diethylnitrosamine has been researched along with Adenoma, Basal Cell in 81 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we set up a rat model of diethylnitrosamine (DEN) induced pulmonary adenoma to evaluate the antitumor effects of RPS again." | 7.81 | Inhibition of pulmonary adenoma in diethylnitrosamine-induced rats by Rhizoma paridis saponins. ( Chai, H; Fan, W; Gao, W; Li, J; Liu, Z; Man, S, 2015) |
| " Treatment with 2500 ppm ACI for 26 weeks after initiation with diethylnitrosamine increased the incidence and multiplicities of altered foci and adenomas in hepatocytes from WT mice; these effects were significantly reduced in CARKO mice." | 3.83 | Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development. ( Ichimura, R; Inoue, K; Kodama, Y; Kuwata, K; Shibutani, M; Takahashi, M; Yoshida, M, 2016) |
| "The purpose of this study was to reduce the time to tumor onset in a diethylnitrosamine (DEN)-induced hepatocellular carcinoma (HCC) swine model via partial liver embolization (PLE) and to characterize the model for use in translational research." | 3.83 | Validation of a Preclinical Model of Diethylnitrosamine-Induced Hepatic Neoplasia in Yucatan Miniature Pigs. ( Amin, HM; Avritscher, R; Cressman, E; Eskandari, G; Kaseb, AO; Konnath George, S; Mitchell, J; Morris, JS; Rashid, A; Tinkey, PT; Uthamanthil, R; Van Pelt, C; Xiao, L, 2016) |
| " In the present study, we set up a rat model of diethylnitrosamine (DEN) induced pulmonary adenoma to evaluate the antitumor effects of RPS again." | 3.81 | Inhibition of pulmonary adenoma in diethylnitrosamine-induced rats by Rhizoma paridis saponins. ( Chai, H; Fan, W; Gao, W; Li, J; Liu, Z; Man, S, 2015) |
| " Glutathione S-transferase placental (GST-P)-negative hepatocellular altered foci (HAF), hepatocellular adenoma (HCA), and hepatocellular carcinoma (HCC) were generated by two initiation-promotion models with N-nitrosodiethylamine (NDEN) and peroxisome proliferators, Wy-14,643 and clofibrate." | 3.72 | alpha(2)-Macroglobulin: a novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers. ( Fukushima, S; Kikuchi, K; Kushida, M; Mikami, N; Morimura, K; Oeda, K; Okuno, Y; Ozaki, K; Saito, K; Sukata, T; Sumida, K; Uwagawa, S, 2004) |
| " After application of diethylnitrosamine (DEN) preneoplastic foci and adenomas emerged in liver tissue of wild-type and phosphoenolpyruvate carboxykinase (PEPCK)-IGF-II transgenic mice." | 3.71 | Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice. ( Deml, E; Gittner, K; Hoeflich, A; Krebs, O; Lahm, H; Oesterle, D; Sprague, L; Wanke, R; Wolf, E, 2002) |
| "The ability of diethylnitrosamine (DENA) to initiate and phenobarbital to promote altered-hepatocyte foci and hepatocellular carcinomas in C3H and C3B6F1 (C3H x C57BL/6) mice was compared to the extent of cell proliferation." | 3.68 | Comparison in C3H and C3B6F1 mice of the sensitivity to diethylnitrosamine-initiation and phenobarbital-promotion to the extent of cell proliferation. ( Pereira, MA, 1993) |
| "The prevalence of Ki-ras, Ha-ras and N-ras point mutation within exons 1 and 2 was studied in 17 cases of renal cell tumors (8 carcinomas and 9 adenomas) induced by N-ethyl-N-hydroxyethyl-nitrosamine or N-nitrosomorpholine." | 3.68 | Absence of ras family point mutations at codons 12, 13 and 61 in N-ethyl-N-hydroxyethylnitrosamine- or N-nitrosomorpholine-induced renal cell tumors in rats. ( Hirono, I; Ito, M; Iwase, T; Matsumoto, K; Nagao, M; Nishida, Y; Oyama, F; Titani, K; Tsuda, H; Ushijima, T, 1992) |
