diethylcarbamazine has been researched along with Hypertension, Pulmonary in 11 studies
Diethylcarbamazine: An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we investigated whether a cyclooxygenase-2 (COX-2) inhibitor or diethylcarbamazine (DEC), that is known for its 5-lipoxygenase inhibiting and antioxidant actions, modify the development of PAH in the Sugen 5416/hypoxia (SuHx) rat model." | 3.81 | Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension. ( Abbate, A; Al-Husseini, A; Chalfant, CE; Drake, JI; Farkas, L; Kraskauskas, D; Van Tassel, B; Voelkel, NF; Wijesinghe, DS, 2015) |
| "Indomethacin prevented the increase in both cyclooxygenase metabolites, but had no effect on the pulmonary hypertension." | 1.28 | Pulmonary hypertensive response to foreign body microemboli. ( Fairman, RP; Farber, HW; Glauser, FL; Millan, JE; Rounds, S, 1990) |
| "Diethylcarbamazine (DEC) is an inhibitor of lipoxygenase, with protective effects in several experimental models of anaphylaxis and lung dysfunction." | 1.27 | Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep. ( Brigham, KL; Kobayashi, T; Newman, JH; Zadoff, AD, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ribeiro, EL | 1 |
| Fragoso, IT | 1 |
| Gomes, FODS | 1 |
| Oliveira, AC | 1 |
| Silva, AKSE | 1 |
| Silva, PME | 1 |
| Ciambarella, BT | 1 |
| Ramos, IPR | 1 |
| Peixoto, CA | 1 |
| Al-Husseini, A | 1 |
| Wijesinghe, DS | 1 |
| Farkas, L | 1 |
| Kraskauskas, D | 1 |
| Drake, JI | 1 |
| Van Tassel, B | 1 |
| Abbate, A | 1 |
| Chalfant, CE | 1 |
| Voelkel, NF | 4 |
| Knight, DH | 1 |
| Davidson, D | 1 |
| Drafta, D | 1 |
| Farber, HW | 1 |
| Fairman, RP | 1 |
| Rounds, S | 1 |
| Millan, JE | 1 |
| Glauser, FL | 1 |
| Klausner, JM | 1 |
| Goldman, G | 1 |
| Skornick, Y | 1 |
| Valeri, R | 1 |
| Inbar, M | 1 |
| Shepro, D | 1 |
| Hechtman, HB | 1 |
| Burghuber, OC | 1 |
| Morganroth, ML | 3 |
| Stenmark, KR | 3 |
| Morris, KG | 2 |
| Reeves, JT | 3 |
| Zadoff, AD | 1 |
| Kobayashi, T | 1 |
| Brigham, KL | 1 |
| Newman, JH | 1 |
| Remigio, LK | 1 |
| Murphy, RC | 2 |
| Henson, PM | 1 |
| Mathias, MM | 1 |
| Mathias, M | 1 |
| Obeyesekere, I | 1 |
| Peiris, D | 1 |
1 review available for diethylcarbamazine and Hypertension, Pulmonary
| Article | Year |
|---|---|
Interleukin-2-induced lung permeability is mediated by leukotriene B4.
Topics: Animals; Blood Pressure; Body Temperature; Capillary Permeability; Diethylcarbamazine; Female; Hyper | 1990 |
10 other studies available for diethylcarbamazine and Hypertension, Pulmonary
| Article | Year |
|---|---|
Diethylcarbamazine: A potential treatment drug for pulmonary hypertension?
Topics: Actins; Animals; Apoptosis; Apoptosis Regulatory Proteins; Bone Morphogenetic Protein Receptors, Typ | 2017 |
Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arterioles; Cyclooxyg | 2015 |
Heartworm heart disease.
Topics: Aedes; Angiocardiography; Animals; Arsenamide; Auscultation; Blood; Diethylcarbamazine; Dirofilaria | 1977 |
Prolonged pulmonary hypertension caused by platelet-activating factor and leukotriene C4 in the rat lung.
Topics: Animals; Arachidonate 5-Lipoxygenase; Diethylcarbamazine; Hypertension, Pulmonary; In Vitro Techniqu | 1992 |
Pulmonary hypertensive response to foreign body microemboli.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Chromone | 1990 |
[Inhibition of hypoxic pulmonary vasoconstriction by leukotriene blockade].
Topics: Angiotensin II; Animals; Diethylcarbamazine; Dose-Response Relationship, Drug; Hypertension, Pulmona | 1986 |
Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Diethylcarbamazine; Endotoxins; Hemodynamics; Hypertension, P | 1986 |
Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Aci | 1985 |
Diethylcarbamazine inhibits acute and chronic hypoxic pulmonary hypertension in awake rats.
Topics: Acute Disease; Altitude; Animals; Blood Pressure; Body Weight; Chronic Disease; Diethylcarbamazine; | 1985 |
Pulmonary hypertension and filariasis.
Topics: Adult; Diethylcarbamazine; Eosinophilia; Epididymis; Female; Filariasis; Humans; Hypertension, Pulmo | 1974 |