P | 2 |
| Li, ZQ | 1 |
| Witschi, H | 3 |
| Breider, MA | 1 |
| Schuller, HM | 10 |
| Katiyar, SK | 2 |
| Agarwal, R | 3 |
| Mukhtar, H | 3 |
| Henneman, JR | 2 |
| Nims, RW | 1 |
| Chen, B | 1 |
| Liu, L | 1 |
| Castonguay, A | 2 |
| Maronpot, RR | 1 |
| Anderson, MW | 2 |
| You, M | 2 |
| Waalkes, MP | 2 |
| Weghorst, CM | 3 |
| Cherian, MG | 1 |
| Goyer, RA | 1 |
| Carter, JP | 1 |
| Driver, CL | 1 |
| Logsdon, DL | 1 |
| Kovatch, RM | 3 |
| Giner-Sorolla, A | 1 |
| Wilson, DW | 1 |
| Plopper, CG | 1 |
| Zaim, MT | 1 |
| Zalatnai, A | 1 |
| Timár, F | 2 |
| Xu, Y | 1 |
| Chen, J | 1 |
| Klaunig, JE | 2 |
| Giri, RK | 1 |
| Baral, RN | 1 |
| Das, BR | 1 |
| Takaba, K | 1 |
| Yoshida, Y | 1 |
| Kimura, J | 1 |
| La Porta, CA | 1 |
| Tessitore, L | 1 |
| Comolli, R | 1 |
| Willett, CG | 3 |
| Smith, DI | 1 |
| Shridhar, V | 1 |
| Wang, MH | 1 |
| Emanuel, RL | 1 |
| Patidar, K | 1 |
| Graham, SA | 1 |
| Zhang, F | 1 |
| Hatch, V | 1 |
| Sugarbaker, DJ | 1 |
| Sunday, ME | 3 |
| Kim, DJ | 2 |
| Takasuka, N | 2 |
| Kim, JM | 1 |
| Sekine, K | 1 |
| Ota, T | 1 |
| Asamoto, M | 1 |
| Murakoshi, M | 1 |
| Nishino, H | 2 |
| Nir, Z | 1 |
| Tsuda, H | 3 |
| Shiota, G | 1 |
| Harada, K | 1 |
| Ishida, M | 1 |
| Tomie, Y | 1 |
| Okubo, M | 1 |
| Katayama, S | 1 |
| Ito, H | 1 |
| Kawasaki, H | 1 |
| Khanduja, KL | 2 |
| Gandhi, RK | 2 |
| Pathania, V | 1 |
| Syal, N | 1 |
| Tomasi, C | 1 |
| Laconi, E | 1 |
| Laconi, S | 1 |
| Greco, M | 1 |
| Sarma, DS | 1 |
| Pani, P | 1 |
| Ogiso, T | 2 |
| Kato, K | 1 |
| Sano, M | 1 |
| Taneja, P | 1 |
| Diao, L | 1 |
| Chen, D | 1 |
| Li, H | 1 |
| Liu, M | 1 |
| Hashimoto, S | 1 |
| Sueishi, K | 1 |
| Reznik-Schüller, H | 4 |
| Craddock, VM | 1 |
| Schmähl, D | 1 |
| Thust, R | 2 |
| Warzok, R | 1 |
| Fridman-Manduzio, A | 1 |
| Gol-Winkler, R | 1 |
| Betz, EH | 1 |
| Goutier, R | 1 |
| Pottathil, R | 1 |
| Huebner, RJ | 1 |
| Meier, H | 3 |
| Tyndall, RL | 1 |
| Satterfield, LC | 1 |
| Bowles, ND | 1 |
| Sula, J | 1 |
| Katsuta, H | 1 |
| Takaoka, T | 1 |
| Wehner, AP | 1 |
| Stuart, BO | 1 |
| Sanders, CL | 1 |
| Reznik, G | 3 |
| Reznik-Schüller, R | 1 |
| Worzok, R | 1 |
| Emmelot, P | 1 |
| Scherer, E | 1 |
| Papadopulu, G | 1 |
| Nettesheim, P | 1 |
| Creasia, DA | 1 |
| Mitchell, TJ | 1 |
| Spit, BJ | 1 |
| Feron, VJ | 1 |
| Kmoch, N | 1 |
| Moon, RC | 2 |
| Detrisac, CJ | 2 |
| Kelloff, GJ | 2 |
| Wang, Y | 1 |
| Lineen, AM | 1 |
| Gunning, WT | 2 |
| Stoner, GD | 2 |
| Lee, YS | 2 |
| Seo, JS | 1 |
| Chung, HT | 1 |
| Cho, KJ | 2 |
| Jan, JJ | 1 |
| Wang, ZY | 2 |
| Khan, WA | 1 |
| Manam, S | 1 |
| Storer, RD | 1 |
| Prahalada, S | 1 |
| Leander, KR | 1 |
| Kraynak, AR | 1 |
| Hammermeister, CL | 1 |
| Joslyn, DJ | 1 |
| Ledwith, BJ | 1 |
| van Zwieten, MJ | 1 |
| Bradley, MO | 1 |
| Koul, IB | 1 |
| Sehgal, S | 1 |
| Sharma, RR | 1 |
| Hong, JY | 1 |
| Huang, MT | 1 |
| Reuhl, KR | 1 |
| Conney, AH | 1 |
| Yang, CS | 1 |
| Ning, H | 1 |
| Oreffo, VI | 1 |
| Gumerlock, PH | 1 |
| Goldblatt, PJ | 1 |
| Jang, JJ | 1 |
| Bae, JH | 1 |
| Bare, RM | 1 |
| Karube, T | 1 |
| Katayama, H | 1 |
| Takemoto, K | 1 |
| Watanabe, S | 1 |
| Cortinovis, C | 1 |
| Klimek, F | 1 |
| Nogueira, E | 1 |
| Correa, E | 1 |
| Orloff, M | 1 |
| Reznik, GK | 1 |
| Nylen, ES | 1 |
| Becker, KL | 2 |
| Joshi, PA | 1 |
| Snider, RH | 1 |
| Swerdlow, MA | 1 |
| Rehm, S | 1 |
| Takahashi, M | 1 |
| Singh, G | 2 |
| Katyal, SL | 2 |
| Brightwell, J | 1 |
| Fouillet, X | 1 |
| Cassano-Zoppi, AL | 1 |
| Bernstein, D | 1 |
| Crawley, F | 1 |
| Duchosal, F | 1 |
| Gatz, R | 1 |
| Perczel, S | 1 |
| Pfeifer, H | 1 |
| Huntrakoon, M | 1 |
| Menon, CD | 1 |
| Hung, KS | 1 |
| Kakizoe, S | 1 |
