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diethylcarbamazine and Anoxemia

diethylcarbamazine has been researched along with Anoxemia in 15 studies

Diethylcarbamazine: An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.

Research Excerpts

ExcerptRelevanceReference
" Here we investigated whether a cyclooxygenase-2 (COX-2) inhibitor or diethylcarbamazine (DEC), that is known for its 5-lipoxygenase inhibiting and antioxidant actions, modify the development of PAH in the Sugen 5416/hypoxia (SuHx) rat model."3.81Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension. ( Abbate, A; Al-Husseini, A; Chalfant, CE; Drake, JI; Farkas, L; Kraskauskas, D; Van Tassel, B; Voelkel, NF; Wijesinghe, DS, 2015)
"We studied whether intravenously administered inhibitors of leukotriene synthesis (diethylcarbamazine, DEC) or end-organ effect (FPL-55712) would change the distribution of regional pulmonary blood flow (rPBF) caused by left lower lobe (LLL) alveolar hypoxia in dogs."3.67Leukotriene inhibitors do not block hypoxic pulmonary vasoconstriction in dogs. ( Dennis, DR; Schuster, DP, 1987)
" Diethylcarbamazine citrate (DEC), a lipoxygenase inhibitor, inhibited these effects of ethanol in a dosage of 200 mg/kg."1.28Effects of acute ingestion of ethanol on hemodynamics and hypoxic pulmonary vasoconstriction in dogs--role of leukotrienes. ( Lu, CY; Wang, DX; Yu, SB, 1992)
"Diethylcarbamazine (DEC) is an inhibitor of lipoxygenase, with protective effects in several experimental models of anaphylaxis and lung dysfunction."1.27Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep. ( Brigham, KL; Kobayashi, T; Newman, JH; Zadoff, AD, 1986)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's5 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al-Husseini, A1
Wijesinghe, DS1
Farkas, L1
Kraskauskas, D1
Drake, JI1
Van Tassel, B1
Abbate, A1
Chalfant, CE1
Voelkel, NF3
Leffler, CW1
Mitchell, JA1
Green, RS1
Schützer, KM1
Larsson, A1
Risberg, B1
Falk, A1
Light, RB1
Lu, CY1
Wang, DX4
Yu, SB2
Russell, PC1
Emery, CJ1
Nicholl, J1
Barer, GR1
Howard, P1
Yang, GT1
Zou, AP1
Cheng, G1
Pi, YQ1
Wang, WH1
Bonnet, P1
Argibay, JA1
Garnier, D1
Lonigro, AJ1
Sprague, RS1
Stephenson, AH1
Dahms, TE1
Schuster, DP1
Dennis, DR1
Burghuber, OC1
Morganroth, ML2
Stenmark, KR2
Morris, KG2
Reeves, JT2
Zadoff, AD1
Kobayashi, T1
Brigham, KL1
Newman, JH1
Li, SR1
Murphy, RC1
Mathias, M1

Other Studies

15 other studies available for diethylcarbamazine and Anoxemia

ArticleYear
Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arterioles; Cyclooxyg

2015
Cardiovascular effects of leukotrienes in neonatal piglets. Role in hypoxic pulmonary vasoconstriction?
    Circulation research, 1984, Volume: 55, Issue:6

    Topics: Animals; Animals, Newborn; Catechols; Chromones; Diethylcarbamazine; Hypoxia; Masoprocol; Pulmonary

1984
Leukotriene receptor antagonism prevents lung protein leakage and hypoxaemia in a septic cat model.
    The European respiratory journal, 1994, Volume: 7, Issue:6

    Topics: Analysis of Variance; Animals; Capillary Permeability; Cats; Diethylcarbamazine; Disease Models, Ani

1994
Effect of sodium nitroprusside and diethylcarbamazine on hypoxic pulmonary vasoconstriction and regional distribution of pulmonary blood flow in experimental pneumonia.
    American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cardiac Output; Diethylca

1996
Effects of acute ingestion of ethanol on hemodynamics and hypoxic pulmonary vasoconstriction in dogs--role of leukotrienes.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1992, Volume: 12, Issue:4

    Topics: Animals; Blood Pressure; Diethylcarbamazine; Dogs; Ethanol; Female; Hemodynamics; Hypoxia; Leukotrie

1992
Interactions between hypoxic and almitrine-induced vasoconstriction in the rat lung.
    Clinical science (London, England : 1979), 1992, Volume: 82, Issue:3

    Topics: Almitrine; Animals; Blood Pressure; Chlorpheniramine; Cold Temperature; Diethylcarbamazine; Dose-Res

1992
[Influence of cigarette smoking on the hypoxic pulmonary vasoconstriction in isolated rat lungs--the role of prostaglandins and leukotrienes].
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1992, Volume: 12, Issue:1

    Topics: Animals; Diethylcarbamazine; Hypoxia; In Vitro Techniques; Indomethacin; Leukotrienes; Lung; Nicotia

1992
[The role of lipoxygenase and cyclooxygenase metabolites in acute hypoxic pulmonary vasoconstriction in piglets].
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1989, Volume: 9, Issue:4

    Topics: Animals; Diethylcarbamazine; Hypoxia; Lipoxygenase; Male; Prostaglandin-Endoperoxide Synthases; Pulm

1989
Contractile responses to hypoxia of isolated rings from the left branch of rabbit pulmonary artery.
    Fundamental & clinical pharmacology, 1989, Volume: 3, Issue:2

    Topics: Acetylcholine; Animals; Arachidonic Acids; Diethylcarbamazine; Endothelium, Vascular; Hypoxia; In Vi

1989
Relationship of leukotriene C4 and D4 to hypoxic pulmonary vasoconstriction in dogs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:6

    Topics: Animals; Blood Pressure; Carbon Dioxide; Diethylcarbamazine; Dogs; Hypoxia; Lung; Male; Oxygen; Part

1988
Leukotriene inhibitors do not block hypoxic pulmonary vasoconstriction in dogs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 62, Issue:5

    Topics: Animals; Chromones; Diethylcarbamazine; Dogs; Hypoxia; Nitroprusside; Pulmonary Alveoli; Pulmonary C

1987
[Inhibition of hypoxic pulmonary vasoconstriction by leukotriene blockade].
    Wiener klinische Wochenschrift, 1986, Feb-21, Volume: 98, Issue:4

    Topics: Angiotensin II; Animals; Diethylcarbamazine; Dose-Response Relationship, Drug; Hypertension, Pulmona

1986
Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 60, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Diethylcarbamazine; Endotoxins; Hemodynamics; Hypertension, P

1986
The role of leukotrienes in acute hypoxic pulmonary vasoconstriction in rats.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1986, Volume: 6, Issue:4

    Topics: Animals; Chromones; Diethylcarbamazine; Female; Hemodynamics; Hypoxia; Lung; Male; Rats; Rats, Inbre

1986
Diethylcarbamazine inhibits acute and chronic hypoxic pulmonary hypertension in awake rats.
    The American review of respiratory disease, 1985, Volume: 131, Issue:4

    Topics: Acute Disease; Altitude; Animals; Blood Pressure; Body Weight; Chronic Disease; Diethylcarbamazine;

1985