Page last updated: 2024-10-26

diethylcarbamazine and Eye Disorders

diethylcarbamazine has been researched along with Eye Disorders in 53 studies

Diethylcarbamazine: An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.

Research Excerpts

ExcerptRelevanceReference
"The ocular changes that occur with diethylcarbamazine treatment of onchocerciasis seriously restrict its usefulness."9.06Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine. ( Aziz, MA; Cupp, EW; D'Anna, SA; Greene, BM; Keyvan-Larijani, E; Murphy, RP; Newland, HS; Taylor, HR; White, AT, 1986)
"In a randomised double-blind study, ivermectin was compared with diethylcarbamazine (DEC) and placebo in the treatment of onchocerciasis in 30 male patients from Mali with moderate to heavy Onchocerca volvulus infections and ocular involvement."9.05Double-blind study of ivermectin and diethylcarbamazine in African onchocerciasis patients with ocular involvement. ( Aziz, M; Basset, D; Beauvais, B; Derouin, F; Gaxotte, P; Ginoux, J; Lariviere, M; Schulz-Key, H; Vingtain, P; Weimann, D, 1985)
"We compared ivermectin with diethylcarbamazine for the treatment of onchocerciasis in a double-blind, placebo-controlled trial."9.05Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis. ( Aziz, MA; Cupp, EW; D'Anna, SA; Goldschmidt, LP; Greene, BM; Murphy, RP; Newland, HS; Schulz-Key, H; Taylor, HR; White, AT, 1985)
"The response of 45 severely infected onchocerciasis patients to relatively high doses of diethylcarbamazine citrate (DEC-C) has been determined."7.67The Onchocerca volvulus micro- and macrofilarial responses in onchocerciasis patients to increased dosage of diethylcarbamazine. ( Beltranena, F; Langham, ME, 1985)
"Eighteen patients, moderately to heavily infected with onchocerciasis, were treated with a standard course of diethylcarbamazine citrate (DEC-C)."7.66Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate. ( Anderson, J; Bird, AC; el-Sheikh, H; Fuglsang, H, 1980)
"A single 10-14 day course of diethylcarbamazine (DEC) was given under betamethazone cover to 18 patients (Group A) with ocular onchocerciasis, and the effects were studied in detail over 1-2 years."7.65Effects of diethylcarbamazine on ocular onchocerciasis. ( Anderson, J; de C Marshall, TF; Fuglsang, H, 1976)
" Clinical adverse reactions were recorded in four ivermectin, ten DEC and three placebo patients."6.66A double-blind comparison of the efficacy and safety of ivermectin and diethylcarbamazine in a placebo controlled study of Senegalese patients with onchocerciasis. ( Aziz, MA; Badiane, S; Diallo, JS; Diallo, S; Diop-Mar, I; Gaxotte, P; Lariviere, M; N'Dir, O; Py, D; Schulz-Key, H, 1986)
"Diethylcarbamazine was given as eye drops in varying concentrations in a half-log dilution series from 1."5.26Effects of various concentrations of diethylcarbamazine citrate applied as eye drops in ocular onchocerciasis, and the possibilities of improved therapy from continuous non-pulsed delivery. ( Anderson, J; Fuglsang, H; Jones, BR, 1978)
"The ocular changes that occur with diethylcarbamazine treatment of onchocerciasis seriously restrict its usefulness."5.06Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine. ( Aziz, MA; Cupp, EW; D'Anna, SA; Greene, BM; Keyvan-Larijani, E; Murphy, RP; Newland, HS; Taylor, HR; White, AT, 1986)
"In a randomised double-blind study, ivermectin was compared with diethylcarbamazine (DEC) and placebo in the treatment of onchocerciasis in 30 male patients from Mali with moderate to heavy Onchocerca volvulus infections and ocular involvement."5.05Double-blind study of ivermectin and diethylcarbamazine in African onchocerciasis patients with ocular involvement. ( Aziz, M; Basset, D; Beauvais, B; Derouin, F; Gaxotte, P; Ginoux, J; Lariviere, M; Schulz-Key, H; Vingtain, P; Weimann, D, 1985)
"We compared ivermectin with diethylcarbamazine for the treatment of onchocerciasis in a double-blind, placebo-controlled trial."5.05Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis. ( Aziz, MA; Cupp, EW; D'Anna, SA; Goldschmidt, LP; Greene, BM; Murphy, RP; Newland, HS; Schulz-Key, H; Taylor, HR; White, AT, 1985)
"The response of 45 severely infected onchocerciasis patients to relatively high doses of diethylcarbamazine citrate (DEC-C) has been determined."3.67The Onchocerca volvulus micro- and macrofilarial responses in onchocerciasis patients to increased dosage of diethylcarbamazine. ( Beltranena, F; Langham, ME, 1985)
