Page last updated: 2024-08-18

diethylhexyl phthalate and Aging

diethylhexyl phthalate has been researched along with Aging in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19905 (18.52)18.7374
1990's5 (18.52)18.2507
2000's5 (18.52)29.6817
2010's10 (37.04)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Li, J; Liu, R; Lu, L; Pu, Y; Shi, W; Yin, L; Zhang, H; Zhang, Y; Zhou, Q1
Han, L; Long, C; Shen, L; Wang, J; Wei, G; Wei, Y; Wu, S; Wu, Y; Zhao, T1
Legler, J; Wassenaar, PNH1
Adeogun, AO; Arukwe, A; Ibor, OR1
Bendisari, K; Boudalia, S; Bouzid, B; Chader, H; Iguer-Ouada, M; Latreche, B; Oudir, M1
Holahan, MR; Luu, BE; Smith, CA; Storey, KB1
How, CM; Li, SW; Liao, VH; Wei, CC; Yen, PL1
Bae, S; Hong, YC; Kim, JH; Lim, YH; Park, HY1
Braun, JM; Calafat, AM; Eliot, M; Lanphear, BP; Sathyanarayana, S; Watkins, DJ; Yolton, K1
Flaws, JA; Hannon, PR; Niermann, S1
Barlow, NJ; Furr, JR; Gray, CL; Gray, LE; Howdeshell, KL; Ostby, JS1
Chen, K; Li, S; Li, X; Liu, SV; Zhang, X1
Ban, JB; Sun, W; Sun, WX; Zhang, N; Zu, YK1
Tanaka, T1
Nañez, A; Richburg, JH1
Einarsson, S; Hultén, F; Karlsson, P; Ljungvall, K; Madej, A; Magnusson, U; Norrgren, L; Rodriguez-Martinez, H1
Beems, R; Brandt, RM; de Wit, J; Diderich, KE; Friedberg, EC; Garinis, GA; Gorgels, TG; Hoeijmakers, JH; Mitchell, JR; Niedernhofer, LJ; Tanaka, K; van der Horst, GT; van der Pluijm, I; van Oostrom, C; van Steeg, H; Velasco, S; Wijnhoven, SW1
Butterworth, KR; Gray, TJ1
Chang, YF; Pan, X; Rao, VV; Tsai, MJ1
Parmar, D; Seth, PK; Singh, GB; Srivastava, SP1
Dallner, G; Turunen, M1
Dallner, G; Sindelar, P; Turunen, M1
Heindel, JJ; Powell, CJ1
Bondesson, U; Gustafsson, J; Sjöberg, P1
Dostal, LA; Jenkins, WL; Schwetz, BA1
Darnerud, PO; Eriksson, P1
Bondesson, U; Kjellen, L; Lindquist, NG; Montin, G; Plöen, L; Sjöberg, P1

Reviews

1 review(s) available for diethylhexyl phthalate and Aging

ArticleYear
Systematic review and meta-analysis of early life exposure to di(2-ethylhexyl) phthalate and obesity related outcomes in rodents.
    Chemosphere, 2017, Volume: 188

    Topics: Adipose Tissue; Aging; Animals; Body Weight; Diethylhexyl Phthalate; Environmental Pollutants; Humans; Obesity; Plasticizers; Rodentia; Triglycerides

2017

Trials

1 trial(s) available for diethylhexyl phthalate and Aging

ArticleYear
Delayed effects on plasma concentration of testosterone and testicular morphology by intramuscular low-dose di(2-ethylhexyl)phthalate or oestradiol benzoate in the prepubertal boar.
    Theriogenology, 2005, Sep-15, Volume: 64, Issue:5

    Topics: Aging; Animals; Diethylhexyl Phthalate; Endocrine Disruptors; Estradiol; Injections, Intramuscular; Luteinizing Hormone; Male; Organ Size; Sexual Maturation; Swine; Testis; Testosterone; Time Factors