| Goldfarb, S | 1 |
| Pugh, TD | 1 |
| Hecht, SS | 1 |
| Chung, FL | 1 |
| Saavedra, JE | 1 |
| Hegedus, TJ | 1 |
| Falzon, M | 3 |
| Margaretten, N | 1 |
| Gazdar, AF | 3 |
| Hegedus, T | 1 |
| Zhang, ZJ | 1 |
| Gao, FM | 1 |
| Yu, YN | 1 |
| McMahon, JB | 1 |
| Ito, T | 1 |
| Kitamura, H | 1 |
| Inayama, Y | 1 |
| Kanisawa, M | 1 |
| Hagiwara, A | 1 |
| Pereira, MA | 1 |
| Ruch, RJ | 1 |
| Tanaka, A | 1 |
| Hisanaga, A | 2 |
| Inamasu, T | 1 |
| Hirata, M | 1 |
| Ishinishi, N | 2 |
| Witschi, HP | 1 |
| Huang, M | 1 |
| Wang, ZH | 1 |
| Wang, XQ | 1 |
| Wu, M | 1 |
| Du, ZM | 1 |
| Wattenberg, LW | 2 |
| Shivapurkar, N | 1 |
| Hoover, KL | 1 |
| Poirier, LA | 1 |
| Bueding, E | 1 |
| Yamamoto, A | 1 |
| Becker, RA | 1 |
| Shank, RC | 1 |
| Wilhelmsson, B | 1 |
| Lundh, B | 1 |
| Drettner, B | 1 |
7 reviews available for diethylnitrosamine and Cancer of Lung
| Article | Year |
|---|---|
Neuroendocrine cells and neuroendocrine neoplasms of the lung.
Topics: Adenocarcinoma; Animals; APUD Cells; Bronchi; Carcinoma, Adenoid Cystic; Carcinoma, Small Cell; Cric | 1983 |
[Basic research on lung cancer].
Topics: Animals; Diethylnitrosamine; Disease Models, Animal; Genes, Tumor Suppressor; Growth Substances; His | 2002 |
Sequential morphologic alterations in the bronchial epithelium of Syrian golden hamsters during N-nitrosomorpholine-induced pulmonary tumorigenesis.
Topics: Animals; APUD Cells; Bronchi; Cricetinae; Diethylnitrosamine; Epithelium; Inclusion Bodies; Lung Neo | 1977 |
Experimental data concerning the question of the synergic action of the influenza virus and of some chemical carcinogens in the pathogenesis of lung cancer.
Topics: Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Humans; Influenza, Human; Lung Neoplasms | 1979 |
Nitrosamine-induced lung carcinogenesis and Ca2+/calmodulin antagonists.
Topics: Animals; Calcium; Calmodulin; Carcinogens; Diethylnitrosamine; Lung; Lung Neoplasms; Neoplasms, Nerv | 1992 |
Hamster lung cancer model of carcinogenesis and chemoprevention.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Cricetinae; Diethylnitrosamine; Lung Neop | 1992 |
Small cell cancer of the lung. The role of unphysiological pulmonary oxygen levels.
Topics: Animals; Carcinoma, Small Cell; Diethylnitrosamine; Humans; Lung Neoplasms; Neurosecretory Systems; | 1988 |
145 other studies available for diethylnitrosamine and Cancer of Lung
| Article | Year |
|---|---|
Decoupling tumor cell metastasis from growth by cellular pilot protein TNFAIP8.
Topics: Animals; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diethyl | 2021 |
Exploring the mechanism of miR320a in regulating PDL1 upon lung cancer pathogenesis.
Topics: Animals; B7-H1 Antigen; Biomarkers, Tumor; Carcinogens; Diethylnitrosamine; Lung Neoplasms; Male; Mi | 2022 |
The anticarcinogenic effect of eugenol on lung cancer induced by diethylnitrosamine/2-acetylaminofluorene in Wistar rats: insight on the mechanisms of action.
Topics: 2-Acetylaminofluorene; Animals; Anticarcinogenic Agents; Apoptosis; Diethylnitrosamine; Eugenol; Liv | 2023 |
Eugenol emerges as an elixir by targeting β-catenin, the central cancer stem cell regulator in lung carcinogenesis: an
Topics: A549 Cells; Animals; Apoptosis; beta Catenin; Diethylnitrosamine; Eugenol; Female; Gene Expression R | 2021 |
Prophylactic effects of Cynara scolymus L. leaf and flower hydroethanolic extracts against diethylnitrosamine/acetylaminoflourene-induced lung cancer in Wistar rats.
Topics: Animals; Cynara scolymus; Diethylnitrosamine; Flowers; Liver; Lung Neoplasms; Oxidative Stress; Plan | 2021 |
Diethylnitrosamine induces lung adenocarcinoma in FVB/N mouse.
