diethylcarbamazine has been researched along with Onchocerciasis in 228 studies
Diethylcarbamazine: An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Onchocerciasis: Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-nine onchocerciasis patients with ocular involvement were randomly assigned to receive either 12 mg of ivermectin in a single dose or 1300 mg of diethylcarbamazine over eight days or matching placebo capsules." | 9.06 | The chemotherapy of onchocerciasis. XI. A double-blind comparative study of ivermectin, diethylcarbamazine and placebo in human onchocerciasis in northern Ghana. ( Awadzi, K; Aziz, MA; Dadzie, KY; Fulford, AJ; Gilles, HM; Schulz-Key, H, 1986) |
| "The ocular changes that occur with diethylcarbamazine treatment of onchocerciasis seriously restrict its usefulness." | 9.06 | Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine. ( Aziz, MA; Cupp, EW; D'Anna, SA; Greene, BM; Keyvan-Larijani, E; Murphy, RP; Newland, HS; Taylor, HR; White, AT, 1986) |
| "We compared ivermectin with diethylcarbamazine for the treatment of onchocerciasis in a double-blind, placebo-controlled trial." | 9.05 | Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis. ( Aziz, MA; Cupp, EW; D'Anna, SA; Goldschmidt, LP; Greene, BM; Murphy, RP; Newland, HS; Schulz-Key, H; Taylor, HR; White, AT, 1985) |
| "In a double-blind controlled clinical trial comparing the safety and efficacy of oral diethylcarbamazine citrate (DEC) with topical DEC for the treatment of onchocerciasis twenty men with moderate skin-snip microfilarial counts received daily therapy for 1 week, then weekly therapy for the rest of 6 months." | 9.05 | Controlled clinical trial of oral and topical diethylcarbamazine in treatment of onchocerciasis. ( Greene, BM; Langham, ME; Taylor, HR, 1980) |
| "Flubendazole, an injectable benzimidazole drug, was compared with diethylcarbamazine (DEC) in a prospective double-blind study of the treatment of onchocerciasis." | 9.05 | Comparison of flubendazole and diethylcarbamazine in treatment of onchocerciasis. ( Beltran-Hernandez, F; Dominguez-Vazquez, A; Greene, BM; Murphy, RP; Rivas-Alcala, AR; Ruvalcaba-Macias, AM; Taylor, HR, 1983) |
| "In a randomised double-blind study, ivermectin was compared with diethylcarbamazine (DEC) and placebo in the treatment of onchocerciasis in 30 male patients from Mali with moderate to heavy Onchocerca volvulus infections and ocular involvement." | 9.05 | Double-blind study of ivermectin and diethylcarbamazine in African onchocerciasis patients with ocular involvement. ( Aziz, M; Basset, D; Beauvais, B; Derouin, F; Gaxotte, P; Ginoux, J; Lariviere, M; Schulz-Key, H; Vingtain, P; Weimann, D, 1985) |
| "A double-masked, controlled clinical trial was conducted in Guatemala to assess the safety and efficacy of diethylcarbamazine (DEC) lotion as compared to placebo lotion in the treatment of onchocerciasis." | 9.05 | Chemotherapy of onchocerciasis: a controlled clinical trial of topical diethylcarbamazine (DEC) in Guatemala. ( Beltranena, F; de Stahl, EM; Figueroa, LN; Langham, ME; Taylor, HR, 1980) |
| "Guatermalan volunteers with onchocerciasis were given a dose of diethylcarbamazine to learn if this caused migration of microfilariae of Onchocerca volvulus into urine, blood, and sputum." | 9.04 | Onchocerciasis in Guatemala. II. Microfilariae in urine, blood, and sputum after diethylcarbamazine. ( Anderson, RI; Buck, AA; Fazen, LE, 1975) |
| "As part of a baseline data collection for assessing the impact of the African Programme for Onchocerciasis Control, to evaluate the diethylcarbamazine (DEC) patch test in determining the endemicity of onchocerciasis." | 7.74 | Evaluation of the diethylcarbamazine patch to evaluate onchocerciasis endemicity in Central Africa. ( Bissek, AC; Boussinesq, M; Enyong, P; Fobi, G; Kobangue, L; Kombila, M; Mbina, JR; Noma, M; Ozoh, G; Sékétéli, A, 2007) |
| "Topical application of diethylcarbamazine (DEC) cream was tested as a method of diagnosis in patients with onchocerciasis." | 7.67 | The use of diethylcarbamazine cream in the diagnosis of onchocerciasis. ( Kaiser, A; Newland, HS; Taylor, HR, 1987) |
| "Two patients, one with Bancroftian filariasis and the other with onchocerciasis, and two healthy controls were treated with diethylcarbamazine (DEC)." | 7.67 | Increase in natural killer cell activity during diethylcarbamazine treatment of patients with filariasis. ( Bygbjerg, IC; Pedersen, BK; Svenson, M, 1987) |
| "The response of 45 severely infected onchocerciasis patients to relatively high doses of diethylcarbamazine citrate (DEC-C) has been determined." | 7.67 | The Onchocerca volvulus micro- and macrofilarial responses in onchocerciasis patients to increased dosage of diethylcarbamazine. ( Beltranena, F; Langham, ME, 1985) |
| "464 persons of whom 189 proved to be infected with microfilariae of Wuchereria bancrofti and/or Onchocerca volvulus were examined for adverse reactions due to diethylcarbamazine, which was administered during a filariasis control campaign." | 7.66 | Studies on Bancroftian filariasis in Liberia, West Africa. IV. Notes on side effects observed during a diethylcarbamazine treatment campaign in a rural area endemic for Wuchereria bancrofti and Onchocerca volvulus. ( Chlebowsky, HO; Zielke, E, 1980) |
| "Eighteen patients, moderately to heavily infected with onchocerciasis, were treated with a standard course of diethylcarbamazine citrate (DEC-C)." | 7.66 | Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate. ( Anderson, J; Bird, AC; el-Sheikh, H; Fuglsang, H, 1980) |
| "Specimens of lymph nodes from eight patients with onchocerciasis after treatment with diethylcarbamazine (DEC) were studied by electron microscopy." | 7.66 | Ultrastructural evidence for eosinophil-parasite adherence (EPA) reaction in human onchocercal lymphadenitis in the early period following diethylcarbamazine treatment. ( Albiez, EJ; Büttner, DW; Rácz, P; Tenner-Rácz, K, 1982) |
| "One hundred patients with onchocerciasis were treated with diethylcarbamazine: a single course of treatment led to clinical cure in 48% of the patients; no means of anticipating which patients might require only a single course of treatment was found." | 7.65 | Onchocerciasis treated with diethylcarbamazine. ( Rée, GH, 1977) |
| "A single 10-14 day course of diethylcarbamazine (DEC) was given under betamethazone cover to 18 patients (Group A) with ocular onchocerciasis, and the effects were studied in detail over 1-2 years." | 7.65 | Effects of diethylcarbamazine on ocular onchocerciasis. ( Anderson, J; de C Marshall, TF; Fuglsang, H, 1976) |
| "Nine Nigerians with severe onchocerciasis who were treated with diethylcarbamazine developed clinical changes, ranging in severity from mild itching to distress, cough, and syncope." | 7.65 | Dangerous reactions to treatment of onchocerciasis with diethylcarbamazine. ( Bryceson, AD; Pope, HM; Warrell, DA, 1977) |
| "No other short-course oral treatment for onchocerciasis has been demonstrated to have macrofilaricidal activity." | 7.30 | A randomized, open-label study of the tolerability and efficacy of one or three daily doses of ivermectin plus diethylcarbamazine and albendazole (IDA) versus one dose of ivermectin plus albendazole (IA) for treatment of onchocerciasis. ( Doe, F; Dubben, B; Fetcho, N; Fischer, K; Fischer, PU; Gordor, S; Goss, CW; Gyasi, ME; Hoerauf, A; Hong, AR; Kanza, E; King, CL; Laryea, R; Lew, D; Opoku, NO; Seidu, MA; Weil, GJ, 2023) |
| " Clinical adverse reactions were recorded in four ivermectin, ten DEC and three placebo patients." | 6.66 | A double-blind comparison of the efficacy and safety of ivermectin and diethylcarbamazine in a placebo controlled study of Senegalese patients with onchocerciasis. ( Aziz, MA; Badiane, S; Diallo, JS; Diallo, S; Diop-Mar, I; Gaxotte, P; Lariviere, M; N'Dir, O; Py, D; Schulz-Key, H, 1986) |
| "Four drug regimens for treating onchocerciasis were compared in a double-blind study in persons from an endemic area in southern Mexico." | 6.65 | Chemotherapy of onchocerciasis: a controlled comparison of mebendazole, levamisole, and diethylcarbamazine. ( Beltrán, F; Domíguez-Vázquez, A; Greene, BM; Lugo-Pfeiffer, C; Mackenzie, CD; Rivas-Alcalá, AR; Ruvalcaba-Macías, AM; Taylor, HR, 1981) |
| "Diethylcarbamazine (DEC) was applied as a "patch test" to the skin of 45 patients with onchocerciasis in the Southern Sudan." | 5.27 | A diagnostic "patch test" for onchocerciasis using topical diethylcarbamazine. ( Connor, DH; Gibson, DW; Ribas, J; Ross, M; Stingl, P, 1984) |
| "Hypotension, fever, adenitis and pruritus were all correlated with infection intensity in these patients while arthralgia and tachycardia were not." | 5.27 | The Mazzotti reaction following treatment of onchocerciasis with diethylcarbamazine: clinical severity as a function of infection intensity. ( Awadzi, K; Francis, H; Ottesen, EA, 1985) |
| "Diethylcarbamazine was given as eye drops in varying concentrations in a half-log dilution series from 1." | 5.26 | Effects of various concentrations of diethylcarbamazine citrate applied as eye drops in ocular onchocerciasis, and the possibilities of improved therapy from continuous non-pulsed delivery. ( Anderson, J; Fuglsang, H; Jones, BR, 1978) |
| "Fifty-nine onchocerciasis patients with ocular involvement were randomly assigned to receive either 12 mg of ivermectin in a single dose or 1300 mg of diethylcarbamazine over eight days or matching placebo capsules." | 5.06 | The chemotherapy of onchocerciasis. XI. A double-blind comparative study of ivermectin, diethylcarbamazine and placebo in human onchocerciasis in northern Ghana. ( Awadzi, K; Aziz, MA; Dadzie, KY; Fulford, AJ; Gilles, HM; Schulz-Key, H, 1986) |
| "Thirty adult male nodule carriers from a hyperendemic onchocerciasis area in the Liberian rain forest were treated with high doses of diethylcarbamazine (30 mg/kg/d) over one week." | 5.06 | Effects of high doses of diethylcarbamazine on adult Onchocerca volvulus examined by the collagenase technique and by histology. ( Albiez, EJ; Büttner, DW; Greene, BM; Kaiser, A; Newland, HS; Taylor, HR; Walter, G; White, AT, 1988) |
| "The ocular changes that occur with diethylcarbamazine treatment of onchocerciasis seriously restrict its usefulness." | 5.06 | Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine. ( Aziz, MA; Cupp, EW; D'Anna, SA; Greene, BM; Keyvan-Larijani, E; Murphy, RP; Newland, HS; Taylor, HR; White, AT, 1986) |
| "In a double-blind controlled clinical trial comparing the safety and efficacy of oral diethylcarbamazine citrate (DEC) with topical DEC for the treatment of onchocerciasis twenty men with moderate skin-snip microfilarial counts received daily therapy for 1 week, then weekly therapy for the rest of 6 months." | 5.05 | Controlled clinical trial of oral and topical diethylcarbamazine in treatment of onchocerciasis. ( Greene, BM; Langham, ME; Taylor, HR, 1980) |