| "Exposure of female hepatitis B virus transgenic mice of lineage 50-4, which display liver injury secondary to overexpression of the gene for the large envelope polypeptide of hepatitis B virus, to the hepatocarcinogens aflatoxin and diethylnitrosamine produced more rapid and extensive evidence of nodule formation and oval cell proliferation, as well as the development of adenomas and primary hepatocellular carcinomas, than was seen in transgenic mice not exposed to carcinogens." | 3.68 | Synergy between hepatitis B virus expression and chemical hepatocarcinogens in transgenic mice. ( Chisari, FV; Dunsford, HA; Hunt, JM; Sell, S, 1991) |
| " Two types of areas composed of basophilic or glycogenotic hepatocytes were observed preceding the appearance of hepatocellular adenomas and carcinomas." | 3.68 | Rat hepatocarcinogenesis induced by N-nitrosodiethylamine and N-nitrosomorpholine continuously administered at low doses. From basophilic areas of hepatocytes to hepatocellular tumors. ( Cortinovis, C; Klimek, F; Nogueira, E, 1991) |
| "In a study on lung adenomas induced by the administration of a single intragastric dose of sodium thiocyanate, diethylnitrosamine, or its precursors to 15-day-old C57BLxC3H F1 mice the occurrence of crystalline inclusions in pulmonary parenchyma was noted." | 3.67 | Crystalline inclusions associated with lung adenomas in C57BLxC3H F1 mice. ( Abrahams, C; Ghose, T; Rijhsinghani, KS; Swerdlow, MA, 1988) |
| "After 4 or 13 weeks of IMA treatment, liver hypertrophy was observed at the tumor-inducible dose without differences among genotypes or durations." | 1.43 | A crucial role of constitutive androstane receptor (CAR) in liver tumor development by imazalil in mice. ( Inoue, K; Kodama, Y; Matsuo, S; Takahashi, M; Tamura, K; Yoshida, M, 2016) |
| " Three weeks after DEN treatment, Fas-mediated liver cell apoptosis induced by anti-Fas antibody resulted in a biphasic effect on induction of liver cell tumours, depending on dosage and time of antibody administration." | 1.31 | Effects of Fas-mediated liver cell apoptosis on diethylnitrosamine-induced hepatocarcinogenesis in mice. ( Hara, A; Kawabata, K; Matsunaga, K; Mori, H; Sugie, S; Yamada, Y; Yoshimi, N, 2000) |
| " These rats had been treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) under different dosing regimens, but we used the same administered biweekly dose of 1." | 1.31 | Hepatocarcinogenesis in female Sprague-Dawley rats following discontinuous treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin. ( Lucier, GW; Portier, CJ; Sills, RC; Tritscher, AM; Walker, NJ, 2000) |
| "Co-treatment of rotenone and WY-14,643 (group IV) decreased focal DNA synthesis and mitosis and increased the incidence of apoptotic hepatocytes." | 1.30 | Inhibition of WY-14,643 induced hepatic lesion growth in mice by rotenone. ( Ayoubi, SA; Isenberg, JS; Klaunig, JE; Kolaja, KL; Watkins, JB, 1997) |
| " The data indicate that at least in hepatocellular tumours of the C57Bl/10J strain and using chronic dosing regimes the ras genes do not represent markers for in vivo genotoxic activity." | 1.28 | Point mutation analysis of ras genes in spontaneous and chemically induced C57Bl/10J mouse liver tumours. ( Hardaker, KJ; Lord, PG; Loughlin, JM; Marsden, AM; Orton, TC, 1992) |
| "d-Limonene treatment alone caused a significant increase in the number of atypical tubules and atypical hyperplasias in F344 rats when compared with the F344 vehicle control." | 1.28 | The presence of alpha 2u-globulin is necessary for d-limonene promotion of male rat kidney tumors. ( Dietrich, DR; Swenberg, JA, 1991) |
| "Tracheal papillomas were not seen in untreated hamsters or in those not given NDEA and fed diets containing PBB." | 1.28 | Promoting effect of polybrominated biphenyls on tracheal papillomas in Syrian golden hamsters. ( Sleight, SD, 1989) |
