diethylnitrosamine has been researched along with Cancer of Kidney in 84 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was designed to evaluate the protective effects of hesperidin, a flavonoid on DEN initiated and Fe-NTA promoted renal carcinogenesis in Wistar rats." | 3.88 | Anti-carcinogenic effect of hesperidin against renal cell carcinoma by targeting COX-2/PGE2 pathway in Wistar rats. ( Saidullah, B; Siddiqi, A; Sultana, S, 2018) |
| "The prevalence of Ki-ras, Ha-ras and N-ras point mutation within exons 1 and 2 was studied in 17 cases of renal cell tumors (8 carcinomas and 9 adenomas) induced by N-ethyl-N-hydroxyethyl-nitrosamine or N-nitrosomorpholine." | 3.68 | Absence of ras family point mutations at codons 12, 13 and 61 in N-ethyl-N-hydroxyethylnitrosamine- or N-nitrosomorpholine-induced renal cell tumors in rats. ( Hirono, I; Ito, M; Iwase, T; Matsumoto, K; Nagao, M; Nishida, Y; Oyama, F; Titani, K; Tsuda, H; Ushijima, T, 1992) |
| " injection of diethylnitrosamine (DEN) (25-mg/kg body weight)." | 3.67 | Promoting effect of nicotinamide on the development of renal tubular cell tumors in rats initiated with diethylnitrosamine. ( Jirtle, RL; Michalopoulos, G; Novicki, DL; Novotny, A; Rosenberg, MR, 1985) |
| "2% N-ethyl-N-hydroxyethylnitrosamine (EHEN) for 2 weeks induced hepatocellular carcinoma in 3 and renal tubular cell tumors in 7 of 9 Wistar rats." | 3.66 | Histopathological studies on renal tubular cell tumors in rats treated with N-ethyl-N-hydroxyethylnitrosamine. ( Hiasa, Y; Iwata, C; Ohshima, M; Tanikake, T, 1979) |
| "Renal cancer was initiated by single intraperitoneal (i." | 1.39 | Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-κB. ( Ali, F; Khan, AQ; Khan, R; Lateef, A; Qamar, W; Rehman, MU; Sultana, S; Tahir, M, 2013) |
| "Potassium bromate (KBrO(3)) is a genotoxic carcinogen inducing kidney cancers at high doses in male F344 rats, but little is known about its carcinogenic effects in other strains of rats." | 1.35 | Potassium bromate enhances N-ethyl-N-hydroxyethylnitrosamine-induced kidney carcinogenesis only at high doses in Wistar rats: indication of the existence of an enhancement threshold. ( Doi, K; Fukushima, S; Hamoud, AS; Kakehashi, A; Kitano, M; Kushida, M; Morimura, K; Wanibuchi, H; Wei, M; Yamaguchi, T, 2009) |
| " The better correlation between 8-oxodG formation and tumor response indicates that dose-response information from the female rat would be much more relevant to human risk assessment." | 1.33 | Etiology of bromate-induced cancer and possible modes of action-studies in Japan. ( Kurokawa, Y; Umemura, T, 2006) |
| "Ferric nitrilotriacetate (Fe-NTA) is a known complete renal carcinogen." | 1.30 | Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rat: implications for the involvement of oxidative stress. ( Athar, M; Iqbal, M, 1998) |
| " Our data show that NDGA can abrogate the toxic and tumour-promoting effects of Fe-NTA in liver and kidney of mice and can serve as a potent chemopreventive agent to suppress oxidant-induced tissue injury and tumorigenesis." | 1.30 | Nordihydroguairetic acid is a potent inhibitor of ferric-nitrilotriacetate-mediated hepatic and renal toxicity, and renal tumour promotion, in mice. ( Ansar, S; Athar, M; Iqbal, M, 1999) |
| "The F2 rats which carried renal cell carcinoma were shown to possess the incidence of homozygosity of the LEC allele which is higher than that of the other genotypes at SSLP markers on chromosome 5 (chi2 = 17." | 1.30 | Identification of a locus for susceptibility to renal cell carcinoma in the Long-Evans Cinnamon rat. ( Hino, A; Izumi, K; Matsumoto, K; Sasaki, Y; Wei, K; Wei, S; Yamada, T, 1999) |
