dicyclomine has been researched along with Congenital Limb Deformities in 6 studies
Dicyclomine: A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.
dicyclomine : The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antinausea drug combination, doxylamine/dicyclomine/pyridoxine (Debendox or Bendectin [US] ), has been withdrawn from the market because of litigation based upon charges that it causes congenital limb defects." | 3.67 | The innocent bystander. Doxylamine/dicyclomine/pyridoxine and congenital limb defects. ( Elliott, J; Forrest, J; Kricker, A; McCredie, J, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCredie, J | 1 |
| Kricker, A | 1 |
| Elliott, J | 1 |
| Forrest, J | 1 |
| Cordero, JF | 1 |
| Oakley, GP | 1 |
| Greenberg, F | 1 |
| James, LM | 1 |
| Correy, JF | 2 |
| Newman, NM | 2 |
6 other studies available for dicyclomine and Congenital Limb Deformities
| Article | Year |
|---|---|
The innocent bystander. Doxylamine/dicyclomine/pyridoxine and congenital limb defects.
Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Dose-Response Relationship, Drug; Doxylamine; | 1984 |
Is Bendectin a teratogen?
Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Drug Evaluatio | 1981 |
Debendox and limb reduction deformities.
Topics: Abnormalities, Drug-Induced; Australia; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug C | 1981 |
Criteria for science in the courts.
Topics: Dicyclomine; Doxylamine; Drug Combinations; Expert Testimony; Humans; Jurisprudence; Limb Deformitie | 1993 |
Fetal malformation after Debendox treatment in early pregnancy.
Topics: Abnormalities, Drug-Induced; Antiemetics; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug | 1978 |
Limb-reduction deformities and Debendox.
Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, New | 1987 |