| "Diethylnitrosamine (NDEA) was administered subcutaneously to non-icteric and icteric Gunn rats." | 1.27 | The influence of metabolic liver defects on diethylnitrosamine (NDEA)-carcinogenesis in Gunn rats. ( Althoff, J; Fehst, HJ; Mohr, U, 1985) |
| "The dose-response of diethylnitrosamine (DENA) initiation of hepatocarcinogenesis was determined in infant Balb/c male mice with and without subsequent phenobarbital treatment." | 1.27 | Dose-response relationship of diethylnitrosamine-initiated tumors in neonatal balb/c mice: effect of phenobarbital promotion. ( Klaunig, JE; Pereira, MA; Ruch, RJ; Weghorst, CM, 1988) |
| "induced tumors of liver (hepatocellular cancers and adenomas), and of hematopoietic system (hemocytoblastosis)." | 1.26 | The induction of tumors in Rana temporaria with nitrosamines. ( Khudoley, VV, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (40.74) | 18.7374 |
| 1990's | 32 (39.51) | 18.2507 |
| 2000's | 8 (9.88) | 29.6817 |
| 2010's | 8 (9.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Man, S | 1 |
| Li, J | 1 |
| Fan, W | 1 |
| Chai, H | 1 |
| Liu, Z | 1 |
| Gao, W | 1 |
| Shibata, Y | 1 |
| Hara, T | 1 |
| Nagano, J | 1 |
| Nakamura, N | 1 |
| Ohno, T | 2 |
| Ninomiya, S | 1 |
| Ito, H | 2 |
| Tanaka, T | 3 |
| Saito, K | 3 |
| Seishima, M | 1 |
| Shimizu, M | 2 |
| Moriwaki, H | 2 |
| Tsurumi, H | 1 |
| Kuwata, K | 1 |
| Inoue, K | 2 |
| Ichimura, R | 1 |
| Takahashi, M | 3 |
| Kodama, Y | 2 |
| Shibutani, M | 2 |
| Yoshida, M | 3 |
| Mercer, KE | 1 |
| Pulliam, C | 1 |
| Hennings, L | 1 |
| Lai, K | 1 |
| Cleves, M | 1 |
| Jones, E | 1 |
| Drake, RR | 1 |
| Ronis, M | 1 |
| Mitchell, J | 1 |
| Tinkey, PT | 1 |
| Avritscher, R | 1 |
| Van Pelt, C | 1 |
| Eskandari, G | 1 |
| Konnath George, S | 1 |
| Xiao, L | 1 |
| Cressman, E | 1 |
| Morris, JS | 1 |
| Rashid, A | 1 |
| Kaseb, AO | 1 |
| Amin, HM | 1 |
| Uthamanthil, R | 1 |
| Tamura, K | 1 |
| Matsuo, S | 1 |
| Iatropoulos, MJ | 1 |
| Cerven, DR | 1 |
| de George, G | 1 |
| von Keutz, E | 1 |
| Williams, GM | 3 |
| Kawai, M | 1 |
| Saegusa, Y | 1 |
| Kemmochi, S | 1 |
| Harada, T | 1 |
| Shimamoto, K | 1 |
| Mitsumori, K | 1 |
| Sakai, H | 1 |
| Shirakami, Y | 1 |
| Yasuda, Y | 1 |
| Kubota, M | 1 |
| Terakura, D | 1 |
| Baba, A | 1 |
| Hara, Y | 1 |
| Lahm, H | 1 |
| Gittner, K | 1 |
| Krebs, O | 1 |
| Sprague, L | 1 |
| Deml, E | 1 |
| Oesterle, D | 1 |
| Hoeflich, A | 1 |
| Wanke, R | 1 |
| Wolf, E | 1 |
| Rossmanith, W | 1 |
| Chabicovsky, M | 1 |
| Grasl-Kraupp, B | 1 |
| Peter, B | 1 |
| Schausberger, E | 1 |
| Schulte-Hermann, R | 1 |
| TAKAYAMA, S | 1 |
| OOTA, K | 1 |
| Sukata, T | 1 |
| Uwagawa, S | 1 |
| Ozaki, K | 1 |
| Sumida, K | 1 |
| Kikuchi, K | 1 |
| Kushida, M | 1 |
| Morimura, K | 1 |
| Oeda, K | 1 |
| Okuno, Y | 1 |
| Mikami, N | 1 |
| Fukushima, S | 1 |
| da Silva, TC | 1 |
| Paula da Silva, A | 1 |
| Akisue, G | 1 |
| Luis Avanzo, J | 1 |
| Kazumi Nagamine, M | 1 |
| Fukumasu, H | 1 |
| Matsuzaki, P | 1 |
| César Raspantini, P | 1 |
| Haraguchi, M | 1 |
| Lima Górniak, S | 1 |
| Dagli, ML | 1 |
| Yager, JD | 1 |
| Yager, R | 1 |
| Gurkalo, VK | 1 |
| Zabezhinskiĭ, MA | 1 |
| Diwan, BA | 6 |
| Rice, JM | 6 |
| Ward, JM | 7 |
| Ohshima, M | 2 |
| Lynch, PH | 1 |
| Creasia, D | 1 |
| Lynch, P | 1 |
| Riggs, C | 1 |
| Dalbey, WE | 1 |
| Preussmann, R | 1 |
| Habs, M | 1 |
| Habs, H | 1 |
| Schmähl, D | 1 |
| Vesselinovitch, SD | 1 |
| Iversen, OH | 1 |
| Okazaki, S | 1 |
| Hoshiya, T | 1 |
| Takahashi, S | 2 |
| Futakuchi, M | 1 |
| Hirose, M | 3 |
| Ledwith, BJ | 1 |
| Joslyn, DJ | 1 |
| Troilo, P | 1 |
| Leander, KR | 1 |
| Clair, JH | 1 |
| Soper, KA | 1 |
| Manam, S | 1 |
| Prahalada, S | 1 |
| van Zwieten, MJ | 1 |
| Nichols, WW | 1 |
