dicyclomine has been researched along with Heart Defects, Congenital in 8 studies
Dicyclomine: A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.
dicyclomine : The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.
Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One of twins was born with prune belly syndrome and congenital heart defect following exposure to Bendectin and Tigan." | 1.27 | Prune belly syndrome and heart defect in one of monozygotic twins, following exposure to Tigan and Bendectin. ( Greene, C; Shapira, E; Wilson, A, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koren, G | 1 |
| Eskenazi, B | 1 |
| Bracken, MB | 1 |
| Mitchell, AA | 1 |
| Rosenberg, L | 1 |
| Shapiro, S | 1 |
| Slone, D | 1 |
| Check, WA | 1 |
| Shiono, PH | 1 |
| Klebanoff, MA | 1 |
| Zierler, S | 1 |
| Rothman, KJ | 1 |
| Hendrickx, AG | 1 |
| Cukierski, M | 1 |
| Prahalada, S | 1 |
| Janos, G | 1 |
| Rowland, J | 1 |
| Greene, C | 1 |
| Wilson, A | 1 |
| Shapira, E | 1 |
8 other studies available for dicyclomine and Heart Defects, Congenital
| Article | Year |
|---|---|
Treating morning sickness in the United States--changes in prescribing are needed.
Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Female; Heart Defects, Conge | 2014 |
Bendectin (Debendox) as a risk factor for pyloric stenosis.
Topics: Abnormalities, Drug-Induced; Adult; Dicyclomine; Doxylamine; Drug Combinations; Female; Heart Defect | 1982 |
Birth defects related to bendectin use in pregnancy. I. Oral clefts and cardiac defects.
Topics: Antiemetics; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Drug Combinations; Drug Evaluation; F | 1981 |
CDC study: no evidence for teratogenicity of Bendectin.
Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Heart | 1979 |
Bendectin and human congenital malformations.
Topics: Abnormalities, Drug-Induced; Central Nervous System; Dicyclomine; Digestive System Abnormalities; Do | 1989 |
Congenital heart disease in relation to maternal use of Bendectin and other drugs in early pregnancy.
Topics: Acetaminophen; Adult; Anti-Bacterial Agents; Antiemetics; Aspirin; Dicyclomine; Doxylamine; Drug Com | 1985 |
Evaluation of bendectin embryotoxicity in nonhuman primates: I. Ventricular septal defects in prenatal macaques and baboon.
Topics: Animals; Dicyclomine; Dose-Response Relationship, Drug; Doxylamine; Drug Combinations; Female; Fetus | 1985 |
Prune belly syndrome and heart defect in one of monozygotic twins, following exposure to Tigan and Bendectin.
Topics: Benzamides; Dicyclomine; Doxylamine; Drug Combinations; Heart Defects, Congenital; Humans; Prune Bel | 1985 |