2005

Other Studies

25 other study(ies) available for diethylhexyl phthalate and Aging

ArticleYear
Di(2-ethylhexyl) phthalate induces reproductive toxicity and transgenerational reproductive aging in Caenorhabditis elegans.
    Environmental pollution (Barking, Essex : 1987), 2023, Nov-01, Volume: 336

    Topics: Aging; Animals; Caenorhabditis elegans; Diethylhexyl Phthalate; Female; Reproduction

2023
LncRNAs activate longevity regulation pathway due to aging of Leydig cells caused by DEHP exposure: A transcriptome-based study.
    Ecotoxicology and environmental safety, 2021, Volume: 209

    Topics: Aging; Animals; Diethylhexyl Phthalate; Endocrine Disruptors; Gene Expression Regulation; Humans; Leydig Cells; Longevity; Male; Mice; Phthalic Acids; RNA, Long Noncoding; Testis; Transcriptome

2021
Biphasic modulation of neuro- and interrenal steroidogenesis in juvenile African sharptooth catfish (Clarias gariepinus) exposed to waterborne di-(2-ethylhexyl) phthalate.
    General and comparative endocrinology, 2017, 12-01, Volume: 254

    Topics: Aging; Animals; Brain; Catfishes; Diethylhexyl Phthalate; Endocrine Disruptors; Environmental Exposure; Estradiol; Head Kidney; Liver; Phosphoproteins; RNA, Messenger; Steroids; Testosterone; Water Pollutants, Chemical

2017
Male rat exposure to low dose of di(2-ethylhexyl) phthalate during pre-pubertal, pubertal and post-pubertal periods: Impact on sperm count, gonad histology and testosterone secretion.
    Reproductive toxicology (Elmsford, N.Y.), 2018, Volume: 75

    Topics: Aging; Animals; Cell Count; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Environmental Pollutants; Leydig Cells; Male; Rats, Wistar; Sertoli Cells; Sexual Maturation; Spermatozoa; Testis; Testosterone

2018
Preadolescent Phthalate (DEHP) Exposure Is Associated With Elevated Locomotor Activity and Reward-Related Behavior and a Reduced Number of Tyrosine Hydroxylase Positive Neurons in Post-Adolescent Male and Female Rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2018, 10-01, Volume: 165, Issue:2

    Topics: Aging; Animals; Behavior, Animal; Brain; Conditioning, Operant; Diethylhexyl Phthalate; Dopamine; Dose-Response Relationship, Drug; Female; Locomotion; Male; Neurons; Rats, Long-Evans; Reward; Tyrosine 3-Monooxygenase

2018
Early life exposure to di(2-ethylhexyl)phthalate causes age-related declines associated with insulin/IGF-1-like signaling pathway and SKN-1 in Caenorhabditis elegans.
    Environmental pollution (Barking, Essex : 1987), 2019, Volume: 251

    Topics: Aging; Animals; Biomarkers; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Diethylhexyl Phthalate; DNA-Binding Proteins; Environmental Pollutants; Heat-Shock Proteins; Insulin; Insulin-Like Growth Factor I; Lipid Peroxidation; Lipofuscin; Longevity; Plasticizers; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Transcription Factors

2019
Diethylhexyl phthalates is associated with insulin resistance via oxidative stress in the elderly: a panel study.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Aged; Aged, 80 and over; Aging; Blood Glucose; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Pollutants; Fasting; Female; Humans; Insulin; Insulin Resistance; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Phthalic Acids; Regression Analysis; Sex Factors

2013
Variability and predictors of urinary concentrations of phthalate metabolites during early childhood.
    Environmental science & technology, 2014, Volume: 48, Issue:15

    Topics: Aging; Child, Preschool; Cross-Sectional Studies; Diethylhexyl Phthalate; Environmental Monitoring; Environmental Pollutants; Fasting; Female; Humans; Linear Models; Male; Multivariate Analysis; Ohio; Phthalic Acids; Prospective Studies; Reproducibility of Results