"Eighteen patients, moderately to heavily infected with onchocerciasis, were treated with a standard course of diethylcarbamazine citrate (DEC-C)."3.66Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate. ( Anderson, J; Bird, AC; el-Sheikh, H; Fuglsang, H, 1980)
"Recurrent skin edemata due to an infestation with the filaria Loa loa are called Cameroon or Calabar swellings."3.66[Cameroon swelling; infection by the filaria Loa loa]. ( Gewalt, W; Grüntzig, J, 1979)
"A single 10-14 day course of diethylcarbamazine (DEC) was given under betamethazone cover to 18 patients (Group A) with ocular onchocerciasis, and the effects were studied in detail over 1-2 years."3.65Effects of diethylcarbamazine on ocular onchocerciasis. ( Anderson, J; de C Marshall, TF; Fuglsang, H, 1976)
" Clinical adverse reactions were recorded in four ivermectin, ten DEC and three placebo patients."2.66A double-blind comparison of the efficacy and safety of ivermectin and diethylcarbamazine in a placebo controlled study of Senegalese patients with onchocerciasis. ( Aziz, MA; Badiane, S; Diallo, JS; Diallo, S; Diop-Mar, I; Gaxotte, P; Lariviere, M; N'Dir, O; Py, D; Schulz-Key, H, 1986)
"Ocular filariasis was observed in an African student living in Missouri."1.27Loa loa: ocular filariasis in an African student in Missouri. ( Lee, BY; McMillian, R, 1984)
"The pathogenesis and treatment of onchocerciasis are discussed."1.27Ocular onchocerciasis with living microfilariae in the anterior chamber in two Dutch boys. ( Koppert, HC, 1983)
"Diethylcarbamazine was given as eye drops in varying concentrations in a half-log dilution series from 1."1.26Effects of various concentrations of diethylcarbamazine citrate applied as eye drops in ocular onchocerciasis, and the possibilities of improved therapy from continuous non-pulsed delivery. ( Anderson, J; Fuglsang, H; Jones, BR, 1978)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199050 (94.34)18.7374
1990's0 (0.00)18.2507
2000's2 (3.77)29.6817
2010's1 (1.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Senanayake, MP1
Infaq, ML1
Adikaram, SG1
Udagama, PV1
Uhlig, CE1
Dietrich, M1
Busse, H1
MAZZOTTI, L1
TORROELLA, J1
Terranova, M1
Padovese, V1
Klaus, S1
Morrone, A1
Donnelly, JJ2
Rockey, JH2
Bianco, AE1
Soulsby, EJ1
Gentilini, M1
Carme, B1
Giovannini, A1
Volanti, S1
Chillemi, P1
Lee, BY1
McMillian, R1
Stilma, JS1
Ebley, DM1
Coker, SM1
Koppert, HC1
Rozenman, D1
Kremer, M1
Zuckerman, F1
Thylefors, B5
Greene, BM5
Taylor, HR6
Brown, EJ1
Humphrey, RL1
Lawley, TJ1
Schmidt, GM1
Krehbiel, JD1
Coley, SC1
Leid, RW1
Rolland, A2
Bird, AC2
el-Sheikh, H1
Anderson, J7
Fuglsang, H7
Grüntzig, J2
Merz, M1
Renard, G1
Gewalt, W1
Vingtain, P2
Lucot, J1
Chovet, M1
Dissanaike, AS1
Ramalingam, S1
Fong, A1
Pathmayokan, S1
Thomas, V1
Kan, SP1
Sprent, JF1
Jones, HI1
Jones, BR2
de C Marshall, TF1
Lariviere, M2
Aziz, M1
Beauvais, B1
Weimann, D1
Derouin, F1
Ginoux, J1
Schulz-Key, H4
Gaxotte, P2
Basset, D1
Albiez, EJ1
Newland, HS3
White, AT3
Kaiser, A1
Büttner, DW1
Diallo, S1
Aziz, MA4
Diallo, JS1
Diop-Mar, I1
N'Dir, O1
Badiane, S1
Py, D1
Toufic, N2
Murphy, RP2
D'Anna, SA2
Keyvan-Larijani, E1
Cupp, EW2
Dadzie, KY1
Awadzi, K1
Gilles, HM1
Duke, BO1
Goldschmidt, LP1
Young, E1
Khatami, M1
Lok, JB1
Langham, ME1
Beltranena, F1
Johnson, GJ1
Axsmith, K1
Desser, SS1
Cello, RM1
Scheie, HG1
Shannon, RE1
Yanoff, M1
Lazar, M2
Lieberman, TW1
Leopold, IH2
Ben-Sira, I1
Aviel, E1
Liebermann, TW1
Tham, MH1
Hall, IB1
Gornig, H1
Valvo, A1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Efficacy of Combination Therapy With Ivermectin, Diethylcarbamazine, and Albendazole (IDA) for Individuals With Onchocerciasis[NCT04188301]Phase 2154 participants (Actual)Interventional2019-12-06Completed
Safety and Efficacy of Novel Combination Regimens for Treatment of Onchocerciasis[NCT06070116]Phase 2300 participants (Anticipated)Interventional2024-01-15Not yet recruiting
Microfilarial Clearance From the Eye and Ocular Changes Associated With Ivermectin Treatment in Individuals With Onchocerciasis[NCT03517462]231 participants (Actual)Interventional2018-08-06Completed
Effect of Albendazole Dose and Interval on Brugia Malayi Microfilarial Clearance in India: A Randomized, Open Label Study[NCT00511004]Phase 240 participants (Actual)Interventional2007-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Effectiveness of Killing Adult Female Worms

