diethylnitrosamine has been researched along with Adenoma, Hepatocellular in 15 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Furthermore, Shp2 ablation dramatically enhanced diethylnitrosamine (DEN)-induced hepatocellular carcinoma (HCC) development, which was abolished by concurrent deletion of Shp2 and Stat3 in hepatocytes." | 3.77 | Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis. ( Bailly-Maitre, B; Bard-Chapeau, EA; Ding, J; Fang, DD; Feng, GS; Han, T; Li, S; Poli, V; Princen, F; Varki, NM; Wang, H; Zhang, SS; Zhu, HH, 2011) |
| "Diethylnitrosamine-treated TT mice developed both preneoplastic and neoplastic lesions in the liver." | 1.31 | Enhancement of chemical hepatocarcinogenesis by the HIV-1 tat gene. ( Altavilla, G; Barbanti-Brodano, G; Caputo, A; Corallini, A; Lanfredi, M; Piola, C, 2000) |
| "The average numbers of liver neoplasms in groups 2 and 3 were significantly smaller than in group 1 (P < 0." | 1.31 | Chemopreventive effects of scordinin on diethylnitrosamine and phenobarbital-induced hepatocarcinogenesis in male F344 rats. ( Mori, H; Okamoto, K; Rahman, KM; Sugie, S; Ushida, J; Watanabe, T, 2001) |
| "Trichloroethylene (TCE) was found as a contaminant in the well supplying water to an aquatic testing laboratory." | 1.30 | Environmental complex mixture toxicity assessment. ( Boncavage-Hennessey, EM; Brennan, LM; Gardner, HS; Rosencrance, AB; Toussaint, MW; Wolfe, MJ, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 8 (53.33) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maeda, J | 1 |
| Inoue, K | 1 |
| Ichimura, R | 1 |
| Takahashi, M | 1 |
| Kodama, Y | 1 |
| Saito, N | 1 |
| Yoshida, M | 1 |
| Youn, P | 1 |
| Kim, S | 1 |
| Ahn, JH | 1 |
| Kim, Y | 1 |
| Park, JD | 1 |
| Ryu, DY | 1 |
| Dewa, Y | 1 |
| Nishimura, J | 1 |
| Jin, M | 1 |
| Kawai, M | 1 |
| Saegusa, Y | 1 |
| Kenmochi, S | 1 |
| Shimamoto, K | 1 |
| Harada, T | 1 |
| Shibutani, M | 1 |
| Mitsumori, K | 1 |
| Bard-Chapeau, EA | 1 |
| Li, S | 1 |
| Ding, J | 1 |
| Zhang, SS | 1 |
| Zhu, HH | 1 |
| Princen, F | 1 |
| Fang, DD | 1 |
| Han, T | 1 |
| Bailly-Maitre, B | 1 |
| Poli, V | 1 |
| Varki, NM | 1 |
| Wang, H | 1 |
| Feng, GS | 1 |
| Zhu, H | 1 |
| Wang, Y | 1 |
| Chen, J | 1 |
| Cheng, G | 1 |
| Xue, J | 1 |
| González de Mejía, E | 1 |
| Ramírez-Mares, MV | 1 |
| Arce-Popoca, E | 1 |
| Wallig, M | 1 |
| Villa-Treviño, S | 1 |
| Espandiari, P | 1 |
| Glauert, HP | 2 |
| Lehmler, HJ | 1 |
| Lee, EY | 2 |
| Srinivasan, C | 1 |
| Robertson, LW | 1 |
| Eyigor, A | 1 |
| Tharappel, JC | 1 |
| Cooper, S | 1 |
| Spear, BT | 1 |
| Lee, TY | 1 |
| Kim, KT | 1 |
| Han, SY | 1 |
| Hambali, Z | 1 |
| Ngah, WZ | 1 |
| Wahid, SA | 1 |
| Kadir, KA | 1 |
| Klaunig, JE | 1 |
| Weghorst, CM | 1 |
| Devor, DE | 1 |
| Henneman, JR | 1 |
| Ward, JM | 1 |
| Gardner, HS | 1 |
| Brennan, LM | 1 |
| Toussaint, MW | 1 |
| Rosencrance, AB | 1 |
| Boncavage-Hennessey, EM | 1 |
| Wolfe, MJ | 1 |
| Altavilla, G | 1 |
| Caputo, A | 1 |
| Lanfredi, M | 1 |
| Piola, C | 1 |
| Barbanti-Brodano, G | 1 |
| Corallini, A | 1 |
| Watanabe, T | 1 |
| Sugie, S | 1 |
| Okamoto, K | 1 |
| Rahman, KM | 1 |
| Ushida, J | 1 |
| Mori, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Biomarker Analyses in Hepatocellular Carcinoma Patients Treated With Therasphere®[NCT03203837] | 4 participants (Actual) | Observational | 2017-07-05 | Terminated (stopped due to Funding Discontinued due to low accrual rate) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 other studies available for diethylnitrosamine and Adenoma, Hepatocellular
| Article | Year |
|---|---|
Essential role of constitutive androstane receptor in Ginkgo biloba extract induced liver hypertrophy and hepatocarcinogenesis.
