dictyoceratin-c and Prostatic-Neoplasms

dictyoceratin-c has been researched along with Prostatic-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for dictyoceratin-c and Prostatic-Neoplasms

ArticleYear
Enantioselective synthesis of dictyoceratin-A (smenospondiol) and -C, hypoxia-selective growth inhibitors from marine sponge.
    Bioorganic & medicinal chemistry, 2015, Mar-01, Volume: 23, Issue:5

    Total syntheses of (+)-dictyoceratin-C (1) and (+)-dictyoceratin-A (smenospondiol) (2), hypoxia-selective growth inhibitors isolated from marine sponge, were executed. The absolute stereochemistry of the each compound was determined through the enantioselective total syntheses of them. It revealed that the unnatural enantiomers of them also exhibited the hypoxia-selective growth inhibitory activity against human prostate cancer DU-145 cells.

    Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Growth Inhibitors; Humans; Hydroxybenzoates; Male; Marine Biology; Porifera; Prostatic Neoplasms; Sesquiterpenes; Stereoisomerism

2015