| " At dosage levels equimolar to 500 ppm PB, none of the three compounds promoted development of hepatocellular adenomas or carcinomas, in contrast to PB." | 1.28 | Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid on N-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat. ( Diwan, BA; Henneman, JR; Lubet, RA; Nims, RW; Rice, JM; Ward, JM, 1992) |
| "d-Limonene treatment alone caused a significant increase in the number of atypical tubules and atypical hyperplasias in F344 rats when compared with the F344 vehicle control." | 1.28 | The presence of alpha 2u-globulin is necessary for d-limonene promotion of male rat kidney tumors. ( Dietrich, DR; Swenberg, JA, 1991) |
| "After the gavage of 200 mg N-nitrosodiethylamine per kg body weight only kidney tumors developed while long-term administration of 10 ppm N-nitrosodiethylamine induced esophageal tumors and hepatocellular carcinomas in female rats (SIV 50)." | 1.26 | [Comparative investigations on the organotropic carcinogenic effect of different N-nitroso compounds with rat after single and chronic treatment (author's transl)]. ( Kouros, M; Manncke, K; Schweinsberg, F, 1979) |
| "In mice given a single dose of diethylnitrosamine, a hepatonecrotic dose of carbon tetrachloride, 5 weeks after dosing with DEN and repeated 6 times at 4-weekly intervals, augmented the tumour yield in the livers." | 1.26 | Influence of repeated liver regeneration on hepatic carcinogenesis by diethylnitrosamine in mice. ( McGuire, LJ; Poound, AW, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (46.43) | 18.7374 |
| 1990's | 25 (29.76) | 18.2507 |
| 2000's | 10 (11.90) | 29.6817 |
| 2010's | 7 (8.33) | 24.3611 |
| 2020's | 3 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, F | 1 |
| Shi, X | 1 |
| Yang, W | 1 |
| Gao, C | 1 |
| Cui, Z | 1 |
| Wang, W | 1 |
| Singh, D | 1 |
| Yadav, E | 1 |
| Kumar, V | 2 |
| Verma, A | 2 |
| Iqbal, M | 4 |
| Shah, MD | 1 |
| Vun-Sang, S | 1 |
| Okazaki, Y | 1 |
| Okada, S | 1 |
| Siddiqi, A | 1 |
| Saidullah, B | 1 |
| Sultana, S | 3 |
| Sharma, V | 2 |
| Matsushita, K | 1 |
| Ishii, Y | 1 |
| Takasu, S | 1 |
| Kuroda, K | 1 |
| Kijima, A | 1 |
| Tsuchiya, T | 1 |
| Kawaguchi, H | 1 |
| Miyoshi, N | 1 |
| Nohmi, T | 1 |
| Ogawa, K | 1 |
| Nishikawa, A | 2 |
| Umemura, T | 2 |
| Ahmed, B | 1 |
| Anwar, F | 1 |
| Rahman, M | 1 |
| Patel, DK | 1 |
| Kaithwas, G | 1 |
| Rani, R | 1 |
| Bhatt, PC | 1 |
| Wei, M | 1 |
| Hamoud, AS | 1 |
| Yamaguchi, T | 1 |
| Kakehashi, A | 1 |
| Morimura, K | 1 |
| Doi, K | 1 |
| Kushida, M | 1 |
| Kitano, M | 1 |
| Wanibuchi, H | 1 |
| Fukushima, S | 6 |
| Pracheta, P | 1 |
| Singh, L | 1 |
| Paliwal, R | 1 |
| Sharma, S | 2 |
| Yadav, S | 1 |
| Vargas-Olvera, CY | 1 |
| Sánchez-González, DJ | 1 |
| Solano, JD | 1 |
| Aguilar-Alonso, FA | 1 |
| Montalvo-Muñoz, F | 1 |
| Martínez-Martínez, CM | 1 |
| Medina-Campos, ON | 1 |
| Ibarra-Rubio, ME | 1 |
| Rehman, MU | 1 |
| Tahir, M | 1 |
| Khan, AQ | 1 |
| Khan, R | 1 |
| Lateef, A | 1 |
| Qamar, W | 1 |
| Ali, F | 1 |
| Satake, N | 2 |
| Miyagawa, M | 1 |
| Sakurai, J | 1 |
| Mitani, H | 1 |
| Kobayashi, T | 1 |
| Tamura, H | 1 |
| Hino, O | 3 |
| TAKAYAMA, S | 1 |
| OOTA, K | 1 |
| Khan, N | 1 |
| Kurokawa, Y | 4 |
| Hiasa, Y | 12 |
| Lin, JC | 1 |
| Konishi, N | 9 |
| Kitahori, Y | 9 |