| Tsuda, H | 5 |
| Matsumoto, K | 2 |
| Iwase, T | 2 |
| Nishida, Y | 2 |
| Baba, H | 1 |
| Gebhardt, R | 2 |
| Sirma, H | 1 |
| Stenbäck, F | 1 |
| Henneman, JR | 2 |
| Nims, RW | 2 |
| Pereira, MA | 4 |
| Yamada, Y | 4 |
| Takashi, M | 1 |
| Sakata, T | 1 |
| Nakano, Y | 1 |
| Takagi, Y | 1 |
| Hibi, H | 1 |
| Miyake, K | 1 |
| Cao, J | 1 |
| Xu, Y | 1 |
| Chen, J | 1 |
| Klaunig, JE | 7 |
| Kimura, J | 2 |
| Ogiso, T | 1 |
| Yoshida, Y | 1 |
| Akagi, K | 1 |
| Hasegawa, R | 2 |
| Kurata, M | 1 |
| Shirai, T | 2 |
| Steinmetz, KL | 1 |
| Omori, Y | 1 |
| Krutovskikh, V | 1 |
| Mironov, N | 1 |
| Yamasaki, H | 1 |
| Pascale, RM | 1 |
| De Miglio, MR | 1 |
| Muroni, MR | 1 |
| Simile, MM | 1 |
| Daino, L | 1 |
| Seddaiu, MA | 1 |
| Nufris, A | 1 |
| Gaspa, L | 1 |
| Deiana, L | 1 |
| Feo, F | 1 |
| Kim, DJ | 1 |
| Han, BS | 1 |
| Ahn, B | 1 |
| Ito, N | 2 |
| Lapis, K | 1 |
| Bocsi, J | 1 |
| Timar, F | 1 |
| Lapis, P | 1 |
| Thorgeirsson, UP | 1 |
| Isenberg, JS | 1 |
| Kolaja, KL | 1 |
| Ayoubi, SA | 1 |
| Watkins, JB | 1 |
| Lee, GH | 1 |
| Ooasa, T | 1 |
| Osanai, M | 1 |
| Ookawa, K | 1 |
| Nakano, H | 1 |
| Kakizaki, I | 1 |
| Hatayama, I | 1 |
| Kajihara-Kano, H | 1 |
| Hayakari, M | 1 |
| Takahata, T | 1 |
| Satoh, K | 2 |
| Tsuchida, S | 2 |
| Shiota, G | 1 |
| Harada, K | 1 |
| Ishida, M | 1 |
| Tomie, Y | 1 |
| Okubo, M | 1 |
| Katayama, S | 1 |
| Kawasaki, H | 1 |
| Ogawa, K | 1 |
| Kishibe, K | 1 |
| Ishizaki, K | 1 |
| Tokusashi, Y | 1 |
| Miyajima, K | 1 |
| Shiraki, K | 1 |
| Ando, J | 1 |
| Kudoh, K | 1 |
| Nakae, D | 1 |
| Maekawa, A | 1 |
| Yoshimi, N | 2 |
| Sugie, S | 2 |
| Suzui, M | 1 |
| Matsunaga, K | 2 |
| Kawabata, K | 2 |
| Hara, A | 2 |
| Mori, H | 2 |
| Anderson, SP | 1 |
| Cattley, RC | 1 |
| Corton, JC | 1 |
| Walker, NJ | 1 |
| Tritscher, AM | 1 |
| Sills, RC | 1 |
| Lucier, GW | 1 |
| Portier, CJ | 1 |
| Furukawa, F | 1 |
| Nishikawa, A | 1 |
| Miyauchi, M | 1 |
| Nakamura, H | 1 |
| Son, HY | 1 |
| Yamagishi, M | 1 |
| Matsushima, T | 1 |
| Sugimura, T | 1 |
| Thust, R | 2 |
| Warzok, R | 1 |
| Khudoley, VV | 1 |
| Feron, VJ | 2 |
| Kruysse, A | 1 |
| Worzok, R | 1 |
| Spit, BJ | 1 |
| Lee, YS | 1 |
| Seo, JS | 1 |
| Chung, HT | 1 |
| Cho, KJ | 1 |
| Jan, JJ | 1 |
| Ito, M | 1 |
| Oyama, F | 1 |
| Titani, K | 1 |
| Ushijima, T | 1 |
| Nagao, M | 1 |
| Hirono, I | 1 |
| Lord, PG | 1 |
| Hardaker, KJ | 1 |
| Loughlin, JM | 1 |
| Marsden, AM | 1 |
| Orton, TC | 1 |
| Lijinsky, W | 1 |
| Kovatch, RM | 2 |
| Thomas, BJ | 1 |
| Dietrich, DR | 1 |
| Swenberg, JA | 1 |
| Gunning, WT | 1 |
| Castonguay, A | 1 |
| Goldblatt, PJ | 1 |
| Stoner, GD | 1 |
| Lagopoulos, L | 1 |
| Sunahara, GI | 1 |
| Würzner, H | 1 |
| Dombrowsky, I | 1 |
| Stalder, R | 1 |
| Sell, S | 1 |
| Hunt, JM | 1 |
| Dunsford, HA | 1 |
| Chisari, FV | 1 |
| Cortinovis, C | 1 |
| Klimek, F | 1 |
| Nogueira, E | 1 |
| Thiyagarajah, A | 1 |
| Grizzle, JM | 1 |
| Rijhsinghani, KS | 1 |
| Abrahams, C | 1 |
| Swerdlow, MA | 1 |
| Ghose, T | 1 |
| Sleight, SD | 1 |
| Huntrakoon, M | 1 |
| Menon, CD | 1 |
| Hung, KS | 1 |
| Lubet, RA | 1 |
| Weghorst, CM | 3 |
| Moore, MA | 1 |
| Asamoto, M | 1 |
| Sato, K | 1 |
| Ichihara, A | 1 |
| Althoff, J | 1 |
| Fehst, HJ | 1 |
| Mohr, U | 1 |
| Hagiwara, A | 1 |
| Ruch, RJ | 2 |
| Herren-Freund, SL | 1 |
| Dragani, TA | 2 |
| Manenti, G | 2 |
| Della Porta, G | 2 |
| Du, ZM | 1 |
| Hu, H | 1 |
| Schuller, HM | 1 |
| Singh, G | 1 |
| Katyal, SL | 1 |
| Anderson, LM | 1 |
| Yamamoto, A | 1 |
| Hisanaga, A | 1 |
| Ishinishi, N | 1 |
| Galliani, G | 1 |
2 reviews available for diethylnitrosamine and Adenoma, Basal Cell
| Article | Year |
|---|---|
Experimental carcinogenesis in small aquarium fishes.
