dicumarol and Heart-Failure

dicumarol has been researched along with Heart-Failure* in 20 studies

Reviews

1 review(s) available for dicumarol and Heart-Failure

ArticleYear
[THERAPY OF THROMBOEMBOLISM. 1].
    Medizinische Klinik, 1963, Nov-08, Volume: 58

    Topics: Dicumarol; Heart Failure; Heparin; Humans; Hydrocortisone; Muscle Relaxants, Central; Norepinephrine; Pulmonary Embolism; Thromboembolism

1963

Trials

1 trial(s) available for dicumarol and Heart-Failure

ArticleYear
Anticoagulant therapy after acute myocardial infarction. Relation of therapeutic benefit to patient's age, sex, and severity of infarction.
    JAMA, 1972, Oct-30, Volume: 222, Issue:5

    Topics: Age Factors; Aged; Anticoagulants; Cerebrovascular Disorders; Clinical Trials as Topic; Diabetes Complications; Dicumarol; Electrocardiography; Female; Heart Failure; Hemorrhage; Heparin; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Phenindione; Placebos; Pulmonary Embolism; Recurrence; Sex Factors; Thrombophlebitis; Time Factors; Warfarin

1972

Other Studies

18 other study(ies) available for dicumarol and Heart-Failure

ArticleYear
Analysis of factors affecting limb salvage and mortality after embolectomy.
    Acta chirurgica Scandinavica, 1977, Volume: 143, Issue:4

    A series of 108 arterial embolectomies in 91 patients performed during 1960-64 and 1970-74 is presented. The Fogarty catheter was introduced in our clinic between these periods. Early mortality was 56 and 29%, respectively. Limb salvage rate according to our definition was 38 and 53%, respectively. We found a significantly higher mortality when embolies were located proximal to the profunda femoral artery compared to more distally located embolies. Amputation frequency was 4% after embolectomies performed within 12 hours, but 27% with longer duration of symptoms. Limb salvage rate was significantly higher in patients treated with anticoagulation. In conclusion it is stressed that local surgical therapy should be combined with adequate measures against cardiac failure and other systemic complications. This therapeutic principle is particularly important in cases with proximal embolies.

    Topics: Aged; Amputation, Surgical; Arm; Dicumarol; Embolism; Female; Heart Failure; Heparin; Humans; Leg; Male; Middle Aged; Myocardial Infarction; Postoperative Complications; Pulmonary Embolism; Time Factors

1977
Isolated mitral valve replacement with the Björk-Shiley tilting disc valve prosthesis. A six-year review and a comparison between the Delrin and the pyrolytic carbon disc models.
    Scandinavian journal of thoracic and cardiovascular surgery, 1977, Volume: 11, Issue:3

    Replacement of the mitral valve with the Björk-Shiley tilting disc valve prosthesis was performed in 203 consecutive patients with isolated mitral valvular disease at Karolinska Sjukhuset, Stockholm, Sweden, during the 6-year period ending December 1975. Results with the Delrin and pyrolytic carbon disc prostheses were analysed with actuarial techniques and compared in terms of mortality rate, incidence of thrombo-embolism and frequency of re-operation. Early (4%) and late mortality rates (7.5 deaths per 100 patient years) were similar with both types of prostheses. No case of primary mechanical prosthetic failure was encountered. The pyrolytic carbon disc prostheses have obviously decreased the incidence of systemic emboli from 9.6 to 5.3 per 100 patient years and so far eliminated mortality due to embolization. This benefit is probably related to the increased opening angle from 50 degrees to 60 degrees in the pyrolytic carbon disc model, which causes less resistance to blood flow. Thrombotic obstruction of the prosthetic valve, however, has been a persistent problem in the order of 3.3 incidences per 100 patient years. Only one patient in twelve involved was referred to our clinic and could be saved by an emergency re-operation. The development of the ring-shaped radiopaque marker in the tilting disc occluder provides a valuable tool for instant diagnosis of partly or completely obstructed disc motion caused by thrombosis. Disc motion can be easily visualized by cineradiography or fluoroscopy. Early diagnosis of and emergency operation for thrombotic obstruction of the prosthesis will reduce the mortality due to this dangerous complication.