| Enoki, N | 3 |
| Shimoyama, T | 4 |
| Tsuda, H | 13 |
| Sakata, T | 7 |
| Masui, T | 2 |
| Imaida, K | 2 |
| Ito, N | 14 |
| Ohshima, M | 6 |
| Fujita, T | 2 |
| Yuasa, T | 2 |
| Miyashiro, A | 2 |
| Shirai, T | 6 |
| Masuda, A | 1 |
| Tamano, S | 2 |
| Takahashi, M | 1 |
| Kokubo, T | 1 |
| Ohno, Y | 1 |
| Hayashi, Y | 3 |
| Shirachi, DY | 1 |
| Johansen, MG | 1 |
| McGowan, JP | 1 |
| Tu, SH | 1 |
| Hirose, M | 8 |
| Ogiso, T | 3 |
| Schmähl, D | 2 |
| Scherf, HR | 1 |
| Okumura, M | 1 |
| Hagiwara, A | 2 |
| Hasegawa, R | 3 |
| Dragan, VP | 1 |
| Vaughan, J | 1 |
| Jordan, VC | 1 |
| Pitot, HC | 1 |
| Akagi, K | 2 |
| Hoshiya, T | 2 |
| Mizoguchi, Y | 1 |
| Nishii, K | 2 |
| Hayashi, I | 1 |
| Nakaoka, S | 3 |
| Matsumoto, K | 5 |
| Yabuno, T | 1 |
| Okazaki, S | 1 |
| Takahashi, S | 3 |
| Futakuchi, M | 1 |
| Saito, K | 1 |
| Takashi, M | 3 |
| Nakano, Y | 3 |
| Takagi, Y | 2 |
| Yamada, Y | 3 |
| Hibi, H | 2 |
| Miyake, K | 3 |
| Kato, K | 1 |
| Blanck, A | 1 |
| Assefaw-Redda, Y | 1 |
| Eriksson, LC | 1 |
| Gustafsson, JA | 1 |
| Ekvärn, S | 1 |
| Hällström, IP | 1 |
| Iwase, T | 2 |
| Nishida, Y | 2 |
| Baba, H | 1 |
| Kimura, J | 1 |
| Yoshida, Y | 1 |
| Kurata, M | 1 |
| Urakami, S | 2 |
| Tokuzen, R | 2 |
| Igawa, M | 1 |
| Athar, M | 3 |
| Hirayama, Y | 1 |
| Izumi, K | 4 |
| Giri, U | 1 |
| Yoshioka, N | 1 |
| Cho, M | 1 |
| Hirao, K | 2 |
| Kuwashima, S | 2 |
| Ansar, S | 1 |
| Wei, K | 1 |
| Hino, A | 1 |
| Wei, S | 1 |
| Sasaki, Y | 1 |
| Yamada, T | 2 |
| Furukawa, F | 1 |
| Miyauchi, M | 1 |
| Nakamura, H | 1 |
| Son, HY | 1 |
| Yamagishi, M | 1 |
| Fujioka, T | 1 |
| Suzuki, Y | 2 |
| Okamoto, T | 1 |
| Mastushita, N | 1 |
| Hasegawa, M | 1 |
| Omori, S | 1 |
| Iwahori, Y | 1 |
| Asamoto, M | 3 |
| Iigo, M | 1 |
| Hasegawa, F | 1 |
| Satoh, T | 1 |
| Ishidate, M | 1 |
| Takashima, K | 1 |
| Ozono, S | 1 |
| Nakanou, I | 1 |
| Ota, M | 1 |
| Tanaka, M | 1 |
| Tani, M | 1 |
| Hirao, Y | 1 |
| Minami, T | 1 |
| Kaneda, S | 1 |
| Otsuka, T | 1 |
| Jiao, Z | 1 |
| Shiao, YH | 1 |
| Ramakrishna, G | 1 |
| Anderson, LM | 1 |
| Perantoni, AO | 1 |
| Rice, JM | 3 |
| Diwan, BA | 3 |
| Schoental, R | 1 |
| Craddock, VM | 1 |
| Fridman-Manduzio, A | 1 |
| Gol-Winkler, R | 1 |
| Betz, EH | 1 |
| Goutier, R | 1 |
| Habs, M | 1 |
| Ivankovic, S | 1 |
| Iwata, C | 1 |
| Tanikake, T | 1 |
| Stewart, BW | 1 |
| Brian, MJ | 1 |
| Schweinsberg, F | 1 |
| Kouros, M | 1 |
| Manncke, K | 1 |
| Poound, AW | 1 |
| McGuire, LJ | 1 |
| Reznik, G | 1 |
| Mohr, U | 1 |
| Hakoi, K | 1 |
| Yada, H | 1 |
| Ito, M | 1 |
| Oyama, F | 1 |
| Titani, K | 1 |
| Ushijima, T | 1 |
| Nagao, M | 1 |
| Hirono, I | 1 |
| Sano, M | 1 |
| Asakawa, E | 1 |
| Tanaka, H | 1 |
| Nims, RW | 2 |
| Henneman, JR | 1 |
| Ward, JM | 2 |
| Lubet, RA | 2 |
| Nakamura, T | 1 |
| Dietrich, DR | 1 |
| Swenberg, JA | 2 |
| Nakamura, M | 1 |
| Nishii, S | 1 |
| Sano, N | 1 |
| Otsuka, H | 1 |
| Kinouchi, T | 1 |
| Ohnishi, Y | 1 |
| Short, BG | 1 |
| Steinhagen, WH | 1 |
| Moore, MA | 2 |
| Satoh, K | 2 |
| Tsuchida, S | 1 |
| Sato, K | 1 |
| Ichihara, A | 1 |
| Hacker, HJ | 1 |
| Katayama, H | 1 |
| Bannasch, P | 1 |
| Nogueira, E | 1 |
| Hu, H | 1 |
| Rosenberg, MR | 1 |
| Novicki, DL | 1 |
| Jirtle, RL | 1 |
| Novotny, A | 1 |
| Michalopoulos, G | 1 |
| Takamura, N | 2 |
| Matushima, Y | 1 |
| Imazawa, T | 2 |
| Huang, M | 1 |
| Wang, XQ | 1 |
| Wang, ZH | 1 |
| Zhou, CN | 1 |
| Wu, M | 1 |
| Inoue, T | 1 |
| Amelizad, Z | 1 |
| Oesch, F | 1 |