The effectiveness of three treatment regimens for killing adult female O. volvulus worms based on the percentage of all adult female worms in nodules that are alive 18 months after treatment. (NCT04188301)
Timeframe: 18 months following treatment

InterventionFemale worms in nodule (Count of Units)
IVM + ALB127
IDA x 1 Dose142
IDA x 3 Doses159

Percentage of Worms Killed Across Study Arms

The effect of three treatment regimens for killing adult female O. volvulus worms will be compared based on the percentage of all adult female worms in nodules that are alive with embryos in the uterus 18 months after treatment. (NCT04188301)
Timeframe: 18 months following treatment.

InterventionFemale worms in nodules (Count of Units)
IVM + ALB127
IDA x 1 Dose142
IDA x 3 Doses159

Percentage of Worms Sterilized Across Study Arms

The effect of three treatment regimens for sterilizing adult female O. volvulus worms will be compared based on the percentage of all adult female worms that are fertile in the nodules 18 months after treatment. (NCT04188301)
Timeframe: 18 months following treatment.

InterventionFemale worms with intact uterus (Count of Units)
IVM + ALB41
IDA x 1 Dose40
IDA x 3 Doses34

Rates of Ocular Adverse Events (Any Grade) by Treatment Group

Rates of ocular adverse events of any grade within 3 months will be compared by treatment group. (NCT04188301)
Timeframe: within 3 months of treatment with IDA

InterventionParticipants (Count of Participants)
IVM + ALB4
IDA x 1 Dose4
IDA x 3 Doses3

Rates of SAEs by Treatment Group in Those With Intraocular Microfilariae Just Prior to Treatment With IDA

Rates of adverse events grade 3 or higher that occur within 7 days of treatment in the subset of participants who have intraocular microfilariae just prior to treatment with IDA will be compared by treatment group. (NCT04188301)
Timeframe: within 7 days following end of treatment

InterventionParticipants (Count of Participants)
IVM + ALB0
IDA x 1 Dose0
IDA x 3 Doses0

Rates of Severe Adverse Events (SAEs) Across Study Arms

Rates of severe adverse events (grade 3 or higher) following 1-day or 3-day triple drug treatment will be compared against those of the comparator regimen of 1 day of IVM/ALB. (NCT04188301)
Timeframe: Within 7 days following end of treatment

InterventionParticipants (Count of Participants)
IVM + ALB0
IDA x 1 Dose0
IDA x 3 Doses0

Effectiveness for Preventing Reappearance of Microfilariae in the Skin by Skin Snips