Topics: Adenocarcinoma; Animals; Base Sequence; Biomarkers, Tumor; Diethylnitrosamine; Disease Models, Anima | 2018 |
Neferine suppresses diethylnitrosamine-induced lung carcinogenesis in Wistar rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzylisoquinolines; Carcinogenesis; Diethyln | 2019 |
Tobacco chemical-induced mouse lung adenocarcinoma cell lines pin the prolactin orthologue proliferin as a lung tumour promoter.
Topics: Adenocarcinoma of Lung; Animals; Carcinogenesis; Carcinogens; Cell Line, Tumor; Diethylnitrosamine; | 2019 |
Hepatocyte growth factor promotes lung carcinogenesis in transgenic mice treated with diethylnitrosamine.
Topics: Animals; Diethylnitrosamine; Female; Hepatocyte Growth Factor; Lung Neoplasms; Male; Mice; Mice, Tra | 2013 |
Inhibition of pulmonary adenoma in diethylnitrosamine-induced rats by Rhizoma paridis saponins.
Topics: Adenoma; Animals; Carcinogens; Diethylnitrosamine; Lung Neoplasms; Magnoliopsida; Male; Metabolomics | 2015 |
Inhibition of lung cancer in diethylnitrosamine-induced mice by Rhizoma paridis saponins.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Diethylnitrosamine; ErbB | 2017 |
Reduction by dietary matrix metalloproteinase inhibitor BAY 12-9566N of neoplastic development induced by diethylnitrosamine, N-nitrosodimethylamine, or 7,12-dimethylbenz(a)anthracene in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Antineoplastic Agents; Biphenyl Compounds; Carci | 2008 |
Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine.
Topics: Animals; Azacitidine; Cell Line; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dep | 2009 |
Tea polyphenols inhibit cyclooxygenase-2 expression and block activation of nuclear factor-kappa B and Akt in diethylnitrosoamine induced lung tumors in Swiss mice.
Topics: Animals; Anticarcinogenic Agents; Cyclooxygenase 2; Diethylnitrosamine; Dose-Response Relationship, | 2010 |
[Inhibitory effect of thyroxine on late stages of hepatocarcinogenesis induced in suckling mice by diethylnitrosamine].
Topics: Alkylating Agents; Animals; Animals, Suckling; Diethylnitrosamine; Kidney; Liver; Liver Neoplasms, E | 2009 |
Changes of splenic macrophage during the process of liver cancer induced by diethylnitrosamine in rats.
Topics: Animals; Cells, Cultured; Diethylnitrosamine; Disease Models, Animal; Liver Cirrhosis; Liver Neoplas | 2009 |
Epigenetic silencing of cell cycle regulatory genes during 3-methylcholanthrene and diethylnitrosamine-induced multistep rat lung cancer.
Topics: Animals; Carcinoma; Cell Cycle; CpG Islands; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent | 2010 |
[O-aminoazotoluene inhibits DENA-induced hepatocarcinogenesis when used together in mice].
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Diethylnitrosamine; Drug Administration Schedule; Liv | 2010 |
Gas chromatography/time-of-flight mass spectrometry-based metabonomics of hepatocarcinoma in rats with lung metastasis: elucidation of the metabolic characteristics of hepatocarcinoma at formation and metastasis.
Topics: Animals; Biomarkers, Tumor; Carcinoma; Computational Biology; Diethylnitrosamine; Gas Chromatography | 2010 |
CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine.
Topics: Acid Anhydride Hydrolases; Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Prot | 2010 |
Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.
Topics: Animals; Azacitidine; Cadherins; Cell Adhesion; Cell Adhesion Molecules; Cell Transformation, Neopla | 2011 |
Estrogen suppresses metastasis in rat hepatocellular carcinoma through decreasing interleukin-6 and hepatocyte growth factor expression.
Topics: Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Estrogens; Ethinyl Estradiol; Female; Hepato | 2012 |
Suppression of hepatic tumor growth and metastasis by metronomic therapy in a rat model of hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; Cyclophosphamide; Die | 2011 |
Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice.
Topics: Alkylating Agents; Animals; Cell Proliferation; Cytoglobin; Diethylnitrosamine; Dose-Response Relati | 2011 |
Bone marrow-derived cells contribute to NDEA-induced lung squamous cell carcinoma.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carcinoma, Squamous Cell; Cell Differentiat | 2013 |
Chemoprevention of lung carcinogenesis by cacao liquor proanthocyanidins in a male rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Animals; Anthocyanins; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; | 2003 |
[On the different effect in lung carcinoma of diethylnitrosamine in hamsters and rats].
Topics: Animals; Diethylnitrosamine; Liver Neoplasms; Lung Neoplasms; Neoplasms, Experimental; Rats | 1962 |
Induction of malignant tumors in the guinea pig by oral administration of diethylnitrosamine.
Topics: Administration, Oral; Diethylnitrosamine; Guinea Pigs; Liver Neoplasms; Lung Neoplasms; Neoplasms; N | 1963 |
INDUCTION OF MALIGNANT TUMORS IN THE RABBIT BY ORAL ADMINISTRATION OF DIETHYLNITROSAMINE.
Topics: Administration, Oral; Animals; Carcinogens; Diethylnitrosamine; Liver Neoplasms; Lung Neoplasms; Neo | 1965 |
INDUCTION OF MALIGNANT TUMORS IN VARIOUS STRAINS OF MICE BY ORAL ADMINISTRATION OF N-NITROSODIMETHYLAMINE AND N-NITROSODIETHYLAMINE.
Topics: Adenocarcinoma; Adenoma; Administration, Oral; Animals; Carcinogens; Diethylnitrosamine; Dimethylnit | 1965 |
Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma.
Topics: Acetylcysteine; Animals; Aspirin; Blotting, Western; Carcinogens; Diethylnitrosamine; E-Selectin; En | 2004 |
The gap junction protein connexin32 is a mouse lung tumor suppressor.
