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dicyclomine and Nerve Degeneration

dicyclomine has been researched along with Nerve Degeneration in 1 studies

Dicyclomine: A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.
dicyclomine : The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"Dicyclomine treatment produced decreases of 38% (p = 0."1.35Dicyclomine, an M1 muscarinic antagonist, reduces biomarker levels, but not neuronal degeneration, in fluid percussion brain injury. ( Cox, CD; Hayes, RL; Liu, MC; Lyeth, BG; Wang, KK; West, EJ, 2008)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cox, CD1
West, EJ1
Liu, MC1
Wang, KK1
Hayes, RL1
Lyeth, BG1

Other Studies

1 other study available for dicyclomine and Nerve Degeneration

ArticleYear
Dicyclomine, an M1 muscarinic antagonist, reduces biomarker levels, but not neuronal degeneration, in fluid percussion brain injury.
    Journal of neurotrauma, 2008, Volume: 25, Issue:11

    Topics: Animals; Biomarkers; Blotting, Western; Brain Injuries; Calpain; Caspases; Cell Death; Dicyclomine;

2008