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diethylhexyl phthalate and Chemical and Drug Induced Liver Injury

diethylhexyl phthalate has been researched along with Chemical and Drug Induced Liver Injury in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's1 (5.88)18.2507
2000's2 (11.76)29.6817
2010's6 (35.29)24.3611
2020's7 (41.18)2.80

Authors

AuthorsStudies
Cui, W; Fang, H; Han, X; Jia, X; Li, H; Li, J; Li, Y; Liu, Z; Ma, N; Tang, S; Wang, L; Wang, X; Xu, M; Yang, H; Zhang, Q; Zhang, X1
Guan, SY; Jin, HW; Kang, Z; Li, G; Na, XL; Wu, Q; Zhang, JT; Zhang, YB; Zhao, CY1
Abd-Alhameed, EK; Al-Thubiani, WS; Althagafy, HS; Hassanein, EHM; Ibrahim, IM1
Antonijević Miljaković, E; Antonijević, B; Baralić, K; Božić, D; Buha Djordjevic, A; Bulat, Z; Ćurčić, M; Javorac, D; Pavić, A; Radaković, N; Živančević, K; Đukić-Ćosić, D1
Fang, J; Geng, X; Jia, X; Li, Y; Ma, N; Xu, M; Yang, H; Zhang, Q1
Flaws, JA; Irudayaraj, J; Rattan, S; Wen, Y1
Chen, Y; Ding, Y; Feng, W; Mao, G; Qiu, X; Wu, X; Xu, T; Xu, X; Yang, L; Zhao, T1
Han, Y; Li, JL; Li, XN; Talukder, M; Zhang, C; Zhang, Q; Zhao, Y1
Chen, Y; Huang, Y; Li, Y; Liu, J; Wang, W; Wu, C; Xie, H; Ye, Y; Zeng, J; Zhang, H; Zhang, W; Zhu, J1
Fan, JH; Li, JL; Li, XN; Luo, Y; Talukder, M; Zhao, Y; Zuo, YZ1
Lo, D; Wang, YT; Wu, MC1
Antoccia, A; Azzalin, G; Di Masi, A; Di Virgilio, A; Eusepi, A; Lorenzetti, S; Macino, G; Magrelli, A; Mantovani, A; Maranghi, F; Marcoccia, D; Moracci, G; Romeo, A; Salvatore, M; Tanzarella, C; Taruscio, D; Tassinari, R; Tassinari, V; Tosto, F; Viganotti, M1
Han, SY; Kang, TS; Kim, HS; Kim, NY; Kim, SH; Kim, TH; Kwack, SJ; Lee, BM; Lee, E; Lee, J; Park, KL; Patra, N; Shin, MO1
Eilers, P; Ledent, E; Renard, D; Tibaldi, F; Vandenhende, F1
Bendikov, EA; Gorenkov, RV; Liubchenko, PN; Petrakov, AV1
Brunet, C; Courbon, F; Dine, T; Gressier, B; Houin, G; Luyckx, M; Nogarede, S; Plusquellec, Y; Souhait, J; Vanpoucke, J1
Butterworth, BE; Smith-Oliver, T1

Reviews

1 review(s) available for diethylhexyl phthalate and Chemical and Drug Induced Liver Injury

ArticleYear
Promising hepatoprotective effects of lycopene in different liver diseases.
    Life sciences, 2022, Dec-01, Volume: 310

    Topics: Antioxidants; Carotenoids; Chemical and Drug Induced Liver Injury; Diethylhexyl Phthalate; Humans; Lycopene

2022

Trials

1 trial(s) available for diethylhexyl phthalate and Chemical and Drug Induced Liver Injury

ArticleYear
A pharmacokinetic interpretation of increasing concentrations of DEHP in haemodialysed patients.
    Medical engineering & physics, 2000, Volume: 22, Issue:3

    Topics: Adult; Aged; Area Under Curve; Body Fluid Compartments; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Diethylhexyl Phthalate; Environmental Exposure; Environmental Monitoring; Female; Humans; Kidney Failure, Chronic; Liver Diseases; Male; Middle Aged; Models, Biological; Plasticizers; Polyvinyl Chloride; Renal Dialysis

2000

Other Studies

15 other study(ies) available for diethylhexyl phthalate and Chemical and Drug Induced Liver Injury

ArticleYear
Role of Hepatocyte- and Macrophage-Specific
    Environmental health perspectives, 2022, Volume: 130, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Diethylhexyl Phthalate; Hepatocytes; Macrophages; Mice

2022
Di(2-ethylhexyl) phthalate disturbs cholesterol metabolism through oxidative stress in rat liver.
    Environmental toxicology and pharmacology, 2022, Volume: 95

    Topics: Alanine Transaminase; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cholesterol; Diethylhexyl Phthalate; Lipoproteins, HDL; Liver; Malondialdehyde; Mixed Function Oxygenases; Oxidative Stress; Phthalic Acids; Rats; Rats, Sprague-Dawley

2022
Comprehensive investigation of hepatotoxicity of the mixture containing phthalates and bisphenol A.
    Journal of hazardous materials, 2023, 03-05, Volume: 445

    Topics: Animals; Benzhydryl Compounds; Chemical and Drug Induced Liver Injury; Dibutyl Phthalate; Diethylhexyl Phthalate; Phthalic Acids; Rats; Zebrafish