Topics: 2-Acetylaminofluorene; Adenoma; Adenoma, Bile Duct; Aflatoxins; Animals; Benzopyrenes; Carcinogens; | 1976 |
Strain-dependent effects of phenobarbital on liver tumor promotion in inbred mice.
Topics: Adenoma; Animals; Biotransformation; Cocarcinogenesis; Diethylnitrosamine; Disease Susceptibility; F | 1990 |
79 other studies available for diethylnitrosamine and Adenoma, Basal Cell
| Article | Year |
|---|---|
Inhibition of pulmonary adenoma in diethylnitrosamine-induced rats by Rhizoma paridis saponins.
Topics: Adenoma; Animals; Carcinogens; Diethylnitrosamine; Lung Neoplasms; Magnoliopsida; Male; Metabolomics | 2015 |
The Role of Indoleamine 2,3-Dioxygenase in Diethylnitrosamine-Induced Liver Carcinogenesis.
Topics: Adenoma; Animals; CD8 Antigens; Cyclooxygenase 2; Diethylnitrosamine; Disease Progression; Forkhead | 2016 |
Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development.
Topics: Adenoma; Animals; Aryl Hydrocarbon Hydroxylases; Cell Proliferation; Cell Transformation, Neoplastic | 2016 |
Soy Protein Isolate Protects Against Ethanol-Mediated Tumor Progression in Diethylnitrosamine-Treated Male Mice.
Topics: Adenoma; Alkylating Agents; Animals; Blotting, Western; Carcinoma, Hepatocellular; Diet; Diethylnitr | 2016 |
Validation of a Preclinical Model of Diethylnitrosamine-Induced Hepatic Neoplasia in Yucatan Miniature Pigs.
Topics: Adenoma; alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Models, | 2016 |
A crucial role of constitutive androstane receptor (CAR) in liver tumor development by imazalil in mice.
Topics: Adenoma; Animals; Aryl Hydrocarbon Hydroxylases; Cell Proliferation; Cocarcinogenesis; Constitutive | 2016 |
Reduction by dietary matrix metalloproteinase inhibitor BAY 12-9566N of neoplastic development induced by diethylnitrosamine, N-nitrosodimethylamine, or 7,12-dimethylbenz(a)anthracene in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Antineoplastic Agents; Biphenyl Compounds; Carci | 2008 |
Cytokeratin 8/18 is a useful immunohistochemical marker for hepatocellular proliferative lesions in mice.
Topics: Adenoma; Animals; Biomarkers; Carcinoma; Carcinoma, Hepatocellular; Diethylnitrosamine; Hepatectomy; | 2010 |
Preventive effects of (-)-epigallocatechin gallate on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db Mice.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Diabetes Mellitus, Experimental; D | 2011 |
Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice.
Topics: Adenoma; Alkylating Agents; Animals; Diethylnitrosamine; Dose-Response Relationship, Drug; Gene Expr | 2002 |
Follistatin overexpression in rodent liver tumors: a possible mechanism to overcome activin growth control.
Topics: Activins; Adenoma; Alternative Splicing; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell | 2002 |
INDUCTION OF MALIGNANT TUMORS IN VARIOUS STRAINS OF MICE BY ORAL ADMINISTRATION OF N-NITROSODIMETHYLAMINE AND N-NITROSODIETHYLAMINE.
Topics: Adenocarcinoma; Adenoma; Administration, Oral; Animals; Carcinogens; Diethylnitrosamine; Dimethylnit | 1965 |
alpha(2)-Macroglobulin: a novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers.
Topics: Adenoma; Alkylating Agents; alpha-Macroglobulins; Animals; Anticholesteremic Agents; Biomarkers, Tum | 2004 |
Inhibitory effects of Pfaffia paniculata (Brazilian ginseng) on preneoplastic and neoplastic lesions in a mouse hepatocarcinogenesis model.
Topics: Adenoma; Alkylating Agents; Amaranthaceae; Animals; Diethylnitrosamine; Disease Models, Animal; Fema | 2005 |
Oral contraceptive steroids as promoters of hepatocarcinogenesis in female Sprague-Dawley rats.
Topics: Adenoma; Animals; Body Weight; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Diet; Diethyln | 1980 |
[Effects of apomorphine and haloperidol on experimental hepatocarcinogenesis].
Topics: Adenoma; Adenoma, Bile Duct; Animals; Apomorphine; Cell Transformation, Neoplastic; Diethylnitrosami | 1983 |
Inhibition by phenobarbital and lack of effect of amobarbital on the development of liver tumors induced by N-nitrosodiethylamine in juvenile B6C3F1 mice.
Topics: Adenocarcinoma; Adenoma; Amobarbital; Animals; Body Weight; Diethylnitrosamine; Liver Neoplasms, Exp | 1984 |
Dissimilar patterns of promotion by di(2-ethylhexyl)phthalate and phenobarbital of hepatocellular neoplasia initiated by diethylnitrosamine in B6C3F1 mice.