2014
Acute Exposure to Di(2-Ethylhexyl) Phthalate in Adulthood Causes Adverse Reproductive Outcomes Later in Life and Accelerates Reproductive Aging in Female Mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 150, Issue:1

    Topics: Aging; Animals; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Environmental Pollutants; Estrous Cycle; Female; Fertility; Follicular Atresia; Infertility, Female; Male; Mice, Inbred Strains; Ovarian Follicle; Pregnancy

2016
Transgenerational effects of Di (2-ethylhexyl) phthalate in the male CRL:CD(SD) rat: added value of assessing multiple offspring per litter.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 110, Issue:2

    Topics: Abnormalities, Drug-Induced; Aging; Animals; Animals, Newborn; Biotransformation; Data Interpretation, Statistical; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Female; Genitalia, Male; Gestational Age; Lactation; Litter Size; Male; Maternal Exposure; Nipples; No-Observed-Adverse-Effect Level; Organ Size; Phthalic Acids; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sample Size; Sexual Maturation; Sperm Count; Toxicity Tests; Weaning

2009
A new cultivation system for studying chemical effects on the lifespan of the fruit fly.
    Experimental gerontology, 2010, Volume: 45, Issue:2

    Topics: Aging; Animal Feed; Animals; Caloric Restriction; Diethylhexyl Phthalate; Drosophila melanogaster; Energy Metabolism; Equipment Design; Female; Housing, Animal; Longevity; Male; Plasticizers

2010
Perinatal exposure to Di-(2-ethylhexyl)-Phthalate leads to cognitive dysfunction and phospho-tau level increase in aged rats.
    Environmental toxicology, 2014, Volume: 29, Issue:5

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Cognition Disorders; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Insulin; Male; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Rats, Wistar; Signal Transduction; tau Proteins

2014
Reproductive and neurobehavioural toxicity study of bis(2-ethylhexyl) phthalate (DEHP) administered to mice in the diet.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:10

    Topics: Aging; Animals; Behavior, Animal; Birth Weight; Body Weight; Diet; Diethylhexyl Phthalate; Eating; Female; Litter Size; Male; Mice; Motor Activity; Nervous System; Plasticizers; Pregnancy; Reproduction; Sex Ratio

2002
Fas- or FasL-deficient mice display an increased sensitivity to nitrobenzene-induced testicular germ cell apoptosis.
    Toxicology letters, 2003, Mar-20, Volume: 139, Issue:1

    Topics: Aging; Animals; Apoptosis; Diethylhexyl Phthalate; Fas Ligand Protein; fas Receptor; Gene Deletion; Gene Expression Regulation; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitrobenzenes; Sertoli Cells; Signal Transduction; Spermatozoa; Testis

2003
Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.
    PLoS biology, 2007, Volume: 5, Issue:1

    Topics: Aging; Animals; Antioxidants; Cockayne Syndrome; Diethylhexyl Phthalate; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Fatty Acids; Genome; Glucose; Growth Hormone; Insulin-Like Growth Factor I; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Poly-ADP-Ribose Binding Proteins; Radiation, Ionizing; Somatotrophs; Xeroderma Pigmentosum Group A Protein

2007
Testicular atrophy produced by phthalate esters.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1980, Volume: 4

    Topics: Aging; Animals; Atrophy; Diethylhexyl Phthalate; Follicle Stimulating Hormone; Male; Organ Size; Phthalic Acids; Rats; Testis; Testosterone

1980
L-pipecolic acid oxidation in rat: subcellular localization and developmental study.
    Biochimica et biophysica acta, 1993, Jun-24, Volume: 1164, Issue:1

    Topics: Aging; Animals; Antimycin A; Brain; Diethylhexyl Phthalate; Enzyme Induction; Glucagon; Liver; Male; Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Sprague-Dawley; Rotenone; Subcellular Fractions