Topics: Adenoma, Liver Cell; Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cocarcinogenesis; Constitu | 2015 |
Regulation of iron metabolism-related genes in diethylnitrosamine-induced mouse liver tumors.
Topics: Adenoma, Liver Cell; Animals; Antimicrobial Cationic Peptides; Cation Transport Proteins; Ceruloplas | 2009 |
Immunohistochemical analyses at the late stage of tumor promotion by oxfendazole in a rat hepatocarcinogenesis model.
Topics: Adenoma, Liver Cell; Animals; Anthelmintics; Apoptosis; Benzimidazoles; Carcinogens; Cell Cycle Prot | 2011 |
Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis.
Topics: Adenoma, Liver Cell; Animals; Carcinoma, Hepatocellular; Cytokines; Diethylnitrosamine; Gene Express | 2011 |
Transgenic mice expressing hepatitis B virus X protein are more susceptible to carcinogen induced hepatocarcinogenesis.
Topics: Adenoma, Liver Cell; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma, Hepatocellular; Diethyl | 2004 |
Inhibition of liver carcinogenesis in Wistar rats by consumption of an aqueous extract from leaves of Ardisia compressa.
Topics: 2-Acetylaminofluorene; Adenoma, Liver Cell; Animals; Antineoplastic Agents; Ardisia; Carcinogens; Ca | 2004 |
Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model.
Topics: 2-Acetylaminofluorene; Adenoma, Liver Cell; Administration, Oral; Animals; Biphenyl Compounds; Body | 2004 |
Inhibition of hepatocarcinogenesis by the deletion of the p50 subunit of NF-kappaB in mice administered the peroxisome proliferator Wy-14,643.
Topics: Acyl-CoA Oxidase; Adenoma, Liver Cell; Animals; Apoptosis; Carcinogens; Cell Proliferation; Diethyln | 2006 |
Expression of ErbB receptor proteins and TGF-alpha during diethylnitrosamine-induced hepatocarcinogenesis in the rat liver.
Topics: Adenoma, Liver Cell; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; ErbB Receptors; Glutath | 2007 |
Effect of ovariectomy and sex hormone replacement on glutathione and glutathione-related enzymes in rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Adenoma, Liver Cell; Animals; Diethylnitrosamine; Estradiol; Female; Glutathi | 1995 |
Selective induction of DNA synthesis in mouse preneoplastic and neoplastic hepatic lesions after exposure to phenobarbital.
Topics: Adenoma, Liver Cell; Animals; Cocarcinogenesis; Diethylnitrosamine; DNA, Neoplasm; Liver; Liver Neop | 1993 |
Promotion of hepatocellular foci and adenomas by di(2-ethylhexyl) phthalate and phenobarbital in C3H/HeNCr mice following exposure to N-nitrosodiethylamine at 15 days of age.
Topics: Adenoma, Liver Cell; Animals; Diethylhexyl Phthalate; Diethylnitrosamine; Disease Models, Animal; Fe | 1994 |
Environmental complex mixture toxicity assessment.
Topics: Adenoma, Liver Cell; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma, Hepatocellular; Chromat | 1998 |
Enhancement of chemical hepatocarcinogenesis by the HIV-1 tat gene.
Topics: Adenoma, Liver Cell; Animals; Basophils; Carcinogens; Carcinoma, Hepatocellular; Diethylnitrosamine; | 2000 |
Chemopreventive effects of scordinin on diethylnitrosamine and phenobarbital-induced hepatocarcinogenesis in male F344 rats.
Topics: Adenoma, Liver Cell; Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Carcinoma, Hepatoce | 2001 |