| "In a randomised double-blind study, ivermectin was compared with diethylcarbamazine (DEC) and placebo in the treatment of onchocerciasis in 30 male patients from Mali with moderate to heavy Onchocerca volvulus infections and ocular involvement." | 5.05 | Double-blind study of ivermectin and diethylcarbamazine in African onchocerciasis patients with ocular involvement. ( Aziz, M; Basset, D; Beauvais, B; Derouin, F; Gaxotte, P; Ginoux, J; Lariviere, M; Schulz-Key, H; Vingtain, P; Weimann, D, 1985) |
| "In a single-blind comparative study of diethylcarbamazine (DEC) and metrifonate against onchocerciasis, 20 patient received a total dose of 6." | 5.05 | The chemotherapy of onchocerciasis iii. A comparative study of diethylcarbamazide (DEC) and metrifonate. ( Awadzi, K; Gilles, HM, 1980) |
| "We compared ivermectin with diethylcarbamazine for the treatment of onchocerciasis in a double-blind, placebo-controlled trial." | 5.05 | Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis. ( Aziz, MA; Cupp, EW; D'Anna, SA; Goldschmidt, LP; Greene, BM; Murphy, RP; Newland, HS; Schulz-Key, H; Taylor, HR; White, AT, 1985) |
| "Flubendazole, an injectable benzimidazole drug, was compared with diethylcarbamazine (DEC) in a prospective double-blind study of the treatment of onchocerciasis." | 5.05 | Comparison of flubendazole and diethylcarbamazine in treatment of onchocerciasis. ( Beltran-Hernandez, F; Dominguez-Vazquez, A; Greene, BM; Murphy, RP; Rivas-Alcala, AR; Ruvalcaba-Macias, AM; Taylor, HR, 1983) |
| "Counts of microfilariae in the skin, and histological and electronmicroscopic procedures have been used to analyze the response of onchocerciasis patients to diethylcarbamazine citrate (DEC) given either orally or topically." | 5.04 | A transepidermal chemotherapy of onchocerciasis. ( Langham, ME; Richardson, R; Traub, ZD, 1978) |
| "Since diethylcarbamazine at the dosages used to treat filarial infections has little direct toxicity, most of the post-treatment reactions (termed Mazzotti reactions in onchocerciasis) result from the immunological inflammatory mechanisms activated in the process of clearing and killing the skin-swelling or blood-borne microfilariae." | 4.77 | Description, mechanisms and control of reactions to treatment in the human filariases. ( Ottesen, EA, 1987) |
| "Treatment of onchocerciasis with diethylcarbamazine (DEC) or ivermectin is associated with a posttreatment reaction characterized by fever, tachycardia, hypotension, lymphadenopathy, and pruritus." | 3.71 | Bacterial endosymbionts of Onchocerca volvulus in the pathogenesis of posttreatment reactions. ( Awadzi, K; Keiser, PB; Nutman, TB; Ottesen, EA; Reynolds, SM; Taylor, MJ, 2002) |
| "In persons with onchocerciasis, topical application of the anthelminthic diethylcarbamazine (DEC) induces clinical and histologic responses similar to acute papular onchodermatitis, including recruitment of eosinophils to the skin." | 3.70 | Eotaxin expression in Onchocerca volvulus-induced dermatitis after topical application of diethylcarbamazine. ( Boatin, BA; Gilles, AA; Higgins, AW; Pearlman, E; Toé, L; Unnasch, TR, 1999) |
| "In the last ten years ivermectin appeared an efficient and safe alternative to diethylcarbamazine which is known to induce severe adverse reactions in loiasis, including encephalitis." | 3.69 | [Secondary effects of the treatment of hypermicrofilaremic loiasis using ivermectin]. ( Boussinesq, M; Chippaux, JP; Ducorps, M; Gardon, J; Gardon-Wendel, N; Ndong, W; Ranque, S; Schneider, D, 1995) |
| "Potential diagnostic indicators of onchocerciasis (subcutaneous nodules, depigmentation or leopard skin, microfilaruria, diethylcarbamazine patch test positivity, excoriations, and pruritus) were evaluated in a rain forest region of southern Cameroon for usefulness in rapid assessment of onchocerciasis endemicity in communities." | 3.69 | Evaluation of alternate methods of rapid assessment of endemicity of Onchocerca volvulus in communities in southern Cameroon. ( Cline, BL; Kollo, B; Mather, FJ, 1995) |
| "The eosinophil survival assay was used to quantitate cytokines in 17 serial serum samples from 10 patients treated for onchocerciasis with diethylcarbamazine." | 3.69 | Elevations in granulocyte-macrophage colony-stimulating factor and interleukin-5 levels precede posttreatment eosinophilia in onchocerciasis. ( Awadzi, K; Bartemes, KR; Gleich, GJ; Hagan, JB; Kita, H; Nutman, TB; Ottesen, EA, 1996) |
| " Skin biopsies were obtained from adult Liberian and Ugandan patients with generalized onchocerciasis after exposure to topically applied diethylcarbamazine (DEC) and from untreated patients." | 3.69 | Neutrophil granule proteins: evidence for the participation in the host reaction to skin microfilariae of Onchocerca volvulus after diethylcarbamazine administration. ( Büttner, DW; Gutiérrez-Peña, EJ; Knab, J, 1996) |
| "To define the changes in antibody response to Onchocerca volvulus antigens after treatment of patients with onchocerciasis, IgG and IgE antibodies were examined quantitatively and qualitatively in 21 patients and 3 control individuals before and sequentially for 14 days after treatment with diethylcarbamazine." | 3.68 | Changes in antibody profile after treatment of human onchocerciasis. ( Awadzi, K; Francis, HL; Lee, SJ; Nutman, TB; Ottesen, EA, 1990) |
| "Onchocerciasis patients treated with diethylcarbamazine often undergo a severe inflammatory response, the Mazzotti reaction." | 3.68 | Eosinophil degranulation. An immunologic determinant in the pathogenesis of the Mazzotti reaction in human onchocerciasis. ( Ackerman, SJ; Awadzi, K; Francis, H; Gleich, GJ; Kephart, GM; Ottesen, EA, 1990) |
| "The response of 45 severely infected onchocerciasis patients to relatively high doses of diethylcarbamazine citrate (DEC-C) has been determined." | 3.67 | The Onchocerca volvulus micro- and macrofilarial responses in onchocerciasis patients to increased dosage of diethylcarbamazine. ( Beltranena, F; Langham, ME, 1985) |
| "The Mazzotti reaction is a frequent complication in patients with onchocerciasis being treated with diethylcarbamazine (DEC); and more severe manifestations of this reaction may be unacceptable in many patients." | 3.67 | Does dexamethasone suppress the Mazzotti reaction in patients with onchocerciasis? ( Connor, DH; Gibson, DW; Pierce, PF; Ribas, JL; Ross, MA; Stingl, P; Straessle, T, 1988) |
| "Two patients, one with Bancroftian filariasis and the other with onchocerciasis, and two healthy controls were treated with diethylcarbamazine (DEC)." | 3.67 | Increase in natural killer cell activity during diethylcarbamazine treatment of patients with filariasis. ( Bygbjerg, IC; Pedersen, BK; Svenson, M, 1987) |
| "The treatment of onchocerciasis using diethylcarbamazine and suramin sodium, which can kill different stages of the parasite, Onchocerca volvulus, remains unsatisfactory." | 3.67 | Recent developments in the treatment of onchocerciasis. ( Taylor, HR, 1984) |
| "6% diethylcarbamazine citrate in Nivea lotion as a diagnostic test for onchocerciasis was studied in 473 Liberians aged 2 to 55 years." | 3.67 | The use of a topical Mazzotti test in the diagnosis of onchocerciasis. ( Kilian, HD, 1988) |
| "Over the past 35 yr, diethylcarbamazine (DEC) has been the most widely used agent for the treatment of filarial diseases, particularly in onchocerciasis." | 3.67 | Onchocerca volvulus. Monoclonal anti-idiotype antibody as antigen signal for the microfilaricidal cytotoxicity of diethylcarbamazine-treated platelets. ( Capron, A; Cesbron, JY; Grzych, JM; Hayasaki, M; Joseph, M; Lutsch, C, 1988) |
| "Lymph nodes (LN) from 50 patients with generalized onchocerciasis with or without diethylcarbamazine treatment and LN of patients with untreated localized onchocerciasis were studied." | 3.66 | Immunopathologic aspects in human onchocercal lymphadenitis. ( Albiez, EJ; Buttner, DW; Luther, B; Racz, P; Tenner-Racz, K, 1983) |
| "464 persons of whom 189 proved to be infected with microfilariae of Wuchereria bancrofti and/or Onchocerca volvulus were examined for adverse reactions due to diethylcarbamazine, which was administered during a filariasis control campaign." | 3.66 | Studies on Bancroftian filariasis in Liberia, West Africa. IV. Notes on side effects observed during a diethylcarbamazine treatment campaign in a rural area endemic for Wuchereria bancrofti and Onchocerca volvulus. ( Chlebowsky, HO; Zielke, E, 1980) |
| "The effect of graded doses of diethylcarbamazine on the concentration of microfilariae in the hydrocoele fluid, urine and skin of patients suffering from onchocerciasis was studied." | 3.66 | Effect of diethylcarbamazine on the concentration of Onchocerca volvulus microfilariae in hydrocoele fluid and urine. ( Kale, OO, 1979) |
| "Eighteen patients, moderately to heavily infected with onchocerciasis, were treated with a standard course of diethylcarbamazine citrate (DEC-C)." | 3.66 | Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate. ( Anderson, J; Bird, AC; el-Sheikh, H; Fuglsang, H, 1980) |
| "Specimens of lymph nodes from eight patients with onchocerciasis after treatment with diethylcarbamazine (DEC) were studied by electron microscopy." | 3.66 | Ultrastructural evidence for eosinophil-parasite adherence (EPA) reaction in human onchocercal lymphadenitis in the early period following diethylcarbamazine treatment. ( Albiez, EJ; Büttner, DW; Rácz, P; Tenner-Rácz, K, 1982) |
| "A single 10-14 day course of diethylcarbamazine (DEC) was given under betamethazone cover to 18 patients (Group A) with ocular onchocerciasis, and the effects were studied in detail over 1-2 years." | 3.65 | Effects of diethylcarbamazine on ocular onchocerciasis. ( Anderson, J; de C Marshall, TF; Fuglsang, H, 1976) |
| "Nine Nigerians with severe onchocerciasis who were treated with diethylcarbamazine developed clinical changes, ranging in severity from mild itching to distress, cough, and syncope." | 3.65 | Dangerous reactions to treatment of onchocerciasis with diethylcarbamazine. ( Bryceson, AD; Pope, HM; Warrell, DA, 1977) |
| "One hundred patients with onchocerciasis were treated with diethylcarbamazine: a single course of treatment led to clinical cure in 48% of the patients; no means of anticipating which patients might require only a single course of treatment was found." | 3.65 | Onchocerciasis treated with diethylcarbamazine. ( Rée, GH, 1977) |
| "No other short-course oral treatment for onchocerciasis has been demonstrated to have macrofilaricidal activity." | 3.30 | A randomized, open-label study of the tolerability and efficacy of one or three daily doses of ivermectin plus diethylcarbamazine and albendazole (IDA) versus one dose of ivermectin plus albendazole (IA) for treatment of onchocerciasis. ( Doe, F; Dubben, B; Fetcho, N; Fischer, K; Fischer, PU; Gordor, S; Goss, CW; Gyasi, ME; Hoerauf, A; Hong, AR; Kanza, E; King, CL; Laryea, R; Lew, D; Opoku, NO; Seidu, MA; Weil, GJ, 2023) |
| " Clinical adverse reactions were recorded in four ivermectin, ten DEC and three placebo patients." | 2.66 | A double-blind comparison of the efficacy and safety of ivermectin and diethylcarbamazine in a placebo controlled study of Senegalese patients with onchocerciasis. ( Aziz, MA; Badiane, S; Diallo, JS; Diallo, S; Diop-Mar, I; Gaxotte, P; Lariviere, M; N'Dir, O; Py, D; Schulz-Key, H, 1986) |
