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diethylhexyl phthalate and Disease Models, Animal

diethylhexyl phthalate has been researched along with Disease Models, Animal in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.69)18.2507
2000's4 (15.38)29.6817
2010's12 (46.15)24.3611
2020's8 (30.77)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Chan, MWY; Hung, CH; Kuo, FC; Li, SS; Suen, JL; Tsai, ML; Wang, SL; Wu, CF; Wu, MT; Wu, ST1
Chen, G; Han, Y; Hu, M; Lu, Y; Pang, X; Qu, J; Wang, X1
Huang, F; Li, D; Liu, X; Liu, Y; Long, C; Shen, L; Wei, G; Zhou, Y1
Annunziato, K; Boisvert, JD; Bowsher, AM; Jacobs, HM; Moreau, HM; Nguyen, M; Pantazis, J; Sant, KE; Smolowitz, RM; Timme-Laragy, A; Williams, LM1
Ma, K; Na, X; Wu, H1
Hong, SL; Kang, HY; Ke, X; Li, J; Shen, Y; Wang, XQ; Zou, QY1
Ahmad, SF; Al-Harbi, NO; Albekairi, TH; Ali, N; Alsaleh, NB; Alsanea, S; Attia, SM; Bakheet, SA; Nadeem, A1
Ahmad, SF; Al-Harbi, NO; Alfardan, AS; Alhazzani, K; Alhoshani, A; Alsanea, S; Attia, SM; Bakheet, SA; Mahmood, HM; Nadeem, A1
Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Alfardan, AS; AlSharari, SD; Nadeem, A1
Chen, H; Han, X; Song, X; Xu, Q; Ye, L; Zhao, T; Zhao, Y; Zhou, L1
Cheong, JH; Cho, SC; Han, DH; Kim, BN; Kim, JW; Park, S; Shin, MS; Yoo, HJ1
Chen, S; Li, B; Li, R; Mao, L; Yang, X; You, H; Yuan, Y1
Chen, G; Han, Y; Hu, P; Liu, X; Miao, J; Wang, X; Xu, G; Zhang, Y; Zhu, C; Zhu, W1
Hsiao, SH; Hsu, MH; Kou, YR; Lee, TS; Pao, KC; Shyue, SK; Zhao, JF1
D'Hanis, W; Janitzky, K; Kröber, A; Schwegler, H1
Nuttall, JR1
Chen, S; Li, R; Mao, L; Wei, C; Yang, X; You, H; Zhang, Z1
Adams, R; Gennings, C; Kita, DH; Machado, DL; Martino-Andrade, AJ; Meyer, KB; Morais, RN; Swan, SH; Venturelli, AC1
Cho, WS; Choi, M; Han, BS; Jeong, J; Park, SN; Son, WC1
Davis, BJ; Lovekamp-Swan, T1
Brunet, C; Dine, T; Dupin-Spriet, T; Gressier, B; Kambia, K; Luyckx, M1
Clausen, PA; Hansen, EW; Hansen, JS; Larsen, ST; Nielsen, GD1
Devor, DE; Henneman, JR; Ward, JM; Weghorst, CM1
Becedas, L; Bengtsson Ahlberg, M; Georgellis, A; Lundqvist, G; Mehrotra, K; Morgenstern, R1

Reviews

3 review(s) available for diethylhexyl phthalate and Disease Models, Animal

ArticleYear
The plausibility of maternal toxicant exposure and nutritional status as contributing factors to the risk of autism spectrum disorders.
    Nutritional neuroscience, 2017, Volume: 20, Issue:4

    Topics: Animals; Autism Spectrum Disorder; Benzhydryl Compounds; Brain; Diethylhexyl Phthalate; Disease Models, Animal; Ethanol; Female; Fetal Development; Homeostasis; Humans; Inflammation; Maternal Exposure; Metals, Heavy; Micronutrients; Nutritional Status; Obesity; Phenols; Pregnancy; Risk Factors; Valproic Acid

2017
Mechanisms of phthalate ester toxicity in the female reproductive system.
    Environmental health perspectives, 2003, Volume: 111, Issue:2

    Topics: Animals; Cyclic AMP; Diethylhexyl Phthalate; Disease Models, Animal; Esters; Estradiol; Estrus; Female; Granulosa Cells; Humans; Ovary; Ovulation; Phthalic Acids; Rats