| Kurata, Y | 1 |
| Yamashita, T | 1 |
| Porta, EA | 1 |
| Dytioco, S | 1 |
| Aquino, T | 1 |
| Dorado, RD | 1 |
| Ooka, S | 1 |
| Markell, N | 1 |
| Aoki, S | 1 |
| Matsushima, Y | 1 |
| Lijinsky, W | 1 |
| Kovatch, RM | 1 |
84 other studies available for diethylnitrosamine and Cancer of Kidney
| Article | Year |
|---|---|
Pueraria montana (Kudzu vine) Ameliorate the Inflammation and Oxidative Stress against Fe-NTA Induced Renal Cancer.
Topics: Animals; Antioxidants; Biomarkers, Tumor; Body Weight; Creatinine; Cyclooxygenase 2; Diethylnitrosam | 2022 |
Madhuca longifolia Embedded Silver Nanoparticles Attenuate Diethylnitrosamine (DEN)-Induced Renal Cancer via Regulating Oxidative Stress.
Topics: Animals; Diethylnitrosamine; Kidney Neoplasms; Madhuca; Metal Nanoparticles; Oxidative Stress; Plant | 2021 |
The therapeutic potential of curcumin in alleviating N-diethylnitrosamine and iron nitrilotriacetate induced renal cell tumours in mice via inhibition of oxidative stress: Implications for cancer chemoprevention.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phy | 2021 |
Anti-carcinogenic effect of hesperidin against renal cell carcinoma by targeting COX-2/PGE2 pathway in Wistar rats.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinogenesis; Carcinoma, Renal Cell; Cell Prolifer | 2018 |
Anti-carcinogenic potential of Euphorbia neriifolia leaves and isolated flavonoid against N-nitrosodiethylamine-induced renal carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Body Weight; Carcinogenesis; Diethylnitrosamine | 2013 |
A medium-term gpt delta rat model as an in vivo system for analysis of renal carcinogenesis and the underlying mode of action.
Topics: Animals; Carcinogenesis; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Disease Models, Ani | 2015 |
Novel glycoside from Wedelia calendulacea inhibits diethyl nitrosamine-induced renal cancer via downregulating the COX-2 and PEG
Topics: Animals; Cyclooxygenase 2; Diethylnitrosamine; Dinoprostone; Dose-Response Relationship, Drug; Down- | 2017 |
Potassium bromate enhances N-ethyl-N-hydroxyethylnitrosamine-induced kidney carcinogenesis only at high doses in Wistar rats: indication of the existence of an enhancement threshold.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Body Weight; Bromates; Carcinogens; Deoxyguanosine; Diethylnit | 2009 |
Chemopreventive effect of hydroethanolic extract of Euphorbia neriifolia leaves against DENA-induced renal carcinogenesis in mice.
Topics: Alkylating Agents; Animals; Antioxidants; Catalase; Diethylnitrosamine; Ethanol; Euphorbia; Kidney N | 2011 |
Characterization of N-diethylnitrosamine-initiated and ferric nitrilotriacetate-promoted renal cell carcinoma experimental model and effect of a tamarind seed extract against acute nephrotoxicity and carcinogenesis.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Cell Transformation, Neoplastic; Diethylnitrosamine; Di | 2012 |
Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-κB.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Cell Proliferation; Cyclooxygenase 2; Cytokines; Diethy | 2013 |
N-ethyl-N-hydroxyethylnitrosamine (EHEN)-induced renal and hepatocarcinogenesis in the tumor suppressor Tsc2 transgenic rat.
Topics: Animals; Animals, Genetically Modified; Carcinogens; Diethylnitrosamine; Female; Gene Expression Reg | 2002 |
INDUCTION OF MALIGNANT TUMORS IN VARIOUS STRAINS OF MICE BY ORAL ADMINISTRATION OF N-NITROSODIMETHYLAMINE AND N-NITROSODIETHYLAMINE.