| "Previous work on monkeys and on human volunteers led to the development of a schedule of diethylcarbamazine dosage suitable for the chemoprophylaxis of loiasis." | 2.63 | Experiments on the chemoprophylaxis of Onchocerca volvulus infection. ( Duke, BO, 1968) |
| " As part of an effort to stimulate the discovery and development of new macrofilaricides, particularly for onchocerciasis, research has recently been devoted to the development of new formulations that would afford high oral bioavailability of FBZ, paving the way for potential clinical development of this repurposed drug for the treatment of human filariases." | 2.61 | Flubendazole as a macrofilaricide: History and background. ( Geary, TG; Mackenzie, CD; Silber, SA, 2019) |
| "Despite this, onchocerciasis is still prevalent in the region due to existing and emerging contextual challenges." | 1.62 | Eliminating onchocerciasis within the Meme River Basin of Cameroon: A social-ecological approach to understanding everyday realities and health systems. ( Dean, L; Dum-Buo, N; Fung, EG; Nji, TM; Ozano, K; Piotrowski, H; Theobald, S; Thomson, R; Wanji, S, 2021) |
| "Onchocerciasis and lymphatic filariasis (LF) are major filarial infections targeted for elimination in most endemic sub-Saharan Africa (SSA) countries by 2020/2025." | 1.48 | Identifying co-endemic areas for major filarial infections in sub-Saharan Africa: seeking synergies and preventing severe adverse events during mass drug administration campaigns. ( Basáñez, MG; Cano, J; O'Hanlon, SJ; Pullan, RL; Rebollo, MP; Tekle, AH; Wanji, S; Zouré, HG, 2018) |
| "The limb oedema was always located to one arm." | 1.30 | [Apropos of 5 new cases of onchocerciasis edema]. ( Bricaire, F; Caumes, E; Danis, M; Datry, A; Gentilini, M; Nozais, JP, 1997) |
| "Adverse reactions following treatment of onchocerciasis and bancroftian filariasis are common and frequently severe." | 1.29 | Interleukin-6 and tumor necrosis factor in the pathogenesis of adverse reactions after treatment of lymphatic filariasis and onchocerciasis. ( Awadzi, K; Clark, IA; Francis, H; Ottesen, EA; Rockett, KA; Turner, PF, 1994) |
| "The pathogenesis and treatment of onchocerciasis are discussed." | 1.27 | Ocular onchocerciasis with living microfilariae in the anterior chamber in two Dutch boys. ( Koppert, HC, 1983) |
| "Treatment with levamisole had a similar effect on embryogenesis, however it was much less marked." | 1.27 | The effects of diethylcarbamazine, mebendazole and levamisole on Onchocerca volvulus in vivo and in vitro. ( Gomez-Rojo, E; Greene, BM; Mackenzie, CD; Rivas-Alcala, R; Taylor, HR, 1984) |
| "Hypotension, fever, adenitis and pruritus were all correlated with infection intensity in these patients while arthralgia and tachycardia were not." | 1.27 | The Mazzotti reaction following treatment of onchocerciasis with diethylcarbamazine: clinical severity as a function of infection intensity. ( Awadzi, K; Francis, H; Ottesen, EA, 1985) |
| "Retreatment with diethylcarbamazine again caused pruritus, but this was tolerated as were subsequent treatments." | 1.26 | Subcutaneous nodules as a manifestation of onchocerciasis. A rare condition in the United States. ( Beaver, PC; Bray, DM; Grannis, FW; Palomar, JM, 1976) |
| "In our population filariasis is mainly imported from central and western Africa, especially Cameroon." | 1.26 | [Filariasis in patients returned from the tropics. Studies on 64 cases]. ( Degrémont, A; Stürchler, D, 1976) |
| "Diethylcarbamazine was given as eye drops in varying concentrations in a half-log dilution series from 1." | 1.26 | Effects of various concentrations of diethylcarbamazine citrate applied as eye drops in ocular onchocerciasis, and the possibilities of improved therapy from continuous non-pulsed delivery. ( Anderson, J; Fuglsang, H; Jones, BR, 1978) |
| "DEC has been employed in the treatment of onchocerciasis for many years, but there have been no reports of any effects of DEC on nodules." | 1.26 | An onchocercal nodule appearing during diethylcarbamazine therapy. ( Boye, ES; Connor, DH, 1982) |
| "When diethylcarbamazine (DEC) was given after suramin, increased numbers of microfilariae appeared in the blood, urine, cerebrospinal fluid (CSF) and sputum, but the increase in the blood was less marked, and of shorter duration, than in similar patients receiving DEC without previous suramin." | 1.26 | The populatin dynamics of Onchocerca volvulus microfilariae during treatment with suramin and diethylcarbamazine. ( Duke, BO; Moore, PJ; Vincelette, J, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 196 (85.96) | 18.7374 |
| 1990's | 18 (7.89) | 18.2507 |
| 2000's | 4 (1.75) | 29.6817 |
| 2010's | 8 (3.51) | 24.3611 |
| 2020's | 2 (0.88) | 2.80 |
| Authors | Studies |
|---|---|
| Opoku, NO | 2 |
| Doe, F | 1 |
| Dubben, B | 1 |
| Fetcho, N | 1 |
| Fischer, K | 1 |
| Fischer, PU | 2 |
| Gordor, S | 1 |
| Goss, CW | 1 |
| Gyasi, ME | 1 |
| Hoerauf, A | 2 |
| Hong, AR | 1 |
| Kanza, E | 1 |
| King, CL | 2 |
| Laryea, R | 1 |
| Lew, D | 1 |
| Seidu, MA | 1 |
| Weil, GJ | 3 |
| Nji, TM | 1 |
| Piotrowski, H | 1 |
| Dum-Buo, N | 1 |
| Fung, EG | 1 |
| Dean, L | 1 |
| Theobald, S | 1 |
| Thomson, R | 1 |
| Wanji, S | 2 |
| Ozano, K | 1 |
| Cano, J | 1 |
| Basáñez, MG | 1 |
| O'Hanlon, SJ | 1 |
| Tekle, AH | 1 |
| Zouré, HG | 1 |
| Rebollo, MP | 1 |
| Pullan, RL | 1 |
| Geary, TG | 2 |
| Mackenzie, CD | 6 |
| Silber, SA | 1 |
| Bulman, CA | 1 |
| Bidlow, CM | 1 |
| Lustigman, S | 1 |
| Cho-Ngwa, F | 1 |
| Williams, D | 1 |
| Rascón, AA | 1 |
| Tricoche, N | 1 |
| Samje, M | 1 |
| Bell, A | 1 |
| Suzuki, B | 1 |
| Lim, KC | 1 |
| Supakorndej, N | 1 |
| Supakorndej, P | 1 |
| Wolfe, AR | 1 |
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| Wilson, C | 1 |
| Ang, KH | 1 |
| Arkin, M | 1 |
| Gut, J | 1 |
| Franklin, C | 1 |
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| Debnath, A | 1 |
| Sakanari, JA | 1 |
| Awadzi, K | 21 |
| Attah, SK | 1 |
| Lazdins-Helds, JK | 1 |
| Kuesel, AC | 1 |
| Jacobson, JA | 1 |
| Taylor, MJ | 2 |
| Bockarie, M | 1 |
| Boatin, BA | 3 |
| Toé, L | 3 |
| Alley, ES | 2 |
| Nagelkerke, NJ | 1 |
| Borsboom, G | 1 |
| Habbema, JD | 1 |
| BAEZ, MM | 1 |
| TELLO DE LA PENA, R | 1 |
| MARTINEZ BAEZ, M | 1 |
| PIERS, F | 1 |
| ADAMS, JC | 1 |
| WOODRUFF, AW | 1 |
| BAYLET, R | 1 |
| RUIZ REYES, F | 4 |
| MAZZOTTI, L | 2 |
| IKEJIANI, O | 3 |
| MORALES CISNEROS, A | 1 |
| HUTTON, PW | 1 |
| CHARTERS, JC | 1 |
| DUKE, BO | 13 |
| MARKELL, EK | 2 |
| TURNER, J | 1 |
| FERGUSSON, AG | 1 |
| LOGAN, JC | 1 |
| VARGAS, L | 1 |
| TOVAR, J | 1 |
| MONEY, GL | 1 |
| JOHN, J | 1 |
| SEIDLER, L | 1 |
| SMIT, AM | 2 |
| FIGUEROA, LN | 2 |
| GARCIAMANZO, GA | 1 |
| BERNHARD, JA | 1 |
| SHRAND, H | 1 |
| NNOCHIRI, E | 1 |
| GORDON, RD | 1 |
| SANDARS, DF | 1 |
| SCHNEIDER, J | 1 |
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| ANDERSON, J | 15 |
| BURCH, TA | 2 |
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| HAWKING, F | 3 |
| Ozoh, G | 1 |
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| Kombila, M | 1 |
| Mbina, JR | 1 |
| Enyong, P | 1 |
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| Greene, BM | 11 |
| Taylor, HR | 17 |
| Humphrey, RL | 2 |
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| Mate, A | 1 |
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| Titanji, V | 1 |
| Langham, ME | 7 |
| Rivas-Alcalá, AR | 2 |
| Domíguez-Vázquez, A | 1 |
| Ruvalcaba-Macías, AM | 2 |
| Lugo-Pfeiffer, C | 1 |
| Beltrán, F | 1 |
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| Murphy, RP | 3 |
| Beltran-Hernandez, F | 1 |
| Titanji, VP | 1 |
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| Dadzie, KY | 4 |
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| Gilles, HM | 11 |
| Aziz, MA | 6 |
| Sanguigni, S | 1 |
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| Albiez, EJ | 5 |
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| Ross, M | 1 |
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| Kremer, M | 1 |
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| Thylefors, B | 5 |
| Orme, ML | 5 |
| Breckenridge, AM | 6 |
| Brown, EJ | 1 |
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| Somorin, AO | 1 |
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| Zielke, E | 1 |
| de Stahl, EM | 1 |
| Beltranena, F | 2 |
| Guderian, RH | 1 |
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| Corral, F | 1 |
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| Jones, BR | 2 |
| Stürchler, D | 1 |
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| Rougemont, A | 2 |
| Mattei, X | 1 |
| Discamps, C | 1 |
| Loreal, E | 1 |
| Zander, N | 2 |
| Mazelet, JR | 1 |
| Zuidema, PJ | 3 |
| Henson, PM | 1 |
| Spector, WG | 1 |
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| Bell, D | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety and Efficacy of Novel Combination Regimens for Treatment of Onchocerciasis[NCT06070116] | Phase 2 | 300 participants (Anticipated) | Interventional | 2024-01-15 | Not yet recruiting | ||
| Safety and Efficacy of Combination Therapy With Ivermectin, Diethylcarbamazine, and Albendazole (IDA) for Individuals With Onchocerciasis[NCT04188301] | Phase 2 | 154 participants (Actual) | Interventional | 2019-12-06 | Completed | ||
| Microfilarial Clearance From the Eye and Ocular Changes Associated With Ivermectin Treatment in Individuals With Onchocerciasis[NCT03517462] | 231 participants (Actual) | Interventional | 2018-08-06 | Completed | |||
| When is it Appropriate to Stop? Applied Field Research to Develop an M&E Strategy to[NCT04124250] | 10,500 participants (Anticipated) | Observational | 2019-09-17 | Recruiting | |||
| Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Single Dose Treatment With Diethylcarbamazine, Albendazole and Ivermectin in Humans With and Without Wuchereria Bancrofti Infection in Côte d'Ivoire[NCT02845713] | Phase 1 | 66 participants (Actual) | Interventional | 2016-04-17 | Completed | ||
| Effect of Albendazole Dose and Interval on Brugia Malayi Microfilarial Clearance in India: A Randomized, Open Label Study[NCT00511004] | Phase 2 | 40 participants (Actual) | Interventional | 2007-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The effectiveness of three treatment regimens for killing adult female O. volvulus worms based on the percentage of all adult female worms in nodules that are alive 18 months after treatment. (NCT04188301)
Timeframe: 18 months following treatment
| Intervention | Female worms in nodule (Count of Units) |
|---|---|
| IVM + ALB | 127 |
| IDA x 1 Dose | 142 |
| IDA x 3 Doses | 159 |
The effect of three treatment regimens for killing adult female O. volvulus worms will be compared based on the percentage of all adult female worms in nodules that are alive with embryos in the uterus 18 months after treatment. (NCT04188301)
Timeframe: 18 months following treatment.
