dicyclomine has been researched along with Brain Injuries in 2 studies
Dicyclomine: A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.
dicyclomine : The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dicyclomine treatment produced decreases of 38% (p = 0." | 1.35 | Dicyclomine, an M1 muscarinic antagonist, reduces biomarker levels, but not neuronal degeneration, in fluid percussion brain injury. ( Cox, CD; Hayes, RL; Liu, MC; Lyeth, BG; Wang, KK; West, EJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cox, CD | 1 |
| West, EJ | 1 |
| Liu, MC | 1 |
| Wang, KK | 1 |
| Hayes, RL | 1 |
| Lyeth, BG | 1 |
| Robinson, SE | 1 |
| Foxx, SD | 1 |
| Posner, MG | 1 |
| Martin, RM | 1 |
| Davis, TR | 1 |
| Guo, HZ | 1 |
| Enters, EK | 1 |
2 other studies available for dicyclomine and Brain Injuries
| Article | Year |
|---|---|
Dicyclomine, an M1 muscarinic antagonist, reduces biomarker levels, but not neuronal degeneration, in fluid percussion brain injury.
Topics: Animals; Biomarkers; Blotting, Western; Brain Injuries; Calpain; Caspases; Cell Death; Dicyclomine; | 2008 |
The effect of M1 muscarinic blockade on behavior and physiological responses following traumatic brain injury in the rat.
Topics: Animals; Brain Injuries; Cardiovascular System; Cyclohexanecarboxylic Acids; Dicyclomine; Male; Move | 1990 |