dideoxyadenosine has been researched along with HIV in 44 studies
*HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (47.73) | 18.7374 |
| 1990's | 18 (40.91) | 18.2507 |
| 2000's | 5 (11.36) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aoki, S; Barchi, JJ; Driscoll, JS; Ford, H; Kelley, JA; Marquez, VE; Mitsuya, H; Shirasaka, T | 1 |
| Aoki, S; Broder, S; Driscoll, JS; Ford, H; Johns, DG; Kelley, JA; Marquez, VE; Mitsuya, H; Roth, JS; Tseng, CK | 1 |
| Clement, J; Erickson, J; Hayashi, S; Herrin, T; Kern, E; Norbeck, DW; Plattner, JJ; Rosenbrook, W; Sham, H; Swanson, R | 1 |
| Ahn, SK; Beach, JW; Chu, CK; Doboszewski, B; Jeong, LS; Lin, ZX; Schinazi, RF; Ullas, GV | 1 |
| Rosowsky, A; Ruprecht, RM; Sodroski, JG; Solan, VC | 1 |
| Abushanab, E; Sarma, MS | 1 |
| Broder, S; Driscoll, JS; Kim, CH; Marquez, VE; Mitsuya, H | 1 |
| Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R | 1 |
| Eriksson, S; Gosselin, G; Imbach, JL; Maury, G; Pélicano, H; Pierra, C | 1 |
| Boryski, J; Collu, G; Kraszewski, A; La Colla, P; Loddo, R; Romanowska, J; Sanna, G; Secci, B; Stawiński, J; Szymańska-Michalak, A | 1 |
| Costanzi, S; Cristalli, G; Lambertucci, C; Salvatori, D; Vincenzetti, S; Vita, A; Vittori, S; Volpini, R | 1 |
| Condreay, LD; Daluge, SM; Gudmundsson, KS; Hazen, R; Jansen, R; Johnson, LC; McGuigan, C | 1 |
| Ahluwalia, GS; Cooney, DA; Driscoll, JS; Johns, DG; Mitsuya, H; Shirasaka, T | 1 |
| Aubertin, AM; Benzaria, S; Girardet, JL; Gosselin, G; Imbach, JL; Kirn, A; Maury, G; Pelicano, H; Perigaud, C | 1 |
| Baker, CJ; Bremer, JW; Dimitrov, DH; Doyle, M; Hollinger, FB; Kline, MW; Shearer, WT | 1 |
| Donzanti, BA; Driscoll, JS; Kelley, JA; Placke, M; Roth, JS; Singer, A; Tomaszewski, JE; Tosca, P; Yarrington, JT | 1 |
| Aquaro, S; Balzarini, J; De Clercq, E; Heijtink, R; Kruining, J; McGuigan, C; Naesens, L; Pannecouque, C; Perno, CF; Wedgwood, O; Witvrouw, M | 1 |
| Ford, H; Kelley, JA; Mitsuya, H; Roth, JS; Tanaka, M | 1 |
| Cretton-Scott, E; el Kouni, MH; Gosselin, G; Imbach, JL; Pierra, C; Placidi, L; Schinazi, RF; Sommadossi, JP | 1 |
| Bryant, ML; Cretton-Scott, E; Egron, D; el Kouni, MH; Faraj, A; Gosseli, G; Imbach, JL; Loi, AG; Martin, LT; Périgaud, C; Pierra, C; Placidi, L; Schinazi, RF; Sommadossi, JP | 1 |
| Nair, V; Sells, TB | 1 |
| Ahluwalia, GS; Broder, S; Cooney, DA; Fridland, A; Hartman, NR; Johns, DG; Kageyama, S; Mitsuya, H | 1 |
| Connell, EV; Frank, KB; Holman, MJ; Huryn, DM; Mitsuya, H; Richman, DD; Sluboski, BC; Tam, SY; Todaro, LJ; Weigele, M | 1 |
| Gao, YG; Liaw, YC; Marquez, VE; Wang, AH | 1 |
| Chedid, L; Lange, W; Masihi, KN; Rohde-Schulz, B | 1 |
| Balzarini, J; De Clercq, E; Naesens, L; Robins, MJ | 1 |
| Hua, M; Vince, R | 1 |
| Broder, S; DeVico, AL; Di Marzo Veronese, F; Jarrett, RF; Johns, DG; Matsukura, M; Mitsuya, H; Reitz, MS; Sarngadharan, MG | 1 |
| Klunk, LJ; Russell, JW | 1 |
| Blair, PC; Fort, MM; Fuchs, BA; Germolec, DR; Luster, MI; McCay, JA; Munson, AE; Thompson, M; Tomaszewski, JE; White, KL | 1 |
| Agarwal, RP; Busso, ME; Mian, AM; Resnick, L | 1 |
| Carrera, CJ; Carson, DA; Haertle, T; Richman, DD; Wasson, DB; Willis, EH | 1 |
| Carson, DA; Kornbluth, RS; Richman, DD | 1 |
