Page last updated: 2024-10-26

diethylcarbamazine and Keratitis

diethylcarbamazine has been researched along with Keratitis in 10 studies

Diethylcarbamazine: An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.

Keratitis: Inflammation of the cornea.

Research Excerpts

ExcerptRelevanceReference
"In a randomised double-blind study, ivermectin was compared with diethylcarbamazine (DEC) and placebo in the treatment of onchocerciasis in 30 male patients from Mali with moderate to heavy Onchocerca volvulus infections and ocular involvement."9.05Double-blind study of ivermectin and diethylcarbamazine in African onchocerciasis patients with ocular involvement. ( Aziz, M; Basset, D; Beauvais, B; Derouin, F; Gaxotte, P; Ginoux, J; Lariviere, M; Schulz-Key, H; Vingtain, P; Weimann, D, 1985)
"A single 10-14 day course of diethylcarbamazine (DEC) was given under betamethazone cover to 18 patients (Group A) with ocular onchocerciasis, and the effects were studied in detail over 1-2 years."7.65Effects of diethylcarbamazine on ocular onchocerciasis. ( Anderson, J; de C Marshall, TF; Fuglsang, H, 1976)
"In a randomised double-blind study, ivermectin was compared with diethylcarbamazine (DEC) and placebo in the treatment of onchocerciasis in 30 male patients from Mali with moderate to heavy Onchocerca volvulus infections and ocular involvement."5.05Double-blind study of ivermectin and diethylcarbamazine in African onchocerciasis patients with ocular involvement. ( Aziz, M; Basset, D; Beauvais, B; Derouin, F; Gaxotte, P; Ginoux, J; Lariviere, M; Schulz-Key, H; Vingtain, P; Weimann, D, 1985)
"A single 10-14 day course of diethylcarbamazine (DEC) was given under betamethazone cover to 18 patients (Group A) with ocular onchocerciasis, and the effects were studied in detail over 1-2 years."3.65Effects of diethylcarbamazine on ocular onchocerciasis. ( Anderson, J; de C Marshall, TF; Fuglsang, H, 1976)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Donnelly, JJ3
Rockey, JH3
Bianco, AE1
Soulsby, EJ1
Anderson, J2
Fuglsang, H2
Vingtain, P2
Lucot, J1
Chovet, M1
de C Marshall, TF1
Sakla, AA1
Hill, DE2
Lok, JB2
Khatami, M2
Lariviere, M1
Aziz, M1
Beauvais, B1
Weimann, D1
Derouin, F1
Ginoux, J1
Schulz-Key, H1
Gaxotte, P1
Basset, D1
Xi, MS1
Haldar, JP1
Grüntzig, J1
Tejan-Jalloh, II1
Cello, RM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Microfilarial Clearance From the Eye and Ocular Changes Associated With Ivermectin Treatment in Individuals With Onchocerciasis[NCT03517462]231 participants (Actual)Interventional2018-08-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for diethylcarbamazine and Keratitis

ArticleYear
Ocular onchocerciasis.
    Tropical diseases bulletin, 1977, Volume: 74, Issue:4

    Topics: Diethylcarbamazine; Eye; Eye Diseases; Female; Glaucoma; Humans; Iritis; Keratitis; Male; Onchocerci

1977
Ocular onchocerciasis in the horse.
    Equine veterinary journal, 1971, Volume: 3, Issue:4

    Topics: Animals; Anterior Chamber; Austria; California; Cataract; Ciliary Body; Conjunctivitis; Diethylcarba

1971

Trials

1 trial available for diethylcarbamazine and Keratitis

ArticleYear
Double-blind study of ivermectin and diethylcarbamazine in African onchocerciasis patients with ocular involvement.
    Lancet (London, England), 1985, Jul-27, Volume: 2, Issue:8448

    Topics: Adolescent; Adult; Aged; Anthelmintics; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind M

1985

Other Studies

7 other studies available for diethylcarbamazine and Keratitis

ArticleYear
Ocular immunopathologic findings of experimental onchocerciasis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:4

    Topics: Animals; Diethylcarbamazine; Guinea Pigs; Keratitis; Leukocytes; Onchocerciasis

1984
[Therapy of ocular onchocerciasis].
    Revue internationale du trachome et de pathologie oculaire tropicale et subtropicale : organe de la Ligue contre le trachome avec la collaboration de l'International Organization against Trachoma et des organisations nationales et inter..., 1979, Volume: 56, Issue:3-4

    Topics: Anthelmintics; Diethylcarbamazine; Eye Diseases; Filaricides; Humans; Keratitis; Onchocerciasis; Sur

1979
Effects of diethylcarbamazine on ocular onchocerciasis.
    Tropenmedizin und Parasitologie, 1976, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Anterior Chamber; Child; Cornea; Diethylcarbamazine; Eye Diseases; Female; Fundus

1976
Effect of diethylcarbamazine citrate and anti-inflammatory drugs on experimental onchocercal punctate keratitis.
    Ophthalmic research, 1987, Volume: 19, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Cornea; Corneal Opacity; Corneal Stroma; Diethylcarbamazine; Fema

1987
Autoantibody induced by experimental Onchocerca infection. Effect of different routes of administration of microfilariae and of treatment with diethylcarbamazine citrate and ivermectin.
    Investigative ophthalmology & visual science, 1988, Volume: 29, Issue:5

    Topics: Animals; Antibodies, Helminth; Autoantibodies; Corneal Diseases; Diethylcarbamazine; Enzyme-Linked I

1988
[Onchocerciasis in Mexico].
    Documenta ophthalmologica. Advances in ophthalmology, 1974, Apr-26, Volume: 37, Issue:1

    Topics: Animals; Atrophy; Chorioretinitis; Culicidae; Diethylcarbamazine; Ecology; Geography; Humans; Insect

1974
Some observations on onchocerciasis in the Koinadugu District of Sierra Leone.
    Tropical doctor, 1974, Volume: 4, Issue:1

    Topics: Corneal Opacity; Deafness; Diethylcarbamazine; Hernia, Inguinal; Humans; Keratitis; Male; Onchocerci

1974