1993
Testicular toxicity of Di(2-ethylhexyl)phthalate in developing rats.
    Veterinary and human toxicology, 1995, Volume: 37, Issue:4

    Topics: Aging; Animals; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Ethylmorphine-N-Demethylase; gamma-Glutamyltransferase; Germ Cells; Glucuronidase; Isoenzymes; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Liver; Male; Organ Size; Rats; Rats, Wistar; Seminiferous Tubules; Spermatogenesis; Testis

1995
Elevation of ubiquinone content by peroxisomal inducers in rat liver during aging.
    Chemico-biological interactions, 1998, Nov-06, Volume: 116, Issue:1-2

    Topics: Aging; Animals; Cholesterol; Diethylhexyl Phthalate; Dolichols; Half-Life; Liver; Male; Microbodies; Oxidation-Reduction; Peroxisome Proliferators; Rats; Rats, Sprague-Dawley; Ubiquinone

1998
Induction of endogenous coenzyme Q biosynthesis by administration of peroxisomal inducers.
    BioFactors (Oxford, England), 1999, Volume: 9, Issue:2-4

    Topics: Aging; Animals; Aspirin; Clofibrate; Dehydroepiandrosterone; Diethylhexyl Phthalate; Intracellular Membranes; Liver; Male; Microbodies; Mitochondria, Liver; Organ Specificity; Organelles; Peroxisome Proliferators; Rats; Rats, Sprague-Dawley; Ubiquinone

1999
Phthalate ester effects on rat Sertoli cell function in vitro: effects of phthalate side chain and age of animal.
    Toxicology and applied pharmacology, 1992, Volume: 115, Issue:1

    Topics: Adenosine Triphosphate; Aging; Animals; Cells, Cultured; Cyclic AMP; Diethylhexyl Phthalate; Follicle Stimulating Hormone; Lactates; Male; Rats; Rats, Inbred F344; Sertoli Cells

1992
Metabolism of mono-(2-ethylhexyl)phthalate in fetal, neonatal and adult rat liver.
    Biology of the neonate, 1988, Volume: 53, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Cytochrome P-450 CYP4A; Diethylhexyl Phthalate; Female; Fetus; Gas Chromatography-Mass Spectrometry; Inactivation, Metabolic; Male; Microsomes, Liver; Mixed Function Oxygenases; Phthalic Acids; Pregnancy; Rats; Rats, Inbred Strains

1988
Hepatic peroxisome proliferation and hypolipidemic effects of di(2-ethylhexyl)phthalate in neonatal and adult rats.
    Toxicology and applied pharmacology, 1987, Volume: 87, Issue:1

    Topics: Aging; Animals; Body Weight; Cholesterol; Diethylhexyl Phthalate; Kidney; Lipids; Liver; Male; Microbodies; Organ Size; Phthalic Acids; Rats; Rats, Inbred Strains; Triglycerides

1987
Distribution and retention of some chlorinated hydrocarbons and a phthalate in the mouse brain during the pre-weaning period.
    Toxicology, 1985, Volume: 37, Issue:3-4

    Topics: Administration, Oral; Aging; Animals; Animals, Newborn; Autoradiography; Body Weight; Brain; Carbon Radioisotopes; Diethylhexyl Phthalate; Female; Liver; Male; Mice; Myelin Sheath; Organ Size; Phthalic Acids; Polychlorinated Biphenyls; Tissue Distribution

1985
Kinetics of di-(2-ethylhexyl) phthalate in immature and mature rats and effect on testis.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:1

    Topics: Aging; Animals; Blood Proteins; Chromatography, Gas; Diethylhexyl Phthalate; Half-Life; Kinetics; Male; Phthalic Acids; Protein Binding; Rats; Rats, Inbred Strains; Testis; Time Factors

1985