| Broder, S; Mitsuya, H | 1 |
| Cooney, DA; Gartner, S; Gerrard, TL; Hao, Z; Hartman, NR; Johns, DG; Perno, CF; Popovic, M; Wilson, YA; Yarchoan, R | 1 |
| Ahluwalia, G; Balzarini, J; Broder, S; Cooney, DA; Dalal, M; Fridland, A; Hao, Z; Johns, DG; Johnson, M; Mitsuya, H | 1 |
| Baba, M; Balzarini, J; de Clercq, E; Herdewijn, P; Pauwels, R; Robins, MJ; Wood, SG | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Desmyter, J; Herdewijn, P; Madej, D; Pauwels, R; Robins, MJ; Zou, RM | 1 |
| Carrera, CJ; Carson, DA; Haertle, T; Richman, DD; Sowers, LC; Wasson, DB | 1 |
| Carson, DA; Wasson, DB | 1 |
| Ahluwalia, G; Broder, S; Connelly, MC; Cooney, DA; Fridland, A; Johns, DG; Johnson, MA | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R; Robins, MJ; Zou, RM | 1 |
| Balzarini, J; De Clercq, E; Herdewijn, P; Robins, MJ; Zou, RM | 1 |
1 review(s) available for dideoxyadenosine and HIV
| Article | Year |
|---|---|
Anabolism and mechanism of action of Ro24-5098, an isomer of 2',3'-dideoxyadenosine (ddA) with anti-HIV activity.
Topics: Antiviral Agents; Dideoxyadenosine; HIV; Humans; Isomerism; Reverse Transcriptase Inhibitors | 1990 |
43 other study(ies) available for dideoxyadenosine and HIV
| Article | Year |
|---|---|
Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs.
Topics: Adenosine Deaminase; Antiviral Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Kinetics; Prodrugs; Structure-Activity Relationship | 1991 |
Acid-stable 2'-fluoro purine dideoxynucleosides as active agents against HIV.
Topics: Antiviral Agents; Drug Stability; Gene Products, gag; HIV; HIV Core Protein p24; Lymphocyte Activation; Purine Nucleosides; Viral Core Proteins | 1990 |
Cyclobut-A and cyclobut-G: broad-spectrum antiviral agents with potential utility for the therapy of AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Animals; Antiviral Agents; Guanine; Herpesviridae; HIV; Humans; Mice; Microbial Sensitivity Tests | 1990 |
Synthesis and structure-activity relationships of 6-substituted 2',3'-dideoxypurine nucleosides as potential anti-human immunodeficiency virus agents.
Topics: Antiviral Agents; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; Microbial Sensitivity Tests; Structure-Activity Relationship | 1990 |
Synthesis of the 2-chloro analogues of 3'-deoxyadenosine, 2',3'-dideoxyadenosine, and 2',3'-didehydro-2',3'-dideoxyadenosine as potential antiviral agents.
Topics: 2-Chloroadenosine; Animals; Antiviral Agents; Deoxyadenosines; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; Mice; Structure-Activity Relationship | 1989 |
1',2'-seco-dideoxynucleosides as potential anti-HIV agents.
Topics: Antiviral Agents; Chemical Phenomena; Chemistry; Dideoxynucleosides; HIV | 1989 |
Potential anti-AIDS drugs. 2',3'-Dideoxycytidine analogues.
Topics: Acquired Immunodeficiency Syndrome; Cell Line; Chemical Phenomena; Chemistry; Deoxycytidine; HIV; Structure-Activity Relationship; T-Lymphocytes, Helper-Inducer; Zalcitabine | 1987 |
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication | 1987 |
Synthesis and anti-HIV activity of various 2'- and 3'-substituted 2',3'-dideoxyadenosines: a structure-activity analysis.