The effectiveness of three treatment regimens for preventing reappearance of microfilariae in the skin as determined by skin snips at 12 and 18 months after treatment will be compared by treatment arm. Measured by the presence of microfilariae in skin snips. (NCT04188301)
Timeframe: Baseline, 12 months, and 18 months following treatment

,,
InterventionCount of microfilarae+ participants (Number)
BaselineMonth 12Month 18
IDA x 1 Dose62115
IDA x 3 Doses02117
IVM + ALB72320

Effectiveness of Clearing Microfilariae From Skin by Skin Snips

The effectiveness of three treatment regimens for complete clearance of microfilariae from the skin as determined by skin snips at 3, 12, and 18 months after treatment with IDA will be compared by treatment arm. (NCT04188301)
Timeframe: Baseline, 3 months, 12 months, & 18 months following treatment.

,,
InterventionCount of Skin Microfilaria (Geometric Mean)
BaselineMonth 3Month 12Month 18
IDA x 1 Dose1.732.59.0
IDA x 3 DosesNA2.14.78.6
IVM + ALB3.11.94.97.0

Adult Worm Burdens at 2 Years

Doppler detected worm nests at 2 years (NCT00511004)
Timeframe: 2 years from the time enrolled.

InterventionNumber of nests (Median)
Standard Therapy Annual DEC/ALB0
High Dose Annual DEC/ALB0
High Dose Semiannual DEC/ALB0

Brugia Specific Immunoglobulin G4 (IgG4) Antibodies

IgG4 antibodies directed against Brugia malayi antigen (NCT00511004)
Timeframe: 2 years

Interventionng/ml (Median)
Standard Therapy Annual DEC/ALB150
High Dose Annual DEC/ALB224
High Dose Semiannual DEC/ALB128

Microfilarial Counts at 1 Year

Night time microfilarial counts at 1 year (NCT00511004)
Timeframe: 1 year from time enrolled

InterventionMF/ML (Median)
Standard Therapy Annual DEC/ALB0
High Dose Annual DEC/ALB0
High Dose Semiannual DEC/ALB0

Microfilarial Levels at 2 Years

Night time microfilarial levels at 2 years (NCT00511004)
Timeframe: 2 years from time enrolled

InterventionMF/ML (Median)
Diethylcarbamazine/Albendazole -STD0
Diethylcarbamazine/Albendazole- HD10
Diethylcarbamazine/Albendazole-HD20

Reviews

2 reviews available for diethylcarbamazine and Eye Disorders

ArticleYear
Ocular onchocerciasis.
    Tropical diseases bulletin, 1977, Volume: 74, Issue:4

    Topics: Diethylcarbamazine; Eye; Eye Diseases; Female; Glaucoma; Humans; Iritis; Keratitis; Male; Onchocerci

1977
Ocular onchocerciasis in the horse.
    Equine veterinary journal, 1971, Volume: 3, Issue:4

    Topics: Animals; Anterior Chamber; Austria; California; Cataract; Ciliary Body; Conjunctivitis; Diethylcarba

1971

Trials

9 trials available for diethylcarbamazine and Eye Disorders

ArticleYear
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:5

    Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu

1983
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:5

    Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu

1983
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:5

    Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu

1983
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:5

    Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu

1983
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:5

    Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu

1983
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:5

    Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu

1983
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:5

    Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu

1983
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:5

    Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu

1983
Ocular and systemic complications of diethylcarbamazine therapy for onchocerciasis: association with circulating immune complexes.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:5

    Topics: Antigen-Antibody Complex; Complement System Proteins; Diethylcarbamazine; Eye Diseases; Humans; Immu

1983
Ocular changes with oral and transepidermal diethylcarbamazine therapy of onchocerciasis.
    The British journal of ophthalmology, 1981, Volume: 65, Issue:7

    Topics: Administration, Oral; Administration, Topical; Adult; Clinical Trials as Topic; Diethylcarbamazine;

1981
Double-blind study of ivermectin and diethylcarbamazine in African onchocerciasis patients with ocular involvement.
    Lancet (London, England), 1985, Jul-27, Volume: 2, Issue:8448

    Topics: Adolescent; Adult; Aged; Anthelmintics; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind M

1985
Chemotherapy of onchocerciasis with high doses of diethylcarbamazine or a single dose of ivermectin: microfilaria levels and side effects.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1988, Volume: 39, Issue:1