| Intervention | Female worms in nodules (Count of Units) |
|---|---|
| IVM + ALB | 127 |
| IDA x 1 Dose | 142 |
| IDA x 3 Doses | 159 |
The effect of three treatment regimens for sterilizing adult female O. volvulus worms will be compared based on the percentage of all adult female worms that are fertile in the nodules 18 months after treatment. (NCT04188301)
Timeframe: 18 months following treatment.
| Intervention | Female worms with intact uterus (Count of Units) |
|---|---|
| IVM + ALB | 41 |
| IDA x 1 Dose | 40 |
| IDA x 3 Doses | 34 |
Rates of ocular adverse events of any grade within 3 months will be compared by treatment group. (NCT04188301)
Timeframe: within 3 months of treatment with IDA
| Intervention | Participants (Count of Participants) |
|---|---|
| IVM + ALB | 4 |
| IDA x 1 Dose | 4 |
| IDA x 3 Doses | 3 |
Rates of adverse events grade 3 or higher that occur within 7 days of treatment in the subset of participants who have intraocular microfilariae just prior to treatment with IDA will be compared by treatment group. (NCT04188301)
Timeframe: within 7 days following end of treatment
| Intervention | Participants (Count of Participants) |
|---|---|
| IVM + ALB | 0 |
| IDA x 1 Dose | 0 |
| IDA x 3 Doses | 0 |
Rates of severe adverse events (grade 3 or higher) following 1-day or 3-day triple drug treatment will be compared against those of the comparator regimen of 1 day of IVM/ALB. (NCT04188301)
Timeframe: Within 7 days following end of treatment
| Intervention | Participants (Count of Participants) |
|---|---|
| IVM + ALB | 0 |
| IDA x 1 Dose | 0 |
| IDA x 3 Doses | 0 |
The effectiveness of three treatment regimens for preventing reappearance of microfilariae in the skin as determined by skin snips at 12 and 18 months after treatment will be compared by treatment arm. Measured by the presence of microfilariae in skin snips. (NCT04188301)
Timeframe: Baseline, 12 months, and 18 months following treatment
| Intervention | Count of microfilarae+ participants (Number) | ||
|---|---|---|---|
| Baseline | Month 12 | Month 18 | |
| IDA x 1 Dose | 6 | 21 | 15 |
| IDA x 3 Doses | 0 | 21 | 17 |
| IVM + ALB | 7 | 23 | 20 |
The effectiveness of three treatment regimens for complete clearance of microfilariae from the skin as determined by skin snips at 3, 12, and 18 months after treatment with IDA will be compared by treatment arm. (NCT04188301)
Timeframe: Baseline, 3 months, 12 months, & 18 months following treatment.
| Intervention | Count of Skin Microfilaria (Geometric Mean) | |||
|---|---|---|---|---|
| Baseline | Month 3 | Month 12 | Month 18 | |
| IDA x 1 Dose | 1.7 | 3 | 2.5 | 9.0 |
| IDA x 3 Doses | NA | 2.1 | 4.7 | 8.6 |
| IVM + ALB | 3.1 | 1.9 | 4.9 | 7.0 |
Doppler detected worm nests at 2 years (NCT00511004)
Timeframe: 2 years from the time enrolled.
| Intervention | Number of nests (Median) |
|---|---|
| Standard Therapy Annual DEC/ALB | 0 |
| High Dose Annual DEC/ALB | 0 |
| High Dose Semiannual DEC/ALB | 0 |
IgG4 antibodies directed against Brugia malayi antigen (NCT00511004)
Timeframe: 2 years
| Intervention | ng/ml (Median) |
|---|---|
| Standard Therapy Annual DEC/ALB | 150 |
| High Dose Annual DEC/ALB | 224 |
| High Dose Semiannual DEC/ALB | 128 |
Night time microfilarial counts at 1 year (NCT00511004)
Timeframe: 1 year from time enrolled
| Intervention | MF/ML (Median) |
|---|---|
| Standard Therapy Annual DEC/ALB | 0 |
| High Dose Annual DEC/ALB | 0 |
| High Dose Semiannual DEC/ALB | 0 |
Night time microfilarial levels at 2 years (NCT00511004)
Timeframe: 2 years from time enrolled
| Intervention | MF/ML (Median) |
|---|---|
| Diethylcarbamazine/Albendazole -STD | 0 |
| Diethylcarbamazine/Albendazole- HD1 | 0 |
| Diethylcarbamazine/Albendazole-HD2 | 0 |
14 reviews available for diethylcarbamazine and Onchocerciasis
| Article | Year |
|---|---|
Flubendazole as a macrofilaricide: History and background.
Topics: Albendazole; Animals; Diethylcarbamazine; Elephantiasis, Filarial; Filaricides; Gastrointestinal Dis | 2019 |
Lymphatic filariasis and onchocerciasis.
Topics: Africa South of the Sahara; Age Factors; Albendazole; Animals; Anti-Bacterial Agents; Antinematodal | 2010 |
Recent advances in the epidemiology and control of filarial infections including entomological aspects of transmission.
Topics: Animals; Diethylcarbamazine; Epidemiologic Methods; Filariasis; Humans; Insect Vectors; Lymphatic Di | 1984 |
Recent advances in research on filariasis. Chemotherapy.
Topics: Animals; Anti-Inflammatory Agents; Arsenicals; Benzimidazoles; Diethylcarbamazine; Drug Evaluation, | 1984 |
[Short review of pathophysiology and therapeutic possibilities in onchocerciasis with reference to a case report].
Topics: Adult; Animals; Antibodies, Helminth; Diethylcarbamazine; Drug Therapy, Combination; Eosinophilia; H | 1994 |
Diagnostics in onchocerciasis: future challenges.
Topics: Animals; Antigens, Helminth; Diethylcarbamazine; Filaricides; Humans; Ivermectin; Microfilariae; Onc | 1998 |
[Onchocerciasis].
Topics: Animals; Antiparasitic Agents; Diagnosis, Differential; Diethylcarbamazine; Filaricides; Humans; Ive | 1999 |
Ocular onchocerciasis.
Topics: Diethylcarbamazine; Eye; Eye Diseases; Female; Glaucoma; Humans; Iritis; Keratitis; Male; Onchocerci | 1977 |
Diethylcarbamazine in the treatment of patients with onchocerciasis.
Topics: Diethylcarbamazine; Dose-Response Relationship, Drug; Humans; Onchocerciasis | 1992 |
Diethylcarbamazine in the treatment of patients with onchocerciasis.
Topics: Diethylcarbamazine; Dose-Response Relationship, Drug; Humans; Onchocerciasis | 1992 |
Diethylcarbamazine in the treatment of patients with onchocerciasis.
Topics: Diethylcarbamazine; Dose-Response Relationship, Drug; Humans; Onchocerciasis | 1992 |
Diethylcarbamazine in the treatment of patients with onchocerciasis.
Topics: Diethylcarbamazine; Dose-Response Relationship, Drug; Humans; Onchocerciasis | 1992 |
Clinical pharmacokinetics of drugs against onchocerciasis.
Topics: Anthelmintics; Benzimidazoles; Diethylcarbamazine; Filaricides; Humans; Ivermectin; Onchocerciasis; | 1990 |
Drug treatment of onchocerciasis.
Topics: Diethylcarbamazine; Humans; Ivermectin; Levamisole; Onchocerciasis; Suramin | 1988 |
Description, mechanisms and control of reactions to treatment in the human filariases.
Topics: Animals; Anthelmintics; Diethylcarbamazine; Elephantiasis, Filarial; Filariasis; Filaricides; Humans | 1987 |
Ocular onchocerciasis in the horse.
Topics: Animals; Anterior Chamber; Austria; California; Cataract; Ciliary Body; Conjunctivitis; Diethylcarba | 1971 |
Onchocerciasis.
Topics: Africa; Animals; Anthelmintics; Artiodactyla; Blindness; Cattle; Circadian Rhythm; DDT; Diethylcarba | 1970 |
38 trials available for diethylcarbamazine and Onchocerciasis
| Article | Year |
|---|---|
A randomized, open-label study of the tolerability and efficacy of one or three daily doses of ivermectin plus diethylcarbamazine and albendazole (IDA) versus one dose of ivermectin plus albendazole (IA) for treatment of onchocerciasis.
Topics: Albendazole; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Filarial; Female; Filaric | 2023 |
Diagnosis of O. volvulus infection via skin exposure to diethylcarbamazine: clinical evaluation of a transdermal delivery technology-based patch.
Topics: Administration, Cutaneous; Adolescent; Adult; Animals; Diethylcarbamazine; Female; Filaricides; Huma | 2015 |
Detection of Onchocerca volvulus infection in low prevalence areas: a comparison of three diagnostic methods.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Biopsy; Child; Child, Preschool; Diethylcarbama | 2002 |
Proteinuria associated with diethylcarbamazine treatment of onchocerciasis.
Topics: Diethylcarbamazine; Humans; Onchocerciasis; Proteinuria | 1980 |
Controlled clinical trial of oral and topical diethylcarbamazine in treatment of onchocerciasis.
Topics: Administration, Oral; Administration, Topical; Clinical Trials as Topic; Diethylcarbamazine; Double- | 1980 |
Diethylcarbamazine citrate lotion and onchocerciasis.
Topics: Administration, Oral; Administration, Topical; Clinical Trials as Topic; Diethylcarbamazine; Double- | 1980 |
Chemotherapy of onchocerciasis: a controlled comparison of mebendazole, levamisole, and diethylcarbamazine.
Topics: Adolescent; Adult; Aged; Benzimidazoles; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind | 1981 |
Comparison of flubendazole and diethylcarbamazine in treatment of onchocerciasis.
Topics: Adolescent; Adult; Antinematodal Agents; Benzimidazoles; Child; Clinical Trials as Topic; Diethylcar | 1983 |
Ivermectin in onchocerciasis.
Topics: Adolescent; Adult; Diethylcarbamazine; Humans; Ivermectin; Lactones; Male; Middle Aged; Onchocercias | 1984 |
The chemotherapy of onchocerciasis VI. The effect of indomethacin and cyproheptadine on the Mazzotti reaction.
Topics: Adult; Clinical Trials as Topic; Cyproheptadine; Diethylcarbamazine; Double-Blind Method; Humans; Hy | 1982 |
The chemotherapy of onchocerciasis VII. The effect of prednisone on the Mazzotti reaction.