Topics: Antiviral Agents; Deoxyadenosines; Dideoxyadenosine; HIV; Structure-Activity Relationship | 1987 |
Enzymatic properties of the unnatural beta-L-enantiomers of 2',3'-dideoxyadenosine and 2',3'-didehydro-2',3'-dideoxyadenosine.
Topics: Adenosine Deaminase; Adenosine Kinase; Animals; Anti-HIV Agents; Antiviral Agents; Cattle; Deoxycytidine Kinase; Dideoxyadenosine; Drug Stability; Hepatitis B virus; HIV; Humans; Purine-Nucleoside Phosphorylase; Stereoisomerism; Structure-Activity Relationship | 1997 |
Aryl nucleoside H-phosphonates. Part 16: synthesis and anti-HIV-1 activity of di-aryl nucleoside phosphotriesters.
Topics: Anti-HIV Agents; Cell Line; Cells, Cultured; HIV; Humans; Hydroxy Acids; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Nucleotides; Organophosphonates; Virus Replication | 2009 |
Adenine and deazaadenine nucleoside and deoxynucleoside analogues: inhibition of viral replication of sheep MVV (in vitro model for HIV) and bovine BHV-1.
Topics: Animals; Cattle; Cell Line; Cell Survival; Dideoxyadenosine; Herpesvirus 1, Bovine; HIV; Sheep; Structure-Activity Relationship; Tubercidin; Virus Replication; Visna-maedi virus | 2002 |
Phosphoramidate protides of 2',3'-dideoxy-3'-fluoroadenosine and related nucleosides with potent activity against HIV and HBV.
Topics: Amides; Antiviral Agents; Cell Line, Tumor; Deoxyadenosines; Dideoxyadenosine; Hepatitis B virus; HIV; Humans; Inhibitory Concentration 50; Lymphocytes; Molecular Structure; Phosphoric Acids | 2003 |
Enhancement by 2'-deoxycoformycin of the 5'-phosphorylation and anti-human immunodeficiency virus activity of 2',3'-dideoxyadenosine and 2'-beta-fluoro-2',3'-dideoxyadenosine.
Topics: Adenosine Deaminase Inhibitors; Cell Line; Didanosine; Dideoxyadenosine; Drug Synergism; HIV; IMP Dehydrogenase; Pentostatin; Phosphorylation; Ribavirin | 1994 |
Equal inhibition of the replication of human immunodeficiency virus in human T-cell culture by ddA bis(SATE)phosphotriester and 3'-azido-2',3'-dideoxythymidine.
Topics: Antiviral Agents; Cell Line; Dideoxyadenosine; Drug Evaluation, Preclinical; HIV; Humans; T-Lymphocytes; Virus Replication; Zidovudine | 1994 |
Study of human immunodeficiency virus resistance to 2'-3'-dideoxyinosine and zidovudine in sequential isolates from pediatric patients on long-term therapy.
Topics: Child; Child, Preschool; Dideoxyadenosine; Drug Resistance, Microbial; Female; HIV; HIV Seropositivity; Humans; Infant; Male; Zidovudine | 1993 |
Acute cardiotoxicity of the Anti-HIV dideoxynucleoside, F-ddA, in the rat.
Topics: Administration, Oral; Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Dideoxyadenosine; Female; Heart Diseases; HIV; Injections, Intravenous; Myocardium; Rats; Rats, Sprague-Dawley | 1995 |
Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.
Topics: Adenosine Monophosphate; Alanine; Animals; Anti-HIV Agents; Antiviral Agents; Cell Line; Cells, Cultured; Dideoxyadenosine; Hepatitis B virus; HIV; Humans; Leukocytes, Mononuclear; Macrophages; Molecular Structure; Moloney murine sarcoma virus; Simian Immunodeficiency Virus; Transfection; Tumor Cells, Cultured | 1997 |
Determination of 2'-beta-fluoro-2',3'-dideoxyadenosine, an experimental anti-AIDS drug, in human plasma by high-performance liquid chromatography.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Blood Proteins; Chromatography, High Pressure Liquid; Dideoxyadenosine; Drug Stability; HIV; HIV Seropositivity; Humans; Protein Binding; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1998 |
Intracellular metabolism of beta-L-2',3'-dideoxyadenosine: relevance to its limited antiviral activity.
Topics: Adenosine; Antiviral Agents; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Cryopreservation; Dideoxyadenosine; Hepatitis B virus; HIV; Humans; Liver; Monocytes; Thionucleosides | 2000 |
Antiviral activity and intracellular metabolism of bis(tButylSATE) phosphotriester of beta-L-2',3'dideoxyadenosine, a potent inhibitor of HIV and HBV replication.