Topics: Animals; Bromodeoxyuridine; Connexins; Diethylnitrosamine; Disease Models, Animal; Enzyme Activation | 2004 |
Evaluation of mutant frequencies of chemically induced tumors and normal tissues in lambda/cII transgenic mice.
Topics: Animals; Carcinogens; Clone Cells; Diethylnitrosamine; Female; Gene Frequency; Liver; Liver Neoplasm | 2005 |
Increased lung metastasis in transgenic NM23-Null/SV40 mice with hepatocellular carcinoma.
Topics: Animals; Antigens, Neoplasm; Antigens, Viral, Tumor; Biomarkers, Tumor; Blotting, Western; Chi-Squar | 2005 |
Modification of an in vivo lung metastasis model of hepatocellular carcinoma by low dose N-nitrosomorpholine and diethylnitrosamine.
Topics: Alkylating Agents; Animals; Carcinogens; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Mode | 2005 |
Enhancing effects of simultaneous treatment with sodium nitrite on 2-amino-3-methylimidazo[4,5-f]quinoline-induced rat liver, colon and Zymbal's gland carcinogenesis after initiation with diethylnitrosamine and 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Alkylating Agents; Animals; Carcinogens; Cell Transform | 2006 |
Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Antioxidants; Benzo(a)pyrene; Butylate | 2006 |
[Effect of phenobarbital and thyroxine on hepatocarcinogenesis initiated in mice by nitrosoethylurea and diethylnitrosamine].
Topics: Alkylating Agents; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Ethylnitrosourea; F | 2005 |
Anticarcinogenic effects of hexaamminecobalt(III) chloride in mice initiated with diethylnitrosamine.
Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Catalase; Cobalt; Diethylnitrosamine; gamma-Glu | 2007 |
Pulmonary neuroepithelial bodies, neuroendocrine cells, and pulmonary tumors.
Topics: Animals; APUD Cells; Cricetinae; Diethylnitrosamine; Epithelial Cells; Humans; Lung Neoplasms; Neuro | 1982 |
Induction of lung carcinoma by intralobar bronchial instillation of iodized oil in rats.
Topics: Animals; Carcinoma, Squamous Cell; Diethylnitrosamine; Female; Iodized Oil; Lung Neoplasms; Male; Me | 1984 |
Inhibition by phenobarbital and lack of effect of amobarbital on the development of liver tumors induced by N-nitrosodiethylamine in juvenile B6C3F1 mice.
Topics: Adenocarcinoma; Adenoma; Amobarbital; Animals; Body Weight; Diethylnitrosamine; Liver Neoplasms, Exp | 1984 |
Carcinogenicity of diethylnitrosamine in newborn, infant, and adult mice.
Topics: Age Factors; Animals; Diethylnitrosamine; Female; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, | 1984 |
Effects of sequential exposure to aflatoxin B1 and diethylnitrosamine on vascular and stomach tissue and additional target organs in rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Diethylnitrosamine; H | 1980 |
Species specificity in nitrosamine carcinogenesis.
Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Liver Neoplasms; Lung Neopla | 1983 |
Temporal advancement of diethylnitrosamine carcinogenesis in aging mice.
Topics: Aging; Animals; Diethylnitrosamine; Female; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms, Experi | 1981 |
Ureido-ethyl-imidazolines active against autochtonous diethylnitrosamine-induced epidermoid, papillary and adenocarcinomatous tumors of the respiratory tract of Syrian hamsters and against human bronchogenic carcinomas in nu/nu mice.
Topics: Animals; Antineoplastic Agents; Carcinoma, Bronchogenic; Cricetinae; Diethylnitrosamine; Drug Evalua | 1981 |
A light and electron microscopic study of liver and lung tumors induced by a single low dose of diethylnitrosamine (DEN) in C57BLXC3H F1 mice.
Topics: Animals; Diethylnitrosamine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Mice; Mice, Inbred C3H; M | 1981 |
Tumorigenicity of N-nitroso-diaethyl, -dimethyl and -diphenyl-amines in skin painting experiments. A study utilizing the tetrazolium test and skin applications on hairless mice.
Topics: Adenoma; Animals; Diethylnitrosamine; Dimethylnitrosamine; Female; Lung Neoplasms; Male; Mice; Neopl | 1980 |
[Observations on cancer of the lung and fore-stomach in mice induced by diethylnitrosamine (gastric intubation) (author's transl)].
Topics: Animals; Carcinoma, Squamous Cell; Diethylnitrosamine; Lung Neoplasms; Mice; Nitrosamines; Stomach N | 1980 |
Cytokeratin patterns of liver carcinomas induced by diethylnitrosamine in monkeys.
Topics: Animals; Antibodies, Monoclonal; Carcinoma, Hepatocellular; Chlorocebus aethiops; Diethylnitrosamine | 1995 |
Promotion of N-nitrosodiethylamine-initiated hepatocellular tumors and hepatoblastomas by 2,3,7,8-tetrachlorodibenzo-p-dioxin or Aroclor 1254 in C57BL/6, DBA/2, and B6D2F1 mice.
Topics: Animals; Aroclors; Blotting, Western; Carcinogens; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 C | 1995 |
Modulating effects of ellagic acid, vanillin and quercetin in a rat medium term multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Animals; Benzaldehydes; Butylhydroxybutylnitrosamine; Diethylnitrosamine; Dim | 1995 |
Flow cytometric DNA-ploidy and proliferative activity of diethylnitrosamine-induced hepatocellular carcinoma and pulmonary metastases in monkeys.
Topics: Animals; Cell Division; Chlorocebus aethiops; Diethylnitrosamine; DNA, Neoplasm; Flow Cytometry; Liv | 1995 |
[Study on initiation of human lung carcinogenesis].