    Topics: Adult; Animals; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-B

1988
A double-blind comparison of the efficacy and safety of ivermectin and diethylcarbamazine in a placebo controlled study of Senegalese patients with onchocerciasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1986, Volume: 80, Issue:6

    Topics: Adolescent; Adult; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Method; Eye Diseases;

1986
Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1986, Volume: 104, Issue:6

    Topics: Adult; Anthelmintics; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Method; Eye; Eye Di

1986
Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1986, Volume: 104, Issue:6

    Topics: Adult; Anthelmintics; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Method; Eye; Eye Di

1986
Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1986, Volume: 104, Issue:6

    Topics: Adult; Anthelmintics; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Method; Eye; Eye Di

1986
Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1986, Volume: 104, Issue:6

    Topics: Adult; Anthelmintics; Clinical Trials as Topic; Diethylcarbamazine; Double-Blind Method; Eye; Eye Di

1986
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
    The British journal of ophthalmology, 1987, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl

1987
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
    The British journal of ophthalmology, 1987, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl

1987
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
    The British journal of ophthalmology, 1987, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl

1987
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
    The British journal of ophthalmology, 1987, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl

1987
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
    The British journal of ophthalmology, 1987, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl

1987
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
    The British journal of ophthalmology, 1987, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl

1987
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
    The British journal of ophthalmology, 1987, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl

1987
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
    The British journal of ophthalmology, 1987, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl

1987
Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
    The British journal of ophthalmology, 1987, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Anterior Chamber; Clinical Trials as Topic; Cornea; Diethylcarbamazine; Double-Bl

1987
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
    The New England journal of medicine, 1985, Jul-18, Volume: 313, Issue:3

    Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth

1985
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
    The New England journal of medicine, 1985, Jul-18, Volume: 313, Issue:3

    Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth

1985
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
    The New England journal of medicine, 1985, Jul-18, Volume: 313, Issue:3

    Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth

1985
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
    The New England journal of medicine, 1985, Jul-18, Volume: 313, Issue:3

    Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth

1985
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
    The New England journal of medicine, 1985, Jul-18, Volume: 313, Issue:3

    Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth

1985
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
    The New England journal of medicine, 1985, Jul-18, Volume: 313, Issue:3

    Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth

1985
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
    The New England journal of medicine, 1985, Jul-18, Volume: 313, Issue:3

    Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth

1985
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
    The New England journal of medicine, 1985, Jul-18, Volume: 313, Issue:3

    Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth

1985
Comparison of ivermectin and diethylcarbamazine in the treatment of onchocerciasis.
    The New England journal of medicine, 1985, Jul-18, Volume: 313, Issue:3

    Topics: Adult; Anthelmintics; Antiparasitic Agents; Clinical Trials as Topic; Cornea; Corneal Opacity; Dieth

1985
Topical diethylcarbamazine in ocular onchocerciasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1973, Volume: 67, Issue:5

    Topics: Administration, Topical; Adult; Anterior Chamber; Cameroon; Cornea; Diethylcarbamazine; Edema; Eye D

1973

Other Studies

42 other studies available for diethylcarbamazine and Eye Disorders

ArticleYear
Ocular and subcutaneous dirofilariasis in a Sri Lankan infant: an environmental hazard caused by dogs and mosquitoes.
    Paediatrics and international child health, 2013, Volume: 33, Issue:2

    Topics: Animals; Diethylcarbamazine; Dirofilaria repens; Dirofilariasis; Eye Diseases; Filaricides; Humans;

2013
[Asthenoscopic problems with a subconjunctival worm].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2002, Volume: 99, Issue:11

    Topics: Adult; Asthenopia; Diethylcarbamazine; Emergencies; Eye Diseases; Filaricides; Humans; Loiasis; Male

2002
[Hetrazan negative results in two human cases of ocular cysticercosis].
    Revista del Instituto de Salubridad y Enfermedades Tropicales, 1955, Volume: 15, Issue:4

    Topics: Cysticercosis; Diethylcarbamazine; Eye; Eye Diseases; Head; Humans

1955
Onchocerciasis in Tigray.
    International journal of dermatology, 2007, Volume: 46 Suppl 2

    Topics: Adult; Aged; Animals; Child; Diethylcarbamazine; Doxycycline; Eosinophilia; Ethiopia; Eye Diseases;

2007
Aqueous humor and serum IgE antibody in experimental ocular Onchocerca infection of guinea pigs.
    Ophthalmic research, 1983, Volume: 15, Issue:2

