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diethylnitrosamine and Bile Duct Neoplasms

diethylnitrosamine has been researched along with Bile Duct Neoplasms in 7 studies

Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.

Bile Duct Neoplasms: Tumors or cancer of the BILE DUCTS.

Research Excerpts

ExcerptRelevanceReference
" We studied mice with bile-duct ligation, orthotopic cholangiocarcinomas, cholestasis-induced cholangiocarcinoma, diethylnitrosamine-induced liver tumors, and xenograft tumors."3.88Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer. ( Annamalai, A; Fan, W; Li, TWH; Liu, T; Liu, Z; Lu, SC; Maldonado, SS; Mato, JM; Noureddin, M; Seki, E; Shen, H; Steggerda, J; Tu, J; Wang, J; Xiong, T; Yang, H; Yang, J, 2018)
"To induce chronic cholestasis, Balb/c mice were given 2 weekly intraperitoneal injections of diethylnitrosamine (DEN); 2 weeks later, some mice also received left and median bile duct ligation (LMBDL) and, then 1 week later, were fed DEN, in corn oil, weekly by oral gavage (DLD)."3.77A mouse model of cholestasis-associated cholangiocarcinoma and transcription factors involved in progression. ( Aller, MA; Ko, KS; Li, TW; Peng, J; Tang, X; Xia, M; Yang, H, 2011)
" The principal aim was to characterize the dose-response relationship for the effects of these agents on esophageal cancer (NDEA) or on various types of liver cancer (NDEA and NDMA), although NDEA also caused a few tumors of the nasopharynx and NDMA also caused a few tumors of the lung."1.28Effects on 4080 rats of chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine: a detailed dose-response study. ( Brantom, P; Grasso, P; Gray, R; Peto, R, 1991)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, T1
Yang, H2
Fan, W1
Tu, J1
Li, TWH1
Wang, J1
Shen, H1
Yang, J1
Xiong, T1
Steggerda, J1
Liu, Z1
Noureddin, M1
Maldonado, SS1
Annamalai, A1
Seki, E1
Mato, JM1
Lu, SC1
Mu, X1
Pradere, JP1
Affò, S1
Dapito, DH1
Friedman, R1
Lefkovitch, JH1
Schwabe, RF1
Li, TW1
Peng, J1
Tang, X1
Ko, KS1
Xia, M1
Aller, MA1
Heindryckx, F1
Kuchnio, A1
Casteleyn, C1
Coulon, S1
Olievier, K1
Colle, I1
Geerts, A1
Libbrecht, L1
Carmeliet, P1
Van Vlierberghe, H1
Dill, MT1
Tornillo, L1
Fritzius, T1
Terracciano, L1
Semela, D1
Bettler, B1
Heim, MH1
Tchorz, JS1
Mikol, YB1
Hoover, KL1
Creasia, D1
Poirier, LA1
Peto, R1
Gray, R1
Brantom, P1
Grasso, P1

Other Studies

7 other studies available for diethylnitrosamine and Bile Duct Neoplasms

ArticleYear
Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer.
    Gastroenterology, 2018, Volume: 155, Issue:2

    Topics: Animals; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholangiocarcinoma; Chole

2018
Epithelial Transforming Growth Factor-β Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma.
    Gastroenterology, 2016, Volume: 150, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4;

2016
A mouse model of cholestasis-associated cholangiocarcinoma and transcription factors involved in progression.
    Gastroenterology, 2011, Volume: 141, Issue:1

    Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Basic Helix-Loop-Helix Transcr

2011
Effect of prolyl hydroxylase domain-2 haplodeficiency on the hepatocarcinogenesis in mice.
    Journal of hepatology, 2012, Volume: 57, Issue:1

    Topics: Alkylating Agents; Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular

2012
Constitutive Notch2 signaling induces hepatic tumors in mice.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:4

    Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cell Differentiat

2013
Hepatocarcinogenesis in rats fed methyl-deficient, amino acid-defined diets.
    Carcinogenesis, 1983, Volume: 4, Issue:12

    Topics: Adenoma, Bile Duct; Amino Acids; Animals; Bile Duct Neoplasms; Choline Deficiency; Diet; Diethylnitr

1983
Effects on 4080 rats of chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine: a detailed dose-response study.
    Cancer research, 1991, Dec-01, Volume: 51, Issue:23 Pt 2

    Topics: Animals; Bile Duct Neoplasms; Carcinogenicity Tests; Diethylnitrosamine; Dimethylnitrosamine; Dose-R

1991