Topics: Anticarcinogenic Agents; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosamine; Human | 1993 |
Failure of ozone and nitrogen dioxide to enhance lung tumor development in hamsters.
Topics: Animals; Cricetinae; Diethylnitrosamine; Liver Neoplasms; Lung Neoplasms; Mesocricetus; Nitrogen Dio | 1993 |
Protective effects of green tea polyphenols administered by oral intubation against chemical carcinogen-induced forestomach and pulmonary neoplasia in A/J mice.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Diethylnitrosamine; Female; | 1993 |
Tumor promotion by an anticonvulsant agent, phenytoin, in mouse liver: correlation with CYP2B induction.
Topics: Adenoma; Animals; Body Weight; Carcinogens; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; | 1993 |
Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors.
Topics: Animals; Base Sequence; Diethylnitrosamine; DNA, Neoplasm; DNA, Single-Stranded; Dose-Response Relat | 1993 |
Further evidence of the tumor-suppressive effects of cadmium in the B6C3F1 mouse liver and lung: late stage vulnerability of tumors to cadmium and the role of metallothionein.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Cadmium; Diethylnitrosamine; Liver; Liver Neoplasms, | 1993 |
Enhancement of tumorigenesis by N-nitrosodiethylamine, N-nitrosopyrrolidine and N6-(methylnitroso)-adenosine by ethanol.
Topics: Animals; Carcinogens; Diethylnitrosamine; Drug Interactions; Ethanol; Female; Lung Neoplasms; Male; | 1993 |
Modulation of N-nitrosodiethylamine-induced hamster lung tumors by ozone.
Topics: Administration, Inhalation; Animals; Body Weight; Cocarcinogenesis; Cricetinae; Diethylnitrosamine; | 1993 |
Protection against N-nitrosodiethylamine and benzo[a]pyrene-induced forestomach and lung tumorigenesis in A/J mice by green tea.
Topics: Animals; Benzo(a)pyrene; Diethylnitrosamine; Female; Intestinal Neoplasms; Lung Neoplasms; Mice; Mic | 1993 |
Quantitative evaluation of lysozyme- and CD68-positive Kupffer cells in diethylnitrosamine-induced hepatocellular carcinomas in monkeys.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Carcinogens; Diethylnitrosamine; I | 1995 |
Chemopreventive effects of green and black tea on pulmonary and hepatic carcinogenesis.
Topics: Adenoma; Administration, Oral; Analysis of Variance; Animals; Carcinogens; Diethylnitrosamine; Disea | 1996 |
Induction of lung carcinogenesis in AKR-mice by N-nitrosodiethylamine/phenobarbitone, associated with high expression of c-myc and c-jun oncoproteins.
Topics: Animals; Carcinogens; Diethylnitrosamine; Lung Neoplasms; Male; Mice; Mice, Inbred AKR; Neoplasm Pro | 1997 |
Effects of n-tritriacontane-16,18-dione, curcumin, chlorphyllin, dihydroguaiaretic acid, tannic acid and phytic acid on the initiation stage in a rat multi-organ carcinogenesis model.
Topics: Aminobiphenyl Compounds; Animals; Antimutagenic Agents; Antineoplastic Agents; Antioxidants; Carcino | 1997 |
Changes in protein kinase C alpha, delta and in nuclear beta isoform expression in tumour and lung metastatic nodules induced by diethylnitrosamine in the rat.
Topics: Animals; Cadherins; Carcinogens; Cell Nucleus; Diethylnitrosamine; Isoenzymes; Liver Neoplasms, Expe | 1997 |
Differential screening of a human chromosome 3 library identifies hepatocyte growth factor-like/macrophage-stimulating protein and its receptor in injured lung. Possible implications for neuroendocrine cell survival.
Topics: Animals; Apoptosis; Blotting, Southern; Chromosomes, Human, Pair 3; Cricetinae; Diethylnitrosamine; | 1997 |
Studies on the proliferative activity of diethylnitrosamine-induced hepatocellular carcinomas in monkeys.
Topics: Adenoma; Animals; Carcinogens; Cell Division; Chlorocebus aethiops; Diagnosis, Differential; Diethyl | 1997 |
Chemoprevention by lycopene of mouse lung neoplasia after combined initiation treatment with DEN, MNU and DMH.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carotenoids; Chemoprevention; Colonic Neoplasms; Diethy | 1997 |
Inhibition of hepatocellular carcinoma by glycyrrhizin in diethylnitrosamine-treated mice.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Diethylnitrosamine; Disease Models, Animal; | 1999 |
Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice.
Topics: Animals; Anticarcinogenic Agents; Chemoprevention; Diethylnitrosamine; Ellagic Acid; Glutathione; Li | 1999 |
Effect of fasting/refeeding on the incidence of chemically induced hepatocellular carcinoma in the rat.
Topics: Animals; Carcinogens; Diethylnitrosamine; Food; Incidence; Liver Neoplasms, Experimental; Lung Neopl | 1999 |
Establishment of an in vivo highly metastatic rat hepatocellular carcinoma model.
Topics: Animals; Cadherins; Carcinogens; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Models, Anim | 1999 |
Chemoprevention of lung cancer by lycopene.
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Anticarcinogenic Agents; Carcinogens; Caroteno | 2000 |
Anticarcinogenic effect of black tea on pulmonary tumors in Swiss albino mice.
Topics: Adenocarcinoma; Alkylating Agents; Animals; Anticarcinogenic Agents; Carcinogens; Diethylnitrosamine | 2002 |
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats].
Topics: Alkylating Agents; Animals; Carcinoma, Squamous Cell; Diethylnitrosamine; Female; Gene Expression Re | 2002 |
Effect of a single treatment with the alkylating carcinogens dimethynitrosamine, diethylnitrosamine and methyl methanesulphonate, on liver regenerating after partial hepatectomy. I. Test for induction of liver carcinomas.