Topics: Adenoma; Animals; Carcinogens; Diethylhexyl Phthalate; Diethylnitrosamine; Drug Synergism; Hyperplas | 1983 |
Formaldehyde and tumors in hamster respiratory tract.
Topics: Adenoma; Aging; Animals; Carcinogens; Cricetinae; Diethylnitrosamine; Formaldehyde; Male; Mesocricet | 1982 |
Carcinogenicity of N-nitrosodiethanolamine in rats at five different dose levels.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, Drug; | 1982 |
Infant mouse as a sensitive bioassay system for carcinogenicity of N-nitroso compounds.
Topics: Adenoma; Aging; Animals; Animals, Newborn; Biological Assay; Diethylnitrosamine; Dose-Response Relat | 1980 |
Tumorigenicity of N-nitroso-diaethyl, -dimethyl and -diphenyl-amines in skin painting experiments. A study utilizing the tetrazolium test and skin applications on hairless mice.
Topics: Adenoma; Animals; Diethylnitrosamine; Dimethylnitrosamine; Female; Lung Neoplasms; Male; Mice; Neopl | 1980 |
Modification of hepato- and renal carcinogenesis by catechol and its isomers in rats pretreated with N-ethyl-N-hydroxyethylnitrosamine.
Topics: Adenoma; Administration, Oral; Alpha-Globulins; Animals; Body Weight; Carcinoma, Renal Cell; Catecho | 1993 |
Induction of minisatellite DNA rearrangements by genotoxic carcinogens in mouse liver tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinogens; Carcinoma; Diethylnitrosamine; DNA | 1995 |
Enhanced neoplastic lesion development with adenine-induced experimental multicystic nephropathy by adenine--a model system for the analysis of renal tumor generation in long-term hemodialysis patients.
Topics: Adenine; Adenoma; Animals; Diethylnitrosamine; Epithelium; Hyperplasia; Kidney Diseases; Kidney Neop | 1994 |
Non-linearity of neoplastic conversion induced in rat liver by low exposures to diethylnitrosamine.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Dose-Response Relationship, Drug; D | 1993 |
Tumor promotion by an anticonvulsant agent, phenytoin, in mouse liver: correlation with CYP2B induction.
Topics: Adenoma; Animals; Body Weight; Carcinogens; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; | 1993 |
Comparison in C3H and C3B6F1 mice of the sensitivity to diethylnitrosamine-initiation and phenobarbital-promotion to the extent of cell proliferation.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Cell Division; Diethylnitrosamine; Female; Liver; Liver | 1993 |
Strain and sex differences in kidney carcinogenesis in rats treated with N-ethyl-N-hydroxyethylnitrosamine and uracil.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Diethylnitrosamine; Female; Kidney Neoplasms; Male; R | 1995 |
Chemopreventive effects of green and black tea on pulmonary and hepatic carcinogenesis.
Topics: Adenoma; Administration, Oral; Analysis of Variance; Animals; Carcinogens; Diethylnitrosamine; Disea | 1996 |
Lack of chemoprevention effects of the monoterpene d-limonene in a rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carc | 1996 |
Transforming growth factor-alpha in carcinogen-induced F344 rat hepatic foci.
Topics: Adenoma; Animals; Carcinoma; Coloring Agents; Diethylnitrosamine; DNA; Glutathione Transferase; Immu | 1996 |
Cx32 gene mutation in a chemically induced rat liver tumour.
Topics: Adenoma; Animals; Carcinogens; Connexins; Diethylnitrosamine; Exons; Gap Junction beta-1 Protein; He | 1996 |
c-myc amplification in pre-malignant and malignant lesions induced in rat liver by the resistant hepatocyte model.
Topics: Adenoma; Animals; Blotting, Northern; Blotting, Southern; Carcinoma, Hepatocellular; Deoxyribonuclea | 1996 |
Enhancement by indole-3-carbinol of liver and thyroid gland neoplastic development in a rat medium-term multiorgan carcinogenesis model.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Dieth | 1997 |
Studies on the proliferative activity of diethylnitrosamine-induced hepatocellular carcinomas in monkeys.
Topics: Adenoma; Animals; Carcinogens; Cell Division; Chlorocebus aethiops; Diagnosis, Differential; Diethyl | 1997 |
Inhibition of WY-14,643 induced hepatic lesion growth in mice by rotenone.
Topics: Adenoma; Animals; Apoptosis; Body Weight; Bromodeoxyuridine; Carcinogens; Diethylnitrosamine; DNA; L | 1997 |
Mechanism of the paradoxical, inhibitory effect of phenobarbital on hepatocarcinogenesis initiated in infant B6C3F1 mice with diethylnitrosamine.
Topics: Adenoma; Animals; Animals, Newborn; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Cell Divi | 1998 |
Identification of glutathione S-transferase p-1 as the class pi form dominantly expressed in mouse hepatic adenomas.
Topics: Adenoma; Animals; Diethylnitrosamine; Escherichia coli; Female; Glutathione Transferase; Liver Neopl | 1998 |
Inhibition of hepatocellular carcinoma by glycyrrhizin in diethylnitrosamine-treated mice.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Diethylnitrosamine; Disease Models, Animal; | 1999 |
Beta-catenin mutations are frequent in hepatocellular carcinomas but absent in adenomas induced by diethylnitrosamine in B6C3F1 mice.
