dicumarol and Thrombophlebitis

Arthroscopy of the knee has always been associated with a low risk of complications, including thromboembolism. Therefore, few studies have been concerned with the matter. We present two case reports and a review of the available literature concerning thromboembolic complications after arthroscopy.

Topics: Adult; Arthroscopy; Dicumarol; Drug Therapy, Combination; Heparin; Humans; Knee Injuries; Male; Menisci, Tibial; Middle Aged; Postoperative Complications; Thrombophlebitis; Tibial Meniscus Injuries

Therapeutic strategies in deep vein thrombosis are yielding possible prevention of life-threatening pulmonary thromboembolism and extension of thrombosis. In order to prevent long term sequelae, i.e., the postthrombotic syndrome, recanalization is necessary before venous valves have been destroyed. Therapeutical guidelines comprise immobilization (except isolated calf vein thrombosis), compression therapy and anticoagulation. Thrombolysis may be performed in patients in whom extension and localization of thrombosis may result in a postthrombotic syndrome, if thrombosis is not older than 1-2 weeks, if there are no concomitant diseases which make it uncertain for the patient to experience postthrombotic syndrome, and in the absence of contraindications.

Topics: Bandages; Combined Modality Therapy; Dicumarol; Drug Administration Schedule; Female; Heparin; Humans; Immobilization; Pregnancy; Pregnancy Complications, Cardiovascular; Thrombophlebitis

Topics: Anticoagulants; Bandages; Blood Flow Velocity; Dextrans; Dicumarol; Economics, Medical; Electric Stimulation; Female; Fibrinogen; Fibrinolysis; Heparin; Humans; Locomotion; Male; Middle Aged; Platelet Aggregation; Postoperative Complications; Pressure; Thrombophlebitis

Topics: Anti-Bacterial Agents; Blood Coagulation; Blood Flow Velocity; Cesarean Section; Dextrans; Dicumarol; Female; Femoral Vein; Heparin; Humans; Iliac Vein; Pelvis; Pregnancy; Pregnancy Complications, Cardiovascular; Puerperal Disorders; Pulmonary Embolism; Thrombophlebitis; Varicose Veins

Topics: Coumarins; Dicumarol; Embolism; Fibrinolysis; Fibrinolytic Agents; Heparin; Heparinoids; Humans; Myocardial Infarction; Pulmonary Embolism; Streptodornase and Streptokinase; Streptokinase; Thrombophlebitis; Thrombosis

Topics: Acenocoumarol; Angina Pectoris; Anticoagulants; Cerebrovascular Disorders; Dicumarol; Heparin; Humans; Myocardial Infarction; Phlebitis; Rheumatic Heart Disease; Thromboembolism; Thrombophlebitis; Warfarin

A consensus has not been reached about the optimal duration of oral anticoagulant therapy after a second episode of venous thromboembolism.. In a multicenter trial, we compared six months of oral anticoagulant therapy with anticoagulant therapy continued indefinitely in patients who had had a second episode of venous thromboembolism. Of 227 patients enrolled, 111 were randomly assigned to six months of anticoagulation and 116 were assigned to receive anticoagulant therapy indefinitely; for both groups, the target international normalized ratio was 2.0 to 2.85. The initial episodes of deep-vein thrombosis (n = 193) and pulmonary embolism (n = 34), as well as recurrent episodes, were all objectively confirmed.. After four years of follow-up, there were 26 recurrences of venous thromboembolism that fulfilled the diagnostic criteria, 23 in the group assigned to six months of therapy (20.7 percent) and 3 in the group assigned to continuing therapy (2.6 percent). The relative risk of recurrence in the group assigned to six months of therapy, as compared with the group assigned to therapy of indefinite duration, was 8.0 (95 percent confidence interval, 2.5 to 25.9). There were 13 major hemorrhages, 3 in the six-month group, (2.7 percent) and 10 in the infinite-treatment group (8.6 percent). The relative risk of major hemorrhage in the six-month group, as compared with the infinite-treatment group was 0.3 (95 percent confidence interval, 0.1 to 1.1). There was no difference in mortality between the two groups.. Prophylactic oral anticoagulation that was continued for an indefinite period after a second episode of venous thromboembolism was associated with a much lower rate of recurrence during four years of follow-up than treatment for six months. However, there was a trend toward a higher risk of major hemorrhage when anticoagulation was continued indefinitely.