Topics: Animals; Anti-HIV Agents; Antiviral Agents; Chromatography, High Pressure Liquid; Dideoxyadenosine; Dideoxynucleotides; DNA-Directed DNA Polymerase; Half-Life; Hematopoietic Stem Cells; Hepatitis B virus; Hepatocytes; HIV; Humans; Inhibitory Concentration 50; Lamivudine; Leukocytes, Mononuclear; Marmota; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Tumor Cells, Cultured; Virus Replication | 2001 |
Interpretation of the roles of adenylosuccinate lyase and of AMP deaminase in the anti-HIV activity of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
Topics: Adenosine; Adenylosuccinate Lyase; AMP Deaminase; Deoxyadenine Nucleotides; Didanosine; Dideoxyadenosine; Dideoxynucleotides; HIV; Succinates | 1992 |
Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the anti-human immunodeficiency virus nucleosides 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
Topics: Antiviral Agents; Cells, Cultured; Chromatography; Didanosine; Dideoxyadenosine; Drug Synergism; HIV; Humans; IMP Dehydrogenase; Inosine; Inosine Monophosphate; Nucleotides; Phosphorylation; Ribavirin; Stimulation, Chemical | 1991 |
Molecular structures of two new anti-HIV nucleoside analogs: 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)adenine and 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)hypoxanthine.
Topics: Antiviral Agents; Didanosine; Dideoxyadenosine; Dideoxynucleosides; HIV; Molecular Structure; Structure-Activity Relationship; X-Ray Diffraction | 1992 |
Muramyl dipeptide inhibits replication of human immunodeficiency virus in vitro.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Cells, Cultured; Colony-Stimulating Factors; Dideoxyadenosine; Gene Products, gag; HIV; HIV Core Protein p24; Humans; Viral Core Proteins; Virus Replication | 1990 |
Potentiating effect of ribavirin on the in vitro and in vivo antiretrovirus activities of 2',3'-dideoxyinosine and 2',3'-dideoxy-2,6-diaminopurine riboside.
Topics: Animals; Antiviral Agents; Cell Line; Cell Transformation, Viral; Cytopathogenic Effect, Viral; Didanosine; Dideoxyadenosine; Drug Synergism; Fibroblasts; HIV; Humans; Mice; Mice, Inbred Strains; Moloney murine sarcoma virus; Ribavirin; Sarcoma, Experimental; Virus Replication | 1990 |
Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides.
Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Dideoxyadenosine; Dideoxynucleosides; HIV; Leukemia P388; Molecular Structure; Purine Nucleosides; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Replication; Zidovudine | 1990 |
Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in vitro.
Topics: Antiviral Agents; Base Sequence; Cell Line; Deoxyadenosines; Deoxycytidine; Dideoxyadenosine; DNA Replication; HIV; Humans; RNA-Directed DNA Polymerase; RNA, Messenger; T-Lymphocytes; Transcription, Genetic; Zalcitabine | 1987 |
Comparative pharmacokinetics of new anti-HIV agents: 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
Topics: Animals; Antiviral Agents; Biological Availability; Didanosine; Dideoxyadenosine; Dideoxynucleosides; HIV; Male; Mice; Mice, Inbred ICR | 1989 |
A comparison of three nucleoside analogs with anti-retroviral activity on immune and hematopoietic functions in mice: in vitro toxicity to precursor cells and microstromal environment.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antigen-Antibody Reactions; Antiviral Agents; Bone Marrow; Dideoxyadenosine; Female; Hematopoiesis; HIV; Immunity, Cellular; Macrophages; Mice; Mice, Inbred C57BL; Spleen; Stem Cells; T-Lymphocytes; Virus Replication; Zalcitabine; Zidovudine | 1989 |
Uptake of 2',3'-dideoxyadenosine in human immunodeficiency virus-infected and noninfected human cells.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cell Line; Deoxyadenosines; Dideoxyadenosine; Diffusion; HIV; Humans; Nucleosides; Osmolar Concentration; Pentostatin; Temperature; Thioinosine | 1989 |
2-halo-2',3'-dideoxyadenosines: metabolically stable dideoxynucleosides with activity against the human immunodeficiency virus (HIV).
Topics: Antiviral Agents; Dideoxyadenosine; Drug Evaluation, Preclinical; HIV; Humans; T-Lymphocytes | 1989 |
Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages.