Topics: Adult; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Method; Fever; Humans; Hypotension | 1982 |
The chemotherapy of onchocerciasis IX. The effect of prednisone plus cyproheptadine on the Mazzotti reaction.
Topics: Adolescent; Adult; Clinical Trials as Topic; Cyproheptadine; Diethylcarbamazine; Double-Blind Method | 1982 |
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu | 1983 |
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu | 1983 |
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu | 1983 |
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu | 1983 |
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu | 1983 |
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu | 1983 |
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu | 1983 |
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu | 1983 |
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu | 1983 |
The chemotherapy of onchocerciasis II. Quantitation of the clinical reaction to microfilaricides.
Topics: Adolescent; Adult; Clinical Trials as Topic; Diethylcarbamazine; Dose-Response Relationship, Drug; H | 1980 |
The chemotherapy of onchocerciasis iii. A comparative study of diethylcarbamazide (DEC) and metrifonate.
Topics: Adolescent; Adult; Clinical Trials as Topic; Diethylcarbamazine; Drug Administration Schedule; Human | 1980 |
Chemotherapy of onchocerciasis: a controlled clinical trial of topical diethylcarbamazine (DEC) in Guatemala.
Topics: Administration, Topical; Adolescent; Adult; Aged; Antiparasitic Agents; Child; Clinical Trials as To | 1980 |
Ocular changes with oral and transepidermal diethylcarbamazine therapy of onchocerciasis.
Topics: Administration, Oral; Administration, Topical; Adult; Clinical Trials as Topic; Diethylcarbamazine; | 1981 |
The effect of drug treatment on the pattern of emergence of Onchocerca volvulus microfilariae from skin snips.
Topics: Animals; Anthelmintics; Diethylcarbamazine; Filaricides; Humans; Levamisole; Onchocerca; Onchocercia | 1981 |
Inflammatory reactions in onchocerciasis: a report on current knowledge and recommendations for further study.
Topics: Anti-Inflammatory Agents; Antinematodal Agents; Clinical Trials as Topic; Complement C5; Diethylcarb | 1979 |
Long-term treatment of onchocerciasis in children with low doses of diethylcarbamazine.
Topics: Child; Clinical Trials as Topic; Corneal Opacity; Diethylcarbamazine; Eye; Ghana; Humans; Long-Term | 1978 |
A transepidermal chemotherapy of onchocerciasis.
Topics: Administration, Oral; Administration, Topical; Adult; Animals; Diethylcarbamazine; Emulsions; Female | 1978 |
Onchocerciasis in Guatemala. II. Microfilariae in urine, blood, and sputum after diethylcarbamazine.
Topics: Administration, Oral; Blood; Clinical Trials as Topic; Diethylcarbamazine; Guatemala; Humans; Male; | 1975 |
[Effects of diethylcarbamazine and ivermectin on the mobilization of microfilariae of Onchocerca volvulus].
Topics: Adult; Animals; Diethylcarbamazine; Double-Blind Method; Filarioidea; Humans; Ivermectin; Mali; Micr | 1989 |
Effects of high doses of diethylcarbamazine on adult Onchocerca volvulus examined by the collagenase technique and by histology.
Topics: Animals; Diethylcarbamazine; Double-Blind Method; Female; Humans; Liberia; Male; Microbial Collagena | 1988 |
Double-blind study of ivermectin and diethylcarbamazine in African onchocerciasis patients with ocular involvement.
Topics: Adolescent; Adult; Aged; Anthelmintics; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind M | 1985 |
The effect of moderate urine alkalinisation on low dose diethylcarbamazine therapy in patients with onchocerciasis.
Topics: Adolescent; Adult; Bicarbonates; Diethylcarbamazine; Drug Therapy, Combination; Humans; Hydrogen-Ion | 1986 |
Chemotherapy of onchocerciasis with high doses of diethylcarbamazine or a single dose of ivermectin: microfilaria levels and side effects.
Topics: Adult; Animals; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-B | 1988 |
A double-blind comparison of the efficacy and safety of ivermectin and diethylcarbamazine in a placebo controlled study of Senegalese patients with onchocerciasis.
Topics: Adolescent; Adult; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Method; Eye Diseases; | 1986 |
Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine.
Topics: Adult; Anthelmintics; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Method; Eye; Eye Di | 1986 |
Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine.
Topics: Adult; Anthelmintics; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Method; Eye; Eye Di | 1986 |
Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine.
Topics: Adult; Anthelmintics; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Method; Eye; Eye Di | 1986 |
Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine.
Topics: Adult; Anthelmintics; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Method; Eye; Eye Di | 1986 |
[Senegalese experience with the efficacy of ivermectin (MK 933) in the treatment of human onchocerciasis (double-blind comparative study with diethylcarbamazine citrate) (DEC.C)].
Topics: Adolescent; Adult; Anthelmintics; Diethylcarbamazine; Filaricides; Humans; Ivermectin; Lactones; Mal | 1986 |
The chemotherapy of onchocerciasis. XI. A double-blind comparative study of ivermectin, diethylcarbamazine and placebo in human onchocerciasis in northern Ghana.
Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Meth | 1986 |
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl | 1987 |
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl | 1987 |
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl | 1987 |
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl | 1987 |
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl | 1987 |
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl | 1987 |
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl | 1987 |
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl | 1987 |
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl | 1987 |
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth | 1985 |
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth | 1985 |
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth | 1985 |
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth | 1985 |
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth | 1985 |
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth | 1985 |
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth | 1985 |
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth | 1985 |
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth | 1985 |
An ocular reaction index for use in the study of onchocerciasis.
Topics: Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Blind Method; Eye; Humans; Ivermectin; | 1985 |
Topical diethylcarbamazine in ocular onchocerciasis.
Topics: Administration, Topical; Adult; Anterior Chamber; Cameroon; Cornea; Diethylcarbamazine; Edema; Eye D | 1973 |
The effects of drugs on Onchocerca volvulus. 1. Methods of assessment, population dynamics of the parasite and the effects of diethylcarbamazine.
Topics: Adolescent; Adult; Arsenicals; Cameroon; Clinical Trials as Topic; Diethylcarbamazine; Humans; Male; | 1968 |
The intake and transmissibility of Onchocerca volvulus microfilariae by Simulium damnosum fed on patients treated with Diethylcarbamazine, suramin or Mel W.
Topics: Arsenicals; Cameroon; Carrier State; Clinical Trials as Topic; Diethylcarbamazine; Diptera; Humans; | 1968 |
Experiments on the chemoprophylaxis of Onchocerca volvulus infection.
Topics: Animals; Arsenicals; Cameroon; Clinical Trials as Topic; Diethylcarbamazine; Hominidae; Humans; Onch | 1968 |
176 other studies available for diethylcarbamazine and Onchocerciasis
| Article | Year |
|---|---|
Eliminating onchocerciasis within the Meme River Basin of Cameroon: A social-ecological approach to understanding everyday realities and health systems.
Topics: Adolescent; Adult; Anthelmintics; Cameroon; Data Collection; Diethylcarbamazine; Disease Eradication | 2021 |
Global programme to eliminate lymphatic filariasis: progress report, 2016.
Topics: Albendazole; Anthelmintics; Diethylcarbamazine; Disease Eradication; Drug Therapy, Combination; Elep | 2017 |
Identifying co-endemic areas for major filarial infections in sub-Saharan Africa: seeking synergies and preventing severe adverse events during mass drug administration campaigns.
Topics: Africa South of the Sahara; Albendazole; Animals; Diethylcarbamazine; Drug Synergism; Drug Therapy, | 2018 |
Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis.
Topics: Adult; Albendazole; Animals; Anthelmintics; Auranofin; Brugia malayi; Cattle; Cell Line; Diethylcarb | 2015 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.
Topics: Africa; Albendazole; Anthelmintics; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Fi | 2017 |
Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Anthelmintics; beta-Cyclodextrins; Brugia; Chemistry, Ph | 2011 |
[Changes in eosinophilia of onchocercoses after administration of hetrazan].
Topics: Diethylcarbamazine; Eosinophilia; Leukocyte Disorders; Onchocerciasis | 1952 |
[Effect of hetrazan on Onchocerca volvulus in adult stage].
Topics: Adult; Animals; Diethylcarbamazine; Humans; Onchocerca volvulus; Onchocerciasis | 1952 |
Onchocerciasis with cutaneous lesions in a European.
Topics: Diethylcarbamazine; Humans; Onchocerciasis | 1953 |
Diethylcarbamazine in the treatment of onchocerciasis.
Topics: Diethylcarbamazine; Onchocerciasis | 1953 |
[Local treatment of onchocerciasis, especially by intracystic injection of notezine].
Topics: Diethylcarbamazine; Injections; Onchocerciasis; Piperazines | 1953 |
[Therapy of onchocerciasis, present use of specific drugs, suramins and diethylcarbamazine].
Topics: Diethylcarbamazine; Humans; Onchocerciasis; Suramin | 1953 |
[Disappearance of allergic reaction to hetrazan in five cases of oncocerciasis].
Topics: Diethylcarbamazine; Hypersensitivity; Immune System Diseases; Onchocerciasis | 1953 |
Studies in onchocerciasis. II. The use of hetrazan (banocide) in the treatment of African onchocerciasis.
Topics: Black People; Diethylcarbamazine; Humans; Onchocerciasis | 1954 |
[Diethylcarbamazine in onchocerciasis: notes on dosing in the treatment of camp].
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Diethylcarbamazine; Onchocerciasis | 1954 |
Severe onchocercal dermatosis responding to suramin and diethylcarbamazine: an illustrative case.
Topics: Diethylcarbamazine; Humans; Onchocerciasis; Skin Diseases; Suramin | 1954 |
Studies in onchocerciasis. III. The combined use of hetrazan and antrypol (Suramin B.P.) in the treatment of African onchocerciasis.
Topics: Black People; Diethylcarbamazine; Humans; Onchocerciasis; Suramin | 1954 |
Studies in onchocerciasis. IV. Successful treatment with hetrazan of frequent abortion in two cases of onchocerciasis.
Topics: Abortion, Induced; Abortion, Spontaneous; Diethylcarbamazine; Female; Humans; Onchocerciasis; Pregna | 1954 |
Onchocerciasis; incubation period, clinical course, and treatment at first hand.
Topics: Diethylcarbamazine; Hand; Humans; Onchocerciasis; Suramin | 1955 |
The reappearance, rate of increase and distribution of the microfilariae of Onchocerca volvulus following treatment with diethylcarbamazine.
Topics: Animals; Anthelmintics; Diethylcarbamazine; Humans; Microfilariae; Onchocerca volvulus; Onchocercias | 1957 |
Cortisone and prednisone in the suppression of allergic reactions to diethylcarbamazine treatment of onchocerciasis.
Topics: Anthelmintics; Cortisone; Diethylcarbamazine; Humans; Hypersensitivity; Onchocerciasis; Prednisone | 1957 |
Onchocerciasis: a review of five cases treated in Britain with diethylcarbamazine.
Topics: Anthelmintics; Diethylcarbamazine; Onchocerciasis; United Kingdom | 1957 |
Resistance of Onchocerca volvulus microfilariae to diethylcarbamazine.
Topics: Animals; Anthelmintics; Diethylcarbamazine; Humans; Onchocerca; Onchocerca volvulus; Onchocerciasis | 1957 |
'Hetrazan' eosinopenia in onchocerciasis. A preliminary communication.
Topics: Agranulocytosis; Anthelmintics; Communication; Diethylcarbamazine; Eosinophils; Leukocyte Count; Onc | 1960 |
[DAMAGE TO THE ORGAN OF VISION, CAUSED BY FILARIASIS].