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Child; Dicumarol; Evaluation Studies as Topic; Female; Follow-Up Studies; Heart Failure; Heart Valve Prosthesis; Humans; Male; Middle Aged; Mitral Valve; Myocardial Infarction; Thromboembolism; Time Factors; Warfarin

1977
Recurrent haemolytic uraemic syndrome.
    Padiatrie und Padologie, 1976, Volume: 11, Issue:3

    Two children are described with frequent relapsing haemolytic uraemic syndrome. In the first child, the disease reoccurred twice and in the second three times. In both, relapses could be related to a viral infection, as well as to a preceding inoculation for diphtheria--pertussis--tetanus--poliomyelitis in the second patient. Recurrent haemolytic-uraemic syndrome (H.U.S.) may constitute a discrete clinical form of H.U.S.

    Topics: Adenoviridae; Antibodies, Viral; Anticoagulants; Aspirin; Child, Preschool; Dicumarol; Diphtheria Toxoid; Enterovirus B, Human; Feces; Heart Failure; Hemolytic-Uremic Syndrome; Heparin; Humans; Male; Nasal Mucosa; Peritoneal Dialysis; Pertussis Vaccine; Poliovirus Vaccine, Inactivated; Purpura, Thrombotic Thrombocytopenic; Recurrence; Streptokinase; Tetanus Toxoid

1976
Role of mitochondrial calcium transport in failing heart.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 5

    Mitochondrial calcium uptake, but not binding, like microsomal calcium uptake in failing human hearts, was less than the control values for dog, rabbit, and hamster hearts. Decrease in mitochondrial calcium binding and uptake was observed in genetically myopathic hamsters (BIO 14.6) at early, moderate, and late stages of congestive heart failure. Inhibitors of mitochondrial calcium transport, Dicumarol, dinitrophenol, and sodium azide, were found to produce a rapid fall in contractility of the isolated rat heart. Inability of rat hearts to generate contractile force on perfusion with Na+- or K+-free medium was associated with an increase in mitochondrial calcium uptake. A dramatic increase in mitochondrial calcium uptake was observed on perfusing rat hearts with control medium after CA++-free medium. No change in mitochondrial calcium uptake was noted in acute ischemic dog myocardium or hypoxic rat heart in which contractile force was severely depressed. Both mitochondrial calcium transport and contractility were decreased on perfusing rat hearts with substrate-free medium; however, the change in calcium uptake was secondary to the fall in contractile force. Decrease in pH, ATP:ADP ratio, ATP6AMP ratio, and K+:Na+ ratio were found to reduce the dog heart mitochondrial calcium uptake. It is likely that various factors such as pH, ATP:ADP ration, ATP:AMP ratio, and K+ :Na+ ration, in addition to damage in mitochondrial structure, play an important role in inhibiting mitochondrial calcium transport in failing hearts. The results also suggest that alterations in mitochondrial calcium transport are dependent upon the degree and type of heart failure.

    Topics: Adenine Nucleotides; Animals; Azides; Binding Sites; Biological Transport; Calcium; Cricetinae; Dicumarol; Dinitrophenols; Dogs; Heart Failure; Humans; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Metals, Alkali; Mitochondria, Muscle; Myocardial Contraction; Myocardium; Papillary Muscles; Rabbits; Sarcoplasmic Reticulum

1975
The low incidence of coronary thrombosis: a poor target for long-term anticoagulants.
    Geriatrics, 1971, Volume: 26, Issue:1

    Topics: Acute Disease; Adult; Anticoagulants; Arrhythmias, Cardiac; Chronic Disease; Coronary Disease; Dicumarol; Female; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Prothrombin Time; Thrombelastography; Thrombosis; Warfarin

1971
Long term oral anticoagulation following myocardial infarction. A Veterans Administration cooperative study.
    Thrombosis et diathesis haemorrhagica. Supplementum, 1966, Volume: 21

    Topics: Adult; Aged; Angina Pectoris; Anticoagulants; Diabetes Mellitus; Dicumarol; Follow-Up Studies; Heart Failure; Humans; Hypertension; Interprofessional Relations; Intracranial Embolism and Thrombosis; Kidney Diseases; Male; Middle Aged; Myocardial Infarction; Peptic Ulcer; United States; United States Department of Veterans Affairs

1966
CLINICAL MANAGEMENT OF MYOCARDIAL INFARCTION.
    JAMA, 1965, Jan-11, Volume: 191

    Topics: Arrhythmias, Cardiac; Dicumarol; Diet; Diet Therapy; Heart Failure; Heart Massage; Heparin; Humans; Meperidine; Morphine; Myocardial Infarction; Oxygen Inhalation Therapy; Rest; Therapeutics; Thromboembolism; Ventricular Fibrillation

1965
ANTICOAGULANT DRUG THERAPY IN ACUTE CORNONARY THROMBOSIS AND ALLIED CONDITIONS.
    Diseases of the chest, 1964, Volume: 45