2003
Di(2-ethylhexyl) phthalate.
    IARC monographs on the evaluation of carcinogenic risks to humans, 2000, Volume: 77

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Cricetinae; Diethylhexyl Phthalate; Disease Models, Animal; Environmental Exposure; Humans; Maximum Allowable Concentration; Mice; Neoplasms; Rats; Reproduction

2000

Other Studies

23 other study(ies) available for diethylhexyl phthalate and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Maternal di-(2-ethylhexyl) phthalate exposure elicits offspring IFN-λ upregulation: Insights from birth cohort, murine model, and in vitro mechanistic analysis.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 179

    Topics: Animals; Birth Cohort; Cohort Studies; Cytokines; Diethylhexyl Phthalate; Disease Models, Animal; Female; Humans; Infant; Interferon Lambda; Maternal Exposure; Mice; Pregnancy; Up-Regulation

2023
Di-(2-ethylhexyl)-phthalate interferes with T-follicular helper cell differentiation and cytokine secretion through signaling lymphocytic activation molecule family member-1.
    Journal of immunotoxicology, 2019, Volume: 16, Issue:1

    Topics: Administration, Oral; Anaphylaxis; Animals; Animals, Newborn; Cell Differentiation; Child; Diethylhexyl Phthalate; Disease Models, Animal; Humans; Interleukin-4; Interleukins; Lymph Nodes; Mice; Ovalbumin; Plasticizers; Signal Transduction; Signaling Lymphocytic Activation Molecule Associated Protein; Signaling Lymphocytic Activation Molecule Family Member 1; T-Lymphocytes, Helper-Inducer; Weaning

2019
TGF-β1 relieves epithelial-mesenchymal transition reduction in hypospadias induced by DEHP in rats.
    Pediatric research, 2020, Volume: 87, Issue:4

    Topics: Animals; Diethylhexyl Phthalate; Disease Models, Animal; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Developmental; Gestational Age; Hypospadias; Male; Penis; Rats, Sprague-Dawley; Signal Transduction; Smad2 Protein; Smad3 Protein; Tissue Culture Techniques; Transforming Growth Factor beta1; Urethra

2020
Embryonic exposures to mono-2-ethylhexyl phthalate induce larval steatosis in zebrafish independent of Nrf2a signaling.
    Journal of developmental origins of health and disease, 2021, Volume: 12, Issue:1

    Topics: Animals; Animals, Genetically Modified; Diethylhexyl Phthalate; Disease Models, Animal; Fatty Acid-Binding Proteins; Fatty Liver; Female; Gene Expression Regulation, Developmental; Humans; Larva; Lipid Metabolism; Loss of Function Mutation; Maternal Exposure; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction; Zebrafish Proteins

2021
Rosmarinic acid alleviates di-2-ethylhexyl phthalate (DEHP) -induced thyroid dysfunction via multiple inflammasomes activation.
    The Journal of toxicological sciences, 2020, Volume: 45, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Boraginaceae; Cell Death; Cells, Cultured; Cinnamates; Cytokines; Depsides; Diethylhexyl Phthalate; Disease Models, Animal; Dose-Response Relationship, Drug; Endocrine Disruptors; Hypothyroidism; Inflammasomes; Inflammation Mediators; Male; Phytotherapy; Rats, Sprague-Dawley; Rosmarinic Acid; Thyroid Epithelial Cells

2020
Effect of di-(2-ethylhexyl) phthalate (DEHP) on allergic rhinitis.
    Scientific reports, 2020, 09-03, Volume: 10, Issue:1

    Topics: Animals; Cytochrome P-450 CYP1A1; Diethylhexyl Phthalate; Disease Models, Animal; Environmental Exposure; Environmental Pollutants; Inflammation; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Oxidative Stress; Rhinitis, Allergic

2020
Aggravation of autism-like behavior in BTBR T+tf/J mice by environmental pollutant, di-(2-ethylhexyl) phthalate: Role of nuclear factor erythroid 2-related factor 2 and oxidative enzymes in innate immune cells and cerebellum.
    International immunopharmacology, 2021, Volume: 91