Topics: Diethylcarbamazine; Filariasis; Humans; Onchocerciasis; Ophthalmology | 1963 |
THE EOSINOPHILIC REACTION IN HELMINTHIC INFECTIONS.
Topics: Animals; Ascariasis; Diethylcarbamazine; Eosinophilia; Helminthiasis; Humans; Nematode Infections; O | 1963 |
[TRIAMCINOLONE AS A PROPHYLACTIC IN THE SECONDARY REACTIONS PRODUCED BY HETRAZAN].
Topics: Biopsy; Central America; Diethylcarbamazine; Drug Hypersensitivity; Humans; Lymphadenitis; Onchocerc | 1963 |
VISCERAL LARVA MIGRANS. TOXOCARA CANIS INFECTION.
Topics: Animals; Ascariasis; Diagnosis, Differential; Diethylcarbamazine; Dogs; Eosinophilia; Eye Manifestat | 1964 |
OBSERVATIONS ON THE TREATMENT OF ONCHOCERCIASIS IN AN ENDEMIC AREA OF WESTERN NIGERIA.
Topics: Complement Fixation Tests; Diagnosis; Diethylcarbamazine; Drug Therapy; Eosinophils; Epidemiology; H | 1964 |
A CASE OF ONCHOCERCIASIS.
Topics: Diethylcarbamazine; Drug Therapy; Humans; Onchocerciasis; Pathology | 1964 |
FILARIAL INFECTIONS IN A CALIFORNIA CLINIC.
Topics: Acanthocheilonema; Adolescent; Ambulatory Care Facilities; Animals; Blood; California; Diagnosis; Di | 1964 |
[FILIARIASIS. CLINICAL ASPECTS--DIAGNOSIS--THERAPY].
Topics: Animals; Diagnosis; Diethylcarbamazine; Dracunculiasis; Drug Therapy; Filariasis; Humans; Loa; Oncho | 1964 |
A case of onchocerciasis in London and its treatment with hetrazan.
Topics: Diethylcarbamazine; Humans; London; Onchocerciasis | 1950 |
[Considerations on diethylcarbamazine as a prophylactic agent in ochocerciasis].
Topics: Diethylcarbamazine; Humans; Onchocerciasis; Piperazines | 1951 |
Experimental therapy of onchocerciasis with suramin and hetrazan; results of a three-year study.
Topics: Diethylcarbamazine; Onchocerciasis; Suramin; Therapies, Investigational | 1951 |
Observations on the use of hetrazan in onchocerciasis in Mexico.
Topics: Diethylcarbamazine; Mexico; Onchocerciasis | 1951 |
[Treatment of onchocerciasis with diethylcarbamazine].
Topics: Diethylcarbamazine; Onchocerciasis | 1951 |
A histological study of onchocerciasis treated with hetrazan.
Topics: Diethylcarbamazine; Onchocerciasis | 1952 |
[Diethylcarbamazine in the onchocerciasis zone of Oaxaca].
Topics: Diethylcarbamazine; Humans; Onchocerciasis; Piperazines | 1950 |
Evaluation of the diethylcarbamazine patch to evaluate onchocerciasis endemicity in Central Africa.
Topics: Cameroon; Central African Republic; Child, Preschool; Diethylcarbamazine; Drug Evaluation; Endemic D | 2007 |
Onchocerciasis in Tigray.
Topics: Adult; Aged; Animals; Child; Diethylcarbamazine; Doxycycline; Eosinophilia; Ethiopia; Eye Diseases; | 2007 |
Experimental therapy of onchocerciasis with sumarin and hetrazan.
Topics: Diethylcarbamazine; Onchocerciasis; Therapies, Investigational | 1949 |
Action of hetrazan on filariasis and onchocerciasis.
Topics: Diethylcarbamazine; Filariasis; Onchocerciasis; Piperazines | 1949 |
Trial of thiabendazole for the treatment of onchocerciasis.
Topics: Adult; Biopsy; Diethylcarbamazine; Humans; Male; Onchocerciasis; Thiabendazole | 1967 |
Proteinuria associated with diethylcarbamazine.
Topics: Diethylcarbamazine; Humans; Onchocerciasis; Proteinuria | 1980 |
Diethylcarbamazine lotion in onchocerciasis.
Topics: Administration, Topical; Diethylcarbamazine; Double-Blind Method; Humans; Onchocerciasis | 1980 |
The effects of diethylcarbamazine citrate, antihistamines and corticosteroid derivatives on skin reactivity to Onchocerca supernatants.
Topics: Adrenal Cortex Hormones; Diethylcarbamazine; Histamine H1 Antagonists; Humans; Onchocerca; Onchocerc | 1983 |
[Filariasis: clinico-therapeutic considerations on 24 cases].
Topics: Ascariasis; Diethylcarbamazine; Filariasis; Humans; Levamisole; Loiasis; Mansonelliasis; Onchocercia | 1984 |
Onchocerciasis in expatriates on the Ivory Coast.
Topics: Adult; Biopsy; Cote d'Ivoire; Diethylcarbamazine; Diptera; Humans; Male; Middle Aged; Onchocerciasis | 1981 |
Recent developments in the treatment of onchocerciasis.
Topics: Antiprotozoal Agents; Benzimidazoles; Diethylcarbamazine; Humans; Ivermectin; Lactones; Onchocercias | 1984 |
Deposition of eosinophil granule major basic protein onto microfilariae of Onchocerca volvulus in the skin of patients treated with diethylcarbamazine.
Topics: Adult; Animals; Blood Proteins; Child; Diethylcarbamazine; Eosinophil Granule Proteins; Eosinophilic | 1984 |
[Onchocerciasis].
Topics: Animals; Diethylcarbamazine; Female; Humans; Male; Microfilariae; Onchocerciasis; Suramin | 1984 |
Aqueous humor and serum IgE antibody in experimental ocular Onchocerca infection of guinea pigs.
Topics: Animals; Aqueous Humor; Diethylcarbamazine; Disease Models, Animal; Eye Diseases; Guinea Pigs; Immun | 1983 |
Long-term treatment of onchocerciasis patients from the Liberian rain-forest with low doses of diethylcarbamazine citrate after complete nodulectomy.
Topics: Adolescent; Adult; Animals; Combined Modality Therapy; Diethylcarbamazine; Drug Evaluation; Female; | 1983 |
A diagnostic "patch test" for onchocerciasis using topical diethylcarbamazine.
Topics: Administration, Topical; Adolescent; Adult; Child; Diethylcarbamazine; Female; Humans; Male; Middle | 1984 |
The effects of diethylcarbamazine, mebendazole and levamisole on Onchocerca volvulus in vivo and in vitro.
Topics: Animals; Benzimidazoles; Culture Media; Diethylcarbamazine; Humans; Levamisole; Male; Mebendazole; M | 1984 |
[A clinical case of ocular onchocerciasis: clinical, angiofluorographic and developmental aspects].
Topics: Adult; Chorioretinitis; Choroid; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; | 1984 |
Immunoglobulin levels in tears and aqueous humor of horses before and after diethylcarbamazine (DEC) therapy.
Topics: Animals; Aqueous Humor; Diethylcarbamazine; Horse Diseases; Horses; Immunoglobulin A; Immunoglobulin | 1984 |
Onchocerca gibsoni: increase of circulating egg antigen with chemotherapy in bovines.
Topics: Animals; Anthelmintics; Antibodies, Monoclonal; Antigens, Surface; Cattle; Diethylcarbamazine; Femal | 1984 |
Eye screening in 2234 Sierra Leonean school students and detection of onchocerciasis.
Topics: Adolescent; Child; Diethylcarbamazine; Eye Diseases; Female; Humans; Male; Mass Screening; Onchocerc | 1983 |
Ocular onchocerciasis with living microfilariae in the anterior chamber in two Dutch boys.
Topics: Adolescent; Anterior Chamber; Cameroon; Child; Child, Preschool; Diethylcarbamazine; Eye Diseases; H | 1983 |
Immunopathologic aspects in human onchocercal lymphadenitis.
Topics: Diethylcarbamazine; Humans; Immunoglobulin E; Immunoglobulin G; Lymph Nodes; Lymphadenitis; Onchocer | 1983 |
Onchocerciasis in Israel.
Topics: Adolescent; Diagnosis, Differential; Diethylcarbamazine; Ethiopia; Eye Diseases; Humans; Israel; Mal | 1984 |
Ocular immunopathologic findings of experimental onchocerciasis.
Topics: Animals; Diethylcarbamazine; Guinea Pigs; Keratitis; Leukocytes; Onchocerciasis | 1984 |
[Ocular oncocerciasis and its treatment].
Topics: Adolescent; Adult; Child; Child, Preschool; Diethylcarbamazine; Eye Diseases; Female; Humans; Male; | 1984 |
The six diseases of WHO. Onchocerciasis.
Topics: Adult; Africa, Western; Diethylcarbamazine; Humans; Insect Control; Insect Vectors; Onchocerciasis; | 1981 |
Onchocerciasis.
Topics: Adolescent; Adult; Diethylcarbamazine; Female; Humans; Insect Vectors; Male; Nigeria; Onchocerciasis | 1983 |
Studies on Bancroftian filariasis in Liberia, West Africa. IV. Notes on side effects observed during a diethylcarbamazine treatment campaign in a rural area endemic for Wuchereria bancrofti and Onchocerca volvulus.
Topics: Adolescent; Adult; Child; Child, Preschool; Diethylcarbamazine; Female; Filariasis; Humans; Liberia; | 1980 |
Management of onchocerciasis. Personal observations.
Topics: Conjunctivitis; Diethylcarbamazine; Humans; Lung Diseases, Parasitic; Lymphatic Diseases; Onchocerci | 1982 |
Report on a focus of onchocerciasis in Esmeraldas province of Ecuador.
Topics: Adult; Asian People; Biopsy; Black People; Child; Diethylcarbamazine; Ecuador; Female; Humans; India | 1982 |
Equine ocular onchocerciasis: histopathologic study.
Topics: Age Factors; Animals; Diethylcarbamazine; Disease Models, Animal; Eye Diseases; Horse Diseases; Hors | 1982 |
An onchocercal nodule appearing during diethylcarbamazine therapy.
Topics: Adult; Animals; Dermatitis; Diethylcarbamazine; Humans; Male; Microfilariae; Onchocerciasis | 1982 |
Leprosy, onchocerciasis, diethylcarbamazine and the Mazzotti reaction.
Topics: Diethylcarbamazine; Humans; Leprosy; Male; Middle Aged; Onchocerciasis | 1982 |
Ultrastructural evidence for eosinophil-parasite adherence (EPA) reaction in human onchocercal lymphadenitis in the early period following diethylcarbamazine treatment.
Topics: Diethylcarbamazine; Eosinophils; Humans; Lymph Nodes; Lymphadenitis; Microfilariae; Onchocerca; Onch | 1982 |
Prevalence of onchocerciasis in Ile-Ire District, (Ifelodun), Kwara State, Nigeria.
Topics: Adolescent; Adult; Aged; Blindness; Child; Child, Preschool; Diethylcarbamazine; Female; Humans; Inf | 1982 |
Basis for treatment and prevention of ocular onchocerciasis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Child, Preschool; Diethylcarbamazine; Drug Therap | 1982 |
[Basis of the treatment and prevention of ocular onchocerciasis].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Africa; Antinematodal Agents; Diethylcarbamazine; Drug T | 1982 |
Onchocerciasis--chemotherapy: a risk-approach.
Topics: Animals; Diethylcarbamazine; Humans; Insect Vectors; Onchocerciasis; Pest Control; Prognosis; Public | 1981 |
Diethylcarbamazine disposition in patients with onchocerciasis.