Topics: Adenocarcinoma; Adenoma; Administration, Oral; Animals; Carcinogens; Diethylnitrosamine; Dimethylnit | 1965 |
Chemomodulatory effect of Ficus racemosa extract against chemically induced renal carcinogenesis and oxidative damage response in Wistar rats.
Topics: Animals; Blood Urea Nitrogen; Catalase; Chelating Agents; Chromatography, High Pressure Liquid; Chro | 2005 |
Etiology of bromate-induced cancer and possible modes of action-studies in Japan.
Topics: Administration, Oral; Alpha-Globulins; Animals; Bromates; Carcinogens, Environmental; Carcinoma, Ren | 2006 |
Histopathological and biochemical analyses of transplantable renal adenocarcinoma in rats induced by N-ethyl-N-hydroxyethylnitrosamine.
Topics: Adenocarcinoma; Animals; Carcinogens; Diethylnitrosamine; gamma-Glutamyltransferase; Kidney Neoplasm | 1984 |
Modifying effects of butylated hydroxyanisole, ethoxyquin and acetaminophen on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine.
Topics: Acetaminophen; Adenocarcinoma; Animals; Anisoles; Butylated Hydroxyanisole; Carcinogens; Diethylnitr | 1984 |
Modification of carcinogenesis by antioxidants and other compounds.
Topics: Acetaminophen; Animals; Antioxidants; Body Weight; Butylated Hydroxyanisole; Carcinogens; Diethylnit | 1984 |
DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats.
Topics: Animals; Body Weight; Carcinogens; Diethylnitrosamine; Drug Synergism; Kidney; Kidney Neoplasms; Mal | 1984 |
Basic lead acetate: promoting effect on the development of renal tubular cell tumors in rats treated with N-ethyl-N-hydroxyethylnitrosamine.
Topics: Animals; Carcinogens; Diethylnitrosamine; Drug Synergism; Kidney Neoplasms; Lead; Male; Neoplasms, E | 1983 |
Promotion of 2-(ethylnitrosamino)ethanol-induced renal carcinogenesis in rats by nephrotoxic compounds: positive responses with folic acid, basic lead acetate, and N-(3,5-dichlorophenyl)succinimide but not with 2,3-dibromo-1-propanol phosphate.
Topics: Animals; Body Weight; Carcinogens; Diethylnitrosamine; Folic Acid; Kidney Neoplasms; Lead; Male; Nit | 1984 |
Trisodium nitrilotriacetate monohydrate: promoting effects on the development of renal tubular cell tumors in rats treated with N-ethyl-N-hydroxyethylnitrosamine.
Topics: Acetates; Animals; Body Weight; Carcinogens; Diet; Diethylnitrosamine; Drug Synergism; Kidney Neopla | 1984 |
Enhancement by potassium bromate of renal tumorigenesis initiated by N-ethyl-N-hydroxyethylnitrosamine in F-344 rats.
Topics: Animals; Bromates; Bromine; Diethylnitrosamine; Food Additives; Kidney Neoplasms; Male; Nitrosamines | 1983 |
Tumorigenic effect of sodium arsenite in rat kidney.
Topics: Animals; Arsenic; Arsenites; Body Weight; Carcinogens; Diethylnitrosamine; Hepatectomy; Kidney Neopl | 1983 |
Effect of phenobarbital, polychlorinated biphenyl and sodium saccharin on hepatic and renal carcinogenesis in unilaterally nephrectomized rats given N-ethyl-N-hydroxyethylnitrosamine orally.
Topics: Animals; Carcinogens; Diethylnitrosamine; Kidney Neoplasms; Liver Neoplasms; Male; Neoplasms, Experi | 1981 |
Carcinogenic activity of N-nitrosodiethylamine in snakes.
Topics: Animals; Diethylnitrosamine; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Mouth; Mouth Neoplasm | 1983 |
Sequential observations on the appearance of neoplastic lesions in the liver and kidney after treatment with N-ethyl-N-hydroxyethylnitrosamine followed by partial hepatectomy and unilateral nephrectomy.
Topics: Animals; Carcinogens; Diethylnitrosamine; Hepatectomy; Kidney Neoplasms; Liver Neoplasms; Male; Neop | 1983 |
beta-Cyclodextrin: promoting effect on the development of renal tubular cell tumors in rats treated with N-ethyl-N-hydroxyethylnitrosamine.
Topics: Animals; beta-Cyclodextrins; Body Weight; Carcinogens; Cocarcinogenesis; Cyclodextrins; Dextrins; Di | 1982 |
Inhibitory effect of 4,4'-diaminodiphenylmethane on liver, kidney and bladder carcinogenesis in rats ingesting N-ethyl-N-hydroxyethylnitrosamine or N-butyl-N-(4-hydroxybutyl) nitros-amine.