    Topics: Animals; Antioxidants; Autistic Disorder; Behavior, Animal; Cerebellum; Diethylhexyl Phthalate; Disease Models, Animal; Environmental Pollutants; Grooming; Immunity, Innate; Male; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Plasticizers; Social Behavior

2021
Exposure to the plasticizer, Di-(2-ethylhexyl) phthalate during juvenile period exacerbates autism-like behavior in adult BTBR T + tf/J mice due to DNA hypomethylation and enhanced inflammation in brain and systemic immune cells.
    Progress in neuro-psychopharmacology & biological psychiatry, 2021, 07-13, Volume: 109

    Topics: Animals; Autistic Disorder; Behavior, Animal; Brain; Cytokines; Diethylhexyl Phthalate; Disease Models, Animal; DNA Methylation; Inflammation; Mice; Plasticizers; Social Behavior

2021
Plasticizer, di(2-ethylhexyl)phthalate (DEHP) enhances cockroach allergen extract-driven airway inflammation by enhancing pulmonary Th2 as well as Th17 immune responses in mice.
    Environmental research, 2018, Volume: 164

    Topics: Allergens; Animals; Cockroaches; Cytokines; Diethylhexyl Phthalate; Disease Models, Animal; Humans; Inflammation; Mice; Mice, Inbred BALB C; Plasticizers; Respiratory System

2018
The effect of di-2-ethylhexyl phthalate on inflammation and lipid metabolic disorder in rats.
    Ecotoxicology and environmental safety, 2019, Apr-15, Volume: 170

    Topics: Adipocytes; Adiponectin; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Body Weight; CCAAT-Enhancer-Binding Protein-beta; Cholesterol; Diethylhexyl Phthalate; Disease Models, Animal; Female; Inflammation; Interleukin-1beta; Leptin; Lipid Metabolism; Male; Metabolic Diseases; Rats; Rats, Wistar; Triglycerides; Tumor Necrosis Factor-alpha

2019
Di-(2-ethylhexyl) phthalate exposure is negatively correlated with trait anxiety in girls but not with trait anxiety in boys or anxiety-like behavior in male mice.
    Journal of child neurology, 2015, Volume: 30, Issue:1

    Topics: Animals; Anxiety; Child; Cross-Sectional Studies; Diethylhexyl Phthalate; Disease Models, Animal; Exploratory Behavior; Female; Humans; Male; Mice; Plasticizers; Psychiatric Status Rating Scales; Sex Characteristics

2015
The adjuvant effect induced by di-(2-ethylhexyl) phthalate (DEHP) is mediated through oxidative stress in a mouse model of asthma.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 71

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Diethylhexyl Phthalate; Disease Models, Animal; Eosinophils; Glutathione; Immunoglobulin E; Lung; Male; Mice; Mice, Inbred BALB C; Neutrophils; Oxidative Stress; Reactive Oxygen Species

2014
Di-(2-ethylhexyl) phthalate adjuvantly induces imbalanced humoral immunity in ovalbumin-sensitized BALB/c mice ascribing to T follicular helper cells hyperfunction.
    Toxicology, 2014, Oct-03, Volume: 324

    Topics: Administration, Oral; Adoptive Transfer; Animals; B-Lymphocytes; Cell Proliferation; Diethylhexyl Phthalate; Disease Models, Animal; DNA-Binding Proteins; Environmental Pollutants; Germinal Center; Hypersensitivity; Immunity, Humoral; Immunoglobulin E; Immunoglobulin G; Interleukin-4; Interleukins; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Ovalbumin; Proto-Oncogene Proteins c-bcl-6; Proto-Oncogene Proteins c-maf; Risk Assessment; Risk Factors; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer

2014
Di-(2-ethylhexyl) phthalate accelerates atherosclerosis in apolipoprotein E-deficient mice.
    Archives of toxicology, 2016, Volume: 90, Issue:1

    Topics: Adipose Tissue, White; Adiposity; Animals; Apolipoproteins E; Atherosclerosis; Cell Line; Cholesterol; Diethylhexyl Phthalate; Disease Models, Animal; Disease Progression; Endothelial Cells; Genetic Predisposition to Disease; Humans; Inflammation Mediators; Lipoproteins, LDL; Liver; Macrophages; Male; Mice, Knockout; Phenotype; Plasticizers; Risk Assessment; Time Factors