Topics: Administration, Oral; Aged; Anticoagulants; Dicumarol; Female; Follow-Up Studies; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Probability; Pulmonary Embolism; Recurrence; Thrombophlebitis; Time Factors; Warfarin

Eighty-eight patients underwent a classical reversed saphenous vein graft for femoro-popliteal occlusive disease and were enrolled in a controlled clinical trial. During the second postoperative week the patients were allocated randomly into one of two groups: group I consisted of 42 patients who received dicumarol and group II (46 patients) served as a control group without any anticoagulant treatment. The mean follow-up time was 24 months. After 12 months the cumulative patency rate was 82%, after 18 months 76% and after 24 months 76%; for patients receiving dicumarol treatment the respective figures were 92%, 86% and 86% and for those with no treatment 70%, 67% and 67%, the difference being significant. When the bypass operation was performed for limb salvage (clinical stages III and IV) the overall results were worse (12 months: 72%, 18 months: 68%, 24 months: 68%) than in stages II, II-III (12 months: 90%, 18 months: 85%, 24 months: 85%). In limb salvage surgery the positive effects of anticoagulant treatment were significant (with treatment: 12 months 87%, 18 months 86%, 24 months 86%; without treatment: 12 months 58%, 18 months 54%, 24 months 54%).

Topics: Aged; Clinical Trials as Topic; Dicumarol; Femoral Artery; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Ischemia; Leg; Popliteal Artery; Postoperative Complications; Saphenous Vein; Thrombophlebitis

Topics: Age Factors; Aged; Anticoagulants; Cerebrovascular Disorders; Clinical Trials as Topic; Diabetes Complications; Dicumarol; Electrocardiography; Female; Heart Failure; Hemorrhage; Heparin; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Phenindione; Placebos; Pulmonary Embolism; Recurrence; Sex Factors; Thrombophlebitis; Time Factors; Warfarin

Topics: Adult; Aged; Clinical Trials as Topic; Dicumarol; Electric Stimulation; Female; Hemodynamics; Heparin; Humans; Leg; Male; Methods; Middle Aged; Postoperative Complications; Posture; Pulmonary Embolism; Statistics as Topic; Thrombophlebitis; Vena Cava, Inferior

Topics: Adult; Aged; Clinical Trials as Topic; Coronary Disease; Dicumarol; Female; Humans; Male; Middle Aged; Thrombophlebitis

Topics: Adult; Clinical Trials as Topic; Dicumarol; Heparin; Humans; Injections, Intravenous; Male; Middle Aged; Pulmonary Embolism; Streptokinase; Thrombophlebitis

In a woman patient aged 80 years under anticoagulation with dicumarol (Marcumar), abdominal pain suddenly occurred which was located on the right side as well as signs of acute bleeding. Preoperative sonography and computer scan showed a large, cystic tumour, most likely originating from the right ovary with infiltration of the abdominal wall. Intraoperative diagnosis was a large haematoma of the abdominal wall and the retroperitoneum penetrating into the free abdomen.

Topics: Abdominal Muscles; Aged; Aged, 80 and over; Diagnosis, Differential; Diagnostic Imaging; Dicumarol; Female; Hematoma; Humans; Ovarian Cysts; Retroperitoneal Space; Thrombophlebitis

Treatment of venous thrombosis during pregnancy is not without risks. Therefore diagnosis has been made by phlebography. Streptokinase therapy is accompanied with bleedings and needs a precise indication. 4 women have been operated on by thrombectomy. Dicumaroles cause fetal demages and are not suitable for prophylaxis of recurrences. Heparin is the treatment of choice, partly by self injection. During parturition a short time change to low molecular dextran is recommended.

Topics: Angioplasty, Balloon; Dicumarol; Female; Heparin; Humans; Obstetric Labor Complications; Pregnancy; Pregnancy Complications, Cardiovascular; Puerperal Disorders; Recurrence; Streptokinase; Thrombophlebitis

The experience with antithrombotic conservative treatment of 102 cases of acute thrombosis in the inferior vena cava system and in the deep veins of the lower extremities is generalized here. The suggested method permits to do away with thrombotic condition of hemostasis at a minimal risk of the occurrence of hemorrhagic complications.