Topics: Adenosine Kinase; Cell Line; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Dideoxyadenosine; HIV; Humans; Macrophages; Phosphorylation; T-Lymphocytes; Thymidine; Thymidine Kinase; Uridine Kinase; Virus Replication; Zalcitabine; Zidovudine | 1987 |
Inhibition of infectivity and replication of HIV-2 and SIV in helper T-cells by 2',3'-dideoxynucleosides in vitro.
Topics: Cytopathogenic Effect, Viral; Deoxyadenosines; Deoxycytidine; Dideoxyadenosine; HIV; In Vitro Techniques; Nucleosides; Retroviridae; T-Lymphocytes, Helper-Inducer; Thymidine; Viral Proteins; Virus Replication; Zalcitabine; Zidovudine | 1988 |
Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides.
Topics: Antiviral Agents; Deoxycytidine Kinase; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; In Vitro Techniques; Macrophages; Monocytes; Phosphorylation; Thymidine Kinase; Time Factors; Virus Replication; Zalcitabine; Zidovudine | 1988 |
Initial studies on the cellular pharmacology of 2',3'-dideoxyadenosine, an inhibitor of HTLV-III infectivity.
Topics: Adenosine Deaminase; Animals; Antiviral Agents; Cell Line; Deoxyadenosines; Dideoxyadenosine; HIV; Humans; Leukemia P388; Purine-Nucleoside Phosphorylase | 1987 |
Potent and selective activity of 3'-azido-2,6-diaminopurine-2',3'-dideoxyriboside, 3'-fluoro-2,6-diaminopurine-2',3'-dideoxyriboside, and 3'-fluoro-2',3'-dideoxyguanosine against human immunodeficiency virus.
Topics: Adenosine Deaminase; Antimetabolites; Antiviral Agents; Coformycin; Deoxyadenosines; Deoxyguanosine; Dideoxyadenosine; Dideoxynucleosides; HIV; Pentostatin; Prodrugs; Solubility; Virus Replication | 1988 |
Investigations on the anti-HIV activity of 2',3'-dideoxyadenosine analogues with modifications in either the pentose or purine moiety. Potent and selective anti-HIV activity of 2,6-diaminopurine 2',3'-dideoxyriboside.
Topics: Adenosine Deaminase; Animals; Antiviral Agents; Cell Line; Deamination; Deoxyadenosines; Dideoxyadenosine; HIV; Humans; Mice; Moloney murine sarcoma virus; Structure-Activity Relationship; Tumor Cells, Cultured | 1988 |
Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2',3'-dideoxyadenosine derivatives.
Topics: Adenosine Deaminase Inhibitors; AMP Deaminase; Cell Line; Coformycin; Deoxyadenosines; Deoxycytidine Kinase; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; Phosphorylation; T-Lymphocytes; Virus Replication | 1988 |
Synthesis of 2',3'-dideoxynucleosides by enzymatic trans-glycosylation.
Topics: Antiviral Agents; Deoxyadenosines; Deoxyribonucleosides; Dideoxyadenosine; Glycosylation; HIV; Kinetics; Lactobacillus; Pentosyltransferases; Substrate Specificity | 1988 |
Metabolic pathways for the activation of the antiretroviral agent 2',3'-dideoxyadenosine in human lymphoid cells.
Topics: Adenosine Kinase; Antiviral Agents; Cell Line; Chromatography, High Pressure Liquid; Deoxycytidine Kinase; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; Kinetics; Virus Replication | 1988 |
The 2',3'-dideoxyriboside of 2,6-diaminopurine selectively inhibits human immunodeficiency virus (HIV) replication in vitro.
Topics: Adenosine Deaminase Inhibitors; Animals; Antigens, Viral; Antiviral Agents; Cell Line; Cell Transformation, Viral; Deoxyadenosines; Dideoxyadenosine; DNA Replication; HIV; HIV Antigens; Humans; Virus Replication | 1987 |
The 2',3'-dideoxyriboside of 2,6-diaminopurine and its 2',3'-didehydro derivative inhibit the deamination of 2',3'-dideoxyadenosine, an inhibitor of human immunodeficiency virus (HIV) replication.
Topics: Adenosine Deaminase; Animals; Cattle; Deoxyadenosines; Dideoxyadenosine; Dideoxynucleosides; DNA Replication; HIV; Intestines; Kinetics; Nucleoside Deaminases; Substrate Specificity; Virus Replication | 1987 |