    Topics: Anticoagulants; Arrhythmias, Cardiac; Blood Cell Count; Cerebrovascular Disorders; Coronary Disease; Diabetes Mellitus; Dicumarol; Heart Failure; Heparin; Humans; Hypertension; Kidney Diseases; Liver Diseases; Myocardial Infarction; Peptic Ulcer; Pulmonary Embolism; Shock; Thromboembolism; Thrombophlebitis; Thrombosis; Varicose Veins; Warfarin

1964
Anticoagulation therapy for congestive heart failure.
    Acta medica Scandinavica, 1957, Sep-06, Volume: 158, Issue:3-4

    Topics: Dicumarol; Health Services; Heart Failure; Humans

1957
Vitamin K control of the increased hypoprothrombinemic effect of dicumarol in congestive heart failure.
    The American journal of the medical sciences, 1952, Volume: 224, Issue:4

    Topics: Coumarins; Dicumarol; Heart Failure; Humans; Sexually Transmitted Diseases; Vitamin K

1952
Therapeutics and toxicology.
    Annual review of medicine, 1950, Volume: 1

    Topics: Anemia; Anemia, Pernicious; Antacids; Anti-Bacterial Agents; Arthritis; Arthritis, Rheumatoid; Blood Pressure; Cortisone; Dibenzylchlorethamine; Dicumarol; Epilepsy; Ergot Alkaloids; Heart Failure; Heparin; Histamine Antagonists; Humans; Hyaluronoglucosaminidase; Hydantoins; Hypersensitivity; Hypertension; Hyperthyroidism; Imidazoles; Iodine; Iodine Isotopes; Kidney; Meperidine; Mephenesin; Methadone; Motion Sickness; Norepinephrine; Organomercury Compounds; Peptic Ulcer; Tetraethylammonium; Therapeutics; Thiouracil; Thrombosis; Veratrum; Vitamin B 12

1950
Anticoagulant therapy in heart disease. A summary of the literature.
    California medicine, 1950, Volume: 73, Issue:5

    Considerable experience by many independent workers with the use of anticoagulants in the treatment of certain types of heart disease has shown that such therapy reduces significantly the incidence of thromboembolic complications and, largely through this effect, the morbidity and mortality rate from heart disease of these types. This is certainly established in acute coronary occlusion with myocardial infarction and in those instances of rheumatic heart disease with auricular fibrillation in which repeated embolic phenomena have occurred. The case for the administration of the anticoagulants in congestive heart failure is less secure, although there is no doubt that the number of thromboembolic complications is reduced by use of them. The administration of the anticoagulants requires considerably more exacting attention than does the administration of the majority of therapeutic agents in use commonly today. Hence, it is suggested that the use of anticoagulants in heart disease be restricted to those instances in which the indications are clear and facilities are compatible with the efficient and safe use of the drug, whether Dicumarol or heparin.

    Topics: Anticoagulants; Atrial Fibrillation; Cardiovascular Diseases; Dicumarol; Heart Diseases; Heart Failure; Heparin; Humans; Myocardial Infarction; Rheumatic Heart Disease

1950
Dicumarol prophylaxis of thromboembolic disease in congestive heart failure.
    The New England journal of medicine, 1950, Feb-09, Volume: 242, Issue:6

    Topics: Dicumarol; Heart; Heart Failure; Humans; Thromboembolism

1950
The effect of dicumarol upon the mortality and incidence of thromboembolic complications in congestive heart failure.
    American heart journal, 1950, Volume: 39, Issue:5

    Topics: Dicumarol; Heart; Heart Failure; Humans; Incidence

1950
Dicumarol in congestive heart failure.
    America clinica, 1949, Volume: 14, Issue:5

    Topics: Dicumarol; Heart Failure

1949
The increased hypoprothrombinemic effect of a small dose of dicumarol in congestive heart failure.
    The American journal of the medical sciences, 1949, Volume: 218, Issue:3

    Topics: Dicumarol; Heart Failure; Humans

1949
Dicumarol therapy in congestive heart failure.
    The New England journal of medicine, 1948, Nov-04, Volume: 239, Issue:19

    Topics: Dicumarol; Heart Failure; Humans

1948
The use of dicumarol as an adjunct to the treatment of congestive heart failure; results in a controlled series of 61 cases.
    Southern medical journal, 1948, Volume: 41, Issue:4

    Topics: Cardiovascular System; Dicumarol; Disease Susceptibility; Heart Failure; Humans

1948
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