Topics: Adenoma; Animals; beta Catenin; Carcinoma, Hepatocellular; Cytoskeletal Proteins; Diethylnitrosamine | 1999 |
Hepatotoxicity and consequently increased cell proliferation are associated with flumequine hepatocarcinogenesis in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenoma; Animals; Anti-Infective Agents; Carcinogenicity Tests; Cell Di | 1999 |
Beta-catenin (Ctnnb1) gene mutations in diethylnitrosamine (DEN)-induced liver tumors in male F344 rats.
Topics: Adenoma; Amino Acid Substitution; Animals; beta Catenin; Binding Sites; Carcinogenicity Tests; Carci | 1999 |
Hepatic expression of acute-phase protein genes during carcinogenesis induced by peroxisome proliferators.
Topics: Adenoma; Animals; Diethylhexyl Phthalate; Diethylnitrosamine; Gene Expression Regulation, Neoplastic | 1999 |
Effects of Fas-mediated liver cell apoptosis on diethylnitrosamine-induced hepatocarcinogenesis in mice.
Topics: Adenoma; Alkylating Agents; Animals; Antibodies, Monoclonal; Apoptosis; Cell Transformation, Neoplas | 2000 |
Hepatocarcinogenesis in female Sprague-Dawley rats following discontinuous treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Diethylnitrosamine; Drug Administration Schedule; Female; | 2000 |
Concurrent administration of fish meal and sodium nitrite does not promote renal carcinogenesis in rats after initiation with N-ethyl-N-hydroxyethylnitrosamine.
Topics: Adenocarcinoma; Adenoma; Adrenal Glands; Animals; Body Weight; Cocarcinogenesis; Diet; Diethylnitros | 2000 |
[Transplacental carcinogenic action of diethylnitrosamine in the Dzungarian hamster (author's transl)].
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Cricetinae; Cystadenoma; Diethylnitrosamine; | 1977 |
The induction of tumors in Rana temporaria with nitrosamines.
Topics: Adenoma; Animals; Anura; Carcinoma, Hepatocellular; Diethylnitrosamine; Dimethylnitrosamine; Hematop | 1977 |
Effects of exposure to furfural vapour in hamsters simultaneously treated with benzo[alpha] pyrene or diethylnitrosamine.
Topics: Adenoma; Animals; Benzopyrenes; Body Weight; Carcinoma; Cocarcinogenesis; Cricetinae; Diethylnitrosa | 1978 |
Morphology of diethylnitrosamine-induced lung tumours in Dzungarian dwarf hamsters.
Topics: Adenocarcinoma; Adenoma; Animals; Cricetinae; Diethylnitrosamine; Lung Neoplasms; Neoplasms, Experim | 1977 |
Comparative study of the ultrastructure of Tracheal and pulmonary tumours induced by multiple intratracheal instillations of diethylnitrosamine in Syrian golden hamsters.
Topics: Adenoma; Animals; Cell Membrane; Cell Nucleus; Cilia; Cricetinae; Diethylnitrosamine; Epithelial Cel | 1975 |
Lung adenoma development and NK activity in mice treated with multiple carcinogens.
Topics: Adenoma; Animals; Diethylnitrosamine; Female; Killer Cells, Natural; Lung Neoplasms; Methylnitrosour | 1992 |
Absence of ras family point mutations at codons 12, 13 and 61 in N-ethyl-N-hydroxyethylnitrosamine- or N-nitrosomorpholine-induced renal cell tumors in rats.
Topics: Adenoma; Animals; Base Sequence; Carcinogens; Carcinoma, Renal Cell; Diethylnitrosamine; Exons; Gene | 1992 |
Point mutation analysis of ras genes in spontaneous and chemically induced C57Bl/10J mouse liver tumours.
Topics: 2-Acetylaminofluorene; Adenoma; Aminobiphenyl Compounds; Animals; Base Sequence; Carcinoma; Diethyln | 1992 |
The carcinogenic effect of methapyrilene combined with nitrosodiethylamine given to rats in low doses.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Diethylnitrosamine; Drug Interactions; Female; Hepatectomy | 1992 |
The presence of alpha 2u-globulin is necessary for d-limonene promotion of male rat kidney tumors.
Topics: Adenoma; Alpha-Globulins; Animals; Body Weight; Carcinogens; Cell Division; Cyclohexenes; Diethylnit | 1991 |
Strain A/J mouse lung adenoma growth patterns vary when induced by different carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenoma; Aflatoxins; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformatio | 1991 |
The effects of alternating dietary restriction and ad libitum feeding of mice on the development of diethylnitrosamine-induced liver tumours and its correlation to insulinaemia.
Topics: Adenoma; Animals; Body Weight; Carcinoma, Hepatocellular; Diet; Diethylnitrosamine; Eating; Female; | 1991 |
Synergy between hepatitis B virus expression and chemical hepatocarcinogens in transgenic mice.