Topics: Adult; Biotransformation; Diethylcarbamazine; Humans; Kidney; Kinetics; Male; Middle Aged; Onchocerc | 1981 |
Onchocerciasis diagnosis and the probability of visual loss in patients with skin snips negative for Onchocerca volvulus microfilariae.
Topics: Adolescent; Adult; Blindness; Child; Child, Preschool; Dermatitis; Diethylcarbamazine; Humans; Oncho | 1981 |
The 'in vitro' effect of diethylcarbamazine on the motility and survival of Onchocerca volvulus microfilariae.
Topics: Animals; Diethylcarbamazine; Dose-Response Relationship, Drug; Humans; Microfilariae; Movement; Onch | 1980 |
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M | 1980 |
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M | 1980 |
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M | 1980 |
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M | 1980 |
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M | 1980 |
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M | 1980 |
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M | 1980 |
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M | 1980 |
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M | 1980 |
[River blindness, infection by the filaria Onchocerca volvulus].
Topics: Africa; Bone Diseases; Central America; Dermatitis; Diethylcarbamazine; Disease Outbreaks; Eye Disea | 1980 |
[Onchocercosis: A disease full of puzzles (author's transl)].
Topics: Diethylcarbamazine; Eye Diseases; Humans; Onchocerca; Onchocerciasis | 1980 |
Evaluation of alternate methods of rapid assessment of endemicity of Onchocerca volvulus in communities in southern Cameroon.
Topics: Adult; Animals; Cameroon; Diethylcarbamazine; Humans; Male; Middle Aged; Onchocerca volvulus; Onchoc | 1995 |
Onchocerca volvulus: parasitologic and serologic responses in experimentally infected chimpanzees and mangabey monkeys.
Topics: Animals; Antibodies, Helminth; Cercocebus; Diethylcarbamazine; Disease Models, Animal; Magnetic Reso | 1995 |
Interleukin-6 and tumor necrosis factor in the pathogenesis of adverse reactions after treatment of lymphatic filariasis and onchocerciasis.
Topics: Adult; Animals; Diethylcarbamazine; Elephantiasis, Filarial; Humans; Interleukin-6; Male; Onchocerca | 1994 |
[Secondary effects of the treatment of hypermicrofilaremic loiasis using ivermectin].
Topics: Adult; Aged; Animals; Arthralgia; C-Reactive Protein; Cameroon; Diethylcarbamazine; Female; Fever; F | 1995 |
Elevations in granulocyte-macrophage colony-stimulating factor and interleukin-5 levels precede posttreatment eosinophilia in onchocerciasis.
Topics: Antibodies, Monoclonal; Cell Survival; Cells, Cultured; Diethylcarbamazine; Eosinophilia; Eosinophil | 1996 |
Neutrophil granule proteins: evidence for the participation in the host reaction to skin microfilariae of Onchocerca volvulus after diethylcarbamazine administration.
Topics: Animals; Diethylcarbamazine; Filaricides; Humans; Neutrophils; Onchocerca volvulus; Onchocerciasis; | 1996 |
[Apropos of 5 new cases of onchocerciasis edema].
Topics: Animals; Arm; Cameroon; Cote d'Ivoire; Diethylcarbamazine; Edema; Eosinophilia; Fluorescent Antibody | 1997 |
Eotaxin expression in Onchocerca volvulus-induced dermatitis after topical application of diethylcarbamazine.
Topics: Administration, Topical; Adolescent; Animals; Antiparasitic Agents; Chemokine CCL11; Chemokines, CC; | 1999 |
Evolution of a disease.
Topics: Animals; Diethylcarbamazine; Filaricides; Guatemala; History, 20th Century; Humans; Insect Vectors; | 1999 |
Bacterial endosymbionts of Onchocerca volvulus in the pathogenesis of posttreatment reactions.
Topics: Adolescent; Adult; Calcium-Binding Proteins; Calgranulin B; Diethylcarbamazine; DNA, Bacterial; Fila | 2002 |
Adverse reactions to cutaneous diethylcarbamazine in onchocerciasis.
Topics: Diethylcarbamazine; Drug Hypersensitivity; Humans; Onchocerciasis; Pruritus | 1979 |
Visual loss during oral diethylcarbamazine treatment for onchocerciasis.
Topics: Diethylcarbamazine; Humans; Male; Onchocerciasis; Sudan; Vision Disorders; Visual Acuity; Visual Fie | 1979 |
[Filariasis in patients returned from the tropics. Studies on 64 cases].
Topics: Adult; Africa, Western; Diethylcarbamazine; Drug Eruptions; Eosinophilia; Female; Filariasis; Humans | 1976 |
[Ultrastructural aspects of the degeneration of the dermal microfilaria O. volvulus under the effect of diethylcarbamazine in human onchocerciasis].
Topics: Adolescent; Adult; Animals; Diethylcarbamazine; Female; Humans; Male; Middle Aged; Onchocerca; Oncho | 1978 |
[Filaria infections from West and Central Africa].
Topics: Adult; Africa, Central; Africa, Western; Blood; Diethylcarbamazine; Dipetalonema; Dipetalonema Infec | 1977 |
Ocular onchocerciasis.
Topics: Diethylcarbamazine; Drug Therapy, Combination; Eye Diseases; Humans; Insect Control; Onchocerciasis; | 1978 |
Treatment of onchocerciasis.
Topics: Diethylcarbamazine; Drug Administration Schedule; Humans; Onchocerciasis; Trichlorfon | 1979 |
Onchocerciasis focus in Colombia: follow-up study after 12 years.
Topics: Adolescent; Adult; Aged; Biopsy; Colombia; Diethylcarbamazine; Female; Humans; Male; Microfilariae; | 1979 |
Effect of diethylcarbamazine on the concentration of Onchocerca volvulus microfilariae in hydrocoele fluid and urine.
Topics: Adult; Animals; Diethylcarbamazine; Humans; Male; Microfilariae; Middle Aged; Onchocerca; Onchocerci | 1979 |
An evaluation of the bovine -- Onchocerca gibsoni, Onchocerca gutturosa model as a tertiary screen for drugs against Onchocerca volvulus in man.
Topics: Animals; Cattle; Diethylcarbamazine; Disease Models, Animal; Drug Therapy, Combination; Filaricides; | 1979 |
[Therapy of ocular onchocerciasis].
Topics: Anthelmintics; Diethylcarbamazine; Eye Diseases; Filaricides; Humans; Keratitis; Onchocerciasis; Sur | 1979 |
Onchocerciasis treated with diethylcarbamazine.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Diethylcarbamazine; Female; Humans; Male; Middle A | 1977 |
Effects of various concentrations of diethylcarbamazine citrate applied as eye drops in ocular onchocerciasis, and the possibilities of improved therapy from continuous non-pulsed delivery.
Topics: Adult; Child; Cornea; Diethylcarbamazine; Dose-Response Relationship, Drug; Drug Administration Sche | 1978 |
Further observations on the relationship between ocular onchocerciasis and the head nodule, and on the possible benefit of nodulectomy.
Topics: Cameroon; Dermatologic Surgical Procedures; Diethylcarbamazine; Eye; Eye Diseases; Female; Head; Hum | 1978 |
Further observations on the relationship between ocular onchocerciasis and the head nodule, and on the possible benefit of nodulectomy.
Topics: Cameroon; Dermatologic Surgical Procedures; Diethylcarbamazine; Eye; Eye Diseases; Female; Head; Hum | 1978 |
Further observations on the relationship between ocular onchocerciasis and the head nodule, and on the possible benefit of nodulectomy.
Topics: Cameroon; Dermatologic Surgical Procedures; Diethylcarbamazine; Eye; Eye Diseases; Female; Head; Hum | 1978 |
Further observations on the relationship between ocular onchocerciasis and the head nodule, and on the possible benefit of nodulectomy.
Topics: Cameroon; Dermatologic Surgical Procedures; Diethylcarbamazine; Eye; Eye Diseases; Female; Head; Hum | 1978 |
Further studies on the treatment of ocular onchocerciasis with diethylcarbamazine and suramin.
Topics: Adolescent; Adult; Betamethasone; Child; Diethylcarbamazine; Drug Therapy, Combination; Eye Diseases | 1978 |
Onchocercal dermatitis-current concepts of pathogenesis.
Topics: Dermatitis; Diethylcarbamazine; Humans; Onchocerciasis; Skin; Skin Diseases, Parasitic | 1978 |
[Preventive measures and treatment of onchocerciasis].
Topics: Administration, Oral; Anthelmintics; Body Weight; Diethylcarbamazine; Dose-Response Relationship, Dr | 1977 |
Deseril and diethylcarbamazine in the treatment of onchocerciasis.
Topics: Diethylcarbamazine; Humans; Methysergide; Onchocerciasis | 1976 |
Onchocerciasis [proceedings].
Topics: Diethylcarbamazine; Humans; Onchocerciasis | 1977 |
Dangerous reactions to treatment of onchocerciasis with diethylcarbamazine.
Topics: Adolescent; Adult; Anaphylaxis; Blood Pressure; Complement System Proteins; Diethylcarbamazine; Eosi | 1977 |
Onchocerciasis: invasion of deep organs by Onchocerca volvulus.
Topics: Aorta, Thoracic; Aortic Diseases; Autopsy; Diethylcarbamazine; Humans; Liver; Liver Diseases, Parasi | 1977 |
Microfilariae in the cerebrospinal fluid, and neurological complications, during treatment of onchocerciasis with diethylcarbamazine.
Topics: Arachnoid; Blood-Brain Barrier; Cerebrospinal Fluid; Choroid Plexus; Diethylcarbamazine; Female; Hum | 1976 |
The populatin dynamics of Onchocerca volvulus microfilariae during treatment with suramin and diethylcarbamazine.
Topics: Anterior Chamber; Diethylcarbamazine; Humans; Liver; Liver Circulation; Onchocerca; Onchocerciasis; | 1976 |
Subcutaneous nodules as a manifestation of onchocerciasis. A rare condition in the United States.
Topics: Adult; Antiparasitic Agents; Diethylcarbamazine; Female; Humans; Onchocerciasis; Skin; Skin Diseases | 1976 |
Onchocercal dermatitis: ultrastructural studies of microfilariae and host tissues, before and after treatment with diethylcarbamazine (Hetrazan).
Topics: Adult; Diethylcarbamazine; Filarioidea; Humans; Male; Microfilariae; Microscopy, Electron; Middle Ag | 1976 |
Effects of diethylcarbamazine on ocular onchocerciasis.
Topics: Adolescent; Adult; Anterior Chamber; Child; Cornea; Diethylcarbamazine; Eye Diseases; Female; Fundus | 1976 |
[Lethal coma in the course of notezine treatment and with the presence of microfilaria of Onchocerca volvulus in the cerebrospinal fluid].
Topics: Cerebrospinal Fluid; Coma; Diethylcarbamazine; Humans; Male; Microfilariae; Middle Aged; Onchocerca; | 1976 |
[Sensitivity of the Notezine test in onchocerciasis (apropos of 25 personal cases].
Topics: Adult; Diethylcarbamazine; Female; Humans; Male; Microfilariae; Onchocerca; Onchocerciasis; Skin | 1976 |
[Attempt at a collective treatment with diethylcarbamazine in a village in the region of Bamako (Mali) where onchocerciasis is hyperendemic].
Topics: Adolescent; Adult; Aged; Child; Diethylcarbamazine; Female; Humans; Male; Mali; Middle Aged; Onchoce | 1976 |
[Onchocerciasis].
Topics: Africa; Diethylcarbamazine; Diptera; Humans; Onchocerca; Onchocerciasis; Scandinavian and Nordic Cou | 1975 |
Factors influencing the passage of Onchocerca volvulus microfilariae into the urine.