Topics: Adenocarcinoma; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Dimethylnitrosamine; Female; | 1975 |
[Studies on the influence of anticoagulants on metastase formation of autochthonic hepatomas in the rat (author's transl)].
Topics: Animals; Anticoagulants; Aspirin; Carcinoma, Hepatocellular; Coumarins; Diethylnitrosamine; Female; | 1975 |
[Transplacental carcinogenic action of diethylnitrosamine in the Dzungarian hamster (author's transl)].
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Cricetinae; Cystadenoma; Diethylnitrosamine; | 1977 |
Tumor frequency and characteristics after a single dose of dimethylnitrosamine or diethylnitrosamine in partially hepatectomized rats.
Topics: Adenocarcinoma; Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Dimethyl | 1977 |
Morphology and metastatic nature of induced hepatic nodular lesions in C57BL x C3H F1 mice.
Topics: Animals; Benzidines; Benzopyrenes; Carcinoma, Hepatocellular; Diethylnitrosamine; Ethylnitrosourea; | 1978 |
Suppression of chemical (DEN) carcinogenesis in SWR/J mice by goat antibodies against endogenous murine leukemia viruses.
Topics: Animals; Antibodies, Viral; Diethylnitrosamine; Female; Goats; Immunization, Passive; Immunoglobulin | 1978 |
Selective sex-related modification of diethylnitrosamine-induced carcinogenesis in BALB/c mice by concomitant administration of butylated hydroxytoluene.
Topics: Animals; Butylated Hydroxytoluene; Carcinoma, Squamous Cell; Cresols; Diethylnitrosamine; Enzyme Ind | 1978 |
Carcinogenesis in tissue culture 30: malignant transformation of normal rat liver cells treated with diethylnitrosamine in tissue culture with special reference to the differential effects of cytochalasin B on various cells with and without tumorigenicity
Topics: Animals; Animals, Suckling; Cell Nucleus; Cell Transformation, Neoplastic; Culture Techniques; Cytoc | 1979 |
Inhalation studies with Syrian golden hamsters.
Topics: Aerosols; Animals; Asbestos; Atmosphere Exposure Chambers; Cobalt; Cricetinae; Diethylnitrosamine; L | 1979 |
Carcinogenicity of N-nitrosodiethylamine in hibernating and nonhibernating European hamsters.
Topics: Adenocarcinoma; Animals; Basement Membrane; Carcinoma, Squamous Cell; Cricetinae; Diethylnitrosamine | 1977 |
Morphology of diethylnitrosamine-induced lung tumours in Dzungarian dwarf hamsters.
Topics: Adenocarcinoma; Adenoma; Animals; Cricetinae; Diethylnitrosamine; Lung Neoplasms; Neoplasms, Experim | 1977 |
Multi-hit kinetics of tumor formation, with special reference to experimental liver and human lung carcinogenesis and some gneral conclusions.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Dose-Response Relationshi | 1977 |
Ultrastructural alterations of APUD cells during nitrosamine-induced lung carcinogenesis.
Topics: Animals; Cell Division; Cricetinae; Diethylnitrosamine; Lung Neoplasms; Male; Microscopy, Electron; | 1977 |
[Experimental carcinogenesis in the respiratory tract using the European field hamster (Cricetus cricetus L.) as a model].
Topics: Adenocarcinoma; Animals; Azocines; Carcinoma, Squamous Cell; Cricetinae; Diethylnitrosamine; Lung Ne | 1977 |
Transplacental carcinogenic effects of diethylnitrosamine in mice.
Topics: Animals; Carcinogens; Diethylnitrosamine; Female; Gestational Age; Leukemia; Lung Neoplasms; Male; M | 1976 |
Methodoloigcal study on examiniation of primary tumors of the respiratory tract "in toto" and histologically.
Topics: Animals; Cricetinae; Diethylnitrosamine; Female; Laryngeal Neoplasms; Lung Neoplasms; Methods; Respi | 1976 |
Ultrastructural alterations of nonciliated cells after nitrosamine treatment and their significance for pulmonary carcinogenesis.
Topics: Animals; Bronchi; Cricetinae; Diethylnitrosamine; Epithelial Cells; Epithelium; Lung Neoplasms; Male | 1976 |
Carcinogenic effects of a single dose of diethylnitrosamine in three unrelated strains of mice: genetic dependence of the induced tumor types and incidence.
Topics: Animals; Carcinogens; Diethylnitrosamine; Female; Genotype; Leukemia, Experimental; Liver Neoplasms; | 1976 |
Proliferation of endocrine (APUD-type) cells during early N-diethylnitrosamine-induced lung carcinogenesis in hamsters.
Topics: Animals; Cell Division; Cricetinae; Diethylnitrosamine; Epithelial Cells; Epithelium; Lung Neoplasms | 1976 |
Carcinogenic and cocarcinogenic effects of inhaled synthetic smog and ferric oxide particles.
Topics: Air Pollutants; Animals; Body Weight; Carcinogens; Cricetinae; Diethylnitrosamine; Drug Synergism; F | 1975 |
Comparative study of the ultrastructure of Tracheal and pulmonary tumours induced by multiple intratracheal instillations of diethylnitrosamine in Syrian golden hamsters.
Topics: Adenoma; Animals; Cell Membrane; Cell Nucleus; Cilia; Cricetinae; Diethylnitrosamine; Epithelial Cel | 1975 |
Carcinogenic effects of different nitroso-compounds in Chinese hamsters. I. Dimethylnitrosamine and N-diethylnitrosamine.
Topics: Animals; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Esop | 1976 |
Induction and spontaneous regression of intense pulmonary neuroendocrine cell differentiation in a model of preneoplastic lung injury.
Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Cricetinae; Diethylnitrosamine; Dise | 1992 |
Animal models for chemoprevention of respiratory cancer.
