Page last updated: 2024-10-26

dicyclomine and Delayed Effects, Prenatal Exposure

dicyclomine has been researched along with Delayed Effects, Prenatal Exposure in 8 studies

Dicyclomine: A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.
dicyclomine : The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.

Research Excerpts

ExcerptRelevanceReference
"Incidence rates of colorectal cancer (CRC) are increasing among adults born in and after the 1960s, implicating pregnancy-related exposures introduced at that time as risk factors."3.01In utero exposure to antiemetic and risk of adult-onset colorectal cancer. ( Cirillo, PM; Cohn, BA; Krigbaum, NY; Murphy, CC; Singal, AG, 2023)
"81 and a dose-response relationship was noted (P = 0."2.66Maternal drug use and risk of childhood nonlymphoblastic leukemia among offspring. An epidemiologic investigation implicating marijuana (a report from the Childrens Cancer Study Group). ( Arthur, DC; Benjamin, D; Buckley, JD; Daigle, AE; Hammond, GD; Robison, LL; Wells, R, 1989)
" No dose-response relationship was evident."1.27Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): childhood cancer and the consumption of debendox and related drugs in pregnancy. ( Birch, JM; Cartwright, RA; Hartley, AL; Hopton, PA; Johnston, HE; Mann, JR; McKinney, PA; Stiller, CA; Waterhouse, JA, 1985)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Murphy, CC1
Cirillo, PM1
Krigbaum, NY1
Singal, AG1
Cohn, BA1
Hill, LM1
Kleinberg, F1
Aselton, P1
Jick, H1
Chentow, SJ1
Perera, DR1
Hunter, JR1
Rothman, KJ1
Correy, JF1
Newman, NM1
Collins, JA1
Burrows, EA1
Burrows, RF1
Curran, JT1
Robison, LL1
Buckley, JD1
Daigle, AE1
Wells, R1
Benjamin, D1
Arthur, DC1
Hammond, GD1
Kiley, VA1
Lazerson, J1
Elbourne, D1
Mutch, L1
McKinney, PA1
Cartwright, RA1
Stiller, CA1
Hopton, PA1
Mann, JR1
Birch, JM1
Hartley, AL1
Waterhouse, JA1
Johnston, HE1

Reviews

2 reviews available for dicyclomine and Delayed Effects, Prenatal Exposure

ArticleYear
In utero exposure to antiemetic and risk of adult-onset colorectal cancer.
    JNCI cancer spectrum, 2023, 03-01, Volume: 7, Issue:2

    Topics: Adult; Antiemetics; Colorectal Neoplasms; Dicyclomine; Female; Humans; Mothers; Pregnancy; Prenatal

2023
Effects of drugs and chemicals on the fetus and newborn (1).
    Mayo Clinic proceedings, 1984, Volume: 59, Issue:10

    Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Behavior; Caffeine; Dicyclomine; Doxylamine; Drug

1984

Trials

1 trial available for dicyclomine and Delayed Effects, Prenatal Exposure

ArticleYear
Maternal drug use and risk of childhood nonlymphoblastic leukemia among offspring. An epidemiologic investigation implicating marijuana (a report from the Childrens Cancer Study Group).
    Cancer, 1989, May-15, Volume: 63, Issue:10

    Topics: Adolescent; Age Factors; Antiemetics; Child; Child, Preschool; Dicyclomine; Doxylamine; Drug Combina

1989

Other Studies

5 other studies available for dicyclomine and Delayed Effects, Prenatal Exposure

ArticleYear
Pyloric stenosis and maternal Bendectin exposure.
    American journal of epidemiology, 1984, Volume: 120, Issue:2

    Topics: Adult; Dicyclomine; Doxylamine; Drug Combinations; Drug Prescriptions; Female; Follow-Up Studies; Hu

1984
Use of prescription drugs in the first trimester and congenital malformations.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1991, Volume: 31, Issue:4

    Topics: Abnormalities, Drug-Induced; Aspirin; Contraceptives, Oral; Dicyclomine; Female; Humans; Infant, New

1991
Agenesis of the corpus callosum and neural crest tumors.
    Pediatric hematology and oncology, 1986, Volume: 3, Issue:2

    Topics: Abdominal Neoplasms; Abnormalities, Drug-Induced; Agenesis of Corpus Callosum; Child; Child, Prescho

1986
Debendox.
    The Medical journal of Australia, 1986, Mar-03, Volume: 144, Issue:5

    Topics: Abnormalities, Drug-Induced; Antiemetics; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Drug Com

1986
Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): childhood cancer and the consumption of debendox and related drugs in pregnancy.
    British journal of cancer, 1985, Volume: 52, Issue:6

    Topics: Adolescent; Antiemetics; Child; Cyclohexanecarboxylic Acids; Dicyclomine; Dose-Response Relationship

1985