diethylcarbamazine and Ascariasis studies

Diethylcarbamazine: An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.

Ascariasis: Infection by nematodes of the genus ASCARIS. Ingestion of infective eggs causes diarrhea and pneumonitis. Its distribution is more prevalent in areas of poor sanitation and where human feces are used for fertilizer.

Research Excerpts

Excerpt	Relevance	Reference
"Albendazole, ivermectin and the drug combinations gave significantly higher cure and egg reduction rates for ascariasis than diethylcarbamazine."	5.10	A comparison of the efficacy of single doses of albendazole, ivermectin, and diethylcarbamazine alone or in combinations against Ascaris and Trichuris spp. ( Amarillo, ME; Belizario, VY; Bugayong, MG; de Leon, WU; de los Reyes, AE; Macatangay, BJ, 2003)
"Diethylcarbamazine (DEC) is an important drug for treatment and control of lymphatic filariasis."	2.70	Efficacy of DEC against Ascaris and hookworm infections in schoolchildren. ( Meyrowitsch, DW; Simonsen, PE, 2001)
"However, studies of ascariasis in pigs have shown that the prevalence and the number of eggs detected in the stool do not correlate well with exposure of the herd to the parasite."	1.43	Community Rates of IgG4 Antibodies to Ascaris Haemoglobin Reflect Changes in Community Egg Loads Following Mass Drug Administration. ( Fischer, PU; Geldhof, P; Hokke, CH; Supali, T; Vlaminck, J; Weil, GJ, 2016)

Timeframe	Studies, this research(%)	All Research%
pre-1990	33 (84.62)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (12.82)	29.6817
2010's	1 (2.56)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Vlaminck, J	1
Supali, T	1
Geldhof, P	1
Hokke, CH	1
Fischer, PU	1
Weil, GJ	1
Belizario, VY	1
Amarillo, ME	1
de Leon, WU	1
de los Reyes, AE	1
Bugayong, MG	1
Macatangay, BJ	1
De Silva, NR	1
Pathmeswaran, A	1
Fernando, SD	1
Weerasinghe, CR	1
Selvaratnam, RR	1
Padmasiri, EA	1
Montresor, A	1
COLBOURNE, MJ	2
SINGH, J	1
RAGHAVAN, NG	1
MISRA, BG	1
KRISHNASWAMY, AK	1
ROY, R	1
MOJUMDAR, NG	1
KURIAN, PV	1
FANTA NUNEZ, E	1
GHANEM, MH	1
VAN DIJK, IJ	1
LOUGHLIN, EH	2
MULLIN, WG	2
ERHARDT, A	1
HUGON, J	1
GRIESEMER, RA	1
GIBSON, JP	1
CHARI, MV	1
HIREMATH, RS	1
SMIT, AM	1
SANDOSHAM, AA	1
SHRAND, H	1
CORCOS, A	1
DUPOUX, R	1
ABITBOL, S	1
RAPPAPORT, I	1
JOSEPH, AA	1
HOEKENGA, MT	2
ETTELDORF, JN	1
CRAWFORD, LV	2
Aggarwal, B	1
Sharma, M	1
Singh, T	1
Sanguigni, S	1
Sebastiani, A	1
Marangi, M	1
Bianchini, C	1
Aceti, A	1
Goel, RG	1
Bhan, MK	1
Fazal, MI	1
Srivastava, RN	1
Meyrowitsch, DW	1
Simonsen, PE	1
Mani, TR	1
Rajendran, R	1
Munirathinam, A	1
Sunish, IP	1
Md Abdullah, S	1
Augustin, DJ	1
Satyanarayana, K	1
Chand, N	1
Eyre, P	1
Sprent, JF	1
Jones, HI	1
Wiseman, RA	1
Woodruff, AW	1
Pettitt, LE	1
Dafalla, AA	1
Wendler, H	1
Tumada, LR	1
Margono, SS	1
Saw, HS	1
Somasundaram, K	1
Kamath, R	1
Mallén, MS	1
Burren, CH	1

Article	Year
A comparison of the efficacy of single doses of albendazole, ivermectin, and diethylcarbamazine alone or in combinations against Ascaris and Trichuris spp. Bulletin of the World Health Organization, 2003, Volume: 81, Issue:1 Topics: Adolescent; Albendazole; Anthelmintics; Ascariasis; Child; Diethylcarbamazine; Drug Therapy, Combina	2003
Efficacy of DEC against Ascaris and hookworm infections in schoolchildren. Tropical medicine & international health : TM & IH, 2001, Volume: 6, Issue:9 Topics: Adolescent; Ascariasis; Child; Diethylcarbamazine; Double-Blind Method; Female; Filaricides; Hookwor	2001