Topics: Animals; Biotransformation; Carcinoma, Squamous Cell; Cricetinae; Diethylnitrosamine; Disease Models | 1992 |
Mutagenesis of the K-ras protooncogene in mouse lung tumors induced by N-ethyl-N-nitrosourea or N-nitrosodiethylamine.
Topics: Animals; Diethylnitrosamine; Ethylnitrosourea; Female; Genes, ras; Lung Neoplasms; Male; Mice; Mutag | 1992 |
Lung adenoma development and NK activity in mice treated with multiple carcinogens.
Topics: Adenoma; Animals; Diethylnitrosamine; Female; Killer Cells, Natural; Lung Neoplasms; Methylnitrosour | 1992 |
Protection against benzo[a]pyrene- and N-nitrosodiethylamine-induced lung and forestomach tumorigenesis in A/J mice by water extracts of green tea and licorice.
Topics: Animals; Benzo(a)pyrene; Diethylnitrosamine; Female; Glycyrrhiza; Lung Neoplasms; Mice; Mice, Inbred | 1992 |
Activation of the Ki-ras gene in spontaneous and chemically induced lung tumors in CD-1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diethylnitrosamine; DNA Mutational Analysis; Gene Express | 1992 |
Effect of combined deficiency of fat and vitamin A on N-nitrosodiethylamine-induced lung carcinogenesis in mice.
Topics: Animals; Dietary Fats; Diethylnitrosamine; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Vitamin | 1992 |
Induction and spontaneous regression of pulmonary neuroendocrine cell hyperplasia in a hamster model.
Topics: Animals; Calcitonin; Calcitonin Gene-Related Peptide; Cell Division; Cricetinae; Diethylnitrosamine; | 1992 |
Inhibition of N-nitrosodiethylamine- and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorigenesis in A/J mice by green tea and black tea.
Topics: Animals; Carcinogens; Diethylnitrosamine; Female; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines | 1992 |
Increased c-Ki-ras expression in hamster lung exposed to N-nitrosodiethylamine and hyperoxia as detected by the polymerase chain reaction.
Topics: Animals; Base Sequence; Cricetinae; Diethylnitrosamine; Endocrine System Diseases; Eosine Yellowish- | 1991 |
Strain A/J mouse lung adenoma growth patterns vary when induced by different carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenoma; Aflatoxins; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformatio | 1991 |
Different modifying responses of capsaicin in a wide-spectrum initiation model of F344 rat.
Topics: Animals; Capsaicin; Cocarcinogenesis; Diethylnitrosamine; Liver Neoplasms, Experimental; Lung Neopla | 1991 |
Anticarcinogenic effects of cadmium in B6C3F1 mouse liver and lung.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Barbital; Cadmium; Cadmium Chloride; Diethylni | 1991 |
Promoting effect of sodium chloride solution mist on the induction of papillomas on Syrian hamster tracheal mucosa following administration of diethylnitrosamine.
Topics: Adenocarcinoma; Administration, Inhalation; Animals; Cricetinae; Diethylnitrosamine; Hyperplasia; Lu | 1991 |
Rat hepatocarcinogenesis induced by N-nitrosodiethylamine and N-nitrosomorpholine continuously administered at low doses. From basophilic areas of hepatocytes to hepatocellular tumors.
Topics: Adenoma; Administration, Oral; Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, | 1991 |
Successful chemotherapy of experimental neuroendocrine lung tumors in hamsters with an antagonist of Ca2+/calmodulin.
Topics: Animals; Cricetinae; Diethylnitrosamine; Dihydropyridines; Laryngeal Neoplasms; Lung Neoplasms; Male | 1990 |
Pulmonary bombesin and calcitonin in hamsters during exposure to hyperoxia and diethylnitrosamine.
Topics: Animals; Body Weight; Bombesin; Calcitonin; Chromatography, High Pressure Liquid; Cricetinae; Cytopl | 1990 |
Crystalline inclusions associated with lung adenomas in C57BLxC3H F1 mice.
Topics: Adenoma; alpha 1-Antitrypsin; Animals; Crosses, Genetic; Diethylnitrosamine; Immunoglobulin A; Immun | 1988 |
Immunohistochemical demonstration of Clara cell antigen in lung tumors of bronchiolar origin induced by N-nitrosodiethylamine in Syrian golden hamsters.
Topics: Animals; Antigens; Bronchi; Cricetinae; Diethylnitrosamine; Epitopes; Female; Hyperplasia; Immunohis | 1989 |
Tumours of the respiratory tract in rats and hamsters following chronic inhalation of engine exhaust emissions.
Topics: Animals; Cricetinae; Diethylnitrosamine; Female; Gasoline; Lung Neoplasms; Male; Mesocricetus; Petro | 1989 |
Promotion of malignant 'embryonal' liver tumors by phenobarbital: increased incidence and shortened latency of hepatoblastomas in (DBA/2 x C57BL/6)F1 mice initiated with N-nitrosodiethylamine.
Topics: alpha-Fetoproteins; Animals; Biomarkers, Tumor; Crosses, Genetic; Diethylnitrosamine; Female; Hemang | 1989 |
Cell type specific, receptor-mediated modulation of growth kinetics in human lung cancer cell lines by nicotine and tobacco-related nitrosamines.
Topics: Adenocarcinoma; Carcinogens; Cell Division; Diethylnitrosamine; Hexamethonium; Hexamethonium Compoun | 1989 |
Diethylnitrosamine-induced pulmonary endocrine cell hyperplasia and its association with adenomatosis and adenocarcinoma in rabbits.
Topics: Adenocarcinoma; Adenoma; Animals; Diethylnitrosamine; Endocrine Glands; Hyperplasia; Lung; Lung Neop | 1989 |
Focal impairment of growth in hepatocellular neoplasms of C57BL/6 mice: a possible explanation for the strain's resistance to hepatocarcinogenesis.
