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diethylcarbamazine and Collagen Diseases

diethylcarbamazine has been researched along with Collagen Diseases in 1 studies

Diethylcarbamazine: An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.

Collagen Diseases: Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that collagen was equivalent to connective tissue, but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term collagen diseases now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)

Research Excerpts

ExcerptRelevanceReference
"Pretreatment of cultured chondrosarcoma chondrocytes at 37 degrees C for 15 min with 15 mM diethylcarbamazine (DEC) followed by a 60-min pulse with [35S] sulfate in the presence of DEC resulted in an approximate 40% inhibition of synthesis and a 75% inhibition of secretion of 35S-proteoglycan."3.67Novel inhibition of proteoglycan synthesis and exocytosis by diethylcarbamazine in the Swarm rat chondrocyte. ( Austen, KF; Caulfield, JP; Hein, A; Parsons, WG; Stevens, RL, 1985)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stevens, RL1
Parsons, WG1
Austen, KF1
Hein, A1
Caulfield, JP1

Other Studies

1 other study available for diethylcarbamazine and Collagen Diseases

ArticleYear
Novel inhibition of proteoglycan synthesis and exocytosis by diethylcarbamazine in the Swarm rat chondrocyte.
    The Journal of biological chemistry, 1985, May-10, Volume: 260, Issue:9

    Topics: Animals; Cartilage; Chondrosarcoma; Colchicine; Collagen Diseases; Cytochalasin B; Diethylcarbamazin

1985