Topics: Aniline Compounds; Animals; Benzhydryl Compounds; Butylhydroxybutylnitrosamine; Carcinogens; Diethyl | 1981 |
Comparison of the effects of tamoxifen and toremifene on liver and kidney tumor promotion in female rats.
Topics: Adenosine Triphosphatases; Animals; Carcinogens; Diethylnitrosamine; Female; gamma-Glutamyltransfera | 1995 |
Modulating effects of ellagic acid, vanillin and quercetin in a rat medium term multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Animals; Benzaldehydes; Butylhydroxybutylnitrosamine; Diethylnitrosamine; Dim | 1995 |
Inhibitory effect of potassium citrate on rat renal tumors induced by N-ethyl-N-hydroxyethylnitrosamine followed by potassium dibasic phosphate.
Topics: Alpha-Globulins; Animals; Body Weight; Calcium; Citrates; Citric Acid; Diethylnitrosamine; Kidney; K | 1993 |
Modification of hepato- and renal carcinogenesis by catechol and its isomers in rats pretreated with N-ethyl-N-hydroxyethylnitrosamine.
Topics: Adenoma; Administration, Oral; Alpha-Globulins; Animals; Body Weight; Carcinoma, Renal Cell; Catecho | 1993 |
Initiation-stage enhancement by uracil of N-ethyl-N-hydroxyethylnitrosamine-induction of kidney carcinogenesis in rats.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinogens; Diethylnitrosamine; Drug Synergism; Female; Kidne | 1994 |
Elevated concentrations of the beta-subunit of S100 protein in renal cell tumors in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Renal Cell; Diethylnitrosamine; Femal | 1994 |
Growth hormone administration after treatment in the resistant hepatocyte model does not affect progression of rat liver carcinogenesis.
Topics: 2-Acetylaminofluorene; Androstenedione; Animals; Body Weight; Cell Division; Diethylnitrosamine; Fem | 1994 |
Enhanced neoplastic lesion development with adenine-induced experimental multicystic nephropathy by adenine--a model system for the analysis of renal tumor generation in long-term hemodialysis patients.
Topics: Adenine; Adenoma; Animals; Diethylnitrosamine; Epithelium; Hyperplasia; Kidney Diseases; Kidney Neop | 1994 |
Strain and sex differences in kidney carcinogenesis in rats treated with N-ethyl-N-hydroxyethylnitrosamine and uracil.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Diethylnitrosamine; Female; Kidney Neoplasms; Male; R | 1995 |
Lack of chemoprevention effects of the monoterpene d-limonene in a rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carc | 1996 |
Somatic mutation of the tuberous sclerosis (Tsc2) tumor suppressor gene in chemically induced rat renal carcinoma cell.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Diethylnitrosamine; Genes, Tumor Suppressor; Kidney Neo | 1997 |
Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rat: implications for the involvement of oxidative stress.
Topics: Adenocarcinoma; Animals; Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Carcinoge | 1998 |
Biallelic mutations of the Tsc2 gene in chemically induced rat renal cell carcinoma.
Topics: Alleles; Animals; Carcinogens; Carcinoma, Renal Cell; Diethylnitrosamine; DNA Primers; Exons; Kidney | 1998 |
Copper-nitrilotriacetate (Cu-NTA) is a potent inducer of proliferative response both in liver and kidney but is a complete renal carcinogen.
Topics: Animals; Carcinogens; Cell Division; Diethylnitrosamine; Kidney Neoplasms; Liver Neoplasms; Male; Mi | 1999 |
Effect of polyphenon-60 on the development of renal cell tumors in rats treated with N-ethyl-N hydroxyethylnitrosamine.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Renal Cell; Catechin; Diethylnitrosamine; | 1999 |
Nordihydroguairetic acid is a potent inhibitor of ferric-nitrilotriacetate-mediated hepatic and renal toxicity, and renal tumour promotion, in mice.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Blood Urea Nitrogen; Carcinogens; Catalase; Creatini | 1999 |
Identification of a locus for susceptibility to renal cell carcinoma in the Long-Evans Cinnamon rat.
Topics: Alkylating Agents; Animals; Carcinoma, Renal Cell; Chromosome Mapping; Crosses, Genetic; Diethylnitr | 1999 |
Concurrent administration of fish meal and sodium nitrite does not promote renal carcinogenesis in rats after initiation with N-ethyl-N-hydroxyethylnitrosamine.
Topics: Adenocarcinoma; Adenoma; Adrenal Glands; Animals; Body Weight; Cocarcinogenesis; Diet; Diethylnitros | 2000 |
Prevention of renal cell carcinoma by active vitamin D3.