    Topics: Animals; Aqueous Humor; Diethylcarbamazine; Disease Models, Animal; Eye Diseases; Guinea Pigs; Immun

1983
[Treatment of filariases in a hospital setting. Complications - results].
    Annales de la Societe belge de medecine tropicale, 1981, Volume: 61, Issue:2

    Topics: Diethylcarbamazine; Dracunculiasis; Eye Diseases; Filariasis; Humans; Loiasis; Lymphatic Diseases

1981
[A clinical case of ocular onchocerciasis: clinical, angiofluorographic and developmental aspects].
    Journal francais d'ophtalmologie, 1984, Volume: 7, Issue:4

    Topics: Adult; Chorioretinitis; Choroid; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans;

1984
Loa loa: ocular filariasis in an African student in Missouri.
    Annals of ophthalmology, 1984, Volume: 16, Issue:5

    Topics: Adult; Cameroon; Diethylcarbamazine; Eye Diseases; Filariasis; Humans; Loiasis; Male; Missouri

1984
Eye screening in 2234 Sierra Leonean school students and detection of onchocerciasis.
    Documenta ophthalmologica. Advances in ophthalmology, 1983, Dec-15, Volume: 56, Issue:1-2

    Topics: Adolescent; Child; Diethylcarbamazine; Eye Diseases; Female; Humans; Male; Mass Screening; Onchocerc

1983
Ocular onchocerciasis with living microfilariae in the anterior chamber in two Dutch boys.
    Documenta ophthalmologica. Advances in ophthalmology, 1983, Dec-15, Volume: 56, Issue:1-2

    Topics: Adolescent; Anterior Chamber; Cameroon; Child; Child, Preschool; Diethylcarbamazine; Eye Diseases; H

1983
Onchocerciasis in Israel.
    Archives of dermatology, 1984, Volume: 120, Issue:4

    Topics: Adolescent; Diagnosis, Differential; Diethylcarbamazine; Ethiopia; Eye Diseases; Humans; Israel; Mal

1984
[Ocular oncocerciasis and its treatment].
    Therapeutische Umschau. Revue therapeutique, 1984, Volume: 41, Issue:4

    Topics: Adolescent; Adult; Child; Child, Preschool; Diethylcarbamazine; Eye Diseases; Female; Humans; Male;

1984
Equine ocular onchocerciasis: histopathologic study.
    American journal of veterinary research, 1982, Volume: 43, Issue:8

    Topics: Age Factors; Animals; Diethylcarbamazine; Disease Models, Animal; Eye Diseases; Horse Diseases; Hors

1982
Basis for treatment and prevention of ocular onchocerciasis.
    Revue internationale du trachome et de pathologie oculaire tropicale et subtropicale et de sante publique : organe de la Ligue contre le trachome avec la collaboration de l'International Organization against Trachoma et des organisation..., 1982, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Child, Preschool; Diethylcarbamazine; Drug Therap

1982
[Basis of the treatment and prevention of ocular onchocerciasis].
    Revue internationale du trachome et de pathologie oculaire tropicale et subtropicale et de sante publique : organe de la Ligue contre le trachome avec la collaboration de l'International Organization against Trachoma et des organisation..., 1982, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Africa; Antinematodal Agents; Diethylcarbamazine; Drug T

1982
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
    The British journal of ophthalmology, 1980, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M

1980
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
    The British journal of ophthalmology, 1980, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M

1980
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
    The British journal of ophthalmology, 1980, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M

1980
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
    The British journal of ophthalmology, 1980, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M

1980
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
    The British journal of ophthalmology, 1980, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M

1980
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
    The British journal of ophthalmology, 1980, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M

1980
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
    The British journal of ophthalmology, 1980, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M

1980
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
    The British journal of ophthalmology, 1980, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M

1980
Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
    The British journal of ophthalmology, 1980, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Child; Diethylcarbamazine; Eye Diseases; Fluorescein Angiography; Humans; Male; M

1980
[River blindness, infection by the filaria Onchocerca volvulus].
    Fortschritte der Medizin, 1980, Jun-12, Volume: 98, Issue:22

    Topics: Africa; Bone Diseases; Central America; Dermatitis; Diethylcarbamazine; Disease Outbreaks; Eye Disea

