Compounds > didimethylsulfoxide-dichloroplatinum(ii)

didimethylsulfoxide-dichloroplatinum(ii) and Colorectal-Neoplasms

didimethylsulfoxide-dichloroplatinum(ii) has been researched along with Colorectal-Neoplasms* in 3 studies

Reviews

1 review(s) available for didimethylsulfoxide-dichloroplatinum(ii) and Colorectal-Neoplasms

Article	Year
Developments of the fluoropyrimidines as inhibitors of thymidylate synthetase: pharmacologic and clinical aspects. Journal of surgical oncology. Supplement, 1991, Volume: 2 Topics: Animals; Antineoplastic Agents; Colorectal Neoplasms; Drug Synergism; Floxuridine; Fluorouracil; Humans; Leucovorin; Organoplatinum Compounds; Prodrugs; Pyrimidines; Thymidylate Synthase	1991

Trials

1 trial(s) available for didimethylsulfoxide-dichloroplatinum(ii) and Colorectal-Neoplasms

Article	Year
Two consecutive clinical trials on cisplatin (CDDP), hepatic arterial infusion (HAI), and i.v. 5-fluorouracil (5-FU) chemotherapy for unresectable colorectal liver metastases: an alternative to FUdR-based regimens? Journal of surgical oncology. Supplement, 1991, Volume: 2 Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Evaluation; Floxuridine; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Middle Aged; Organoplatinum Compounds; Survival Rate	1991

Article

Year

Two consecutive clinical trials on cisplatin (CDDP), hepatic arterial infusion (HAI), and i.v. 5-fluorouracil (5-FU) chemotherapy for unresectable colorectal liver metastases: an alternative to FUdR-based regimens?

Journal of surgical oncology. Supplement, 1991, Volume: 2

Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Evaluation; Floxuridine; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Middle Aged; Organoplatinum Compounds; Survival Rate

1991

Other Studies

1 other study(ies) available for didimethylsulfoxide-dichloroplatinum(ii) and Colorectal-Neoplasms

Article	Year
Intraperitoneal hyperthermic treatment for peritoneal dissemination of colorectal cancers. Diseases of the colon and rectum, 1992, Volume: 35, Issue:10 Continuous hyperthermic peritoneal perfusion (CHPP) combined with administration of anticancer drugs was performed in eight colorectal cancer patients with peritoneal dissemination. An overall response rate of 50 percent was achieved in the eight patients. Two of three complete responders are long, recurrence-free survivors for 15 and 30 months. The two-year survival has been achieved in 18.8 percent of the patients receiving CHPP, and this rate is significantly higher than the rates in P2 and P3 patients who did not receive CHPP. The complications of CHPP with administration of anticancer drugs were mild bone marrow suppression in two (25 percent) of the eight patients and also a mild grade of renal dysfunction in one (12.5 percent), though not lethal. The results suggest that the combination of CHPP with the administration of anticancer drugs is a safe and effective therapy for peritoneal dissemination of colorectal cancers. Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Colorectal Neoplasms; Female; Humans; Hyperthermia, Induced; Male; Middle Aged; Mitomycin; Organoplatinum Compounds; Peritoneal Neoplasms; Survival Analysis	1992

Article

Year

Intraperitoneal hyperthermic treatment for peritoneal dissemination of colorectal cancers.

Diseases of the colon and rectum, 1992, Volume: 35, Issue:10

Continuous hyperthermic peritoneal perfusion (CHPP) combined with administration of anticancer drugs was performed in eight colorectal cancer patients with peritoneal dissemination. An overall response rate of 50 percent was achieved in the eight patients. Two of three complete responders are long, recurrence-free survivors for 15 and 30 months. The two-year survival has been achieved in 18.8 percent of the patients receiving CHPP, and this rate is significantly higher than the rates in P2 and P3 patients who did not receive CHPP. The complications of CHPP with administration of anticancer drugs were mild bone marrow suppression in two (25 percent) of the eight patients and also a mild grade of renal dysfunction in one (12.5 percent), though not lethal. The results suggest that the combination of CHPP with the administration of anticancer drugs is a safe and effective therapy for peritoneal dissemination of colorectal cancers.

Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Colorectal Neoplasms; Female; Humans; Hyperthermia, Induced; Male; Middle Aged; Mitomycin; Organoplatinum Compounds; Peritoneal Neoplasms; Survival Analysis

1992