Topics: Adult; Aged; Carcinogens; Carcinoma, Renal Cell; Cholecalciferol; Diethylnitrosamine; Female; Gap Ju | 2000 |
Establishment and characterization of three new rat renal cell carcinoma cell lines from N-ethyl-N-hydroxyethylnitrosamine-induced basophilic cell tumors.
Topics: Animals; Carcinoma, Renal Cell; Cell Culture Techniques; Diethylnitrosamine; Immunohistochemistry; K | 2001 |
Strain variation in renal carcinogenesis by N-ethyl-N-hydroxyethylnitrosamine in F1 (Wistar-Fischer) rats.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Disease Models, Animal; Female; Gen | 2001 |
Role of Atp7b gene in spontaneous and N-diethylnitrosamine-induced carcinogenesis in a new congenic strain, WKAH.C-Atp7b rats.
Topics: Adenosine Triphosphatases; Animals; Body Weight; Carcinogenicity Tests; Carcinoma, Hepatocellular; C | 2001 |
Down-regulation of von Hippel-Lindau protein in N-nitroso compound-induced rat non-clear cell renal tumors.
Topics: Adenocarcinoma; Animals; Blotting, Western; Carcinogens; Diethylnitrosamine; DNA Mutational Analysis | 2002 |
The role of nicotinamide and of certain other modifying factors in diethylnitrosamine carcinogenesis: fusaria mycotoxins and "spontaneous" tumors in animals and man.
Topics: Animals; Diethylnitrosamine; Female; Fusarium; Gastrointestinal Neoplasms; Genital Neoplasms, Female | 1977 |
Effect of a single treatment with the alkylating carcinogens dimethynitrosamine, diethylnitrosamine and methyl methanesulphonate, on liver regenerating after partial hepatectomy. I. Test for induction of liver carcinomas.
Topics: Adenocarcinoma; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Dimethylnitrosamine; Female; | 1975 |
Tumor frequency and characteristics after a single dose of dimethylnitrosamine or diethylnitrosamine in partially hepatectomized rats.
Topics: Adenocarcinoma; Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Dimethyl | 1977 |
Carcinogenesis of N-nitrosodiethylamine (DENA) in chickens and domestic cats.
Topics: Adenocarcinoma; Administration, Oral; Animals; Animals, Domestic; Carcinogens; Carcinoma, Hepatocell | 1978 |
Histopathological studies on renal tubular cell tumors in rats treated with N-ethyl-N-hydroxyethylnitrosamine.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Diethylnitrosamine; Kidney; Kidney Neoplasms; Kidne | 1979 |
Evidence of carcinogen-induced replication of partially-repaired DNA in target cells during nitrosamine carcinogenesis.
Topics: Animals; Chromatography, DEAE-Cellulose; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; DNA Re | 1979 |
[Comparative investigations on the organotropic carcinogenic effect of different N-nitroso compounds with rat after single and chronic treatment (author's transl)].
Topics: Animals; Benzyl Compounds; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Female; Ki | 1979 |
Influence of repeated liver regeneration on hepatic carcinogenesis by diethylnitrosamine in mice.
Topics: Animals; Carbon Tetrachloride; Diethylnitrosamine; Kidney Neoplasms; Liver Neoplasms; Liver Regenera | 1978 |
Induction of renal pelvic tumours in Sprague-Dawley rats by di-isopropanolnitrosamine.
Topics: Animals; Carcinoma, Transitional Cell; Diethylnitrosamine; Female; Kidney Neoplasms; Male; Neoplasms | 1976 |
Enhancing effects of diallyl sulfide on hepatocarcinogenesis and inhibitory actions of the related diallyl disulfide on colon and renal carcinogenesis in rats.
Topics: Allyl Compounds; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Diethylnitrosamine; Disulfide | 1992 |
Absence of ras family point mutations at codons 12, 13 and 61 in N-ethyl-N-hydroxyethylnitrosamine- or N-nitrosomorpholine-induced renal cell tumors in rats.
Topics: Adenoma; Animals; Base Sequence; Carcinogens; Carcinoma, Renal Cell; Diethylnitrosamine; Exons; Gene | 1992 |
Enhancing effects of harman and norharman on induction of preneoplastic and neoplastic kidney lesions in rats initiated with N-ethyl-N-hydroxyethylnitrosamine.
Topics: Animals; Carbolines; Carcinogens; Carcinoma, Renal Cell; Diethylnitrosamine; Harmine; Kidney Neoplas | 1992 |
Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid on N-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat.
Topics: Animals; Barbiturates; Body Weight; Cocarcinogenesis; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzy | 1992 |
Promoting effects of potassium dibasic phosphate on early-stage renal carcinogenesis in unilaterally nephrectomized rats treated with N-ethyl-N-hydroxyethylnitrosamine.
Topics: Animals; Body Weight; Bromodeoxyuridine; Carcinogens; Carcinoma, Renal Cell; Copper; Copper Sulfate; | 1992 |
The presence of alpha 2u-globulin is necessary for d-limonene promotion of male rat kidney tumors.
