Page last updated: 2024-10-26

diethylcarbamazine and Bigfoot Disease

diethylcarbamazine has been researched along with Bigfoot Disease in 10 studies

Diethylcarbamazine: An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.

Research Excerpts

ExcerptRelevanceReference
"The results of mass treatment using low dosage diethylcarbamazine (DEC) in three small villages in West Flores, Indonesia, endemic for Brugia timori are described."5.27Low dosage diethylcarbamazine administered by villagers for the control of timorian filariasis. ( Oemijati, S; Partono, F; Soewarta, A, 1984)
"Because lymphatic filariasis (LF) elimination efforts are hampered by a dearth of economic information about the cost of mass drug administration (MDA) programs (using either albendazole with diethylcarbamazine [DEC] or albendazole with ivermectin), a multicenter study was undertaken to determine the costs of MDA programs to interrupt transmission of infection with LF."1.34National mass drug administration costs for lymphatic filariasis elimination. ( Aikins, M; Amarillo, ML; Belizario, VY; Brady, MA; Garshong, B; Goldman, AS; Guisinger, VH; Gyapong, J; Haddix, AC; Kabali, C; Kamal, HA; Kanjilal, S; Kyelem, D; Lizardo, J; Malecela, M; Mubyazi, G; Nitièma, PA; Ottesen, EA; Ramzy, RM; Rheingans, R; Streit, TG; Wallace, A, 2007)
"The results of mass treatment using low dosage diethylcarbamazine (DEC) in three small villages in West Flores, Indonesia, endemic for Brugia timori are described."1.27Low dosage diethylcarbamazine administered by villagers for the control of timorian filariasis. ( Oemijati, S; Partono, F; Soewarta, A, 1984)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's2 (20.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goldman, AS1
Guisinger, VH1
Aikins, M1
Amarillo, ML1
Belizario, VY1
Garshong, B1
Gyapong, J1
Kabali, C1
Kamal, HA1
Kanjilal, S1
Kyelem, D1
Lizardo, J1
Malecela, M1
Mubyazi, G1
Nitièma, PA1
Ramzy, RM1
Streit, TG1
Wallace, A1
Brady, MA1
Rheingans, R1
Ottesen, EA1
Haddix, AC1
Partono, F3
Oemijati, S2
Soewarta, A2
Ge, ZH1
Liu, WX1
Atta, NA1
Gawish, NA1
Fattah, IA1
Denham, DA1
Mergerian, H1
Bommer, W1
Dhanda, V1
Panicker, KN1
Stingl, P1
Cartel, JL1
Spiegel, A1
Nguyen, L1
Moulia-Pelat, JP1
Martin, PM1
Roux, JF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Albendazole Dose and Interval on Brugia Malayi Microfilarial Clearance in India: A Randomized, Open Label Study[NCT00511004]Phase 240 participants (Actual)Interventional2007-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Adult Worm Burdens at 2 Years

Doppler detected worm nests at 2 years (NCT00511004)
Timeframe: 2 years from the time enrolled.

InterventionNumber of nests (Median)
Standard Therapy Annual DEC/ALB0
High Dose Annual DEC/ALB0
High Dose Semiannual DEC/ALB0

Brugia Specific Immunoglobulin G4 (IgG4) Antibodies

IgG4 antibodies directed against Brugia malayi antigen (NCT00511004)
Timeframe: 2 years

Interventionng/ml (Median)
Standard Therapy Annual DEC/ALB150
High Dose Annual DEC/ALB224
High Dose Semiannual DEC/ALB128

Microfilarial Counts at 1 Year

Night time microfilarial counts at 1 year (NCT00511004)
Timeframe: 1 year from time enrolled

InterventionMF/ML (Median)
Standard Therapy Annual DEC/ALB0
High Dose Annual DEC/ALB0
High Dose Semiannual DEC/ALB0

Microfilarial Levels at 2 Years

Night time microfilarial levels at 2 years (NCT00511004)
Timeframe: 2 years from time enrolled

InterventionMF/ML (Median)
Diethylcarbamazine/Albendazole -STD0
Diethylcarbamazine/Albendazole- HD10
Diethylcarbamazine/Albendazole-HD20

Trials

1 trial available for diethylcarbamazine and Bigfoot Disease

ArticleYear
[Comparative efficacy of annual and semi-annual doses of ivermectin or diethylcarbamazine for the prevention of lymphatic filariasis].
    Revue d'epidemiologie et de sante publique, 1992, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Animals; Diethylcarbamazine; Dose-Response Relationship, Drug; Double-Blind Metho

1992

Other Studies

9 other studies available for diethylcarbamazine and Bigfoot Disease

ArticleYear
National mass drug administration costs for lymphatic filariasis elimination.
    PLoS neglected tropical diseases, 2007, Oct-31, Volume: 1, Issue:1

    Topics: Albendazole; Anthelmintics; Burkina Faso; Costs and Cost Analysis; Diethylcarbamazine; Dominican Rep

2007
The long term effects of repeated diethylcarbamazine administration with special reference to microfilaraemia and elephantiasis.
    Acta tropica, 1981, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Aged; Animals; Blood; Brugia; Child; Child, Preschool; Diethylcarbamazine; Elepha

1981
[A preliminary study on the changes in pathology and histochemistry of affected limbs in filarial elephantiasis after the treatment with the baking-bandage method and hetrazan].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1982, Volume: 2, Issue:2

    Topics: Adult; Bandages; Diethylcarbamazine; Elephantiasis; Female; Filariasis; Hot Temperature; Humans; Lym

1982
Filariasis in Indonesia: clinical manifestations and basic concepts of treatment and control.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984, Volume: 78, Issue:1

    Topics: Adult; Brugia; Child; Child, Preschool; Chronic Disease; Diethylcarbamazine; Elephantiasis; Female;

1984
Low dosage diethylcarbamazine administered by villagers for the control of timorian filariasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984, Volume: 78, Issue:3

    Topics: Brugia; Child; Community Health Workers; Diethylcarbamazine; Elephantiasis; Filariasis; Humans; Lymp

1984
Wuchereria bancrofti infections in Egypt and their treatment with diethylcarbamazine.
    Journal of the Egyptian Society of Parasitology, 1982, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Age Factors; Animals; Child; Child, Preschool; Diethylcarbamazine; Egypt; Elephan

1982
[Elephantiasis - a tropical nematode infection].
    Zeitschrift fur Lymphologie. Journal of lymphology, 1982, Volume: 6, Issue:1

    Topics: Adult; Diagnosis, Differential; Diethylcarbamazine; Elephantiasis; Female; Humans; Lymphedema; Male

1982
Self-help in Kerala.
    Nature, 1994, Sep-22, Volume: 371, Issue:6495

    Topics: Community Medicine; Diethylcarbamazine; Elephantiasis; Humans; India; Mosquito Control

1994
[Elephantiasis soon eliminated? New therapeutic concepts make mass treatment possible].
    MMW Fortschritte der Medizin, 2000, Aug-10, Volume: 142, Issue:31-32

    Topics: Albendazole; Diethylcarbamazine; Drug Administration Schedule; Elephantiasis; Filaricides; Humans; I

2000