1980
[Onchocercosis: A disease full of puzzles (author's transl)].
    Klinika oczna, 1980, Volume: 82, Issue:4

    Topics: Diethylcarbamazine; Eye Diseases; Humans; Onchocerca; Onchocerciasis

1980
[Ocular manifestations of loaiasis].
    Journal francais d'ophtalmologie, 1978, Volume: 1, Issue:1

    Topics: Diethylcarbamazine; Eye Diseases; Eye Manifestations; Filariasis; Humans; Loiasis; Retinal Diseases;

1978
[Cameroon swelling; infection by the filaria Loa loa].
    Fortschritte der Medizin, 1979, Nov-08, Volume: 97, Issue:42

    Topics: Cameroon; Diethylcarbamazine; Edema; Eosinophilia; Eye Diseases; Filariasis; Humans; Insect Vectors;

1979
Ocular onchocerciasis.
    Bulletin of the World Health Organization, 1978, Volume: 56, Issue:1

    Topics: Diethylcarbamazine; Drug Therapy, Combination; Eye Diseases; Humans; Insect Control; Onchocerciasis;

1978
[Therapy of ocular onchocerciasis].
    Revue internationale du trachome et de pathologie oculaire tropicale et subtropicale : organe de la Ligue contre le trachome avec la collaboration de l'International Organization against Trachoma et des organisations nationales et inter..., 1979, Volume: 56, Issue:3-4

    Topics: Anthelmintics; Diethylcarbamazine; Eye Diseases; Filaricides; Humans; Keratitis; Onchocerciasis; Sur

1979
Filaria in the vitreous of the eye of man in peninsular Malaysia.
    The American journal of tropical medicine and hygiene, 1977, Volume: 26, Issue:6 Pt 1

    Topics: Diethylcarbamazine; Dirofilaria immitis; Dirofilariasis; Eye Diseases; Female; Humans; Malaysia; Mid

1977
Toxocariasis.
    Australian family physician, 1977, Volume: 6, Issue:12

    Topics: Animals; Ascariasis; Cats; Child; Diethylcarbamazine; Dogs; Eye Diseases; Humans; Infant; Larva Migr

1977
Effects of various concentrations of diethylcarbamazine citrate applied as eye drops in ocular onchocerciasis, and the possibilities of improved therapy from continuous non-pulsed delivery.
    The British journal of ophthalmology, 1978, Volume: 62, Issue:7

    Topics: Adult; Child; Cornea; Diethylcarbamazine; Dose-Response Relationship, Drug; Drug Administration Sche

1978
Further observations on the relationship between ocular onchocerciasis and the head nodule, and on the possible benefit of nodulectomy.
    The British journal of ophthalmology, 1978, Volume: 62, Issue:7

    Topics: Cameroon; Dermatologic Surgical Procedures; Diethylcarbamazine; Eye; Eye Diseases; Female; Head; Hum

1978
Further observations on the relationship between ocular onchocerciasis and the head nodule, and on the possible benefit of nodulectomy.
    The British journal of ophthalmology, 1978, Volume: 62, Issue:7

    Topics: Cameroon; Dermatologic Surgical Procedures; Diethylcarbamazine; Eye; Eye Diseases; Female; Head; Hum

1978
Further observations on the relationship between ocular onchocerciasis and the head nodule, and on the possible benefit of nodulectomy.
    The British journal of ophthalmology, 1978, Volume: 62, Issue:7

    Topics: Cameroon; Dermatologic Surgical Procedures; Diethylcarbamazine; Eye; Eye Diseases; Female; Head; Hum

1978
Further observations on the relationship between ocular onchocerciasis and the head nodule, and on the possible benefit of nodulectomy.
    The British journal of ophthalmology, 1978, Volume: 62, Issue:7

    Topics: Cameroon; Dermatologic Surgical Procedures; Diethylcarbamazine; Eye; Eye Diseases; Female; Head; Hum

1978
Further studies on the treatment of ocular onchocerciasis with diethylcarbamazine and suramin.
    The British journal of ophthalmology, 1978, Volume: 62, Issue:7

    Topics: Adolescent; Adult; Betamethasone; Child; Diethylcarbamazine; Drug Therapy, Combination; Eye Diseases

1978
Effects of diethylcarbamazine on ocular onchocerciasis.
    Tropenmedizin und Parasitologie, 1976, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Anterior Chamber; Child; Cornea; Diethylcarbamazine; Eye Diseases; Female; Fundus