Topics: Adenoma; Aflatoxins; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Female; Gene Expression | 1991 |
Rat hepatocarcinogenesis induced by N-nitrosodiethylamine and N-nitrosomorpholine continuously administered at low doses. From basophilic areas of hepatocytes to hepatocellular tumors.
Topics: Adenoma; Administration, Oral; Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, | 1991 |
Diethylnitrosamine-induced pancreatic neoplasms in the fish Rivulus ocellatus marmoratus.
Topics: Adenocarcinoma; Adenoma; Animals; Cystadenoma; Diethylnitrosamine; Dose-Response Relationship, Drug; | 1986 |
Crystalline inclusions associated with lung adenomas in C57BLxC3H F1 mice.
Topics: Adenoma; alpha 1-Antitrypsin; Animals; Crosses, Genetic; Diethylnitrosamine; Immunoglobulin A; Immun | 1988 |
Promoting effect of polybrominated biphenyls on tracheal papillomas in Syrian golden hamsters.
Topics: Adenoma; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Cricetinae; Diet; Diethylnitrosamine; | 1989 |
Glutamine synthetase heterogeneous expression as a marker for the cellular lineage of preneoplastic and neoplastic liver populations.
Topics: 2-Acetylaminofluorene; Adenoma; Aflatoxin B1; Aflatoxins; Animals; Biomarkers, Tumor; Diethylnitrosa | 1989 |
Diethylnitrosamine-induced pulmonary endocrine cell hyperplasia and its association with adenomatosis and adenocarcinoma in rabbits.
Topics: Adenocarcinoma; Adenoma; Animals; Diethylnitrosamine; Endocrine Glands; Hyperplasia; Lung; Lung Neop | 1989 |
Lack of promoting effect of clonazepam on the development of N-nitrosodiethylamine-initiated hepatocellular tumors in mice is correlated with its inability to inhibit cell-to-cell communication in mouse hepatocytes.
Topics: Adenoma; Aminopyrine N-Demethylase; Animals; Carcinogens; Carcinoma; Cell Communication; Clonazepam; | 1989 |
Comparison of the various forms of glutathione S-transferase with glucose-6-phosphate dehydrogenase and gamma-glutamyltranspeptidase as markers of preneoplastic and neoplastic lesions in rat kidney induced by N-ethyl-N-hydroxyethylnitrosamine.
Topics: Adenoma; Animals; Carcinogens; Diethylnitrosamine; gamma-Glutamyltransferase; Glucosephosphate Dehyd | 1985 |
The influence of metabolic liver defects on diethylnitrosamine (NDEA)-carcinogenesis in Gunn rats.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Female; Hemangioendothelioma; Heman | 1985 |
Modifying effects of butylated hydroxyanisole, di(2-ethylhexyl)phthalate or indomethacin on mouse hepatocarcinogenesis initiated by N-nitrosodiethylamine.
Topics: Adenoma; Animals; Butylated Hydroxyanisole; Cocarcinogenesis; Diethylhexyl Phthalate; Diethylnitrosa | 1986 |
Dose-response relationship of diethylnitrosamine-initiated tumors in neonatal balb/c mice: effect of phenobarbital promotion.
Topics: Adenoma; Animals; Animals, Newborn; Cocarcinogenesis; Diethylnitrosamine; Dose-Response Relationship | 1988 |
Effect of phenobarbital on the development of liver tumors in juvenile and adult mice.
Topics: Adenoma; Age Factors; Animals; Carcinoma; Diethylnitrosamine; DNA; Liver Neoplasms, Experimental; Ma | 1986 |
Genetic susceptibility to murine hepatocarcinogenesis is associated with high growth rate of NDEA-initiated hepatocytes.
Topics: Adenoma; Animals; Carcinoma; Diethylnitrosamine; Female; Liver Neoplasms, Experimental; Male; Mice; | 1987 |
Effect of the age of B6C3F1 mice on phenobarbital promotion of diethylnitrosamine-initiated liver tumors.
Topics: Adenoma; Aging; Animals; Cocarcinogenesis; Diethylnitrosamine; Liver Neoplasms; Male; Mice; Mice, In | 1987 |
[Pulmonary tumors induced by diethylnitrosamine in mice].
Topics: Adenoma; Animals; Diethylnitrosamine; Lung Neoplasms; Male; Mice | 1987 |
Tumor-initiating and promoting activities of di(2-ethylhexyl) phthalate in vivo and in vitro.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; Diethylh | 1986 |
Immunocytochemical localization of the surfactant apoprotein and Clara cell antigen in chemically induced and naturally occurring pulmonary neoplasms of mice.
Topics: Adenoma; Animals; Antigens; Apoproteins; Carcinoma; Diethylnitrosamine; Female; Hyperplasia; Immunoe | 1985 |
Comparative study on the carcinogenicity of N-nitrosodiethylamine and benzo[a]pyrene to the lung of Syrian golden hamsters induced by intermittent instillations to the trachea.
Topics: Adenoma; Administration, Topical; Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cricetinae; Die | 1985 |
Promoting effects of 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene in mouse hepatocarcinogenesis.
Topics: Adenoma; Animals; Cocarcinogenesis; Diethylnitrosamine; DNA; Female; Liver Neoplasms, Experimental; | 1985 |