Topics: Animals; Diethylnitrosamine; DNA Replication; Immunity, Innate; Liver Neoplasms, Experimental; Lung | 1989 |
Comparative tumorigenicity of N-nitroso-2-hydroxymorpholine, N-nitrosodiethanolamine and N-nitrosomorpholine in A/J mice and F344 rats.
Topics: Adenocarcinoma; Animals; Carcinogens; Diethylnitrosamine; Female; Hemangiosarcoma; Liver Neoplasms; | 1989 |
Inhibition of N-diethylnitrosamine metabolism by human lung cancer cell lines with features of well differentiated pulmonary endocrine cells.
Topics: Carbon Dioxide; Carcinoid Tumor; Carcinoma, Small Cell; Cell Differentiation; Diethylnitrosamine; Hu | 1987 |
Cell type-specific differences in metabolic activation of N-nitrosodiethylamine by human lung cancer cell lines.
Topics: Adenocarcinoma; Biotransformation; Carcinoid Tumor; Carcinoma, Small Cell; Cell Line; Diethylnitrosa | 1987 |
[Studies of pulmonary carcinoma-inducing effect of Yunnan Tin Mine smeltery furnace chimney dust and the synergistic effect of this dust plus diethylnitrosamine (DEN) on hamsters].
Topics: Adenocarcinoma; Animals; Cricetinae; Diethylnitrosamine; Drug Synergism; Dust; Female; Lung Neoplasm | 1985 |
[Induction of lung tumors in mice by low doses of ionizing radiation and diethylnitrosamine].
Topics: Animals; Cocarcinogenesis; Cystadenocarcinoma; Diethylnitrosamine; Gamma Rays; Lung Neoplasms; Male; | 1987 |
Preferential metabolism of N-nitrosodiethylamine by two cell lines derived from human pulmonary adenocarcinomas.
Topics: Adenocarcinoma; Carbon Dioxide; Carbon Radioisotopes; Cell Line; Diethylnitrosamine; Humans; Kinetic | 1986 |
4-Nitroquinoline 1-oxide-induced pulmonary endocrine cell hyperplasia in Syrian golden hamster.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cricetinae; Diethylnitrosamine; Hyperplasia; Lung; Lung Neoplasms | 1986 |
Modifying effects of butylated hydroxyanisole, di(2-ethylhexyl)phthalate or indomethacin on mouse hepatocarcinogenesis initiated by N-nitrosodiethylamine.
Topics: Adenoma; Animals; Butylated Hydroxyanisole; Cocarcinogenesis; Diethylhexyl Phthalate; Diethylnitrosa | 1986 |
Dose-response relationship of diethylnitrosamine-initiated tumors in neonatal balb/c mice: effect of phenobarbital promotion.
Topics: Adenoma; Animals; Animals, Newborn; Cocarcinogenesis; Diethylnitrosamine; Dose-Response Relationship | 1988 |
A comparison of the carcinogenicity of N-nitrosodiethylamine and N-nitrosodimethylamine after intratracheal instillation into Syrian golden hamsters.
Topics: Animals; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; Liver Neoplasms, Experimental; Lung Ne | 1988 |
An animal model for neuroendocrine lung cancer.
Topics: Animals; Cricetinae; Diethylnitrosamine; Disease Models, Animal; Histocytochemistry; Hyperplasia; Lu | 1988 |
Malignant transformation of human fetal lung fibroblasts induced by nitrosamine compounds in vitro.
Topics: Cell Transformation, Neoplastic; Diethylnitrosamine; Fetus; Fibroblasts; Humans; Karyotyping; Lung N | 1986 |
[Pulmonary tumors induced by diethylnitrosamine in mice].
Topics: Adenoma; Animals; Diethylnitrosamine; Lung Neoplasms; Male; Mice | 1987 |
Inhibitory effects of benzyl isothiocyanate administered shortly before diethylnitrosamine or benzo[a]pyrene on pulmonary and forestomach neoplasia in A/J mice.
Topics: Animals; Benzo(a)pyrene; Diethylnitrosamine; Drug Interactions; Isothiocyanates; Lung Neoplasms; Mic | 1987 |
Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats.
Topics: Adenocarcinoma; Animals; Choline; Cocarcinogenesis; DDT; Diethylnitrosamine; Liver Neoplasms; Lung N | 1986 |
Inhibitory effects of 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (Oltipraz) on carcinogenesis induced by benzo[a]pyrene, diethylnitrosamine and uracil mustard.
Topics: Animals; Benzo(a)pyrene; Diethylnitrosamine; Female; Lung Neoplasms; Mice; Mice, Inbred ICR; Neoplas | 1986 |
Organ specific modifying potential of ethinyl estradiol on carcinogenesis initiated with different carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Interactio | 1987 |
Immunocytochemical localization of the surfactant apoprotein and Clara cell antigen in chemically induced and naturally occurring pulmonary neoplasms of mice.
Topics: Adenoma; Animals; Antigens; Apoproteins; Carcinoma; Diethylnitrosamine; Female; Hyperplasia; Immunoe | 1985 |
Comparative study on the carcinogenicity of N-nitrosodiethylamine and benzo[a]pyrene to the lung of Syrian golden hamsters induced by intermittent instillations to the trachea.
Topics: Adenoma; Administration, Topical; Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cricetinae; Die | 1985 |
Kinetics of formation and persistence of ethylguanines in DNA of rats and hamsters treated with diethylnitrosamine.
Topics: Alkylation; Animals; Cricetinae; Diethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; | 1985 |
Effects of wood dust exposure and diethylnitrosamine in an animal experimental system.
Topics: Adenocarcinoma; Animals; Cricetinae; Diethylnitrosamine; Dust; Environmental Exposure; Laryngeal Neo | 1985 |