1976
[Loaiasis and its therapeutic difficulties].
    Revue internationale du trachome et de pathologie oculaire tropicale et subtropicale et de sante publique : organe de la Ligue contre le trachome avec la collaboration de l'International Organization against Trachoma et des organisation..., 1986, Volume: 63, Issue:1-2

    Topics: Diethylcarbamazine; Eye Diseases; Filariasis; Humans; Ivermectin; Loiasis

1986
Need for caution in use of DEC for treatment of onchocerciasis.
    Tropical doctor, 1986, Volume: 16, Issue:2

    Topics: Diethylcarbamazine; Eye Diseases; Humans; Onchocerciasis

1986
Experimental ocular onchocerciasis in cynomolgus monkeys.
    Investigative ophthalmology & visual science, 1986, Volume: 27, Issue:4

    Topics: Animals; Anterior Chamber; Diethylcarbamazine; Disease Models, Animal; Eye; Eye Diseases; Macaca fas

1986
The Onchocerca volvulus micro- and macrofilarial responses in onchocerciasis patients to increased dosage of diethylcarbamazine.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1985, Volume: 36, Issue:3

    Topics: Administration, Oral; Administration, Topical; Adult; Animals; Anterior Chamber; Cornea; Diethylcarb

1985
Toxocara.
    Lancet (London, England), 1972, Apr-01, Volume: 1, Issue:7753

    Topics: Animals; Cats; Diethylcarbamazine; Dog Diseases; Dogs; Eye Diseases; Humans; Nematode Infections; Pa

1972
[The therapeutic difficulties of ocular onchocerciasis].
    Archives d'ophtalmologie et revue generale d'ophtalmologie, 1969, Volume: 29, Issue:11

    Topics: Arsenicals; Diethylcarbamazine; Eye Diseases; Humans; Onchocerciasis; Optic Nerve; Suramin; Thiabend

1969
Inflammatory pseudotumours of the orbit: a probable case of microfilarial granuloma of the orbit.
    Transactions of the ophthalmological societies of the United Kingdom, 1970, Volume: 90

    Topics: Adult; Dermoid Cyst; Diagnosis, Differential; Diethylcarbamazine; Exophthalmos; Eye Diseases; Filari

1970
The elusive Loa loa. A case report of ocular filariasis in Canada.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1973, Volume: 8, Issue:3

    Topics: Adult; Canada; Diethylcarbamazine; Eye Diseases; Female; Filariasis; Humans; Liberia; Loa

1973
Onchocerciasis (ocular).
    Annals of ophthalmology, 1971, Volume: 3, Issue:7

    Topics: Biopsy; Child; Diagnosis, Differential; Diethylcarbamazine; Diphenhydramine; Eye Diseases; Female; H

1971
Topical diethylcarbamazine in the treatment of ocular onchocerciasis.
    The American journal of tropical medicine and hygiene, 1970, Volume: 19, Issue:2

    Topics: Absorption; Animals; Diethylcarbamazine; Eye Diseases; Onchocerciasis; Ophthalmic Solutions; Rabbits

1970
Topical hetrazan in the treatment of ocular onchocerciasis.
    American journal of ophthalmology, 1970, Volume: 70, Issue:5

    Topics: Adult; Blindness; Conjunctiva; Diethylcarbamazine; Eye Diseases; Humans; Onchocerca; Onchocerciasis

1970
Impacted microfilaria in the lens capsule.
    The British journal of ophthalmology, 1971, Volume: 55, Issue:7

    Topics: Adult; Atropine; Diethylcarbamazine; Eye Diseases; Filariasis; Humans; Lens, Crystalline; Male

1971
[Eye involvement in onchocerciasis].
    Klinische Monatsblatter fur Augenheilkunde, 1967, Volume: 151, Issue:1

    Topics: Adult; Biopsy; Complement Fixation Tests; Cornea; Diagnosis, Differential; Diethylcarbamazine; Eye D

1967
[Ocular filariasis caused by Loa-loa: new clinico-therapeutic acquistitions].
    Annali di ottalmologia e clinica oculistica, 1968, Volume: 94, Issue:11

    Topics: Adult; Arsenicals; Diethylcarbamazine; Eye Diseases; Female; Filariasis; Humans; Loa

1968