Compounds > diethanolamine
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diethanolamine and Choline Deficiency

diethanolamine has been researched along with Choline Deficiency in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lehman-McKeeman, LD1
Kamendulis, LM; Leung, HW; Stott, WT1
Bachman, AN; Goodman, JI; Kamendulis, LM1
Bartels, MJ; Brzak, KA; Mar, M; Markham, DA; Stott, WT; Thornton, CM; Zeisel, SH1
Gamsky, EA; Lehman-McKeeman, LD1
Newberne, PM1
Gamsky, EA; Hicks, SM; Lehman-McKeeman, LD; Mar, MH; Vassallo, JD; Zeisel, SH1

Reviews

2 review(s) available for diethanolamine and Choline Deficiency

ArticleYear
Review of the carcinogenic activity of diethanolamine and evidence of choline deficiency as a plausible mode of action.
    Regulatory toxicology and pharmacology : RTP, 2005, Volume: 43, Issue:3

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Choline; Choline Deficiency; Ethanolamines; Female; Humans; Male; Mice; Mutagenicity Tests; Neoplasms; Phospholipids; Rats; Rats, Inbred F344

2005
Choline deficiency associated with diethanolamine carcinogenicity.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 67, Issue:1

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Choline Deficiency; Ethanolamines; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred Strains

2002

Other Studies

5 other study(ies) available for diethanolamine and Choline Deficiency

ArticleYear
Incorporating mechanistic data into risk assessment.
    Toxicology, 2002, Dec-27, Volume: 181-182

    Topics: Animals; Carcinogenicity Tests; Carcinogens; CHO Cells; Choline Deficiency; Cricetinae; Ethanolamines; Humans; Mice; Rats; Risk Assessment; S-Adenosylmethionine

2002
Diethanolamine and phenobarbital produce an altered pattern of methylation in GC-rich regions of DNA in B6C3F1 mouse hepatocytes similar to that resulting from choline deficiency.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 90, Issue:2

    Topics: Animals; Cells, Cultured; Choline Deficiency; DNA; DNA Methylation; Ethanolamines; GC Rich Sequence; Hepatocytes; Male; Mice; Mice, Inbred Strains; Phenobarbital; Polymerase Chain Reaction

2006
Potential mechanisms of tumorigenic action of diethanolamine in mice.
    Toxicology letters, 2000, Apr-03, Volume: 114, Issue:1-3

    Topics: Administration, Cutaneous; Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carcinogens; Choline; Choline Deficiency; Diethylnitrosamine; Ethanolamines; Gastrointestinal Contents; Glycerylphosphorylcholine; Liver; Male; Mice; Phosphatidylcholines; Phosphatidylethanolamines; Phosphorylcholine; Sodium Nitrite; Sphingomyelins

2000
Choline supplementation inhibits diethanolamine-induced morphological transformation in syrian hamster embryo cells: evidence for a carcinogenic mechanism.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 55, Issue:2

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Choline; Choline Deficiency; Cricetinae; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethanolamines; Mesocricetus; Phosphatidylcholines; Phospholipids

2000
Diethanolamine induces hepatic choline deficiency in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 67, Issue:1

    Topics: Administration, Cutaneous; Animals; Betaine; Carcinogens; Choline Deficiency; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Ethanolamines; Glycerylphosphorylcholine; Liver; Male; Mice; Mice, Inbred C57BL; No-Observed-Adverse-Effect Level; Phosphatidylcholines; Phosphorylcholine; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity

2002