Topics: Adenoma; Alpha-Globulins; Animals; Body Weight; Carcinogens; Cell Division; Cyclohexenes; Diethylnit | 1991 |
Possible application to medium-term organ bioassays for renal carcinogenesis modifiers in rats treated with N-ethyl-N-hydroxyethylnitrosamine and unilateral nephrectomy.
Topics: Animals; Bromodeoxyuridine; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Drug Synergism; | 1991 |
Tumor promoting potential in male F344 rats and mutagenicity in Salmonella typhimurium of dipyrone.
Topics: Animals; Body Weight; Diethylnitrosamine; Dipyrone; Dose-Response Relationship, Drug; Drinking; Kidn | 1991 |
Promoting effects of unleaded gasoline and 2,2,4-trimethylpentane on the development of atypical cell foci and renal tubular cell tumors in rats exposed to N-ethyl-N-hydroxyethylnitrosamine.
Topics: Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, Drug; Drug Synergism; Female; | 1989 |
Comparison of the various forms of glutathione S-transferase with glucose-6-phosphate dehydrogenase and gamma-glutamyltranspeptidase as markers of preneoplastic and neoplastic lesions in rat kidney induced by N-ethyl-N-hydroxyethylnitrosamine.
Topics: Adenoma; Animals; Carcinogens; Diethylnitrosamine; gamma-Glutamyltransferase; Glucosephosphate Dehyd | 1985 |
Correlative histochemical studies on preneoplastic and neoplastic lesions in the kidney of rats treated with nitrosamines.
Topics: Animals; Carcinogens; Diethylnitrosamine; Glycolysis; Kidney; Kidney Neoplasms; Male; Nitrosamines; | 1986 |
Rat renal carcinogenesis after chronic simultaneous exposure to lead acetate and N-nitrosodiethylamine.
Topics: Animals; Cocarcinogenesis; Diethylnitrosamine; Kidney Neoplasms; Male; Organometallic Compounds; Rat | 1987 |
Tumor promoting activities of ethylphenylacetylurea and diethylacetylurea, the ring hydrolysis products of barbiturate tumor promoters phenobarbital and barbital, in rat liver and kidney initiated by N-nitrosodiethylamine.
Topics: Animals; Barbital; Body Weight; Carcinogens; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enz | 1989 |
Promoting effect of nicotinamide on the development of renal tubular cell tumors in rats initiated with diethylnitrosamine.
Topics: Animals; Body Weight; Cocarcinogenesis; Diethylnitrosamine; Kidney Neoplasms; Kidney Tubules; Male; | 1985 |
Promoting effect of peroxisome proliferators in two-stage rat renal tumorigenesis.
Topics: Animals; Clofibrate; Cocarcinogenesis; Diethylhexyl Phthalate; Diethylnitrosamine; Kidney Neoplasms; | 1988 |
The studies of malignant transformation of human epithelial cells induced by diethyl-nitrosamine (NDEA) in vitro.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosamine; Epithelial Cells; Fet | 1986 |
Immunohistochemically demonstrated altered expression of cytochrome P-450 molecular forms and epoxide hydrolase in N-ethyl-N-hydroxyethylnitrosamine-induced rat kidney and liver lesions.
Topics: Animals; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Epoxide Hydrolases; Glutathione Transfe | 1987 |
Reciprocal modifying effects of isomeric forms of aminophenol on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine.
Topics: Acetaminophen; Aminophenols; Animals; Body Weight; Diethylnitrosamine; Glutathione Transferase; Kidn | 1987 |
Evaluation of the effect of glucan on hepatic, renal and mammary tumorigenesis in rats.
Topics: Animals; Diethylnitrosamine; Female; Glucans; Glucose; Hepatectomy; Kidney Neoplasms; Liver Neoplasm | 1986 |
Organ specific modifying potential of ethinyl estradiol on carcinogenesis initiated with different carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Interactio | 1987 |
Dose-related enhancing effect of potassium bromate on renal tumorigenesis in rats initiated with N-ethyl-N-hydroxyethyl-nitrosamine.
Topics: Animals; Bromates; Bromine; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Dose-Response Relatio | 1985 |
Dose-related effect of trisodium nitrilotriacetate monohydrate on renal tumorigenesis initiated with N-ethyl-N-hydroxyethylnitrosamine in rats.
Topics: Acetates; Animals; Carcinogens; Carcinoma, Renal Cell; Diethylnitrosamine; Dose-Response Relationshi | 1985 |
Induction of liver tumors in rats by nitrosodiethanolamine at low doses.
Topics: Animals; Carcinogens; Diethylnitrosamine; Female; Kidney Neoplasms; Liver Neoplasms; Liver Neoplasms | 1985 |