Page last updated: 2024-10-26

dicyclomine and Spasm

dicyclomine has been researched along with Spasm in 6 studies

Dicyclomine: A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.
dicyclomine : The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.

Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"The case of a 43-year-old woman with persistent anal fissure responsive to dicyclomine is described."7.68Dicyclomine for medical management of persistent anal fissure with associated spasm of the internal sphincter. ( Brown, EB; Miller, LG; Perkins, G; Rogers, JC, 1992)
" Dicyclomine is a muscarinic antagonist receptor that relieves the smooth muscle spasm of the gastrointestinal tract and affects the cardiovascular system."3.88Inhibitory action of dicyclomine on lipase activity, kinetics and molecular study. ( Fazilati, M; Minai-Tehrani, A; Minai-Tehrani, D; Talebi, M, 2018)
"The case of a 43-year-old woman with persistent anal fissure responsive to dicyclomine is described."3.68Dicyclomine for medical management of persistent anal fissure with associated spasm of the internal sphincter. ( Brown, EB; Miller, LG; Perkins, G; Rogers, JC, 1992)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Hussain Shah, SA1
Aleem, A1
Talebi, M1
Minai-Tehrani, D1
Fazilati, M1
Minai-Tehrani, A1
Rehman, NU1
Mehmood, MH1
Alkharfy, KM1
Gilani, AH1
MARIEN, B1
WEBSTER, DR1
TIDMARSH, CJ1
Thompson, IM1
Lauvetz, R1
Miller, LG1
Rogers, JC1
Brown, EB1
Perkins, G1

Trials

1 trial available for dicyclomine and Spasm

ArticleYear
Oxybutynin in bladder spasm, neurogenic bladder, and enuresis.
    Urology, 1976, Volume: 8, Issue:5

    Topics: Adult; Amines; Bethanechol Compounds; Child; Clinical Trials as Topic; Dicyclomine; Enuresis; Humans

1976

Other Studies

5 other studies available for dicyclomine and Spasm

ArticleYear
Investigations of plausible pharmacodynamics supporting the antispasmodic, bronchodilator, and antidiarrheal activities of Berberis lycium Royle. Via in silico, in vitro, and in vivo studies.
    Journal of ethnopharmacology, 2023, Apr-06, Volume: 305

    Topics: Animals; Antidiarrheals; Berberis; Bronchodilator Agents; Carbachol; Castor Oil; Cough; Diarrhea; Di

2023
Inhibitory action of dicyclomine on lipase activity, kinetics and molecular study.
    International journal of biological macromolecules, 2018, Volume: 107, Issue:Pt B

    Topics: Cardiovascular System; Dicyclomine; Gastrointestinal Tract; Humans; Hydrogen Bonding; Hydrophobic an

2018
Studies on antidiarrheal and antispasmodic activities of Lepidium sativum crude extract in rats.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:1

    Topics: Abdominal Pain; Animals; Antidiarrheals; Calcium Channel Blockers; Castor Oil; Diarrhea; Dicyclomine

2012
The effect of bentyl hydrochloride on morphine-induced spasm of the sphincter of Oddi in man; a preliminary report.
    Gastroenterology, 1953, Volume: 24, Issue:2

    Topics: Bile Ducts; Common Bile Duct; Dicyclomine; Humans; Male; Morphine; Muscle Relaxants, Central; Spasm;

1953
Dicyclomine for medical management of persistent anal fissure with associated spasm of the internal sphincter.
    Texas medicine, 1992, Volume: 88, Issue:11

    Topics: Adult; Dicyclomine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fissure

1992