Article	Year
Community Rates of IgG4 Antibodies to Ascaris Haemoglobin Reflect Changes in Community Egg Loads Following Mass Drug Administration. PLoS neglected tropical diseases, 2016, Volume: 10, Issue:3 Topics: Albendazole; Animals; Anthelmintics; Antibodies, Helminth; Ascariasis; Ascaris lumbricoides; Blottin	2016
Impact of mass chemotherapy for the control of filariasis on geohelminth infections in Sri Lanka. Annals of tropical medicine and parasitology, 2003, Volume: 97, Issue:4 Topics: Albendazole; Animals; Anthelmintics; Ascariasis; Ascaris lumbricoides; Child; Diethylcarbamazine; Dr	2003
Treatment of ascariasis with hetrazan in the Gold Coast. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1952, Volume: 46, Issue:6 Topics: Ascariasis; Diethylcarbamazine; Ghana	1952
A note on the ascaricidal value of hetrazan. The Indian medical gazette, 1952, Volume: 87, Issue:8 Topics: Ascariasis; Diethylcarbamazine; Filariasis	1952
Diethylcarbamazine in ascariasis, a preliminary report. Indian journal of pediatrics, 1953, Volume: 20, Issue:77 Topics: Ascariasis; Diethylcarbamazine	1953
Treatment of ascariasis in children with hetrazan. Journal of the Indian Medical Association, 1953, Volume: 22, Issue:12 Topics: Ascariasis; Diethylcarbamazine; Humans	1953
[Comparative study of the effectiveness of hetrazan, santonin and hexylresorcinol in the treatment of ascariasis in children]. Revista chilena de pediatria, 1953, Volume: 24, Issue:8 Topics: Anthelmintics; Ascariasis; Diethylcarbamazine; Hexylresorcinol; Santonin	1953
The treatment of ascariasis and ancylostomiasis with hetrazan (diethylcarbamazine). Transactions of the Royal Society of Tropical Medicine and Hygiene, 1954, Volume: 48, Issue:1 Topics: Ancylostomiasis; Ascariasis; Diethylcarbamazine; Hookworm Infections	1954
[Diethylcarbamazine, a new remedy for ascariasis]. Maandschrift voor kindergeneeskunde, 1954, Volume: 22, Issue:2 Topics: Ascariasis; Diethylcarbamazine	1954
Hetrazan in ascariasis. The Medical clinics of North America, 1954, Volume: 11 Topics: Ascariasis; Diethylcarbamazine; Humans	1954
[Chemotherapeutic studies on hetrazan]. Zeitschrift fur Tropenmedizin und Parasitologie, 1954, Volume: 5, Issue:3 Topics: Ancylostomiasis; Ascariasis; Diethylcarbamazine; Hookworm Infections; Oxyuriasis; Trichinellosis	1954
Experimentation of diethylcarbamazine citrate and paludrine in ascariasis. Annales de la Societe belge de medecine tropicale (1920), 1956, Apr-30, Volume: 36, Issue:2 Topics: Ascariasis; Diethylcarbamazine; Proguanil	1956
THE ESTABLISHMENT OF AN ASCARID-FREE BEAGLE DOG COLONY. Journal of the American Veterinary Medical Association, 1963, Nov-01, Volume: 143 Topics: Animals; Animals, Newborn; Ascariasis; Diethylcarbamazine; Dog Diseases; Dogs; Research; Veterinary	1963
A COMPARATIVE STUDY OF ORAL AND PARENTERAL DIETHYLCARBAMAZINE CITRATE IN THE TREATMENT OF ASCARIASIS. Journal of the Indian Medical Association, 1963, Nov-01, Volume: 41 Topics: Adolescent; Anemia; Ascariasis; Child; Diethylcarbamazine; Geriatrics; Heart Failure; Humans; Liver	1963
THE EOSINOPHILIC REACTION IN HELMINTHIC INFECTIONS. Annales de la Societe belge de medecine tropicale (1920), 1963, Aug-31, Volume: 43 Topics: Animals; Ascariasis; Diethylcarbamazine; Eosinophilia; Helminthiasis; Humans; Nematode Infections; O	1963
RESULTS OF FILARIASIS CONTROL PROGRAMME IN THE FEDERATION OF MALAYA. The Medical journal of Malaya, 1964, Volume: 18 Topics: Animals; Anopheles; Ascariasis; Communicable Disease Control; Diethylcarbamazine; Filariasis; Humans	1964
VISCERAL LARVA MIGRANS. TOXOCARA CANIS INFECTION. Lancet (London, England), 1964, Jun-20, Volume: 1, Issue:7347 Topics: Animals; Ascariasis; Diagnosis, Differential; Diethylcarbamazine; Dogs; Eosinophilia; Eye Manifestat	1964
[Treatment of intestinal parasitosis with roundworms by diethyl-carbamyl-4-methyl piperazine (notezine)]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1951, Volume: 44, Issue:3-4 Topics: Ancylostomiasis; Animals; Ascariasis; Diethylcarbamazine; Hookworm Infections; Humans; Intestinal Di	1951
Treatment of human ascariasis with hetrazan; the use of a syrup containing 1-diethylcarbamyl-4-methyl piperazine dihydrogen citrate (hetrazan). Lancet (London, England), 1951, Dec-29, Volume: 2, Issue:6696 Topics: Ascariasis; Citrates; Diethylcarbamazine; Food; Piperazines	1951