2023
Hepatotoxicity study of combined exposure of DEHP and ethanol: A comprehensive analysis of transcriptomics and metabolomics.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 141

    Topics: Animals; Chemical and Drug Induced Liver Injury; Diethylhexyl Phthalate; Drug Synergism; Ethanol; Fatty Acids, Unsaturated; Gene Expression Profiling; Lipid Metabolism; Liver; Male; Metabolomics; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptors; Signal Transduction; Transcriptome

2020
Multi and transgenerational epigenetic effects of di-(2-ethylhexyl) phthalate (DEHP) in liver.
    Toxicology and applied pharmacology, 2020, 09-01, Volume: 402

    Topics: Animals; Chemical and Drug Induced Liver Injury; Diethylhexyl Phthalate; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Endocrine Disruptors; Epigenesis, Genetic; Female; Gene Expression Regulation; Male; Maternal Exposure; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction

2020
Di-(2-ethylhexyl) phthalate-induced hepatotoxicity exacerbated type 2 diabetes mellitus (T2DM) in female pubertal T2DM mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2021, Volume: 149

    Topics: Animals; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diethylhexyl Phthalate; Environmental Pollutants; Female; Male; Mice; Mice, Inbred ICR; Principal Component Analysis

2021
Di(2-ethylhexyl) phthalate induced hepatotoxicity in quail (Coturnix japonica) via modulating the mitochondrial unfolded protein response and NRF2 mediated antioxidant defense.
    The Science of the total environment, 2019, Feb-15, Volume: 651, Issue:Pt 1

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Coturnix; Diethylhexyl Phthalate; Environmental Pollutants; NF-E2-Related Factor 2; Oxidative Stress; Unfolded Protein Response

2019
The Increase of ROS Caused by the Interference of DEHP with JNK/p38/p53 Pathway as the Reason for Hepatotoxicity.
    International journal of environmental research and public health, 2019, 01-27, Volume: 16, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Female; Lipid Peroxidation; Male; Malondialdehyde; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Plasticizers; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Tumor Suppressor Protein p53

2019
Di-(2-ethylhexyl) phthalate (DEHP)-induced hepatotoxicity in quail (Coturnix japonica) via suppression of the heat shock response.
    Chemosphere, 2019, Volume: 228

    Topics: Animals; Chemical and Drug Induced Liver Injury; Coturnix; Diethylhexyl Phthalate; Ecotoxicology; Environmental Pollutants; Female; Heat-Shock Proteins; Heat-Shock Response; Humans; Liver; Signal Transduction

2019
Hepatoprotective effect of silymarin on di(2-ethylhexyl)phthalate (DEHP) induced injury in liver FL83B cells.
    Environmental toxicology and pharmacology, 2014, Volume: 38, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Cycle; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Diethylhexyl Phthalate; Environmental Pollutants; L-Lactate Dehydrogenase; Liver; Mice; Plasticizers; Protective Agents; Silymarin

2014
In utero exposure to di-(2-ethylhexyl) phthalate affects liver morphology and metabolism in post-natal CD-1 mice.
    Reproductive toxicology (Elmsford, N.Y.), 2010, Volume: 29, Issue:4

    Topics: alpha-Fetoproteins; Animals; beta Catenin; Chemical and Drug Induced Liver Injury; Cytoplasm; Diethylhexyl Phthalate; Environmental Pollutants; Fatty Liver; Female; Gene Expression; Liver; Liver Glycogen; Maternal Exposure; Mice; Mice, Inbred Strains; Pregnancy; Prenatal Exposure Delayed Effects; RNA, Messenger

2010
Functional role of phospholipase D (PLD) in di(2-ethylhexyl) phthalate-induced hepatotoxicity in Sprague-Dawley rats.
    Journal of toxicology and environmental health. Part A, 2010, Volume: 73, Issue:21-22

    Topics: Animals; Biomarkers; Blotting, Western; Body Weight; Cell Nucleus; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Immunohistochemistry; Liver; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Organ Size; Peroxisome Proliferator-Activated Receptors; Phospholipase D; Plasticizers; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Testis

2010
Joint detection of important biomarkers and optimal dose-response model using penalties.
    Statistics in medicine, 2007, Nov-30, Volume: 26, Issue:27

    Topics: Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Computer Simulation; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Humans; Least-Squares Analysis; Liver Diseases; Models, Biological; Rats

2007
[Functional state of the liver in workers exposed to multi-component chemical mixture in the production of plastic construction materials].
    Meditsina truda i promyshlennaia ekologiia, 1995, Issue:6

    Topics: Adult; Antipyrine; Chemical and Drug Induced Liver Injury; Construction Materials; Diethylhexyl Phthalate; Female; Humans; Liver Diseases; Male; Middle Aged; Occupational Diseases; Plastics; Polyvinyl Chloride

1995
Correlation of the carcinogenic potential of di(2-ethylhexyl)phthalate (DEHP) with induced hyperplasia rather than with genotoxic activity.
    Mutation research, 1987, Volume: 188, Issue:1

    Topics: Alanine Transaminase; Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; Diethylhexyl Phthalate; DNA Damage; DNA Repair; DNA Replication; Hyperplasia; Liver; Liver Regeneration; Male; Mice; Mice, Inbred Strains; Mutagenicity Tests; Phthalic Acids

1987