Topics: Adult; Benzothiadiazines; Blood; Circadian Rhythm; Climate; Diethylcarbamazine; Diuresis; Diuretics; | 1975 |
Letter: Onchocerciasis and streptocerciasis in patients with leprosy. Altered Mazzotti reactions.
Topics: Adult; Child; Diethylcarbamazine; Female; Humans; Leprosy; Male; Onchocerciasis; Skin Manifestations | 1975 |
Clinical and laboratory changes consequent to diethylcarbamazine in patients with onchocerciasis.
Topics: Adolescent; Adult; Child; Diethylcarbamazine; Diphenhydramine; Drug Evaluation; Eye; Female; Humans; | 1976 |
Single-blind Mazzotti test for onchocerciasis.
Topics: Diethylcarbamazine; Humans; Onchocerciasis; Single-Blind Method | 1992 |
Mazzotti test for onchocerciasis.
Topics: Diethylcarbamazine; Humans; Onchocerciasis | 1992 |
Changes in antibody profile after treatment of human onchocerciasis.
Topics: Adolescent; Adult; Animals; Antibodies, Helminth; Antigens, Helminth; Diethylcarbamazine; Humans; Im | 1990 |
Eosinophil degranulation. An immunologic determinant in the pathogenesis of the Mazzotti reaction in human onchocerciasis.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Blood Proteins; Cell Degranulation; Diethy | 1990 |
Effect of diethylcarbamazine citrate and anti-inflammatory drugs on experimental onchocercal punctate keratitis.
Topics: Animals; Anti-Inflammatory Agents; Cornea; Corneal Opacity; Corneal Stroma; Diethylcarbamazine; Fema | 1987 |
Increase in natural killer cell activity during diethylcarbamazine treatment of patients with filariasis.
Topics: Adult; Animals; Diethylcarbamazine; Elephantiasis, Filarial; Female; Filariasis; Humans; Killer Cell | 1987 |
Does dexamethasone suppress the Mazzotti reaction in patients with onchocerciasis?
Topics: Adult; Animals; Dexamethasone; Diethylcarbamazine; Eosinophils; Female; Humans; Leprosy; Male; Micro | 1988 |
A curable cause of musculoskeletal pain.
Topics: Back Pain; Diagnosis, Differential; Diethylcarbamazine; Female; Humans; Onchocerciasis | 1987 |
[Cutaneous changes induced by a dose of DEC in rodents with skin microfilaria: relevance of these phenomena for understanding the Mazzotti reaction and the pathogenesis of human onchocerciasis].
Topics: Animals; Diethylcarbamazine; Disease Models, Animal; Filariasis; Humans; Microfilariae; Onchocercias | 1987 |
The use of a topical Mazzotti test in the diagnosis of onchocerciasis.
Topics: Administration, Topical; Adolescent; Adult; Animals; Child, Preschool; Diethylcarbamazine; Humans; M | 1988 |
Onchocerca volvulus. Monoclonal anti-idiotype antibody as antigen signal for the microfilaricidal cytotoxicity of diethylcarbamazine-treated platelets.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Helminth; Antibodies, Monoclonal; Antigens, Helmint | 1988 |
Autoantibody induced by experimental Onchocerca infection. Effect of different routes of administration of microfilariae and of treatment with diethylcarbamazine citrate and ivermectin.
Topics: Animals; Antibodies, Helminth; Autoantibodies; Corneal Diseases; Diethylcarbamazine; Enzyme-Linked I | 1988 |
DEC treatment of onchocerciasis.
Topics: Diethylcarbamazine; Humans; Onchocerciasis | 1988 |
Evaluation of drugs against Onchocerca microfiliariae in an inbred mouse model.
Topics: Animals; Anthelmintics; Diethylcarbamazine; Disease Models, Animal; Drug Evaluation, Preclinical; El | 1986 |
The chemotherapy of onchocerciasis. XII. The prediction of microfilarial loads in patients with onchocerciasis after treatment with diethylcarbamazine in northern Ghana.
Topics: Adult; Age Factors; Animals; Diethylcarbamazine; Dose-Response Relationship, Drug; Humans; Microfila | 1987 |
The use of diethylcarbamazine cream in the diagnosis of onchocerciasis.
Topics: Administration, Topical; Biopsy; Diethylcarbamazine; Humans; Microfilariae; Onchocerca; Onchocercias | 1987 |
Does diethylcarbamazine have any worthwhile action against adult Onchocerca volvulus?
Topics: Animals; Diethylcarbamazine; Female; Humans; Onchocerca; Onchocerciasis | 1986 |
Need for caution in use of DEC for treatment of onchocerciasis.
Topics: Diethylcarbamazine; Eye Diseases; Humans; Onchocerciasis | 1986 |
Experimental ocular onchocerciasis in cynomolgus monkeys.
Topics: Animals; Anterior Chamber; Diethylcarbamazine; Disease Models, Animal; Eye; Eye Diseases; Macaca fas | 1986 |
[Granulomatous and eosinophilic myositis due to Onchocerca volvulus].
Topics: Adult; Diethylcarbamazine; Drug Therapy, Combination; Female; Granuloma; Humans; Microfilariae; Musc | 1985 |
The Mazzotti reaction following treatment of onchocerciasis with diethylcarbamazine: clinical severity as a function of infection intensity.
Topics: Adolescent; Adult; Arthritis; Diethylcarbamazine; Fever; Humans; Leukocyte Count; Liver; Lymphadenit | 1985 |
On the treatment of onchocerciasis in Sudan.
Topics: Diethylcarbamazine; Female; Humans; Male; Onchocerciasis; Skin Pigmentation; Sudan; Suramin | 1985 |
The Onchocerca volvulus micro- and macrofilarial responses in onchocerciasis patients to increased dosage of diethylcarbamazine.
Topics: Administration, Oral; Administration, Topical; Adult; Animals; Anterior Chamber; Cornea; Diethylcarb | 1985 |
Eosinophilic cellulitis as a manifestation of onchocerciasis.
Topics: Cellulitis; Diethylcarbamazine; Eosinophilia; Humans; Male; Middle Aged; Onchocerciasis; Skin | 1985 |
Effect of diethylcarbamazine and suramin on Onchocerca volvulus microfilariae in urine.
Topics: Adolescent; Adult; Aged; Diethylcarbamazine; Humans; Methods; Middle Aged; Onchocerca; Onchocerciasi | 1973 |
[Onchocerciasis in Mexico].
Topics: Animals; Atrophy; Chorioretinitis; Culicidae; Diethylcarbamazine; Ecology; Geography; Humans; Insect | 1974 |
[The therapeutic difficulties of ocular onchocerciasis].
Topics: Arsenicals; Diethylcarbamazine; Eye Diseases; Humans; Onchocerciasis; Optic Nerve; Suramin; Thiabend | 1969 |
Onchocerciasis. Onchocercal dermatitis, lymphadenitis, and elephantiasis in the Ubangi territory.
Topics: Adolescent; Adult; Biopsy; Body Temperature; Child; Child, Preschool; Collagen; Congo; Dermatitis; D | 1970 |
Onchocerciasis.
Topics: Adult; Africa; Animals; Blindness; Child; Colombia; Diethylcarbamazine; Diptera; Disease Vectors; Gu | 1974 |
Onchocerciasis presenting with swelling of limb.
Topics: Adult; Ankle; Biopsy; Brazil; Collagen; Diethylcarbamazine; Eosinophils; Extremities; Fluorescent An | 1974 |
Application of the indirect fluorescent antibody test on sections of adult filariae to the serodiagnosis, epidemiology and post-therapeutic surveillance of human filariasis.
Topics: Antigens; Central African Republic; Colombia; Cross Reactions; Diethylcarbamazine; Epidemiologic Met | 1974 |
[Onchocerciasis imported in the Netherlands; a review of 100 cases].
Topics: Adolescent; Adult; Cameroon; Child; Child, Preschool; Diethylcarbamazine; Female; Humans; Male; Midd | 1973 |
Onchocerciasis in Canada.
Topics: Adult; Africa, Western; Biopsy; Canada; Diethylcarbamazine; Hookworm Infections; Humans; Intestinal | 1974 |
Letter: Collapse during treatment of onchocerciasis with diethylcarbamazine.
Topics: Adolescent; Adult; Diethylcarbamazine; Humans; Male; Onchocerciasis; Respiratory Insufficiency; Shoc | 1974 |
Microfilariae of Onchocerca volvulus in blood and urine before, during, and after treatment with diethylcarbamazine.
Topics: Adolescent; Adult; Child; Diethylcarbamazine; Female; Humans; Male; Middle Aged; Onchocerca; Onchoce | 1974 |
Some observations on onchocerciasis in the Koinadugu District of Sierra Leone.
Topics: Corneal Opacity; Deafness; Diethylcarbamazine; Hernia, Inguinal; Humans; Keratitis; Male; Onchocerci | 1974 |
Chemotherapeutic studies on Litomosoides carinii infection of Mastomys natalensis. 4. The prophylactic and suppressive activity of suramin.
Topics: Animals; Diethylcarbamazine; Disease Models, Animal; Female; Humans; Injections, Intradermal; Male; | 1974 |
Effect of trichlorophone against West African forest strain of Onchocerca volvulus.
Topics: Africa, Western; Anthelmintics; Diethylcarbamazine; Humans; Onchocerciasis; Organophosphonates; Skin | 1972 |
Onchocerciasis (ocular).
Topics: Biopsy; Child; Diagnosis, Differential; Diethylcarbamazine; Diphenhydramine; Eye Diseases; Female; H | 1971 |
Immunological reactions in onchocerciasis.
Topics: Antibody Formation; Diethylcarbamazine; Humans; Onchocerciasis; Precipitin Tests; Skin Tests | 1970 |
Topical diethylcarbamazine in the treatment of ocular onchocerciasis.
Topics: Absorption; Animals; Diethylcarbamazine; Eye Diseases; Onchocerciasis; Ophthalmic Solutions; Rabbits | 1970 |
[Onchocerciasis].
Topics: Adult; Biopsy; Diethylcarbamazine; Humans; Male; Onchocerca; Onchocerciasis; Skin Manifestations | 1970 |
Topical hetrazan in the treatment of ocular onchocerciasis.
Topics: Adult; Blindness; Conjunctiva; Diethylcarbamazine; Eye Diseases; Humans; Onchocerca; Onchocerciasis | 1970 |
Onchocerciasis in the Kaffa Province of Ethiopia.
Topics: Adolescent; Adult; Child; Child, Preschool; Diethylcarbamazine; Eosinophilia; Ethiopia; Female; Huma | 1967 |
[Eye involvement in onchocerciasis].
Topics: Adult; Biopsy; Complement Fixation Tests; Cornea; Diagnosis, Differential; Diethylcarbamazine; Eye D | 1967 |
[Clinical and histological evaluation of the treatment of a clinical case of onchocerciasis with antrypol and hetrazan].
Topics: Adult; Biopsy; Diagnosis, Differential; Diethylcarbamazine; Humans; Male; Onchocerciasis; Suramin | 1967 |
Ocular penetration of hetrazan in rabbits.
Topics: Animals; Aqueous Humor; Diethylcarbamazine; Eye; Injections, Intravenous; Onchocerciasis; Ophthalmic | 1968 |
Onchocerciasis.
Topics: Africa; Central America; Diagnosis, Differential; Diethylcarbamazine; Eye Manifestations; Humans; On | 1968 |
Fatalities after treatment of onchocerciasis with diethylcarbamazine.
Topics: Diethylcarbamazine; Humans; Onchocerciasis | 1969 |