2016
TMT predator odor activated neural circuit in C57BL/6J mice indicates TMT-stress as a suitable model for uncontrollable intense stress.
    Brain research, 2015, Mar-02, Volume: 1599

    Topics: Animals; Anxiety; Brain; Cell Count; Diethylhexyl Phthalate; Disease Models, Animal; Immunohistochemistry; Male; Mice, Inbred C57BL; Neural Pathways; Neurons; Odorants; Physical Stimulation; Predatory Behavior; Proto-Oncogene Proteins c-fos; Stress, Psychological; Thiazoles

2015
Thymic Stromal Lymphopoietin Neutralization Inhibits the Immune Adjuvant Effect of Di-(2-Ethylhexyl) Phthalate in Balb/c Mouse Asthma Model.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Adjuvants, Immunologic; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Diethylhexyl Phthalate; Disease Models, Animal; Immunoglobulin G; Male; Mice; Mice, Inbred BALB C; Neutralization Tests; Ovalbumin; Thymic Stromal Lymphopoietin

2016
Manipulation of pre and postnatal androgen environments and anogenital distance in rats.
    Toxicology, 2016, Aug-10, Volume: 368-369

    Topics: Androgen Antagonists; Androgens; Animals; Diethylhexyl Phthalate; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Flutamide; Male; Organ Size; Penis; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Rats; Spermatids; Testis; Testosterone

2016
26-Week carcinogenicity study of di-isodecyl phthalate by dietary administration to CB6F1-rasH2 transgenic mice.
    Archives of toxicology, 2011, Volume: 85, Issue:1

    Topics: Adenoma, Liver Cell; Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; Clofibrate; Diethylhexyl Phthalate; Disease Models, Animal; Female; Genes, ras; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Mice; Mice, Transgenic; Phthalic Acids; Pyrimidines; Time Factors

2011
Evaluation of the direct toxicity of trioctyltrimellitate (TOTM), di(2-ethylhexyl) phthalate (DEHP) and their hydrolysis products on isolated rat hepatocytes.
    The International journal of artificial organs, 2004, Volume: 27, Issue:11

    Topics: Animals; Benzoates; Cell Survival; Cells, Cultured; Diethylhexyl Phthalate; Disease Models, Animal; Hepatocytes; Hydrogen Peroxide; L-Lactate Dehydrogenase; Male; Probability; Rats; Rats, Wistar; Risk Factors

2004
Airway inflammation and adjuvant effect after repeated airborne exposures to di-(2-ethylhexyl)phthalate and ovalbumin in BALB/c mice.
    Toxicology, 2007, Jun-03, Volume: 235, Issue:1-2

    Topics: Adjuvants, Immunologic; Aerosols; Aluminum Hydroxide; Animals; Bronchoalveolar Lavage Fluid; Cells, Cultured; Cytokines; Diethylhexyl Phthalate; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Female; Humans; Immunoglobulin E; Immunoglobulin G; Inflammation; Inhalation Exposure; Lymphocytes; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Plasticizers; Respiratory Hypersensitivity; Risk Assessment

2007
Promotion of hepatocellular foci and adenomas by di(2-ethylhexyl) phthalate and phenobarbital in C3H/HeNCr mice following exposure to N-nitrosodiethylamine at 15 days of age.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1994, Volume: 45, Issue:7

    Topics: Adenoma, Liver Cell; Animals; Diethylhexyl Phthalate; Diethylnitrosamine; Disease Models, Animal; Female; Incidence; Liver Neoplasms; Male; Mice; Mice, Inbred C3H; Phenobarbital

1994
Effects of peroxisome proliferators and/or hypothyroidism on xenobiotic-metabolizing enzymes in rat testis.
    Chemico-biological interactions, 1997, May-02, Volume: 104, Issue:2-3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arylsulfotransferase; Aspirin; Caprylates; Catalase; Clofibrate; Diet; Diethylhexyl Phthalate; Disease Models, Animal; Epoxide Hydrolases; Fluorocarbons; Glucuronosyltransferase; Glutathione Peroxidase; Glutathione Transferase; Hypolipidemic Agents; Hypothyroidism; Male; Microbodies; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Testis

1997