diethyl-maleate and Paralysis

diethyl-maleate has been researched along with Paralysis* in 1 studies

Other Studies

1 other study(ies) available for diethyl-maleate and Paralysis

Article	Year
Effect of diethyl maleate on acrylamide induced neuropathy in rats. Toxicology letters, 1980, Volume: 6, Issue:6 Pre-administration of diethyl maleate (DEM) to rats resulted in an earlier onset and development of hind limb paralysis following acrylamide administration than in rats treated with acrylamide only. A marked depletion of brain biogenic amine content and of glutathione levels was also observed in the DEM pretreated groups. Depletion of cellular glutathione would appear to lead to an increased neurotoxicity of acrylamide. Topics: Acrylamides; Animals; Biotransformation; Brain Chemistry; Drug Synergism; Female; Glutathione; Glutathione Transferase; Maleates; Paralysis; Rats	1980

Article

Year

Effect of diethyl maleate on acrylamide induced neuropathy in rats.

Toxicology letters, 1980, Volume: 6, Issue:6

Pre-administration of diethyl maleate (DEM) to rats resulted in an earlier onset and development of hind limb paralysis following acrylamide administration than in rats treated with acrylamide only. A marked depletion of brain biogenic amine content and of glutathione levels was also observed in the DEM pretreated groups. Depletion of cellular glutathione would appear to lead to an increased neurotoxicity of acrylamide.

Topics: Acrylamides; Animals; Biotransformation; Brain Chemistry; Drug Synergism; Female; Glutathione; Glutathione Transferase; Maleates; Paralysis; Rats

1980