Topics: Acute Disease; Adolescent; Adult; Aged; Dextrans; Dicumarol; Drug Combinations; Drug Evaluation; Female; Heparin; Humans; Infusions, Parenteral; Injections, Intramuscular; Injections, Intravenous; Leg; Male; Middle Aged; Nicotinic Acids; Thrombophlebitis

Topics: Administration, Oral; Dicumarol; Female; Heparin; Humans; Injections, Intravenous; Pregnancy; Pregnancy Complications, Hematologic; Recurrence; Thrombophlebitis

Topics: Dextrans; Dicumarol; Fibrinogen; Heparin; Humans; Iodine Radioisotopes; Leg; Phlebography; Plethysmography; Plethysmography, Impedance; Radionuclide Imaging; Thrombophlebitis

Topics: Aged; Anticoagulants; Dextrans; Dicumarol; Female; Femoral Fractures; Fibrinogen; Humans; Iodine Radioisotopes; Male; Middle Aged; Thrombophlebitis

Topics: Angina Pectoris; Anticoagulants; Aspirin; Dicumarol; Disseminated Intravascular Coagulation; Electric Countershock; Heart Valve Diseases; Humans; Myocardial Infarction; Pulmonary Embolism; Thrombophlebitis; Thrombosis; Warfarin

Topics: Adult; Aged; Anticoagulants; Aortic Aneurysm; Arteriosclerosis; Arteritis; Blood Coagulation Disorders; Blood Coagulation Tests; Diabetic Angiopathies; Dicumarol; Embolism; Female; Humans; Male; Middle Aged; Raynaud Disease; Thrombophlebitis; Thrombosis; Vascular Diseases

Topics: Aged; Dextrans; Dicumarol; Female; Heparin; Humans; Iodohippuric Acid; Leg; Male; Middle Aged; Phlebography; Postoperative Complications; Radioisotopes; Regional Blood Flow; Rheology; Serum Albumin, Radio-Iodinated; Thromboembolism; Thrombophlebitis; Time Factors; Xenon

Topics: Aged; Dextrans; Dicumarol; Female; Femoral Neck Fractures; Humans; Leg; Male; Phlebography; Preoperative Care; Thrombophlebitis

Topics: Acute Disease; Arteries; Dicumarol; Femoral Artery; Femoral Vein; Heparin; Humans; Iliac Vein; Leg; Myocardial Infarction; Pulmonary Embolism; Retinal Artery; Streptokinase; Thrombophlebitis; Thrombosis

Topics: Aged; Dicumarol; Humans; Phlebography; Recurrence; Streptokinase; Thrombophlebitis

Topics: Aged; Dextrans; Dicumarol; Female; Femoral Neck Fractures; Humans; Leg; Male; Phlebography; Postoperative Complications; Thrombophlebitis; Thrombosis; Veins

Topics: Adult; Analgesics; Blood Coagulation; Blood Coagulation Factors; Blood Coagulation Tests; Coronary Disease; Coumarins; Depression, Chemical; Dicumarol; Factor V; Factor VII; Factor X; Female; Hemostasis; Humans; Male; Middle Aged; Serotonin Antagonists; Stimulation, Chemical; Thrombophlebitis; Time Factors

Topics: Aged; Breast Diseases; Dicumarol; Edema; Female; Gangrene; Humans; Middle Aged; Necrosis; Thrombophlebitis

Topics: Administration, Oral; Anticoagulants; Dicumarol; Humans; Prothrombin Time; Thrombophlebitis; Warfarin

Topics: Adolescent; Adult; Aged; Child; Dicumarol; Diuretics; Female; Heparin; Hospitalization; Humans; Leg; Male; Middle Aged; Movement; Phlebography; Physical Therapy Modalities; Prothrombin; Pulmonary Embolism; Thrombophlebitis; Time Factors

Topics: Adrenal Cortex Hormones; Cesarean Section; Dicumarol; Estrogens; Female; Humans; Poland; Pregnancy; Pregnancy Complications; Thrombophlebitis

Topics: Adult; Aged; Anti-Bacterial Agents; Dicumarol; Ethyl Biscoumacetate; Female; Humans; Leg; Male; Middle Aged; Rest; Thrombophlebitis

Topics: Dicumarol; Humans; Phlebography; Postoperative Complications; Thrombophlebitis

Topics: Dicumarol; Diuretics; Humans; Thrombophlebitis

Topics: Adult; Anesthesia, Spinal; Antibodies; Autoimmune Diseases; Blood Coagulation Tests; Blood Protein Electrophoresis; Dicumarol; Eosinophilia; Fibrinogen; Heparin; Humans; Jaundice; Male; Pneumonia; Priapism; Pulmonary Embolism; Steroids; Thrombophlebitis; Vitamin K