Treatment of ascariasis with 1-diethylcarbamyl-4-methylpiperazine hydrochloride. Southern medical journal, 1951, Volume: 44, Issue:12 Topics: Ascariasis; Diethylcarbamazine; Piperazines	1951
Treatment of ascariasis in children with hetrazan syrup. The American journal of tropical medicine and hygiene, 1952, Volume: 1, Issue:4 Topics: Ascariasis; Diethylcarbamazine; Food	1952
Unsuccessful treatment of ascariasis with hetrazan. Lancet (London, England), 1950, May-27, Volume: 1, Issue:6613 Topics: Ascariasis; Diethylcarbamazine	1950
Treatment of ascariasis in children; use of 1-diethylcarbamyl-4-methyl piperazine dihydrogen citrate (hetrazan). Journal of the American Medical Association, 1950, Jul-01, Volume: 143, Issue:9 Topics: Ascariasis; Citrates; Diethylcarbamazine; Piperazine; Piperazines	1950
Treatment of ascariasis in children; use of 1-diethylcarbamyl-4-methyl piperazine dihydrogen citrate (hetrazan). Journal of the American Medical Association, 1950, Jul-01, Volume: 143, Issue:9 Topics: Ascariasis; Citrates; Diethylcarbamazine; Piperazines	1950
Acute eosinophilic pneumonia due to round worm infestation. Indian journal of pediatrics, 2008, Volume: 75, Issue:3 Topics: Ascariasis; Diagnosis, Differential; Diethylcarbamazine; Filaricides; Humans; Infant; Male; Pulmonar	2008
[Filariasis: clinico-therapeutic considerations on 24 cases]. La Clinica terapeutica, 1984, Apr-15, Volume: 109, Issue:1 Topics: Ascariasis; Diethylcarbamazine; Filariasis; Humans; Levamisole; Loiasis; Mansonelliasis; Onchocercia	1984
Hypereosinophilia pulmonary symptoms and ascariasis. Indian pediatrics, 1982, Volume: 19, Issue:4 Topics: Adolescent; Adult; Ascariasis; Child; Child, Preschool; Diethylcarbamazine; Female; Humans; Male; Pu	1982
Efficacy of co-administration of albendazole and diethylcarbamazine against geohelminthiases: a study from South India. Tropical medicine & international health : TM & IH, 2002, Volume: 7, Issue:6 Topics: Adolescent; Albendazole; Anthelmintics; Ascariasis; Child; Child, Preschool; Cross-Sectional Studies	2002
Toxocariasis. Australian family physician, 1977, Volume: 6, Issue:12 Topics: Animals; Ascariasis; Cats; Child; Diethylcarbamazine; Dogs; Eye Diseases; Humans; Infant; Larva Migr	1977
The treatment of toxocaral infection: some experimental and clinical observations. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1971, Volume: 65, Issue:5 Topics: Animals; Antibodies; Ascariasis; Blood Proteins; Child, Preschool; Diethylcarbamazine; Fluorescent A	1971
A study of the effect of diethylcarbamazine and thiabendazole on experimental Toxocara canis infection in mice. The Journal of tropical medicine and hygiene, 1972, Volume: 75, Issue:8 Topics: Animals; Ascariasis; Diethylcarbamazine; Eosinophils; Injections, Intraperitoneal; Larva; Leukocyte	1972
[The visceral larva migrans syndrome due to Toxocara canis]. Munchener medizinische Wochenschrift (1950), 1972, Sep-29, Volume: 114, Issue:39 Topics: Animals; Ascariasis; Biopsy; Child, Preschool; Diethylcarbamazine; Dogs; Eosinophilia; Hepatomegaly;	1972
Cysticercosis in the area of the Wissel Lakes, West Irian. The Southeast Asian journal of tropical medicine and public health, 1973, Volume: 4, Issue:3 Topics: Adolescent; Adult; Ascariasis; Cysticercosis; Diethylcarbamazine; Female; Headache; Hookworm Infecti	1973
Hepatic ascariasis. A case report and review of the literature. Archives of surgery (Chicago, Ill. : 1960), 1974, Volume: 108, Issue:5 Topics: Ascariasis; Biopsy; Child, Preschool; Citrates; Diethylcarbamazine; Humans; Liver Diseases; Male; Me	1974
Diethylcarbamazine citrate. The Journal of allergy, 1971, Volume: 47, Issue:2 Topics: Ascariasis; Asthma; Citrates; Diethylcarbamazine; Humans	1971
Experimental toxocariasis. II. Toxocara canis in the mouse as a system for testing compounds of potential anthelmintic acitivity. Zeitschrift fur Parasitenkunde (Berlin, Germany), 1968, Volume: 30, Issue:2 Topics: Animals; Anthelmintics; Ascariasis; Brain; Diethylcarbamazine; Male; Mice; Thiabendazole; Toxocara	1968

diethylcarbamazine and Ascariasis

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