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diethylcarbamazine and Acute Liver Injury, Drug-Induced

diethylcarbamazine has been researched along with Acute Liver Injury, Drug-Induced in 11 studies

Diethylcarbamazine: An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.

Research Excerpts

ExcerptRelevanceReference
"Chronic inflammation was induced by i."5.40Diethylcarbamazine reduces chronic inflammation and fibrosis in carbon tetrachloride- (CCl₄-) induced liver injury in mice. ( Barbosa, KP; de França, ME; Luna, RL; Nunes, AK; Oliveira, AG; Oliveira, WH; Pastor, AF; Peixoto, CA; Rocha, SW; Rodrigues, GB, 2014)
" It is feasible that both are due to the accumulation of toxic metabolite(s), and arene oxides may probably be considered as damaging derivatives of carbamazepine metabolism."2.41Carbamazepine-provoked hepatotoxicity and possible aetiopathological role of glutathione in the events. Retrospective review of old data and call for new investigation. ( Kalapos, MP, 2002)
"Chronic inflammation was induced by i."1.40Diethylcarbamazine reduces chronic inflammation and fibrosis in carbon tetrachloride- (CCl₄-) induced liver injury in mice. ( Barbosa, KP; de França, ME; Luna, RL; Nunes, AK; Oliveira, AG; Oliveira, WH; Pastor, AF; Peixoto, CA; Rocha, SW; Rodrigues, GB, 2014)
" An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems."1.36Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greene, N1
Fisk, L1
Naven, RT1
Note, RR1
Patel, ML1
Pelletier, DJ1
Ekins, S1
Williams, AJ1
Xu, JJ1
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W1
Rocha, SW1
de França, ME1
Rodrigues, GB1
Barbosa, KP1
Nunes, AK1
Pastor, AF1
Oliveira, AG1
Oliveira, WH1
Luna, RL1
Peixoto, CA1
Kalapos, MP1
Gonzàlez, R1
Ancheta, O1
Màrquez, M1
Rodriguez, S1
Bunch, SE2
Dickinson, EO1
Dodds, WJ1
Vaden, SL1
Duncan, DE1
Cullen, JM1
Wendel, A1
Tiegs, G1
Hardy, RM1
Polzen, DJ1
O'Brien, TD1

Reviews

2 reviews available for diethylcarbamazine and Acute Liver Injury, Drug-Induced

ArticleYear
Carbamazepine-provoked hepatotoxicity and possible aetiopathological role of glutathione in the events. Retrospective review of old data and call for new investigation.
    Adverse drug reactions and toxicological reviews, 2002, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Child; Di

2002
Hepatotoxicity associated with pharmacologic agents in dogs and cats.
    The Veterinary clinics of North America. Small animal practice, 1993, Volume: 23, Issue:3

    Topics: Animals; Anthelmintics; Benzimidazoles; Cat Diseases; Cats; Chemical and Drug Induced Liver Injury;

1993

Other Studies

9 other studies available for diethylcarbamazine and Acute Liver Injury, Drug-Induced

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship;

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Diethylcarbamazine reduces chronic inflammation and fibrosis in carbon tetrachloride- (CCl₄-) induced liver injury in mice.
    Mediators of inflammation, 2014, Volume: 2014

    Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Col

2014
Hepatoprotective effects of diethylcarbamazine in acute liver damage induced by carbon tetrachloride in rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:6

    Topics: Alanine Transaminase; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur

1994
Questions basis for conclusions in report on drug-induced hepatotoxicosis.
    Journal of the American Veterinary Medical Association, 1988, Sep-15, Volume: 193, Issue:6

    Topics: Animals; Benzimidazoles; Chemical and Drug Induced Liver Injury; Diethylcarbamazine; Dog Diseases; D

1988
Hepatotoxicosis associated with heartworm/hookworm preventive medication in a dog.
    Journal of the American Veterinary Medical Association, 1988, Mar-01, Volume: 192, Issue:5

    Topics: Animals; Antinematodal Agents; Benzimidazoles; Chemical and Drug Induced Liver Injury; Diethylcarbam

1988
A novel biologically active seleno-organic compound--VI. Protection by ebselen (PZ 51) against galactosamine/endotoxin-induced hepatitis in mice.
    Biochemical pharmacology, 1986, Jul-01, Volume: 35, Issue:13

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azoles; Chemical and Drug Induced Liver

1986
Report of drug-associated hepatitis in dogs.
    Journal of the American Veterinary Medical Association, 1986, Oct-15, Volume: 189, Issue:8

    Topics: Animals; Anthelmintics; Benzimidazoles; Chemical and Drug Induced Liver Injury; Diethylcarbamazine;

1986