Topics: Aged; Breast Diseases; Breast Neoplasms; Dicumarol; Female; Gangrene; Hemorrhage; Humans; Middle Aged; Necrosis; Pulmonary Embolism; Thrombophlebitis

Topics: Dicumarol; Humans; Thrombophlebitis; Vascular Surgical Procedures

Topics: Dicumarol; Humans; Postoperative Care; Postoperative Complications; Pulmonary Embolism; Thrombophlebitis; Warfarin

Topics: Animals; Dextrans; Dicumarol; Dogs; Drug Therapy; Heparin; Infusions, Parenteral; Molecular Weight; Sodium Chloride; Thrombophlebitis

Topics: Blood; Blood Coagulation Tests; Dicumarol; Drug Therapy; Female; Hematuria; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Thrombophlebitis; Toxicology; Uterine Hemorrhage; Vitamin K; Vitamin K 1

Topics: Acenocoumarol; Anticoagulants; Dicumarol; Drug Therapy; Heparin; Phenindione; Postoperative Complications; Preventive Medicine; Pulmonary Embolism; Thrombophlebitis; Toxicology; Venous Thrombosis; Vitamin K 1; Warfarin

Topics: Acenocoumarol; Anticoagulants; Coumarins; Dicumarol; Drug Therapy; Ecchymosis; Ethyl Biscoumacetate; Gangrene; Necrosis; Phenindione; Pulmonary Embolism; Purpura; Skin Diseases; Thrombophlebitis; Toxicology; Warfarin

Topics: Angiography; Anticoagulants; Biomedical Research; Dicumarol; Drug Therapy; Femoral Neck Fractures; Geriatrics; Humans; Phlebography; Thrombophlebitis; Veins; Venous Thrombosis

Topics: Axillary Vein; Dicumarol; Female; Femoral Vein; Heparin; Humans; Male; Pregnancy; Puerperal Disorders; Subclavian Vein; Thrombophlebitis; Vena Cava, Inferior; Warfarin

Topics: Dicumarol; Enzyme Inhibitors; Heparin; Phenindione; Postoperative Complications; Prothrombin; Thrombophlebitis; Warfarin

Topics: Anaphylaxis; Dicumarol; Fibrinolysin; Hemorrhage; Heparin; Hepatitis; Hepatitis B virus; Humans; Myocardial Infarction; Pulmonary Embolism; Thromboembolism; Thrombophlebitis; Toxicology

Topics: Abortion, Habitual; Anticoagulants; Cerebral Hemorrhage; Dicumarol; Female; Fetal Death; Heparin; Humans; Pregnancy; Pregnancy Complications, Hematologic; Thrombophlebitis; Toxicology

Topics: Anticoagulants; Breast Diseases; Dicumarol; Electrocardiography; Female; Gangrene; Hemorrhage; Humans; Lanatosides; Pregnancy; Puerperal Disorders; Rifamycins; Thrombophlebitis; Toxicology

Topics: Anticoagulants; Coronary Disease; Dicumarol; Embolism; Ethyl Biscoumacetate; Hemorrhage; Humans; Postoperative Complications; Prothrombin Time; Thrombophlebitis; Toxicology; Warfarin

Topics: Anti-Bacterial Agents; Anticoagulants; Cerebrovascular Disorders; Dicumarol; Female; Heparin; Humans; Postpartum Period; Puerperal Disorders; Thrombophlebitis

Topics: Anticoagulants; Arrhythmias, Cardiac; Blood Cell Count; Cerebrovascular Disorders; Coronary Disease; Diabetes Mellitus; Dicumarol; Heart Failure; Heparin; Humans; Hypertension; Kidney Diseases; Liver Diseases; Myocardial Infarction; Peptic Ulcer; Pulmonary Embolism; Shock; Thromboembolism; Thrombophlebitis; Thrombosis; Varicose Veins; Warfarin

Topics: Dicumarol; Female; Hemorrhage; Humans; Necrosis; Puerperal Disorders; Skin Diseases; Thrombophlebitis; Toxicology

