dicyclomine has been researched along with Delayed Effects, Prenatal Exposure in 8 studies
Dicyclomine: A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.
dicyclomine : The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Incidence rates of colorectal cancer (CRC) are increasing among adults born in and after the 1960s, implicating pregnancy-related exposures introduced at that time as risk factors." | 3.01 | In utero exposure to antiemetic and risk of adult-onset colorectal cancer. ( Cirillo, PM; Cohn, BA; Krigbaum, NY; Murphy, CC; Singal, AG, 2023) |
| "81 and a dose-response relationship was noted (P = 0." | 2.66 | Maternal drug use and risk of childhood nonlymphoblastic leukemia among offspring. An epidemiologic investigation implicating marijuana (a report from the Childrens Cancer Study Group). ( Arthur, DC; Benjamin, D; Buckley, JD; Daigle, AE; Hammond, GD; Robison, LL; Wells, R, 1989) |
| " No dose-response relationship was evident." | 1.27 | Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): childhood cancer and the consumption of debendox and related drugs in pregnancy. ( Birch, JM; Cartwright, RA; Hartley, AL; Hopton, PA; Johnston, HE; Mann, JR; McKinney, PA; Stiller, CA; Waterhouse, JA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Murphy, CC | 1 |
| Cirillo, PM | 1 |
| Krigbaum, NY | 1 |
| Singal, AG | 1 |
| Cohn, BA | 1 |
| Hill, LM | 1 |
| Kleinberg, F | 1 |
| Aselton, P | 1 |
| Jick, H | 1 |
| Chentow, SJ | 1 |
| Perera, DR | 1 |
| Hunter, JR | 1 |
| Rothman, KJ | 1 |
| Correy, JF | 1 |
| Newman, NM | 1 |
| Collins, JA | 1 |
| Burrows, EA | 1 |
| Burrows, RF | 1 |
| Curran, JT | 1 |
| Robison, LL | 1 |
| Buckley, JD | 1 |
| Daigle, AE | 1 |
| Wells, R | 1 |
| Benjamin, D | 1 |
| Arthur, DC | 1 |
| Hammond, GD | 1 |
| Kiley, VA | 1 |
| Lazerson, J | 1 |
| Elbourne, D | 1 |
| Mutch, L | 1 |
| McKinney, PA | 1 |
| Cartwright, RA | 1 |
| Stiller, CA | 1 |
| Hopton, PA | 1 |
| Mann, JR | 1 |
| Birch, JM | 1 |
| Hartley, AL | 1 |
| Waterhouse, JA | 1 |
| Johnston, HE | 1 |
2 reviews available for dicyclomine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
In utero exposure to antiemetic and risk of adult-onset colorectal cancer.
Topics: Adult; Antiemetics; Colorectal Neoplasms; Dicyclomine; Female; Humans; Mothers; Pregnancy; Prenatal | 2023 |
Effects of drugs and chemicals on the fetus and newborn (1).
Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Behavior; Caffeine; Dicyclomine; Doxylamine; Drug | 1984 |
1 trial available for dicyclomine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Maternal drug use and risk of childhood nonlymphoblastic leukemia among offspring. An epidemiologic investigation implicating marijuana (a report from the Childrens Cancer Study Group).
Topics: Adolescent; Age Factors; Antiemetics; Child; Child, Preschool; Dicyclomine; Doxylamine; Drug Combina | 1989 |
5 other studies available for dicyclomine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Pyloric stenosis and maternal Bendectin exposure.
Topics: Adult; Dicyclomine; Doxylamine; Drug Combinations; Drug Prescriptions; Female; Follow-Up Studies; Hu | 1984 |
Use of prescription drugs in the first trimester and congenital malformations.
Topics: Abnormalities, Drug-Induced; Aspirin; Contraceptives, Oral; Dicyclomine; Female; Humans; Infant, New | 1991 |
Agenesis of the corpus callosum and neural crest tumors.
Topics: Abdominal Neoplasms; Abnormalities, Drug-Induced; Agenesis of Corpus Callosum; Child; Child, Prescho | 1986 |
Debendox.
Topics: Abnormalities, Drug-Induced; Antiemetics; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Drug Com | 1986 |
Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): childhood cancer and the consumption of debendox and related drugs in pregnancy.
Topics: Adolescent; Antiemetics; Child; Cyclohexanecarboxylic Acids; Dicyclomine; Dose-Response Relationship | 1985 |