Topics: Blood Coagulation; Dicumarol; Female; Heparin; Humans; Infant, Newborn; Injections, Intravenous; Labor, Induced; Labor, Obstetric; Oxytocin; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Prothrombin Time; Pulmonary Embolism; Sparteine; Thrombophlebitis; Toxicology; Warfarin

Topics: 4-Hydroxycoumarins; Anticoagulants; Arteriosclerosis Obliterans; Atrial Fibrillation; Biomedical Research; Coronary Disease; Dicumarol; Hypertension; Hypertension, Pulmonary; Thrombophlebitis; Toxicology

Topics: Anticoagulants; Dicumarol; Heparin; Humans; Preventive Medicine; Surgical Procedures, Operative; Thromboembolism; Thrombophlebitis; Warfarin

Topics: Dicumarol; Endometriosis; Female; Heparin; Humans; Leg; Norethynodrel; Pelvic Neoplasms; Pharmacology; Thrombophlebitis

Topics: Anticoagulants; Dicumarol; Fibrinolysis; Heparin; Humans; Pulmonary Embolism; Thrombophlebitis

Topics: Anticoagulants; Antisepsis; Dicumarol; Female; Heparin; Humans; Obstetrics; Postoperative Care; Pregnancy; Puerperal Disorders; Thrombophlebitis

Topics: Casts, Surgical; Dicumarol; Femoral Vein; Fracture Fixation; Fractures, Bone; Heparin; Humans; Iliac Vein; Injections, Intravenous; Leg; Leg Injuries; Thrombophlebitis; Warfarin

Topics: Anticoagulants; Dicumarol; Heparin; Thrombophlebitis; Venous Thrombosis

Topics: Dicumarol; Female; Pregnancy; Pregnancy Complications; Thrombophlebitis

Topics: Anticoagulants; Blood Coagulation; Dicumarol; Extremities; Humans; Thrombophlebitis

Topics: Dicumarol; Humans; Thrombophlebitis; Venous Thrombosis

Topics: Dicumarol; Humans; Lower Extremity; Thrombophlebitis

Topics: Dicumarol; Female; Humans; Pregnancy; Pregnancy Complications; Thrombophlebitis

Topics: Blood Coagulation; Coumarins; Dicumarol; Female; Humans; Postpartum Period; Thrombophlebitis

Topics: Coumarins; Dicumarol; Extremities; Thrombophlebitis

Topics: Climacteric; Coumarins; Dicumarol; Female; Humans; Leiomyoma; Menopause; Menorrhagia; Metrorrhagia; Thrombophlebitis; Uterine Neoplasms

Topics: Coumarins; Dicumarol; Thrombophlebitis; Thrombosis

Topics: Acetates; Blood Coagulation Tests; Coumarins; Dicumarol; Heparin; Humans; Thrombophlebitis; Venous Thrombosis

Topics: Animals; Child; Coumarins; Dicumarol; Female; Fetus; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Pregnancy; Pregnancy Complications; Thrombophlebitis

Topics: Anticoagulants; Dicumarol; Disease Susceptibility; Hematologic Diseases; Hemophilia A; Hemorrhagic Disorders; Heparin; Humans; Liver Diseases; Purpura, Thrombocytopenic; Purpura, Thrombocytopenic, Idiopathic; Syndrome; Thrombophlebitis

Topics: Antipyretics; Dicumarol; Pelvis; Thrombophlebitis

Topics: Anticoagulants; Dicumarol; Embolism; Heparin; Pulmonary Embolism; Thrombophlebitis

Topics: Dicumarol; Heparin; Humans; Thrombophlebitis; Thromboplastin; Thrombosis; Venous Thrombosis

Topics: Anticoagulants; Dicumarol; Heparin; Pulmonary Embolism; Thrombophlebitis

Topics: Dicumarol; Female; Humans; Pregnancy; Thrombophlebitis; Venous Thrombosis

Topics: Anticoagulants; Dicumarol; Thromboembolism; Thrombophlebitis

Topics: Anticoagulants; Dicumarol; Heparin; Thrombophlebitis

Topics: Anticoagulants; Dicumarol; Female; Heparin; Humans; Postpartum Period; Thrombophlebitis

Topics: Coronary Thrombosis; Dicumarol; Heparin; Humans; Pulmonary Embolism; Thrombophlebitis

Topics: Dicumarol; Thrombophlebitis

Topics: Anticoagulants; Coumarins; Dicumarol; Heparin; Humans; Thrombophlebitis; Thrombosis; Venous Thrombosis